piperidines has been researched along with 1-1-diphenylethylene* in 1 studies
1 other study(ies) available for piperidines and 1-1-diphenylethylene
| Article | Year |
|---|---|
Hydroaminomethylation with novel rhodium-carbene complexes: an efficient catalytic approach to pharmaceuticals.
Starting from [{Rh(cod)Cl}(2)] and 1,3-dimesitylimidazole-2-ylidenes the novel [RhCl(cod)(carbene)] complexes 1-5 have been synthesized, characterized, and tested in the hydroaminomethylation of aromatic olefins. The influence of different ligands and reaction parameters on the catalytic activity was investigated in detail applying 1,1-diphenylethylene and piperidine as a model system. The scope and limitations of the novel catalysts is shown in the preparation of 16 biologically active 1-amino-3,3-diarylpropenes. In general, high chemo- and regioselectivity as well as good yields of the desired products were achieved. Topics: Alkenes; Amines; Catalysis; Hydrocarbons; Imidazoles; Ligands; Methane; Methylation; Models, Chemical; Molecular Structure; Organometallic Compounds; Pharmaceutical Preparations; Piperidines; Propane; Rhodium; Styrenes | 2007 |