piperidines and 5-amino-5-deoxygalactopyranose

piperidines has been researched along with 5-amino-5-deoxygalactopyranose* in 1 studies

Other Studies

1 other study(ies) available for piperidines and 5-amino-5-deoxygalactopyranose

Article	Year
A concise enantioselective entry to the synthesis of deoxy-azasugars. Organic letters, 2000, Volume: 2, Issue:1 [reaction: see text] A concise enantioselective preparation of oxazolidinylpiperidine 4, a key intermediate in the synthesis of glycosidase inhibitors such as 1-deoxymannojirimycin or 1-deoxygalactostatin, has been developed. Sharpless catalytic asymmetric epoxidation of (E)-2,4-pentadienol followed by treatment with allyl isocyanate afforded epoxy carbamate 8. Regioselective intramolecular ring opening promoted by sodium bis(trimethylsilyl)amide and ring-closing metathesis provided the bicyclic intermediate 4 in high enantiomeric purity. The four-step sequence takes place in 51% overall yield. Topics: 1-Deoxynojirimycin; Aza Compounds; Deoxy Sugars; Enzyme Inhibitors; Galactosamine; Glycoside Hydrolases; Molecular Structure; Piperidines; Stereoisomerism	2000

Article

Year

A concise enantioselective entry to the synthesis of deoxy-azasugars.

Organic letters, 2000, Volume: 2, Issue:1

[reaction: see text] A concise enantioselective preparation of oxazolidinylpiperidine 4, a key intermediate in the synthesis of glycosidase inhibitors such as 1-deoxymannojirimycin or 1-deoxygalactostatin, has been developed. Sharpless catalytic asymmetric epoxidation of (E)-2,4-pentadienol followed by treatment with allyl isocyanate afforded epoxy carbamate 8. Regioselective intramolecular ring opening promoted by sodium bis(trimethylsilyl)amide and ring-closing metathesis provided the bicyclic intermediate 4 in high enantiomeric purity. The four-step sequence takes place in 51% overall yield.

Topics: 1-Deoxynojirimycin; Aza Compounds; Deoxy Sugars; Enzyme Inhibitors; Galactosamine; Glycoside Hydrolases; Molecular Structure; Piperidines; Stereoisomerism

2000