piperidines has been researched along with coralyne* in 1 studies
1 other study(ies) available for piperidines and coralyne
Article | Year |
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Natural and synthetic G-quadruplex interactive berberine derivatives.
The interaction of the natural alkaloid berberine with various G-quadruplex DNA structures and its ability to inhibit telomerase have been examined and compared with those of a synthetic piperidino derivative and the related compound coralyne. The results show that these molecules have selectivity for G-quadruplex compared to duplex DNA, and that their aromatic moieties play a dominant role in quadruplex binding. Topics: Antineoplastic Agents; Berberine Alkaloids; DNA; Humans; Intercalating Agents; Ligands; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Piperidines; Telomerase; Telomere | 2006 |