piperaquine has been researched along with artemisinin in 60 studies
| Studies (piperaquine) | Trials (piperaquine) | Recent Studies (post-2010) (piperaquine) | Studies (artemisinin) | Trials (artemisinin) | Recent Studies (post-2010) (artemisinin) |
|---|---|---|---|---|---|
| 638 | 227 | 497 | 2,825 | 132 | 1,682 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (10.00) | 29.6817 |
| 2010's | 42 (70.00) | 24.3611 |
| 2020's | 10 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Fu, LC; Guo, XB | 1 |
| Li, GD | 1 |
| Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ | 1 |
| Lindegardh, N; Tarning, J | 1 |
| Brittenham, GM; Kano, S; Krudsood, S; Li, G; Looareesuwan, S; Pengruksa, C; Phophak, N; Tangpukdee, N; Thanachartwet, V; Wilairatana, P | 1 |
| Brittenham, GM; Guoqiao, L; Jianping, S; Krudsood, S; Looareesuwan, S; Pothipak, N; Srivilairit, S; Tangpukdee, N; Thanchatwet, V; Wilairatana, P | 1 |
| Song, JP; Tan, B; Trung, TN; Van Phuc, D | 1 |
| Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B | 1 |
| Dara, P; Deng, C; Jian, H; Li, G; Ou, F; Seila, S; Socheat, D; Sokunthea, S; Song, J; Tan, B | 1 |
| Arinaitwe, E; Bigira, V; Dorsey, G; Kakuru, A; Kamya, M; Sandison, T; Tappero, JW; Verret, WJ; Wanzira, H | 1 |
| Chavchich, M; Dai, B; Edstein, MD; Phong, NC; Quang, HH; Shanks, GD; Thanh, NX; Trung, TN | 1 |
| Ariey, F; Beck, HP; Csajka, C; Decosterd, LA; Duong, S; Genton, B; Guidi, M; Kabanywanyi, AM; Olliaro, P; Staehli Hodel, EM | 1 |
| Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW | 1 |
| Abiola, A; Faye, B; Folly, K; Gaye, O; Lo, AC; Ndiaye, JL; Ndiaye, LA; Ndiaye, M; Sow, D; Sylla, K; Tine, RC | 1 |
| Chen, K; Cui, L; Fan, Q; Feng, G; Hao, M; Lin, Y; Sun, L; Wu, Y; Yang, Z; Zhao, Z | 1 |
| Achan, J; Arinaitwe, E; Charlebois, E; Clark, TD; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, MR; Muhindo, MK; Mwangwa, F; Rosenthal, PJ; Ruel, T; Tappero, JW | 1 |
| Li, X; Xing, J; Yang, A; Zang, M; Zhu, F | 1 |
| Lindegardh, N; Nosten, F; Ouédraogo, JB; Parikh, S; Rosenthal, PJ; Rouamba, N; Somda, SA; Somé, FA; Tarning, J; Zongo, I | 1 |
| Dahlstrom, S; Ferreira, PE; Franzén, O; Gil, JP; Lum, JK; Nosten, F; Osório, NS; Veiga, MI | 1 |
| Baker, M; Bousema, T; Cairns, M; D'Alessandro, U; Ferguson, NM; Ghani, AC; Griffin, JT; Hugo, P; Jagoe, G; Okell, LC; Tarning, J; Ubben, D | 1 |
| Buathong, N; Chanarat, N; Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Heng, TK; Jacob, C; Kong, N; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Plowe, C; Prom, S; Saingam, P; Saunders, DL; Se, Y; Sea, D; Sriwichai, S; Sundrakes, S; Takala-Harrison, S; Tangthongchaiwiriya, K; Teja-Isavadharm, P; Tyner, SD; Yingyuen, K; Yom, Y | 1 |
| Bouth, DM; Char, MC; Domergue, A; Duru, V; Khim, N; Kim, S; Leang, R; Menard, D; Ringwald, P; Song, L; Tarning, J; Taylor, WR; Witkowski, B | 1 |
| Brashear, A; Cabrera, M; Cui, L; Gupta, B; Hu, Y; Kemirembe, K; Li, X; Liang, X; Miao, J; Shrestha, S; Sun, X; Wang, Y; Wang, Z; Wu, Y; Yang, Z; Zhang, Y | 1 |
| d'Alessandro, U; Dahal, P; Dorsey, G; Guerin, PJ; Nsanzabana, C; Price, RN; Sibley, CH; Stepniewska, K; Talisuna, AO | 1 |
| Baird, JK; Boni, MF; Dondorp, AM; Farrar, J; Lam, HM; Nguyen, TD; Olliaro, P; Thwaites, GE; White, NJ | 1 |
| Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H | 1 |
| Maxmen, A | 1 |
| Aderoyeje, T; Adewoye, EO; Akano, K; Ayede, AI; Fatunmbi, B; Ntadom, G; Sowunmi, A | 1 |
| De Smet, M; Dondorp, A; Etienne, W; Falq, G; Imwong, M; Kindermans, JM; Nguon, C; Rekol, H; Van Den Bergh, R | 1 |
| Bouhired, S; Duparc, S; Goyal, N; Green, JA; Hussaini, A; Jones, SW; Koh, GC; Kostov, I; Mohamed, K; Taylor, M; Wolstenholm, A | 1 |
| Rogerson, SJ; Unger, HW | 1 |
| Leroy, D | 1 |
| Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ | 1 |
| Khositnithikul, R; Mungthin, M; Sitthichot, N; Suwandittakul, N; Ward, SA; Watanatanasup, E | 1 |
| Combrinck, JM; Cooper, RA; Cowell, AN; Dhingra, SK; Egan, TJ; Fidock, DA; Gupta, P; Henrich, PP; Hoke, JM; Mok, S; Okombo, J; Redhi, D; Stegman, ML; Winzeler, E; Yeo, T | 1 |
| Nosten, F | 1 |
| Clark, RL | 1 |
| Bailey, JA; Barnett, EJ; Brazeau, NF; Chaorattanakawee, S; Gosi, P; Juliano, JJ; Lanteri, CA; Lin, JT; Lon, C; Meshnick, SR; Norris, LD; Parobek, CM; Parr, JB; Saunders, DL; Spring, MD | 1 |
| Aweeka, F; Conrad, MD; Dorsey, G; Foster, M; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Legac, J; Mota, D; Nayebare, P; Rosenthal, PJ; Tukwasibwe, S; Tumwebaze, P; Wallender, E; Whalen, M | 1 |
| Roberts, L | 1 |
| Adegnika, AA; Cattaneo, C; Duparc, S; Endamne, L; Flohr, L; Groger, M; Hutchinson, D; Kabwende, L; Kim, J; Kremsner, PG; Lell, B; Lötsch, F; Mischlinger, J; Moehrle, J; Mombo-Ngoma, G; Mordmüller, B; Nguyen, TT; Ramharter, M; Remppis, J; Sievers, M; Velavan, TP; Veletzky, L; Zoleko Manego, R | 1 |
| Anh, CX; Birrell, GW; Chavchich, M; Edstein, MD; Quang, NN; Rowcliffe, K; Travers, T; van Breda, K | 1 |
| Bacar, A; Deng, C; Fay, MP; Feng, D; Huang, B; Huang, S; Kéké, RA; Li, D; Li, G; Li, XB; Lin, L; Liu, XH; Lu, F; Mohadji, F; Mohamed, M; Msa Mliva, A; Oithik, F; Said Abdallah, K; Song, J; Su, XZ; Tuo, F; Wang, Q; Wang, X; Wellems, TE; Wu, W; Wu, Z; Xu, Q; Xue, L; Yan, H; Yang, T; Zhang, H; Zheng, S; Zhou, J | 1 |
| Kamara, ARY; Menard, D; Sahr, F; Samai, M; Smith, SJ; Swaray, AS; Warsame, M | 1 |
| Cao, P; Dini, S; Fowkes, FJI; McCaw, JM; Price, RN; Simpson, JA; van der Pluijm, RW; Zaloumis, S | 1 |
| Asua, V; Conrad, MD; Dorsey, G; Kamya, MR; Kigozi, SP; Legac, J; Nsobya, SL; Rosenthal, PJ; Vinden, J | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Deng, C; Huang, B; Liang, Y; Song, J; Su, Y; Tan, B; Wang, Q; Wu, G; Wu, W; Zhang, H; Zhang, Z; Zhou, C | 1 |
| Chy, S; Felger, I; Hastings, I; Hodel, EM; Jones, S; Kay, K; Mbituyumuremyi, A; Menard, D; Uwimana, A | 1 |
| Li, X; Ru, L; Song, J; Wang, Q; Xu, Q; Xu, Z; Yuan, Y; Yuan, Z; Zhang, S | 1 |
| D'Hoore, W; Kiguba, R; Kirabira, E; Manirakiza, L; Mukonzo, J; Nabirye, L; Ndagije, HB; Olsson, S; Speybroeck, N; Spinewine, A; Sserwanga, A | 1 |
| Amaratunga, C; Amato, R; Anvikar, AR; Ashley, E; Baidya, S; Behera, PK; Callery, JJ; Chau, NH; Cheah, PY; Chotivanich, K; Chutasmit, K; Day, NPJ; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, A; Fanello, C; Gantait, K; Ghosh, T; Gonçalves, S; Grobusch, MP; Hanboonkunupakarn, B; Heaton, J; Hien, TT; Hlaing, TM; Hoa, NT; Hoglund, RM; Huy, R; Imwong, M; Jacob, CG; Jittamala, P; Kaewmok, W; Kwiatkowski, DP; Lek, D; Lin, K; Mao, S; Maude, RJ; Mayxay, M; Miotto, O; Mohanty, AK; Mukaka, M; Newton, PN; Onyamboko, M; Oun, S; Pearson, RD; Peto, TJ; Pukrittayakamee, S; Pyae Phyo, A; Runcharern, R; Saelow, C; Satpathi, P; Satpathi, S; Smithuis, F; Sovann, Y; Sreng, S; Suon, S; Tarning, J; Thanh, NV; Thant, M; Thuy-Nhien, NT; Tripura, A; Tripura, R; Ul Islam, A; Valecha, N; van der Pluijm, RW; van Vugt, M; von Seidlein, L; Waithira, N; White, NJ; Winterberg, M; Woodrow, CJ; Yen, S | 1 |
| Deng, C; Guan, X; Guo, J; Jin, C; Li, G; Li, H; Song, J; Tang, Y; Wang, Q; Xie, F; Xu, Q; Yu, W; Yuan, M; Yuan, Y; Zhang, H; Zou, Y | 1 |
| Ashley, EA; Aung, H; Aung, Y; Day, NPJ; Dondorp, AM; Heaton, J; Hlaing, T; Imwong, M; Indrasuta, C; Khant, ZS; Kyaw, TT; Maung, SM; McLean, ARD; Phyo, AK; Smithuis, FM; Soe, K; Swe, MMM; Tun, KM; Tun, NN; von Seidlein, L; White, NJ | 1 |
| Liu, Z; Xie, Y; Xing, J; Zhang, L; Zhang, Y | 1 |
| Abdallah, KS; Bacar, A; Deng, C; Li, G; Li, M; Liu, R; Lu, C; Silai, R; Song, J; Tan, R; Wu, W; Xu, Q; Yuan, Y; Zhang, H; Zheng, S | 1 |
| Chen, Y; Deng, C; Li, G; Li, X; Ru, L; Song, J; Xu, Q; Xu, Z; Yuan, Y; Yuan, Z | 1 |
| Barale, JC; Bouillon, A; Chy, S; Eam, R; Kauy, C; Ke, S; Khean, C; Khim, N; Kim, S; Kloeung, N; Kul, C; Leang, R; Mairet-Khedim, M; Ringwald, P; Roesch, C; Srun, S; Witkowski, B | 1 |
| Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M | 1 |
7 review(s) available for piperaquine and artemisinin
| Article | Year |
|---|---|
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Quantification of the antimalarial piperaquine in plasma.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Quinolines; Tandem Mass Spectrometry | 2008 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
Topics: Africa; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines | 2015 |
Prevention and control of malaria in pregnancy - new threats, new opportunities?
Topics: Adult; Animals; Antimalarials; Artemisinins; Culicidae; Drug Combinations; Drug Resistance; Female; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications, Parasitic; Primary Prevention; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
20 trial(s) available for piperaquine and artemisinin
| Article | Year |
|---|---|
[Comparative study of artemisinin suppositories and piperaquine phosphate in the treatment of falciparum malaria].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Child; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Suppositories | 1989 |
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2006 |
Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Prospective Studies; Quinolines; Thailand; Treatment Outcome | 2008 |
Dose ranging studies of new artemisinin-piperaquine fixed combinations compared to standard regimens of artemisisnin combination therapies for acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Prospective Studies; Quinolines; Thailand | 2007 |
A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Integrative Medicine; Malaria, Falciparum; Male; Quinolines; Treatment Outcome; Young Adult | 2009 |
Effect of nutritional status on response to treatment with artemisinin-based combination therapy in young Ugandan children with malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Infant; Malaria; Malnutrition; Parasitemia; Quinolines | 2011 |
The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Topics: Adolescent; Adult; Amodiaquine; Animals; Artemisinins; Blood; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors; Treatment Outcome; Vietnam; Young Adult | 2012 |
Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Population Surveillance; Quinolines; Senegal; Young Adult | 2013 |
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lopinavir; Malaria; Male; Nevirapine; Parasitemia; Quinolines; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Uganda | 2014 |
Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
Topics: Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Treatment Failure | 2014 |
Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment.
Topics: Adolescent; Adult; Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Treatment Failure; Young Adult | 2015 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based combination treatments of uncomplicated falciparum malaria.
Topics: Adolescent; Amodiaquine; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Prognosis; Quinolines; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects.
Topics: Adolescent; Adult; Aged; Aminoquinolines; Antimalarials; Artemisinins; Drug Interactions; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Half-Life; Healthy Volunteers; Humans; Lumefantrine; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Quinolines; Young Adult | 2016 |
Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon.
Topics: Adolescent; Adult; Age Factors; Antimalarials; Artemisinins; Child; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combination; Female; Fosfomycin; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Proof of Concept Study; Quinolines; Treatment Outcome; Young Adult | 2018 |
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
Topics: Adolescent; Adult; Amodiaquine; Anthraquinones; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult | 2020 |
Safety and efficacy of artemisinin-piperaquine for treatment of COVID-19: an open-label, non-randomised and controlled trial.
Topics: Adult; Antiviral Agents; Artemisinins; COVID-19 Drug Treatment; Drug Therapy, Combination; Female; Humans; Long QT Syndrome; Lung Diseases; Male; Middle Aged; Quinolines; RNA, Viral; SARS-CoV-2; Viral Load | 2021 |
Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Cluster Analysis; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Myanmar; Primaquine; Quinolines; Young Adult | 2021 |
Artemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Grande Comore island: an open-label, non-randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines | 2023 |
33 other study(ies) available for piperaquine and artemisinin
| Article | Year |
|---|---|
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |
Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Cambodia; Child; Drug Administration Schedule; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Pilot Projects; Plasmodium falciparum; Population Surveillance; Primaquine; Quinolines; Treatment Outcome | 2010 |
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania | 2013 |
Defining the timing of action of antimalarial drugs against Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors | 2013 |
Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation.
Topics: Alleles; Antigens, Protozoan; Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines; Tetrahydrofolate Dehydrogenase | 2014 |
Auto-induction of phase I and phase II metabolism of artemisinin in healthy Chinese subjects after oral administration of a new artemisinin-piperaquine fixed combination.
Topics: Administration, Oral; Adult; Artemisinins; Asian People; Biotransformation; Chromatography, Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Drug Combinations; Humans; Plasma; Quinolines; Tandem Mass Spectrometry | 2014 |
Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Chromosomes; Drug Resistance, Multiple; Erythrocytes; Humans; INDEL Mutation; Malaria, Falciparum; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinolines; Thailand | 2014 |
Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis.
Topics: Africa; Antimalarials; Artemisinins; Cost-Benefit Analysis; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Models, Theoretical; Quinolines; Seasons | 2014 |
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult | 2015 |
Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene.
Topics: Artemisinins; China; Drug Resistance, Multiple; Genotype; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum; Quinolines | 2015 |
Optimum population-level use of artemisinin combination therapies: a modelling study.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Administration Schedule; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure | 2015 |
Back on TRAC: New trial launched in bid to outpace multidrug-resistant malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinolines | 2016 |
Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asymptomatic Diseases; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Real-Time Polymerase Chain Reaction; Treatment Outcome; Young Adult | 2016 |
How to tackle antimalarial resistance?
Topics: Antimalarials; Artemisinins; Clinical Studies as Topic; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Quinolines | 2017 |
Influence of the
Topics: Alleles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gene Dosage; Genotyping Techniques; Inhibitory Concentration 50; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Thailand | 2017 |
A Variant PfCRT Isoform Can Contribute to
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Gene Editing; Humans; Lethal Dose 50; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins; Quinolines | 2017 |
[Elimination in South-East Asia? The role of antimalarial drugs].
Topics: Antimalarials; Artemether; Artemisinins; Asia, Southeastern; Disease Eradication; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Quinolines | 2016 |
Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia.
Topics: Adult; Antipruritics; Artemisinins; Cambodia; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phylogeny; Plasmodium falciparum; Protozoan Proteins; Quinolines; Treatment Failure | 2017 |
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Drug-resistant malaria advances in Mekong.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Vietnam; World Health Organization | 2017 |
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy.
Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemisinins; Biotransformation; Drug Administration Schedule; Drug Combinations; Half-Life; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Tablets; Young Adult | 2018 |
Large-scale Artemisinin-Piperaquine Mass Drug Administration With or Without Primaquine Dramatically Reduces Malaria in a Highly Endemic Region of Africa.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Comoros; DNA, Protozoan; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria, Falciparum; Male; Mass Drug Administration; Parasitemia; Plasmodium falciparum; Polymorphism, Genetic; Primaquine; Quinolines; Treatment Outcome; Young Adult | 2018 |
Efficacy of artemisinin-based combination therapies and prevalence of molecular markers associated with artemisinin, piperaquine and sulfadoxine-pyrimethamine resistance in Sierra Leone.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Mutation; Quinolines; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Models, Theoretical; Plasmodium falciparum; Quinolines | 2018 |
Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Aspartic Acid Endopeptidases; Child; Chloroquine; Drug Resistance; Folic Acid Antagonists; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Uganda | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Effect of artemisinin-piperaquine treatment on the electrocardiogram of malaria patients.
Topics: Adult; Antimalarials; Artemisinins; Drug Therapy, Combination; Electrocardiography; Female; Humans; Long QT Syndrome; Malaria, Falciparum; Male; Middle Aged; Quinolines; Retrospective Studies | 2019 |
Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers
Topics: Algorithms; Antigens, Protozoan; Antimalarials; Artemisinins; Biomarkers; Clinical Trials as Topic; Gene Expression; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Merozoite Surface Protein 1; Models, Statistical; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Quinolines; Time Factors; Treatment Outcome | 2019 |
Sub-acute toxicological study of artemisinin-piperaquine tablets in rhesus monkeys.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Body Temperature; Dose-Response Relationship, Drug; Drug Combinations; Feeding Behavior; Female; Gastrointestinal Tract; Macaca mulatta; Male; Nervous System; No-Observed-Adverse-Effect Level; Quinolines; Tablets; Toxicity Tests, Subacute; Weight Loss | 2019 |
Healthcare professionals' perspective can guide post-marketing surveillance of artemisinin-based combination therapy in Uganda.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Female; Health Personnel; Humans; Logistic Models; Malaria; Male; Patient Compliance; Plasmodium falciparum; Product Surveillance, Postmarketing; Quinolines; Sesquiterpenes; Surveys and Questionnaires; Tablets; Treatment Failure; Uganda | 2020 |
Metabolism is not a Major Contributor to the Toxicity of Piperaquine, a Long-acting Antimalarial Agent in Artemisinin-based Combination Therapy.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Inactivation, Metabolic; Kidney Diseases; Metabolic Networks and Pathways; Mice; NF-kappa B; Piperazines; Quinolines; Tumor Suppressor Protein p53 | 2021 |
Reproductive and endocrine effects of artemisinin, piperaquine, and artemisinin-piperaquine combination in rats.
Topics: Adrenocorticotropic Hormone; Animals; Antimalarials; Artemisinins; Estradiol; Female; Follicle Stimulating Hormone; Hyperemia; Hyperplasia; Luteinizing Hormone; Piperazines; Prolactin; Prostaglandins; Quinolines; Rats; Rats, Wistar | 2022 |
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Prevalence; Quinolines | 2023 |