Page last updated: 2024-08-18

piperidine and isoxazoles

piperidine has been researched along with isoxazoles in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Fotsch, C; St Jean, DJ1
Corniquet, XG; Marsh, GP; McCarthy, C; Parsons, PJ1
Alper, PB; Bao, D; Bursulaya, B; Chianelli, D; Groessl, T; Joseph, SB; Kim, Y; Laffitte, B; Liu, B; McNamara, P; Molteni, V; Mutnick, D; Phimister, A; Rucker, PV; Schmeits, J; Seidel, HM; Tully, DC; Vidal, A; Williams, J; Wu, X; Zoll, J1
Aparna, P; Bhavani, AKD; Gautier, F; Grée, R; Juin, P; Le Guevel, R; Levoin, N; Mosset, P; Murthy, AVR; Narendar, V; Reddy, CR; Roul, J; Sampath Kumar, N; Solhi, H1

Reviews

1 review(s) available for piperidine and isoxazoles

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012

Other Studies

3 other study(ies) available for piperidine and isoxazoles

ArticleYear
An efficient synthesis of nitroalkenes by alkene cross metathesis: facile access to small ring systems.
    Organic letters, 2007, Jul-05, Volume: 9, Issue:14

    Topics: Alkenes; Cyclization; Cyclopentanes; Indicators and Reagents; Isoxazoles; Nitro Compounds; Piperidines

2007
Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Administration, Oral; Animals; Benzothiazoles; Biological Availability; Cholestasis; Dogs; Drug Evaluation, Preclinical; Fibroblast Growth Factors; Gene Expression Regulation; Humans; Isoxazoles; Male; Microsomes, Liver; Non-alcoholic Fatty Liver Disease; Piperidines; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Triglycerides

2017
Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.
    Bioorganic & medicinal chemistry letters, 2021, 11-15, Volume: 52

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Models, Molecular; Molecular Structure; Piperidines; Structure-Activity Relationship; Triazoles

2021