piperidines has been researched along with bromobenzene* in 2 studies
2 other study(ies) available for piperidines and bromobenzene
| Article | Year |
|---|---|
Synthesis of [
Convenient and straightforward synthesis of ibrutinib labeled by carbon-13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated yield (7%) of [ Topics: Adenine; Bromobenzenes; Carbon Isotopes; Chemistry Techniques, Synthetic; Piperidines; Protein Kinase Inhibitors | 2021 |
A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore.
Syntheses of two 4-phenylpiperidines from bromobenzene have been developed involving anchoring to a fluorous-tag, Ir-catalysed borylation, Pd- and Co-catalysed elaboration then traceless cleavage. Although performed using 'cold' (i.e. unlabelled) bromobenzene as the starting material, these routes have been designed to minimise material loss via volatile intermediates and expedite purification during radiosynthesis from 'hot' (i.e. [(14)C] labelled) bromobenzene. Topics: Boron; Bromobenzenes; Catalysis; Iridium; Isotopes; Piperidines; Radiochemistry; Volatilization | 2008 |