Page last updated: 2024-09-03

piperaquine and oz 439

piperaquine has been researched along with oz 439 in 8 studies

Compound Research Comparison

Studies (piperaquine)	Trials (piperaquine)	Recent Studies (post-2010) (piperaquine)	Studies (oz 439)	Trials (oz 439)	Recent Studies (post-2010) (oz 439)
638	227	497	46	9	46

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	7 (87.50)	24.3611
2020's	1 (12.50)	2.80

Authors

Authors	Studies
Biamonte, MA; Le Roch, KG; Wanner, J	1
Fidock, DA; Flannery, EL; Winzeler, EA	1
Ashton, TD; Burrows, JN; Charman, SA; Creek, DJ; Devine, SM; Laleu, B; Möhrle, JJ; Sleebs, BE	1
Anstey, NM; Chalfein, F; Haynes, RK; Kenangalem, E; Marfurt, J; Möhrle, JJ; Piera, KA; Prayoga, P; Price, RN; Sebayang, B; Wabiser, F; Wirjanata, G; Wittlin, S	1
Darpo, B; Duparc, S; Ferber, G; Laurijssens, B; Macintyre, F; Siegl, P; Toovey, S	1
Adams, M; Bousema, T; Chalon, S; Collins, KA; Elliott, S; McCarthy, JS; Mitchell, H; Möhrle, JJ; Rampton, M; Reuling, IJ; Sauerwein, R; Wang, CY	1
Adoke, Y; Barry, A; Dossou, Y; Duong, TT; Khim, N; Klopper, R; Laurijssens, B; Legrand, E; Leroy, D; Macintyre, F; Ménard, D; Mombo-Ngoma, G; Ndong Ngomo, JM; Ouoba, S; Phuc, BQ; Tshefu, AK; Varo, R	1
Akakpo, S; Chalon, S; Chughlay, MF; Csermak-Renner, K; Djeriou, E; Gaur, AH; Leboulleux, D; McCarthy, J; Odedra, A; Shanks, GD; Winnips, C	1

Reviews

3 review(s) available for piperaquine and oz 439

Article	Year
Recent advances in malaria drug discovery. Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10 Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure	2013
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
The Development Process for Discovery and Clinical Advancement of Modern Antimalarials. Journal of medicinal chemistry, 2019, 12-12, Volume: 62, Issue:23 Topics: Antimalarials; Drug Discovery; Humans; Malaria; Molecular Structure; Plasmodium	2019

Trials

3 trial(s) available for piperaquine and oz 439

Article	Year
Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria. British journal of clinical pharmacology, 2015, Volume: 80, Issue:4 Topics: Adamantane; Adolescent; Adult; Antimalarials; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Healthy Volunteers; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Peroxides; Quinolines; Young Adult	2015
A controlled human malaria infection model enabling evaluation of transmission-blocking interventions. The Journal of clinical investigation, 2018, 04-02, Volume: 128, Issue:4 Topics: Adamantane; Adolescent; Adult; Animals; Antimalarials; Culicidae; Erythrocytes; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Peroxides; Plasmodium falciparum; Primaquine; Quinolines	2018
African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker. Malaria journal, 2019, Apr-10, Volume: 18, Issue:1 Topics: Adamantane; Adolescent; Adult; Africa; Aged; Antimalarials; Aspartic Acid Endopeptidases; Biomarkers; Child; Child, Preschool; DNA Copy Number Variations; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Peroxides; Plasmodium falciparum; Protozoan Proteins; Quinolines; Vietnam; Young Adult	2019

Other Studies

2 other study(ies) available for piperaquine and oz 439

Article	Year
Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:10 Topics: Adamantane; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Heterocyclic Compounds, 1-Ring; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Plasmodium vivax; Quinolines; Spiro Compounds	2012
Liver Enzyme Elevations in The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1 Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult	2020

Article

Year

Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax.

Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:10

Topics: Adamantane; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Heterocyclic Compounds, 1-Ring; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Plasmodium vivax; Quinolines; Spiro Compounds

2012

Liver Enzyme Elevations in

The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1

Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult

2020