piperazine has been researched along with olaparib in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsieh, CJ; Mach, RH; Makvandi, M; Puentes, LN; Reilly, SW; Weng, CC; Wilson, K | 1 |
| Abuelizz, HA; Alsubi, TA; Attwa, MW; Darwish, HW; Kadi, AA | 1 |
2 other study(ies) available for piperazine and olaparib
| Article | Year |
|---|---|
Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity.
Topics: Animals; BRCA1 Protein; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; Mice, Knockout; Molecular Docking Simulation; Phthalazines; Piperazine; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship | 2018 |
Piperazine ring toxicity in three novel anti-breast cancer drugs: an in silico and in vitro metabolic bioactivation approach using olaparib as a case study.
Topics: Animals; Antineoplastic Agents; Chromatography, Liquid; Neoplasms; Piperazine; Piperazines; Rats; Tandem Mass Spectrometry | 2023 |