piperidines has been researched along with 4-hydroxypipecolic-acid* in 2 studies
2 other study(ies) available for piperidines and 4-hydroxypipecolic-acid
| Article | Year |
|---|---|
The vinylfluoro group as an acetonyl cation equivalent: stereoselective synthesis of 6-substituted 4-hydroxy pipecolic acid derivatives.
An unprecedented cascade of reactions after acid-catalyzed hydrolysis of tert-butyl (2S,5S)-2-tert-butyl-5-(2-fluoroallyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 3a leading to pipecolic acid derivative 5 is presented. The vinylfluoro group is shown to be an acetonyl cation equivalent under acidic conditions. Interestingly, vinylchloro and vinylbromo groups do not show such transformation under the same conditions. The pipecolic acid derivative 5 produced in this way is further used to synthesize (2R,4R,6S)-6-tert-butyl-4-hydroxypiperidine-2-carboxylic acid 9. Topics: Carboxylic Acids; Cations; Imidazolidines; Molecular Structure; Pipecolic Acids; Piperidines; Stereoisomerism; Structure-Activity Relationship; Vinyl Compounds | 2010 |
Occurrence of 4-hydroxypipecolic acid in Acacia species.
Topics: Acacia; Pipecolic Acids; Piperidines | 1959 |