piperaquine has been researched along with pyrimethamine in 51 studies
| Studies (piperaquine) | Trials (piperaquine) | Recent Studies (post-2010) (piperaquine) | Studies (pyrimethamine) | Trials (pyrimethamine) | Recent Studies (post-2010) (pyrimethamine) |
|---|---|---|---|---|---|
| 638 | 227 | 497 | 5,088 | 738 | 1,047 |
| Protein | Taxonomy | piperaquine (IC50) | pyrimethamine (IC50) |
|---|---|---|---|
| Dihydrofolate reductase | Homo sapiens (human) | 3.1057 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.1007 | |
| Beta-hexosaminidase subunit alpha | Homo sapiens (human) | 6.8333 | |
| Beta-hexosaminidase subunit beta | Homo sapiens (human) | 6.4 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 4.3 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.0609 | |
| Dihydrofolate reductase | Pneumocystis carinii | 3.25 | |
| Dihydrofolate reductase | Candida albicans | 5 | |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | 15.615 | |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | 0.39 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.3217 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum 3D7 | 2.48 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 2.0727 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (15.69) | 29.6817 |
| 2010's | 31 (60.78) | 24.3611 |
| 2020's | 12 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Biamonte, MA; Le Roch, KG; Wanner, J | 1 |
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Diallo, TO; Doui-Doumgba, K; Flori, P; Garraud, O; Gbagba, FE; Nambei, WS; Ndadjimbaye, V; Ndémanga, J; Perraut, R | 1 |
| Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S | 1 |
| Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P | 1 |
| Dokomajilar, C; Dorsey, G; Ouédraogo, JB; Rosenthal, PJ; Rouamba, N; Séré, Y; Zongo, I | 1 |
| Davis, TM; Gomorrai, PS; Griffin, S; Ilett, KF; Karunajeewa, HA; Kotab, K; Lautu, D; Law, I; Lin, E; Mueller, I; Oa, O; Page-Sharp, M; Salman, S; Senn, M; Siba, P; Suano, P; Tarongka, N; Ura, A; Wong, R | 1 |
| Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B | 1 |
| Cairns, M; Cames, C; Cheng, Y; Cisse, B; Faye, B; Faye, E; Faye, O; Gaye, O; Greenwood, B; Lô, AC; Milligan, P; NDiaye, JL; NDiaye, M; NDiaye, O; Simondon, K; Trape, JF | 1 |
| Dokomajilar, C; Greenhouse, B; Ouédraogo, JB; Rosenthal, PJ; Rouamba, N; Séré, YY; Somé, AF; Zongo, I | 1 |
| Doua, JY; Lutumba, P; Matangila, J; Van Geertruyden, JP | 1 |
| Gogtay, N; Kannan, S; Olliaro, PL; Sinclair, D; Thatte, UM | 1 |
| Achan, J; Aweeka, FT; Bigira, V; Clark, TD; Dorsey, G; Havlir, DV; Huang, L; Kamya, MR; Kapisi, J; Kinara, S; Muhindo, MK; Mwangwa, F; Osterbauer, B; Rosenthal, PJ | 1 |
| Achan, J; Aweeka, FT; Bigira, V; Clark, TD; Dorsey, G; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Kapisi, J; Kinara, S; Muhindo, MK; Mwangwa, F; Rosenthal, PJ | 1 |
| Compaore, YD; Greenwood, B; Milligan, P; Nosten, F; Ouedraogo, JB; Rosenthal, PJ; Some, AF; Sutherland, C; Tarning, J; Zongo, I | 1 |
| Batty, KT; Benjamin, JM; Davis, TM; Lorry, L; Moore, BR; Mueller, I; Page-Sharp, M; Robinson, LJ; Salman, S; Siba, PM; Tawat, S; Yadi, G | 1 |
| Desai, M; Gutman, J; Juma, E; Kariuki, S; Katana, A; L'lanziva, A; Laserson, K; Otieno, K; Ouma, P; ter Kuile, FO; Were, V; Williamson, J | 1 |
| Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H | 1 |
| Auma, A; Bigira, V; Bowen, K; Boyle, MJ; Dorsey, G; Farrington, LA; Feeney, ME; Jagannathan, P; Kamya, MR; Kapisi, J; McIntyre, TI; Nalubega, M; Naluwu, K; Nankya, F; Sikyomu, E; Vance, HM; Wamala, S | 1 |
| Ategeka, J; Awori, P; Charlebois, ED; Clark, TD; Dorsey, G; Feeney, ME; Havlir, DV; Jagannathan, P; Kakuru, A; Kamya, MR; Muehlenbachs, A; Muhindo, MK; Nakalembe, M; Natureeba, P; Nayebare, P; Olwoch, P; Opira, B; Rizzuto, G | 1 |
| Bass, JK; Bigira, V; Boivin, MJ; Dorsey, G; Familiar-Lopez, I; Kamya, M; Kapisi, J; Muhindo, M; Nakasujja, N; Opoka, RO; Ruiseñor-Escudero, H; Sikorskii, A | 1 |
| Ali, D; Faragher, B; Kalilani, L; Kang'ombe, A; Khairallah, C; Levitt, B; Madanitsa, M; Meshnick, S; Mwapasa, V; Pace, C; Smedley, J; Taylor, SM; Ter Kuile, FO; Thwai, KL; van Eijk, AM; Wang, D | 1 |
| Dorsey, G; Gutman, J; Kovacs, S; Stergachis, A; Ter Kuile, FO | 1 |
| Rogerson, SJ; Unger, HW | 1 |
| Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ | 1 |
| da Luz, RI; Doua, JY; Lutumba, P; Matangila, JR; Mitashi, P; Van Geertruyden, JP | 1 |
| Abdel Hamid, MM; Adam, MA; Elkando, NS; Elnour, FAA; Malik, EM; Mohamed, AO; Mohamed, OS; Suliman, A | 1 |
| Affara, M; Bei, AK; Deme, AB; Dieye, B; Diongue, K; Gaye, A; Koita, O; Krogstad, DJ; Mbaye, A; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Ndiaye, YD; Nwakanma, D; Sy, M; Sy, N; Volkman, S; Yade, MS | 1 |
| Clark, RL | 1 |
| Aweeka, F; Conrad, MD; Dorsey, G; Foster, M; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Legac, J; Mota, D; Nayebare, P; Rosenthal, PJ; Tukwasibwe, S; Tumwebaze, P; Wallender, E; Whalen, M | 1 |
| Bousema, T; Bradley, J; Brown, JM; Chen, I; Diarra, K; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Hwang, J; Issiaka, D; Keita, S; Kone, DT; Lanke, K; Mahamar, A; McCulloch, C; Müller, O; Roh, ME; Sanogo, K; Soumare, HM; Srinivasan, V; Stone, WJR; Traore, SF | 1 |
| Aweeka, F; Beeson, J; Charlebois, ED; Clark, TD; Dorsey, G; Drakeley, C; Feeney, ME; Greenhouse, B; Havlir, DV; Jagannathan, P; Kakuru, A; Kamya, MR; Muhindo, MK; Nakalembe, M; Nankya, F; Natureeba, P; Okiring, J; Olwoch, P; Opira, B; Prahl, M; Reiling, L; Rodriguez-Barraquer, I; Ssewanyana, I; Tetteh, K; Wallender, E | 1 |
| Boxberger, M; Gaillard, T; Madamet, M; Pradines, B | 1 |
| Ategeka, J; Clark, TD; Dorsey, G; Havlir, DV; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Nakalembe, M; Nayebare, P; Ochieng, T; Ochokoru, H; Opira, B; Ruel, T | 1 |
| Laufer, MK | 1 |
| Esu, E; Meremikwu, M; Oduwole, O; Okusanya, BO; Olaleye, A | 1 |
| Buffet, C; Karahalios, A; Khairallah, C; Kuile, FOT; Madanitsa, M; Mwapasa, V; Narum, DL; Phiri, LK; Randall, LM; Rogerson, SJ; Teo, A | 1 |
| Benjamin, JM; Davis, TME; Kasian, B; Kong, C; Laman, M; Moore, BR; Mueller, I; Ome-Kaius, M; Robinson, LJ; Rogerson, S; Tobe, R; Yadi, G | 1 |
| Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J | 1 |
| Ategeka, J; Chandramohan, D; Clark, TD; Dorsey, G; Havlir, DV; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Nakalembe, M; Ochieng, T; Ochokoru, H; Roh, ME; Ruel, T; Staedke, SG | 1 |
| Bousema, T; Chen, I; Diarra, K; Diawara, H; Dicko, A; Drakeley, C; Gosling, R; Graumans, W; Lanke, K; Mahamar, A; Niambele, SM; Roh, ME; Sanogo, K | 1 |
| Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E | 1 |
| Andronescu, LR; Chinkhumba, J; Gutman, JR; Kachepa, W; Kachingwe, M; Laufer, MK; Liang, Y; Mathanga, DP; Peterson, I; Sharma, A | 1 |
| Esu, EB; Meremikwu, MM; Oringanje, C | 1 |
| Champo, D; Chongwe, G; Ippolito, MM; Kabuya, JB; Manyando, C; Mulenga, M; Mwakazanga, D; Sikalima, J; Tende, C; Young, AMP | 1 |
| Clapp, S; Freedman, B; Green, CL; Kirui, JK; Korwa, S; Njuguna, FM; O'Meara, WP; Taylor, SM; Wu, A | 1 |
| Akinola, O; Amusan, AI; Ategbero, E; Gbotosho, GO | 1 |
| Alifrangis, M; Ashorn, U; Barsosio, HC; Chico, RM; Dodd, J; Gesase, S; Gutman, JR; Hansson, H; Hill, J; Kariuki, S; Kavishe, RA; Klein, N; Lusingu, JPA; Madanitsa, M; Magnussen, P; Maleta, K; Minja, DTR; Mosha, JF; Msemo, OA; Mtove, G; Mukerebe, C; Mwapasa, V; Onyango, ED; Otieno, K; Phiri, KS; Saidi, Q; Schmiegelow, C; Ter Kuile, FO; Wang, D | 1 |
| Abebe, A; Ahmedin, M; Atim, MG; Embaye, SM; Kahabuka, M; Kazembe, D; Manyazewal, T; Mesfin, T; Muthoka, EN; Namuganza, S; Usmael, K | 1 |
14 review(s) available for piperaquine and pyrimethamine
| Article | Year |
|---|---|
Recent advances in malaria drug discovery.
Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure | 2013 |
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria, Vivax; Parasitemia; Primaquine; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Secondary Prevention; Sulfadoxine | 2013 |
Safety, tolerability, and efficacy of repeated doses of dihydroartemisinin-piperaquine for prevention and treatment of malaria: a systematic review and meta-analysis.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2017 |
Prevention and control of malaria in pregnancy - new threats, new opportunities?
Topics: Adult; Animals; Antimalarials; Artemisinins; Culicidae; Drug Combinations; Drug Resistance; Female; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications, Parasitic; Primary Prevention; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
A systematic review and meta-analysis of dihydroartemisinin-piperaquine versus sulphadoxine-pyrimethamine for malaria prevention in pregnancy.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Parasitemia; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2019 |
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 2020 |
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Global Health; HIV Infections; Humans; Malaria; Malnutrition; Mefloquine; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Vulnerable Populations | 2021 |
Intermittent preventive treatment for malaria in infants.
Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Bias; Confidence Intervals; Disease Eradication; Drug Combinations; Endemic Diseases; Hospitalization; Humans; Infant; Malaria; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2021 |
Safety and tolerability of repeated doses of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a systematic review and an aggregated data meta-analysis of randomized controlled trials.
Topics: Antimalarials; Drug Combinations; Female; Humans; Infant; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Vomiting | 2023 |
27 trial(s) available for piperaquine and pyrimethamine
| Article | Year |
|---|---|
Efficacy comparison between anti-malarial drugs in Africans presenting with mild malaria in the Central Republic of Africa: a preliminary study.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Central African Republic; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Parasitic Sensitivity Tests; Patient Compliance; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Trimethoprim | 2005 |
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2008 |
Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso.
Topics: Amodiaquine; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Faso; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine | 2007 |
A trial of combination antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kaplan-Meier Estimate; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Proportional Hazards Models; Pyrimethamine; Quinolines; Recurrence; Sulfadoxine | 2008 |
Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cluster Analysis; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Male; Pyrimethamine; Quinolines; Rural Population; Senegal; Sulfadoxine; Treatment Outcome | 2009 |
Intermittent preventive treatment: efficacy and safety of sulfadoxine-pyrimethamine and sulfadoxine-pyrimethamine plus piperaquine regimens in schoolchildren of the Democratic Republic of Congo: a study protocol for a randomized controlled trial.
Topics: Antimalarials; Child; Clinical Protocols; Congo; Drug Combinations; Drug Therapy, Combination; Ethics, Medical; Humans; Malaria; Pyrimethamine; Quinolines; Research Design; Sample Size; Sulfadoxine | 2013 |
Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial.
Topics: Antimalarials; Artemisinins; Cohort Studies; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Male; Pyrimethamine; Quinolines; Sulfadoxine; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2014 |
Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial.
Topics: Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Cohort Studies; Drug Combinations; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Quinolines; Sulfadoxine; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2014 |
Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Case-Control Studies; Chemoprevention; Child, Preschool; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Quinolines; Seasons; Sulfadoxine | 2015 |
Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin-piperaquine versus intermittent preventive treatment with sulfadoxine-pyrimethamine for the control of malaria during pregnancy in western Kenya: an open-lab
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Female; Humans; Kenya; Malaria; Mass Screening; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Diagnosis; Pyrimethamine; Quinolines; Risk Factors; Sulfadoxine; Treatment Outcome; Young Adult | 2015 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.
Topics: Artemisinins; Child, Preschool; Drug Combinations; GPI-Linked Proteins; Humans; Immune Tolerance; Infant; Longitudinal Studies; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinolines; Receptors, Antigen, T-Cell, gamma-delta; Receptors, IgG; Sulfadoxine; T-Lymphocyte Subsets; Up-Regulation | 2016 |
Dihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Humans; Incidence; Malaria; Parasitemia; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Uganda; Vomiting; Young Adult | 2016 |
Malaria illness mediated by anaemia lessens cognitive development in younger Ugandan children.
Topics: Age Factors; Anemia; Antimalarials; Artemisinins; Child, Preschool; Cognition; Cognition Disorders; Coinfection; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Quinolines; Risk Factors; Sulfadoxine; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2016 |
Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Tr
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Diagnostic Tests, Routine; Drug Combinations; Female; Humans; Malaria; Malawi; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2016 |
Efficacy and safety of intermittent preventive treatment in schoolchildren with sulfadoxine/pyrimethamine (SP) and SP plus piperaquine in Democratic Republic of the Congo: a randomised controlled trial.
Topics: Adolescent; Anemia; Antimalarials; Chemoprevention; Child; Child, Preschool; Democratic Republic of the Congo; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Hemoglobins; Humans; Malaria; Male; Parasitemia; Pyrimethamine; Quinolines; Schools; Students; Sulfadoxine; Treatment Outcome | 2017 |
Efficacies of DHA-PPQ and AS/SP in patients with uncomplicated Plasmodium falciparum malaria in an area of an unstable seasonal transmission in Sudan.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Quinolines; Sudan; Sulfadoxine; Time Factors; Treatment Outcome; Young Adult | 2017 |
Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.
Topics: Adolescent; Adult; Amodiaquine; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Malaria, Falciparum; Mali; Methylene Blue; Middle Aged; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2018 |
Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Time Factors; Treatment Outcome; Uganda; Young Adult | 2018 |
Monthly sulfadoxine-pyrimethamine versus dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a double-blind, randomised, controlled, superiority trial.
Topics: Adult; Antimalarials; Artemisinins; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Uganda; Young Adult | 2019 |
Intermittent screening and treatment with dihydroartemisinin-piperaquine and intermittent preventive therapy with sulfadoxine-pyrimethamine have similar effects on malaria antibody in pregnant Malawian women.
Topics: Adolescent; Adult; Antibodies, Protozoan; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria, Falciparum; Malawi; Mass Screening; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2019 |
A Randomized Open-Label Evaluation of the Antimalarial Prophylactic Efficacy of Azithromycin-Piperaquine versus Sulfadoxine-Pyrimethamine in Pregnant Papua New Guinean Women.
Topics: Adult; Antimalarials; Asymptomatic Diseases; Azithromycin; Chemoprevention; Drug Combinations; Erythrocytes; Female; Gestational Age; Humans; Live Birth; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Parasitemia; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pyrimethamine; Quinolines; Random Allocation; Severity of Illness Index; Stillbirth; Sulfadoxine | 2019 |
Infant sex modifies associations between placental malaria and risk of malaria in infancy.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Placenta Diseases; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2020 |
The Effect of Intermittent Preventive Treatment of Malaria During Pregnancy and Placental Malaria on Infant Risk of Malaria.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Infant; Malaria; Malawi; Parasitemia; Piperazines; Placenta; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Treatment Outcome | 2022 |
Safety and efficacy of intermittent presumptive treatment with sulfadoxine-pyrimethamine using rapid diagnostic test screening and treatment with dihydroartemisinin-piperaquine at the first antenatal care visit (IPTp-SP+): study protocol for a randomized
Topics: Antimalarials; Artemisinins; Clinical Trials, Phase III as Topic; Diagnostic Tests, Routine; Drug Combinations; Female; HIV Infections; Humans; Infant; Placenta; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Retrospective Studies; Sulfadoxine | 2021 |
Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial.
Topics: Amodiaquine; Anemia, Sickle Cell; Antimalarials; Artemisinins; Chemoprevention; Child; Child, Preschool; Drug Combinations; Female; Humans; Hydroxyurea; Infant; Kenya; Malaria; Malaria, Falciparum; Male; Proguanil; Pyrimethamine; Sulfadoxine | 2022 |
Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled tr
Topics: Adult; Antimalarials; Azithromycin; Drug Combinations; Female; Humans; Infant, Newborn; Kenya; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Tanzania; Young Adult | 2023 |
10 other study(ies) available for piperaquine and pyrimethamine
| Article | Year |
|---|---|
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Peroxides; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinolines; Spiro Compounds | 2007 |
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Burkina Faso; Drug Combinations; Drug Resistance, Bacterial; Ethanolamines; Fluorenes; Genotype; Humans; Infant; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Recurrence; Sulfadoxine | 2010 |
Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Biological Availability; Dietary Fats; Drug Combinations; Female; Follow-Up Studies; Food-Drug Interactions; Humans; Infant, Newborn; Malaria, Falciparum; Models, Statistical; Papua New Guinea; Pregnancy; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2015 |
Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genotype; Genotyping Techniques; Humans; Indoles; Inhibitory Concentration 50; Malaria; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Quinolines; Senegal; Young Adult | 2017 |
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Has doxycycline, in combination with anti-malarial drugs, a role to play in intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa?
Topics: Africa; Antimalarials; Artemisinins; Doxycycline; Drug Combinations; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnant Women; Pyrimethamine; Quinolines; Sulfadoxine | 2018 |
Beyond birthweight: benefits and risks of preventing malaria in pregnancy.
Topics: Artemisinins; Double-Blind Method; Drug Combinations; Female; Humans; Malaria; Pregnancy; Pyrimethamine; Quinolines; Risk Assessment; Sulfadoxine | 2019 |
Persistence of mRNA indicative of Plasmodium falciparum ring-stage parasites 42 days after artemisinin and non-artemisinin combination therapy in naturally infected Malians.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Drug Combinations; Humans; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinolines; RNA, Messenger; RNA, Protozoan; Sulfadoxine; Time Factors; Young Adult | 2021 |
Comparative efficacy of sulphadoxine-pyrimethamine and dihydroartemisinin-piperaquine against malaria infection during late-stage pregnancy in mice.
Topics: Animals; Antimalarials; Drug Combinations; Drug Therapy, Combination; Female; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Pregnancy; Pyrimethamine | 2023 |