piperaquine has been researched along with 1-hydroxymethylmidazolam in 1 studies
| Studies (piperaquine) | Trials (piperaquine) | Recent Studies (post-2010) (piperaquine) | Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) |
|---|---|---|---|---|---|
| 638 | 227 | 497 | 163 | 46 | 49 |
| Protein | Taxonomy | piperaquine (IC50) | 1-hydroxymethylmidazolam (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 10 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashton, M; Aziz, MY; Hoffmann, KJ | 1 |
1 other study(ies) available for piperaquine and 1-hydroxymethylmidazolam
| Article | Year |
|---|---|
Inhibition of CYP3A by Antimalarial Piperaquine and Its Metabolites in Human Liver Microsomes With IVIV Extrapolation.
Topics: Antimalarials; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Microsomes, Liver; Midazolam; Quinolines; Tandem Mass Spectrometry | 2018 |