piperidines has been researched along with bicyclo(3.3.1)nonane* in 1 studies
1 other study(ies) available for piperidines and bicyclo(3.3.1)nonane
Article | Year |
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Asymmetric construction of quaternary centers by enantioselective allylation: application to the synthesis of the serotonin antagonist LY426965.
[reaction: see text] Catalytic enantioselective allylation with a chiral bisphosphoramide was applied to the synthesis of LY426965, a serotonin antagonist. The key step, addition of a 3,3-disubstituted allyltrichlorosilane to benzaldehyde, provided the adduct containing a stereogenic quaternary center with excellent diastereoselectivity and enantioselectivity. Topics: Bridged Bicyclo Compounds; Bridged-Ring Compounds; Catalysis; Indicators and Reagents; Piperidines; Serotonin Antagonists; Stereoisomerism | 2002 |