piperidines and deplancheine

piperidines has been researched along with deplancheine* in 1 studies

Other Studies

1 other study(ies) available for piperidines and deplancheine

ArticleYear
Convenient synthesis of substituted piperidinones from alpha,beta-unsaturated amides: formal synthesis of deplancheine, tacamonine, and paroxetine.
    The Journal of organic chemistry, 2005, May-13, Volume: 70, Issue:10

    [reaction: see text] An intermolecular aza-double Michael reaction leading to functionalized piperidin-2-ones from simple starting materials has been developed. The method allows alpha,beta-unsaturated amides to be used as a synthon of the piperidine nucleus. In addition, the utility of this methodology is demonstrated by its application to a formal synthesis of the indolo[2,3-a]quinolizidine alkaloids, (+/-)-deplancheine, (+/-)-tacamonine, and the antidepressant paroxetine.

    Topics: Amides; Antidepressive Agents, Second-Generation; Indole Alkaloids; Paroxetine; Piperidines; Stereoisomerism

2005