piperidines has been researched along with divinyl-sulfone* in 1 studies
1 other study(ies) available for piperidines and divinyl-sulfone
| Article | Year |
|---|---|
Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone.
The asymmetric dihydroxylation of amino-functionalized vinyl sulfone 19 has been used for the 3-step preparation of 3-hydroxylpiperidine 24 in 86% enantiomeric excess. This enantiomerically enriched building block was used then to synthesize the naturally occurring antimalarial alkaloid febrifugine 1 and its antiangiogenic analogue, halofuginone 3. Topics: Catalysis; Hydroxylation; Molecular Structure; Piperidines; Quinazolines; Quinazolinones; Stereoisomerism; Sulfones | 2010 |