Page last updated: 2024-09-03

piperaquine and sesquiterpenes

piperaquine has been researched along with sesquiterpenes in 34 studies

Compound Research Comparison

Studies (piperaquine)	Trials (piperaquine)	Recent Studies (post-2010) (piperaquine)	Studies (sesquiterpenes)	Trials (sesquiterpenes)	Recent Studies (post-2010) (sesquiterpenes)
638	227	497	17,489	536	7,668

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.88)	18.7374
1990's	4 (11.76)	18.2507
2000's	27 (79.41)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Cao, DQ; Dong, Y; He, H; Liu, DQ; Liu, RJ; Yang, HL; Yang, PF; Zhang, CY	1
Fu, LC; Guo, XB	1
Li, GD	1
Dong, Y; Liu, D; Liu, R; Yang, H; Yang, P; Zhang, B; Zhang, C	1
Guo, XB	1
Chen, L; Li, G; Lu, Y; Luo, Z	1
Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W	1
Davis, TM; Denis, MB; Fandeur, T; Hewitt, S; Incardona, S; Lim, C; Nimol, K; Poravuth, Y; Socheat, D	1
Chalermrut, K; Krudsood, S; Looareesuwan, S; Pengruksa, C; Silachamroon, U; Srivilairit, S; Treeprasertsuk, S; Wilairatana, P	1
Feng, XP; Liu, DQ	1
Davis, TM; Denis, MB; Hung, TY; Ilett, KF; Karunajeewa, H; Lim, C; Socheat, D	1
Dolecek, C; Dong, TH; Farrar, J; Le, HT; Nguyen, TD; Nguyen, TT; Pham, PM; Stepniewska, K; Tran, TH; Tran, TT; White, NJ	1
Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV	1
Ashley, EA; Brockman, A; Hutagalung, R; Krudsood, S; Leowattana, W; Looareesuwan, S; McGready, R; Nosten, F; Phaiphun, L; Srivilairit, S; White, NJ; Wilairatana, P	1
Diallo, TO; Doui-Doumgba, K; Flori, P; Garraud, O; Gbagba, FE; Nambei, WS; Ndadjimbaye, V; Ndémanga, J; Perraut, R	1
Ashley, EA; Barends, M; Hutagalung, R; Looareesuwan, S; McGready, R; Nosten, F; Phaiphun, L; Proux, S; Slight, T; Thwai, KL; White, NJ	1
Kokwaro, G	1
Chalermrut, K; Kano, S; Krudsood, S; Looareesuwan, S; Pengruksa, C; Phongtananant, S; Silachamroon, U; Srivilairit, S; Tangpukdee, N; Thanachartwet, W; Wilairatana, P	1
Ashton, M; Friberg Hietala, S; Hai, TN; Röshammar, D; Van Huong, N	1
D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; van Geertruyden, JP; van Overmeir, C	1
Duffy, PE; Mutabingwa, TK	1
Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ	1
Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Stepniewska, K; Thongpraseuth, V; White, NJ	1
Arvidsson, B; Ashton, M; Bergquist, J; Bergqvist, Y; Day, NP; Lindegårdh, N; Tarning, J; White, NJ	1
Ashley, EA; Brockman, A; Chan, S; Goubert, L; Janssens, B; Nong, S; Socheat, D; Uong, S; Van Damme, W; van Herp, M	1
Anstey, NM; Ebsworth, EP; Kenangalem, E; Laihad, F; Maristela, R; Price, RN; Ratcliff, A; Siswantoro, H; Tjitra, E; Wuwung, RM	1
Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Maristela, R; Penttinen, PM; Price, RN; Purba, HL; Tjitra, E; Wuwung, RM	1
Adagu, IS; Fivelman, QL; Warhurst, DC	1
Ashley, EA; Day, NP; Myint, HY; Nosten, F; White, NJ	1
Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Lindegardh, N; Penttinen, P; Price, RN; Purba, HL; Ratcliff, A; Siswantoro, H; Tjitra, E	1
Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P	1
Bernasconi, A; Casapia, M; D'Alessandro, U; Delgado, C; Erhart, A; Fanello, C; Gamboa, D; Grande, T; Llanos-Cuentas, A; Torres, K	1
Andrzejewski, C; Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M	1
D'Hoore, W; Kiguba, R; Kirabira, E; Manirakiza, L; Mukonzo, J; Nabirye, L; Ndagije, HB; Olsson, S; Speybroeck, N; Spinewine, A; Sserwanga, A	1

Reviews

1 review(s) available for piperaquine and sesquiterpenes

Article	Year
Efficacy and safety of dihydroartemisinin-piperaquine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:9 Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome	2007

Trials

22 trial(s) available for piperaquine and sesquiterpenes

Article	Year
[Comparative study of artemisinin suppositories and piperaquine phosphate in the treatment of falciparum malaria]. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1989, Volume: 9, Issue:8 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Child; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Suppositories	1989
[Randomised comparison on the treatment of falciparum malaria with dihydroartemisinin and piperaquine]. Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:10 Topics: Adult; Antimalarials; Artemisinins; Drug Evaluation; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes	1993
Efficacy and safety of dihydroartemisinin-piperaquine (Artekin) in Cambodian children and adults with uncomplicated falciparum malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Dec-15, Volume: 35, Issue:12 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome	2002
An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand. The Southeast Asian journal of tropical medicine and public health, 2002, Volume: 33, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinolines; Sesquiterpenes; Thailand; Trimethoprim	2002
Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria. British journal of clinical pharmacology, 2004, Volume: 57, Issue:1 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Blood Glucose; Cambodia; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Electrocardiography; Heart Rate; Hematocrit; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Malaria, Vivax; Middle Aged; Quinolines; Sesquiterpenes	2004
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet (London, England), 2004, Jan-03, Volume: 363, Issue:9402 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Pilot Projects; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam	2004
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam. Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:2 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam	2004
Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand. The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Thailand	2004
Efficacy comparison between anti-malarial drugs in Africans presenting with mild malaria in the Central Republic of Africa: a preliminary study. Parasite (Paris, France), 2005, Volume: 12, Issue:1 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Central African Republic; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Parasitic Sensitivity Tests; Patient Compliance; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Trimethoprim	2005
A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-15, Volume: 41, Issue:4 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes	2005
An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria. The Southeast Asian journal of tropical medicine and public health, 2005, Volume: 36, Issue:5 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Quinolines; Sesquiterpenes; Thailand; Treatment Outcome	2005
Pharmacokinetics of piperaquine after repeated oral administration of the antimalarial combination CV8 in 12 healthy male subjects. European journal of clinical pharmacology, 2006, Volume: 62, Issue:5 Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Drug Combinations; Fasting; Half-Life; Humans; Male; Middle Aged; Pilot Projects; Primaquine; Quinolines; Sesquiterpenes; Trimethoprim	2006
Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:12 Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Female; Humans; Leukocyte Count; Malaria, Falciparum; Male; Quinolines; Rwanda; Sesquiterpenes; Treatment Outcome	2006
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison. Lancet (London, England), 2006, 06-24, Volume: 367, Issue:9528 Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome	2006
An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos). Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:8 Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Female; Humans; Laos; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Quinolines; Recurrence; Sesquiterpenes; Treatment Failure; Treatment Outcome	2006
Characterization of human urinary metabolites of the antimalarial piperaquine. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:12 Topics: Antimalarials; Artemisinins; Chromatography, Liquid; Drug Combinations; Humans; Magnetic Resonance Spectroscopy; Male; Quinolines; Sesquiterpenes; Tandem Mass Spectrometry	2006
A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia. Tropical medicine & international health : TM & IH, 2007, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aged; Anemia; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Genome, Protozoan; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome	2007
Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison. Lancet (London, England), 2007, Mar-03, Volume: 369, Issue:9563 Topics: Adolescent; Adult; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Ethanolamines; Female; Fluorenes; Humans; Indonesia; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Prospective Studies; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome; Urticaria; Vomiting	2007
Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Apr-15, Volume: 44, Issue:8 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Tolerance; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome	2007
Clinical and pharmacological determinants of the therapeutic response to dihydroartemisinin-piperaquine for drug-resistant malaria. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Indonesia; Infant; Malaria; Male; Middle Aged; Prospective Studies; Quinolines; Sesquiterpenes; Survival Analysis; Treatment Outcome	2007
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome	2008
A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru. PloS one, 2007, Oct-31, Volume: 2, Issue:10 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Peru; Quinolines; Sesquiterpenes	2007

Other Studies

11 other study(ies) available for piperaquine and sesquiterpenes

Article	Year
[Sensitivity in vitro of Plasmodium falciparum to chloroquine, pyronaridine, artesunate and piperaquine in south Yunnan]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1992, Volume: 10, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1992
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:6 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes	1985
[Sensitivity of Plasmodium falciparum to seven antimalarials in China-Laos border]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1995, Volume: 13, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1995
Histopathological changes of Macaca mulatta infected with Plasmodium knowlesi. Chinese medical journal, 2001, Volume: 114, Issue:10 Topics: Animals; Artemisinins; Artesunate; Macaca mulatta; Malaria; Monkey Diseases; Plasmodium knowlesi; Quinolines; Sesquiterpenes; Suppositories	2001
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1998, Volume: 16, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1998
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes	2003
Once-daily combination therapy for uncomplicated malaria: is this the way forward? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-15, Volume: 41, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Sesquiterpenes	2005
Artemisinin combination therapies. Lancet (London, England), 2006, Jun-24, Volume: 367, Issue:9528 Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child, Preschool; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Quinolines; Sesquiterpenes	2006
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Antagonism; Drug Combinations; Drug Interactions; Drug Resistance; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes; Tritium	2007
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Humans; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Sesquiterpenes; Treatment Outcome	2008
Healthcare professionals' perspective can guide post-marketing surveillance of artemisinin-based combination therapy in Uganda. Malaria journal, 2020, Feb-10, Volume: 19, Issue:1 Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Female; Health Personnel; Humans; Logistic Models; Malaria; Male; Patient Compliance; Plasmodium falciparum; Product Surveillance, Postmarketing; Quinolines; Sesquiterpenes; Surveys and Questionnaires; Tablets; Treatment Failure; Uganda	2020