piperazine has been researched along with morpholine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fotsch, C; St Jean, DJ | 1 |
| Barthalmus, GT; Mitchell, MK; Noga, EJ | 1 |
| Glinka, R; Guryn, R; Kotełko, B; Mikołajewska, H | 1 |
| Kiełek, MB; Kusowska, J; Szadowska, A; Wejman, I | 1 |
| Das, MM; Lalitha, M; Murthy, BN; Prabhakar, T; Rao, GB; Rao, NS | 1 |
| Allan, DR; McGregor, PA; Motherwell, WD; Oswald, ID; Parsons, S; Pulham, CR | 1 |
| Chen, DM; Chen, K; Wang, H | 1 |
| ROBERTI, V | 1 |
| Durgun, M; Emul, M; Innocenti, A; Scozzafava, A; Supuran, CT; Turkmen, H; Vullo, D; Yilmaztekin, S | 1 |
| D'hooghe, M; De Kimpe, N; Van Brabandt, W; Vanwalleghem, M | 1 |
| Cincić, D; Friscić, T; Jones, W | 1 |
| Demirbas, A; Demirbas, N; Karaoglu, SA; Sahin, D | 1 |
| Brun, R; Davies, J; Kaiser, M; Lander, H; Leung, SC; O'Neill, PM; Pacorel, B; Stachulski, AV; Vivas, L; Ward, SA | 1 |
| Arion, VB; Bacher, F; Chugunova, A; Dömötör, O; Enyedy, ÉA; Filipović, L; Nagy, NV; Radulović, S | 1 |
| Jewell, KS; Lutze, HV; Reisz, E; Schmidt, TC; Schmidt, W; Tekle-Röttering, A; Ternes, TA | 1 |
| Kantevari, S; Pulipati, L; Sriram, D; Yogeeswari, P | 1 |
| Dong, B; Kong, X; Lin, W; Song, W; Wang, C; Zhang, N | 1 |
| Chernykh, AV; Daniliuc, CG; Feskov, IO; Grygorenko, OO; Kondratov, IS; Kuchkovska, YO | 1 |
| Kantevari, S; Krishna, VS; Marvadi, SK; Sriram, D | 1 |
1 review(s) available for piperazine and morpholine
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
18 other study(ies) available for piperazine and morpholine
| Article | Year |
|---|---|
Cyclic amines are selective cytotoxic agents for pigmented cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Drug Synergism; Melanins; Melanoma; Mice; Morpholines; Pigmentation; Piperazine; Piperazines; Piperidines; Theophylline | 1986 |
[Synthesis of derivatives of perhydroazepine, perhydro-1,5-oxazocine, morpholine and piperazine containing 3-(isopropylamino)-propan-2-ol group--compounds with potential effect on the circulatory system and central nervous system].
Topics: Azepines; Blood Circulation; Central Nervous System; Humans; Morpholines; Oxazocines; Piperazine; Piperazines | 1985 |
[Effect on the central nervous system and circulatory system of new derivatives of perhydroazepine, perhydro-1,5-oxazocine, morpholine and piperazine containing a pharmacophoric 3-(isopropylamino)-propan-2-ol group].
Topics: Animals; Antihypertensive Agents; Azepines; Blood Pressure; Female; Male; Mice; Mice, Inbred BALB C; Morpholines; Motor Activity; Oxazocines; Piperazine; Piperazines; Propanolamines; Rats; Tranquilizing Agents | 1985 |
Natural abundance nitrogen-15 nuclear magnetic resonance spectral studies on selected donors.
Topics: Amines; Heterocyclic Compounds; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Morpholines; Nitrogen Isotopes; Piperazine; Piperazines; Piperidines; Solvents | 2002 |
The formation of paracetamol (acetaminophen) adducts with hydrogen-bond acceptors.
Topics: Acetaminophen; Calorimetry, Differential Scanning; Crystallography, X-Ray; Hydrogen Bonding; Morpholines; Piperazine; Piperazines | 2002 |
[Antithrombotic effects of morpholine and piperazine ring derivatives and their molecular mechanism].
Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Female; Fibrinolytic Agents; Male; Mice; Morpholines; Piperazine; Piperazines; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Rats; Rats, Wistar; Tissue Plasminogen Activator; Vasodilator Agents | 2003 |
[Monoethylamine, triethanolamine, morpholine and piperazine in qualitative analysis--Note II].
Topics: Ethanolamines; Humans; Morpholines; Piperazine; Piperazines | 1950 |
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
Topics: Acetazolamide; Amines; Biomarkers, Tumor; Carbonic Anhydrase Inhibitors; Catalysis; Cytosol; Heterocyclic Compounds; Humans; Isoenzymes; Morpholines; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides | 2005 |
Asymmetric synthesis of 1-(2- and 3-haloalkyl)azetidin-2-ones as precursors for novel piperazine, morpholine, and 1,4-diazepane annulated beta-lactams.
Topics: Azetidines; beta-Lactams; Chemistry, Organic; Magnetic Resonance Spectroscopy; Molecular Structure; Morpholines; Piperazine; Piperazines | 2006 |
Isostructural materials achieved by using structurally equivalent donors and acceptors in halogen-bonded cocrystals.
Topics: Crystallization; Fluorobenzenes; Heterocyclic Compounds, 1-Ring; Hydrogen Bonding; Models, Molecular; Molecular Structure; Morpholines; Piperazine; Piperazines; Powder Diffraction | 2008 |
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.
Topics: Anti-Infective Agents; Bacteria; Drug Design; Fungi; Mannich Bases; Morpholines; Piperazine; Piperazines; Triazoles | 2009 |
Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Inhibitory Concentration 50; Morpholines; Piperazine; Piperazines; Plasmodium falciparum; Pyrroles; Structure-Activity Relationship | 2010 |
Strong effect of copper(II) coordination on antiproliferative activity of thiosemicarbazone-piperazine and thiosemicarbazone-morpholine hybrids.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Copper; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Morpholines; Organometallic Compounds; Piperazine; Piperazines; Structure-Activity Relationship; Thiosemicarbazones | 2015 |
Ozonation of piperidine, piperazine and morpholine: Kinetics, stoichiometry, product formation and mechanistic considerations.
Topics: Kinetics; Morpholines; Ozone; Pharmaceutical Preparations; Piperazine; Piperazines; Piperidines; Waste Disposal, Fluid; Water Pollutants, Chemical | 2016 |
Click-based synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene-1,2,3-triazoles with piperidine, piperazine, morpholine and thiomorpholine appendages.
Topics: Antitubercular Agents; Cell Survival; Click Chemistry; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Morpholines; Mycobacterium tuberculosis; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Thiophenes; Triazoles | 2016 |
Dual site-controlled two-photon fluorescent probe for the imaging of lysosomal pH in living cells.
Topics: Chloroquine; Fluorescence; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lysosomes; Morpholines; Photons; Piperazine | 2018 |
3-((Hetera)cyclobutyl)azetidines, "Stretched" Analogues of Piperidine, Piperazine, and Morpholine: Advanced Building Blocks for Drug Discovery.
Topics: Azetidines; Cyclization; Drug Discovery; Morpholines; Piperazine; Piperidines | 2019 |
Synthesis of novel morpholine, thiomorpholine and N-substituted piperazine coupled 2-(thiophen-2-yl)dihydroquinolines as potent inhibitors of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Morpholines; Mycobacterium tuberculosis; Piperazine; Quinolines; Structure-Activity Relationship | 2019 |