Page last updated: 2024-08-23

piperacillin and probenecid

piperacillin has been researched along with probenecid in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lee, CT; Lim, KB; Sng, EH; Thirumoorthy, T1
Brasch, H; Iven, H2
Wilkowske, CJ; Wright, AJ1
Kakuo, H; Komuro, M; Maeda, T; Matsushita, H; Shimada, J1

Reviews

1 review(s) available for piperacillin and probenecid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for piperacillin and probenecid

ArticleYear
Inhibition of the renal excretion of tazobactam by piperacillin.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:4

    Topics: Animals; beta-Lactamase Inhibitors; Blood Proteins; Depression, Chemical; Dogs; Humans; Inulin; Kidney; Male; Penicillanic Acid; Piperacillin; Probenecid; Protein Binding; Tazobactam

1994

Other Studies

11 other study(ies) available for piperacillin and probenecid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013
Single dose piperacillin in treating uncomplicated gonococcal urethritis in men.
    Genitourinary medicine, 1987, Volume: 63, Issue:5

    Topics: Drug Administration Schedule; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Piperacillin; Probenecid; Urethritis

1987
The effects of antibiotics and uricosuric drugs on the renal elimination of methotrexate and 7-hydroxymethotrexate in rabbits.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Benzbromarone; Ceftriaxone; Furosemide; Kidney; Metabolic Clearance Rate; Methotrexate; Piperacillin; Probenecid; Rabbits; Sulfamethoxazole; Sulfinpyrazone; Uricosuric Agents

1988
Influence of the antibiotics piperacillin, doxycycline, and tobramycin on the pharmacokinetics of methotrexate in rabbits.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Doxycycline; Drug Interactions; Kinetics; Male; Methotrexate; Piperacillin; Probenecid; Rabbits; Tobramycin

1986
The penicillins.
    Mayo Clinic proceedings, 1983, Volume: 58, Issue:1

    Topics: Amoxicillin; Ampicillin; Bacterial Infections; Carbenicillin; Drug Administration Schedule; Drug Evaluation; Drug Hypersensitivity; Drug Synergism; Humans; Penicillin G; Penicillins; Piperacillin; Probenecid; Ticarcillin

1983