piperidines and coralyne

piperidines has been researched along with coralyne* in 1 studies

Other Studies

1 other study(ies) available for piperidines and coralyne

ArticleYear
Natural and synthetic G-quadruplex interactive berberine derivatives.
    Bioorganic & medicinal chemistry letters, 2006, Mar-15, Volume: 16, Issue:6

    The interaction of the natural alkaloid berberine with various G-quadruplex DNA structures and its ability to inhibit telomerase have been examined and compared with those of a synthetic piperidino derivative and the related compound coralyne. The results show that these molecules have selectivity for G-quadruplex compared to duplex DNA, and that their aromatic moieties play a dominant role in quadruplex binding.

    Topics: Antineoplastic Agents; Berberine Alkaloids; DNA; Humans; Intercalating Agents; Ligands; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Piperidines; Telomerase; Telomere

2006