piperidines and amonafide

piperidines has been researched along with amonafide* in 1 studies

Other Studies

1 other study(ies) available for piperidines and amonafide

Article	Year
Lysosomes-targeting imaging and anticancer properties of novel bis-naphthalimide derivatives. Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4 A series of novel N,N-bis(3-aminopropyl)methylamine bridged bis-naphthalimide derivatives NI1-NI8 containing saturated nitrogenous heterocycles were designed and synthesized, their cytotoxic activities against Hela, MCF-7, A549 and MGC-803 cells were investigated, Compounds NI1-NI4 modified with piperidine and piperazine exhibited good and selective cytotoxic activity, for instance, compounds NI1 and NI4 showed potent cytotoxic activity against Hela cells and MGC-803 cells with the IC Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA; Drug Screening Assays, Antitumor; Fluorescence; Fluorescent Dyes; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Nucleic Acid Conformation; Organophosphonates; Piperazines; Piperidines; S Phase Cell Cycle Checkpoints; Transition Temperature; Zebrafish	2018

Article

Year

Lysosomes-targeting imaging and anticancer properties of novel bis-naphthalimide derivatives.

Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

A series of novel N,N-bis(3-aminopropyl)methylamine bridged bis-naphthalimide derivatives NI1-NI8 containing saturated nitrogenous heterocycles were designed and synthesized, their cytotoxic activities against Hela, MCF-7, A549 and MGC-803 cells were investigated, Compounds NI1-NI4 modified with piperidine and piperazine exhibited good and selective cytotoxic activity, for instance, compounds NI1 and NI4 showed potent cytotoxic activity against Hela cells and MGC-803 cells with the IC

Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA; Drug Screening Assays, Antitumor; Fluorescence; Fluorescent Dyes; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Nucleic Acid Conformation; Organophosphonates; Piperazines; Piperidines; S Phase Cell Cycle Checkpoints; Transition Temperature; Zebrafish

2018