Page last updated: 2024-08-23

piperacillin and clavulanic acid

piperacillin has been researched along with clavulanic acid in 99 studies

Research

Studies (99)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (20.20)	18.7374
1990's	28 (28.28)	18.2507
2000's	32 (32.32)	29.6817
2010's	12 (12.12)	24.3611
2020's	7 (7.07)	2.80

Authors

Authors	Studies
Hall, TW; Ishida, N; Maiti, SN; Micetich, RG; Nakai, A; Ogawa, K; Spevak, P; Tanaka, M; Yamabe, S; Yamazaki, T	1
Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O	1
Aubert, D; Naas, T; Nordmann, P; Ozcan, A	1
Arlet, G; Loli, A; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS	1
Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M	1
Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS	1
Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F	1
Girlich, D; Leclercq, R; Naas, T; Nordmann, P	1
Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J	1
Bonnet, R; Neuwirth, C; Robin, F; Siebor, E	1
Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B	1
Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D	1
Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ	1
Bonnet, R; Caniça, M; Manageiro, V; Mendonça, N	1
Lombardo, F; Obach, RS; Waters, NJ	1
Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR	1
Arakawa, Y; Ishikawa, K; Nagano, N; Nagano, Y; Wachino, J	1
Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J	1
Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX	1
Chanteperdrix, V; Croizé, J; Nordmann, P; Poirel, L; Potron, A	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Ghori, S; Griggs, DJ; Johnson, MM; Mott, A; Peake, L; Piddock, LJ	1
Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D	1
Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX	1
De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A	1
Girlich, D; Nordmann, P; Poirel, L	1
Bethel, CR; Bonomo, RA; Distler, AM; Kasuboski, C; Papp-Wallace, KM; Taracila, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS	1
Bonomo, RA; Distler, AM; Endimiani, A; Hornick, JM; Hujer, AM; Hujer, KM; Papp-Wallace, KM; Taracila, M	1
Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E	1
Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS	1
Bethel, CR; Bonomo, RA; Caselli, E; Drawz, SM; Dwulit-Smith, JR; Papp-Wallace, KM; Prati, F; Rodkey, EA; Romagnoli, C; Smith, KM; Taracila, MA; van den Akker, F; Winkler, ML; Xu, Y	1
Kunii, O; Miyashita, T; Ono, Y	1
Cullmann, W	1
Akova, M; Livermore, DM; Yang, Y	1
Kempers, J; MacLaren, DM	1
Sanders, CC; Sanders, WE; Thomson, KS; Weber, DA	1
Acar, JF; Coutrot, A; Ferré, B; Gutmann, L; Kitzis, MD	1
Jacobus, NV; Kuck, NA; Petersen, PJ; Testa, RT; Weiss, WJ	1
Aronoff, SC; Jacobs, MR; Johenning, S; Yamabe, S	1
Alivisatos, MR; Bollinger, MR; Greenberg, RN	1
Jehl, F; Monteil, H	1
Carlisle, P; D'Olimpio, JT; McKitrick, JC; Miller, M; Sheridan, CA; Wiernik, PH; Wollner, DI	1
Henry, D; Ngui-Yen, J; Skidmore, AG; Smith, A; Smith, JA	1
Donowitz, GR; Harman, C; Hess, CE; Scheld, M; Williams, ME	1
Cobbs, CG; Pierce, MA; Wofford, JD	1
Aldridge, KE; Derks, FW; Marier, RL; Martin, DH; Sanders, CV	1
Holloway, WJ	1
Link, AS	1
Cox, CE	1
Fu, KP; Neu, HC	1
Ullmann, U	1
Clarke, AM; Zemcov, SJ	1
Maskell, JP; Simpson, CN; Williams, JD	1
Bidwell, JL; Bywater, MJ; Holt, HA; Reeves, DS	1
File, TM; Tan, JS	1
Duval, J; Leclercq, R	1
Jones, R; Satishchandran, V; Shapiro, T; Suh, B; Truant, AL	1
Amyes, SG; London, N; Stobberingh, E; Thomson, CJ	1
Chanal, C; Cluzel, R; Henquell, C; Labia, R; Sirot, D; Sirot, J	1
Chandy, M; Ebenezer, S; Jesudason, MV; Lalitha, MK	1
Baquero, F; Reig, M	1
Edelstein, MA; Edelstein, PH	1
Duchateau, V; Husson, M; Kinzig, M; Lambert, C; Sörgel, F; Van der Auwera, P	1
Alonso, JM; Fournier, JL; Jacolot, AC; Petitjean, OJ; Ramisse, F; Scavizzi, MR; Szatanik, M	1
Livermore, DM; Yuan, M	1
Miller, LA; Poupard, JA; Rittenhouse, SF; Utrup, LJ	1
Knapp, CC; Ludwig, MD; Pohlman, JK; Washington, JA	1
Klepser, ME; Marangos, MN; Nicolau, DP; Nightingale, CH; Quintiliani, R; Zhu, Z	1
Blumer, JL; Bonafede, ME	1
Bonomo, RA; Rudin, SA; Shlaes, DM	1
Hanaki, H; Nagayama, A; Nomura, S	1
Gagliardi, NC; Nix, DE; Schentag, JJ; Spivey, JM; Symonds, WT; Thomas, JK; Wilton, JH	1
Constantoulaki, S; Paniara, O; Platsouka, E; Zissis, NP	1
Martínek, J; Melenovsky, V; Morávek, J; Spicák, J; Závada, F	1
Gardner, VM; Lister, PD; Sanders, CC	1
Betriu, C; Gómez, M; Palau, ML; Picazo, JJ; Sánchez, A	1
Miranda, E; Sader, HS; Sejas, L; Tosin, I	1
Bauer, C; Horsmans, Y; Schoonbroodt, D; Wagner, C	1
Lister, PD	1
Chen, Y; Gao, L; Hou, F; Li, J	1
Niki, Y	1
Bonnefoy, A; Delachaume, C; Dupuis-Hamelin, C; Fairley, M; Guitton, M; Lampilas, M; Seys, C; Stachyra, T; Steier, V	1
Ashkenazi, S; Bishara, J; Lev, B; Levy, I; Livne, G; Ofir, O; Pitlik, S; Samra, Z	1
Nord, CE	1
Broide, E; Raveh, D; Rudensky, B; Yinnon, AM	1
Anuradha, K; Lakshmi, V; Sailaja, VV; Satheesh, T; Umabala, P	1
Bleeker-Rovers, CP; Koopman, M; Mannaerts, L; Punt, CJ; van Herpen, CM	1
Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L	1
Baquero, F; Cantón, R; Galán, JC; Novais, A; Ripoll, A; Rodríguez-Domínguez, MJ; Turrientes, MC	1
Ledger, TS	1
Neugebauer, D; Niesyto, K	1
Allegaert, K; Cristea, S; De Cock, P; de Jaeger, A; De Paepe, P; Knibbe, CAJ; Krekels, EHJ	1
Deligios, M; Fiamma, M; Paglietti, B; Rubino, S; Sacarlal, J; Santona, A; Simbine, SE; Sumbana, JJ; Taviani, E; Zimba, T	1
Dong, L; Feng, Y; Lin, Q; Lin, T	1
Arenere-Mendoza, M; Fernández-de-Gamarra-Martínez, E; Fernández-Polo, A; González-Suárez, S; Gutiérrez-Urbón, JM; Nicolás-Picó, J; Rodríguez-Mateos, ME; Sánchez-Yáñez, E	1
Caljon, B; Crombé, F; De Geyter, D; Demuyser, T; Janssen, T; Muyldermans, A; Piérard, D; Seyler, L; Vanstokstraeten, R; Wybo, I	1
Dalğıç, D; Kandemir, T; Nağıyev, T; Üçkayabaşı, A	1

Reviews

4 review(s) available for piperacillin and clavulanic acid

Article	Year
Efficacy and safety of piperacillin/tazobactam in skin and soft tissue infections. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1994, Issue:573 Topics: Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Necrosis; Penicillanic Acid; Piperacillin; Skin Diseases, Bacterial; Soft Tissue Infections; Tazobactam; Ticarcillin	1994
Role of newer broad-spectrum beta-lactam and fluoroquinolone antibiotics in children. Advances in pediatric infectious diseases, 1996, Volume: 12 Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbapenems; Cephalosporins; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Fluoroquinolones; Humans; Molecular Structure; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam; Ticarcillin	1996
Beta-lactamase inhibitor combinations with extended-spectrum penicillins: factors influencing antibacterial activity against enterobacteriaceae and Pseudomonas aeruginosa. Pharmacotherapy, 2000, Volume: 20, Issue:9 Pt 2 Topics: beta-Lactamases; Clavulanic Acid; Drug Therapy, Combination; Enterobacteriaceae; Enzyme Inhibitors; Penicillanic Acid; Penicillin Resistance; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin	2000
[Fundamental and clinical studies on beta-lactamase inhibitors]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:4 Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam	2001

Trials

8 trial(s) available for piperacillin and clavulanic acid

Article	Year
A comparative trial of moxalactam plus ticarcillin and clavulanic acid or piperacillin as empiric antibiotic therapy for febrile cancer patients. Journal of clinical pharmacology, 1987, Volume: 27, Issue:9 Topics: Bacterial Infections; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fever; Humans; Male; Middle Aged; Moxalactam; Neoplasms; Penicillins; Piperacillin; Ticarcillin	1987
A controlled study of ticarcillin plus clavulanic acid versus piperacillin as empiric therapy for fever in the immunocompromised host. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Bacterial Infections; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Fever; Humans; Immune Tolerance; Leukocyte Count; Neutrophils; Penicillins; Piperacillin; Ticarcillin	1985
Comparative trial of ticarcillin plus clavulanic acid and piperacillin in the treatment of acute bacterial infection. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Acute Disease; Adult; Aged; Bacterial Infections; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Middle Aged; Penicillins; Piperacillin; Sepsis; Ticarcillin	1985
Treatment of infections in hospitalized patients with ticarcillin plus clavulanic acid. A comparative study. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefoxitin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Gram-Negative Bacteria; Hospitalization; Humans; Male; Penicillins; Piperacillin; Respiratory Tract Infections; Sepsis; Ticarcillin; Tobramycin	1985
Comparative study of ticarcillin plus clavulanate potassium versus piperacillin in the treatment of hospitalized patients with urinary tract infections. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Adult; Aged; Bacterial Infections; Child; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Hospitalization; Humans; Middle Aged; Penicillins; Piperacillin; Ticarcillin; Urinary Tract Infections	1985
Comparison of the bactericidal activities of piperacillin-tazobactam, ticarcillin-clavulanate, and ampicillin-sulbactam against clinical isolates of Bacteroides fragilis, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2 Topics: Adult; Ampicillin; Bacteroides fragilis; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Cross-Over Studies; Drug Therapy, Combination; Enterococcus faecalis; Escherichia coli; Female; Humans; Male; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Serum Bactericidal Test; Sulbactam; Tazobactam; Ticarcillin	1997
Assessment of the enzymuria resulting from gentamicin alone and combinations of gentamicin with various beta-lactam antibiotics. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:6 Topics: Acetylglucosaminidase; Adolescent; Adult; Anti-Bacterial Agents; CD13 Antigens; Ceftazidime; Clavulanic Acid; Clavulanic Acids; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Kidney Tubules; Male; Middle Aged; Piperacillin; Ticarcillin	1997
A randomized controlled clinical trial on piperacillin/tazobactam versus ticarcillin/clavulanic acid for the treatment of bacterial infections. Chinese medical journal, 1998, Volume: 111, Issue:11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli Infections; Female; Humans; Male; Penicillanic Acid; Penicillins; Piperacillin; Pneumonia; Respiratory Tract Infections; Tazobactam; Ticarcillin; Urinary Tract Infections	1998

Other Studies

87 other study(ies) available for piperacillin and clavulanic acid

Article	Year
Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Escherichia coli; Penicillanic Acid; Sulbactam; Tazobactam; Triazoles	1987
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation	2007
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data	2007
SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillinase; Plasmids; Sequence Analysis, DNA	2007
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA	2007
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet	2007
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA	2007
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity	2007
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam	2007
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity	2007
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity	2008
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA	2008
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary	2008
Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactamases; Kinetics; Klebsiella pneumoniae	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity	2008
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Amino Acid Sequence; beta-Lactamases; Blotting, Southern; Ceftazidime; Cephalosporins; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shigella sonnei	2009
Genetic variability among ampC genes from acinetobacter genomic species 3. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain	2009
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping	2009
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Amino Acid Sequence; Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Campylobacter jejuni; Carbenicillin; Cephalosporins; Chickens; Cloxacillin; Isoelectric Focusing; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Piperacillin; Polymerase Chain Reaction; Sequence Alignment; Ticarcillin	2009
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid	2009
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity	2010
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2010
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology	2010
Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Sulbactam; Tazobactam	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA	2010
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporinase; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulbactam; Tazobactam	2010
Extended-spectrum cephalosporinase in Acinetobacter baumannii. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8 Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed	2010
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin	2010
Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Circular Dichroism; Clavulanic Acid; Crystallography, X-Ray; Drug Design; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds	2013
[Chemical structure, anti-bacterial activity and pharmacokinetics of penicillins]. Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:10 Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Humans; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin	1991
Beta-lactamase inhibitors: relation between kinetic data and in-vitro synergism studies. Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1991, Volume: 275, Issue:4 Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Synergism; Enterobacter cloacae; Escherichia coli; Klebsiella; Penicillanic Acid; Piperacillin; Proteus vulgaris; Pseudomonas aeruginosa; Staphylococcus aureus; Sulbactam; Tazobactam	1991
Interactions of tazobactam and clavulanate with inducibly- and constitutively-expressed Class I beta-lactamases. The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:2 Topics: Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enzyme Induction; Half-Life; Kinetics; Penicillanic Acid; Piperacillin; Tazobactam; Ticarcillin	1990
Piperacillin/tazobactam and ticarcillin/clavulanic acid against resistant Enterobacteriaceae. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:4 Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Hydrogen-Ion Concentration; Penicillanic Acid; Piperacillin; Tazobactam; Ticarcillin	1990
Beta-lactamase production in members of the family Enterobacteriaceae and resistance to beta-lactam-enzyme inhibitor combinations. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillins; Piperacillin; Sulbactam; Ticarcillin	1990
In vitro activity of combinations of beta-lactam antibiotics with beta-lactamase inhibitors against cephalosporinase-producing bacteria. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefotaxime; Cephalosporinase; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Resistance, Microbial; Enterobacteriaceae; Enzyme Induction; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sulbactam; Tazobactam; Ticarcillin	1989
Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:11 Topics: Animals; Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam	1989
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonads. The Journal of antimicrobial chemotherapy, 1986, Volume: 18, Issue:2 Topics: Ampicillin; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Enterobacteriaceae; Mezlocillin; Naphthyridines; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas; Sulbactam; Ticarcillin	1986
In vitro activity of piperacillin, ticarcillin, mezlocillin, ticarcillin-clavulanic acid, aztreonam, ceftazidime, azlocillin, cefoperazone, and thienamycin against Pseudomonas aeruginosa. Clinical therapeutics, 1986, Volume: 8, Issue:6 Topics: Anti-Bacterial Agents; Azlocillin; Aztreonam; Cefoperazone; Ceftazidime; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Mezlocillin; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Thienamycins; Ticarcillin	1986
[Comparative activity of ticarcillin-clavulanic acid and various beta-lactams against Pseudomonas maltophilia]. Pathologie-biologie, 1987, Volume: 35, Issue:5 Pt 2 Topics: Anti-Bacterial Agents; Azlocillin; Cefoperazone; Ceftazidime; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Microbial Sensitivity Tests; Moxalactam; Penicillins; Piperacillin; Pseudomonas; Ticarcillin	1987
In vitro activities of enoxacin, ticarcillin plus clavulanic acid, aztreonam, piperacillin, and imipenem and comparison with commonly used antimicrobial agents. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2 Topics: Anti-Bacterial Agents; Aztreonam; Clavulanic Acid; Clavulanic Acids; Enoxacin; Imipenem; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Piperacillin; Species Specificity; Thienamycins; Ticarcillin	1985
Safety and effectiveness of ticarcillin plus clavulanic acid in the treatment of community-acquired acute pyelonephritis in adult women. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Acute Disease; Adolescent; Adult; Aged; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Evaluation; Escherichia coli Infections; Female; Humans; Middle Aged; Penicillins; Piperacillin; Pyelonephritis; Ticarcillin	1985
Efficacy and safety of ticarcillin plus clavulanic acid and piperacillin in patients with lower respiratory tract infections. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Adult; Aged; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillins; Piperacillin; Respiratory Tract Infections; Ticarcillin	1985
Synergistic activity of piperacillin in combination with beta-lactamase inhibitors. Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Drug Synergism; Penicillanic Acid; Penicillins; Piperacillin; Sulbactam	1980
Bacteriological investigations with beta-lactamase inhibitors. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious..., 1982, Volume: 252, Issue:2 Topics: Amoxicillin; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Enterobacteriaceae; Penicillanic Acid; Penicillin G; Penicillins; Piperacillin; Pseudomonas aeruginosa	1982
Clavulanic acid in combination with ticarcillin: an in-vitro comparison with other beta-lactams. The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:2 Topics: Anti-Bacterial Agents; Bacteroides fragilis; Cefotaxime; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Enterobacteriaceae; Haemophilus influenzae; Microbial Sensitivity Tests; Penicillins; Piperacillin; Pseudomonas aeruginosa; Staphylococcus aureus; Ticarcillin	1984
The effect of clavulanic acid on the susceptibility of Bacteroides fragilis to three acyl-ureidopenicillins, ampicillin and carbenicillin. The Journal of antimicrobial chemotherapy, 1984, Volume: 14, Issue:2 Topics: Ampicillin; Azlocillin; Bacteroides fragilis; beta-Lactamases; Carbenicillin; Clavulanic Acid; Clavulanic Acids; Isoelectric Focusing; Mezlocillin; Microbial Sensitivity Tests; Piperacillin	1984
Comparative activity in vitro of piperacillin. The Journal of antimicrobial chemotherapy, 1982, Volume: 9 Suppl B Topics: Bacteria; Bacterial Infections; beta-Lactamases; beta-Lactams; Clavulanic Acid; Drug Stability; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; R Factors	1982
[Bactericidal activity of combinations of ticarcillin-clavulanic acid or other beta-lactams (amoxicillin, piperacillin-tazobactam, ticarcillin) with gentamicin against Enterococcus faecalis and E. faecium]. Pathologie-biologie, 1995, Volume: 43, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; Enzyme Inhibitors; Gentamicins; Humans; In Vitro Techniques; Penicillanic Acid; Penicillin Resistance; Piperacillin; Tazobactam; Ticarcillin	1995
In vitro activity of beta-lactamase inhibitors against clinical isolates of Acinetobacter species. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:2 Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Cefotaxime; Ceftazidime; Ceftriaxone; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Sulbactam; Tazobactam	1995
A piperacillin-tazobactam resistant Escherichia coli strain isolated from a faecal sample of a healthy volunteer. FEMS immunology and medical microbiology, 1995, Volume: 11, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Escherichia coli; Feces; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Plasmids; Population Surveillance; Tazobactam	1995
Clinical isolates of Escherichia coli producing multiple TEM mutants resistant to beta-lactamase inhibitors. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:6 Topics: Amoxicillin; Base Sequence; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Escherichia coli; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Piperacillin; Ticarcillin	1994
In vitro evaluation of newer beta-lactam antibiotics against gram negative bacilli isolated from neutropenic patients. Indian journal of cancer, 1994, Volume: 31, Issue:1 Topics: Anti-Bacterial Agents; Azlocillin; Clavulanic Acid; Clavulanic Acids; Drug Evaluation; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Neutropenia; Piperacillin; Pseudomonas aeruginosa; Sepsis; Ticarcillin	1994
Antibacterial activity of clavulanate and tazobactam on Peptostreptococcus spp. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:2 Topics: Amoxicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Peptostreptococcus; Piperacillin; Tazobactam	1994
In vitro extracellular and intracellular activities of clavulanic acid and those of piperacillin and ceftriaxone alone and in combination with tazobactam against clinical isolates of Legionella species. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2 Topics: Animals; Ceftriaxone; Cells, Cultured; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Therapy, Combination; Extracellular Space; Guinea Pigs; Intracellular Fluid; Legionella; Legionella pneumophila; Legionnaires' Disease; Macrophages, Alveolar; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Tazobactam	1994
Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9 Topics: Adult; beta-Lactamase Inhibitors; Biological Assay; Chromatography, High Pressure Liquid; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Serum Bactericidal Test; Tazobactam; Ticarcillin	1993
Assessment of two penicillins plus beta-lactamase inhibitors versus cefotaxime in treatment of murine Klebsiella pneumoniae infections. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:2 Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefotaxime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Drug Combinations; Drug Therapy, Combination; Female; Klebsiella Infections; Klebsiella pneumoniae; Lung; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Pneumonia, Bacterial; Tazobactam; Ticarcillin	1996
Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe. The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Enzyme Inhibitors; Europe; Humans; Intensive Care Units; Klebsiella; Klebsiella Infections; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Piperacillin; Tazobactam	1996
Evaluation of 500 gram negative isolates to determine the number of major susceptibility interpretation discrepancies between the Vitek and MicroScan Walkaway for 9 antimicrobial agents. Diagnostic microbiology and infectious disease, 1996, Volume: 26, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Enterobacter; Escherichia coli; Imipenem; Klebsiella pneumoniae; Mezlocillin; Microbial Sensitivity Tests; Norfloxacin; Penicillins; Piperacillin; Proteus mirabilis; Pseudomonas aeruginosa; Quality Control; Reproducibility of Results; Sulbactam; Thienamycins; Ticarcillin	1996
Timed killing kinetic studies of the interaction between ciprofloxacin and beta-lactams against gram-negative bacilli. Diagnostic microbiology and infectious disease, 1996, Volume: 26, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Therapy, Combination; Enterobacter cloacae; Enzyme Inhibitors; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens; Tazobactam; Ticarcillin; Time Factors	1996
Tazobactam is a potent inactivator of selected inhibitor-resistant class A beta-lactamases. FEMS microbiology letters, 1997, Mar-01, Volume: 148, Issue:1 Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Kinetics; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam	1997
Tazobactam-piperacillin compared with sulbactam-ampicillin, clavulanic acid-ticarcillin, sulbactam-cefoperazone, and piperacillin for activity against beta-lactamase-producing bacteria isolated from patients with complicated urinary tract infections. Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:2 Topics: Ampicillin; beta-Lactamase Inhibitors; Cefoperazone; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Retrospective Studies; Sulbactam; Tazobactam; Ticarcillin; Urinary Tract; Urinary Tract Infections	1997
Comparative in vitro evaluation of piperacillin/tazobactam in a tertiary care hospital. Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:5 Topics: Amoxicillin; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Intensive Care Units; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Tazobactam	1997
Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis. Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:1 Topics: Amikacin; Amoxicillin; Animals; Anti-Bacterial Agents; Cefoperazone; Clavulanic Acid; Female; Ofloxacin; Pancreas; Pancreatic Juice; Pancreatitis, Acute Necrotizing; Piperacillin; Rats; Rats, Wistar; Taurocholic Acid; Tissue Distribution	1999
Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:4 Topics: Anti-Bacterial Agents; Cephalosporinase; Clavulanic Acid; Enzyme Induction; Enzyme Inhibitors; Genes, Bacterial; Humans; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin	1999
In-vitro susceptibilities of species of the Bacteroides fragilis group to newer beta-lactam agents. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:1 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Cefoxitin; Ceftizoxime; Chloramphenicol; Clavulanic Acid; Clindamycin; Drug Therapy, Combination; Enzyme Inhibitors; Imipenem; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Species Specificity; Sulbactam; Tazobactam; Thienamycins; Ticarcillin	1999
Comparative evaluation of the in vitro activity of three combinations of beta-lactams with beta-lactamase inhibitors: piperacillin/tazobactam, ticarcillin/clavulanic acid and ampicillin/sulbactam. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2000, Volume: 4, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Clavulanic Acid; Cross Infection; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam; Ticarcillin	2000
Liver abscesses due to Fusobacterium species. Liver, 2000, Volume: 20, Issue:3 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Fusobacterium; Fusobacterium Infections; Humans; Liver Abscess; Male; Metronidazole; Piperacillin; Tomography, X-Ray Computed	2000
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:2 Topics: Azepines; Bacteria; beta-Lactamases; Ceftazidime; Cephalosporins; Clavulanic Acid; Dealkylation; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Staphylococcus aureus; Sulfuric Acid Esters; Tazobactam	2004
Antibacterial susceptibility of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli. The Israel Medical Association journal : IMAJ, 2005, Volume: 7, Issue:5 Topics: Adult; Amikacin; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Child; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Humans; In Vitro Techniques; Israel; Klebsiella pneumoniae; Microbial Sensitivity Tests; Odds Ratio; Penicillanic Acid; Piperacillin; Prevalence; Tazobactam	2005
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanic acid and sulbactam combined with ampicillin and piperacillin against beta-lactamase producing anaerobic bacteria. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Clavulanic Acid; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam	1989
Susceptibilities of ESBL-producing Enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid. Chemotherapy, 2007, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Drug Interactions; Ertapenem; Escherichia coli; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins	2007
Sensitivity pattern of gram negative bacilli to three beta-lactam/beta-lactamase inhibitor combinations using the automated API system. Indian journal of medical microbiology, 2007, Volume: 25, Issue:3 Topics: Acinetobacter; Amoxicillin; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Enterobacteriaceae; Enzyme Inhibitors; Gram-Negative Bacteria; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas; Stenotrophomonas; Tazobactam; Ticarcillin	2007
Pylephlebitis after a duodenal ulcer in a patient with metastasised colon carcinoma treated with chemotherapy and bevacizumab: a case report. The Netherlands journal of medicine, 2009, Volume: 67, Issue:2 Topics: Aged; Amoxicillin; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bacterial Infections; Bevacizumab; Clavulanic Acid; Colorectal Neoplasms; Duodenal Ulcer; Humans; Male; Penicillanic Acid; Piperacillin; Portal Vein; Tazobactam; Thrombophlebitis	2009
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins	2009
In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario? Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Clavulanic Acid; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Plasmids; Selection, Genetic; Tazobactam	2011
BMJ case reports, 2018, Mar-27, Volume: 2018 Topics: Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clindamycin; Diagnosis, Differential; Female; Humans; Middle Aged; Penicillanic Acid; Penicillin G; Peritonitis; Piperacillin; Streptococcal Infections; Streptococcus pyogenes; Tazobactam; Treatment Outcome	2018
Linear Copolymers Based on Choline Ionic Liquid Carrying Anti-Tuberculosis Drugs: Influence of Anion Type on Physicochemical Properties and Drug Release. International journal of molecular sciences, 2020, Dec-30, Volume: 22, Issue:1 Topics: Aminosalicylic Acid; Anions; Antitubercular Agents; Choline; Clavulanic Acid; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fusidic Acid; Hydrophobic and Hydrophilic Interactions; Ionic Liquids; Micelles; Piperacillin; Polymers; Proton Magnetic Resonance Spectroscopy; Spectrophotometry	2020
Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3. The AAPS journal, 2021, 05-04, Volume: 23, Issue:3 Topics: Adolescent; Amoxicillin; Biological Variation, Population; Cefazolin; Child; Child, Preschool; Clavulanic Acid; Drug Interactions; Glomerular Filtration Rate; Humans; Infant; Infant, Newborn; Kidney; Male; Models, Biological; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Piperacillin; Renal Elimination	2021
High-risk lineages among extended-spectrum β-lactamase-producing Escherichia coli from extraintestinal infections in Maputo Central Hospital, Mozambique. International journal of antimicrobial agents, 2022, Volume: 60, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefotaxime; Ceftazidime; Ciprofloxacin; Clavulanic Acid; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Extraintestinal Pathogenic Escherichia coli; Gentamicins; Hospitals; Humans; Iron; Mozambique; Piperacillin; Tazobactam; Trimethoprim, Sulfamethoxazole Drug Combination	2022
Respiratory Care of Big Data Communication to Prevent Respiratory Tract Infection Nursing Analysis of Patients with Heart Failure. BioMed research international, 2022, Volume: 2022 Topics: Anti-Bacterial Agents; Big Data; Ceftazidime; Clavulanic Acid; Communication; Heart Failure; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Respiratory Tract Infections	2022
PAUSATE Study: Prevalence and appropriateness of the use of antimicrobials in Spanish hospitals. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 08-02, Volume: 46, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Clavulanic Acid; Cross-Sectional Studies; Hospitals; Humans; Meropenem; Piperacillin; Prevalence; Tazobactam	2022
Genotypic resistance determined by whole genome sequencing versus phenotypic resistance in 234 Escherichia coli isolates. Scientific reports, 2023, 01-09, Volume: 13, Issue:1 Topics: Amikacin; Amoxicillin; Anti-Bacterial Agents; Cefepime; Cefotaxime; Ceftazidime; Ciprofloxacin; Clavulanic Acid; Escherichia coli; Escherichia coli Infections; Genotype; Gentamicins; Humans; Meropenem; Microbial Sensitivity Tests; Phenotype; Piperacillin; Retrospective Studies; Tazobactam; Tobramycin; Whole Genome Sequencing	2023
[Relationship of Hypervirulent Capsular Genotypes of Klebsiella pneumoniae with Antibiotic Susceptibility and Beta-Lactamase Genes]. Mikrobiyoloji bulteni, 2023, Volume: 57, Issue:1 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Clavulanic Acid; Colistin; Drug Resistance, Bacterial; Genotype; Klebsiella pneumoniae; Microbial Sensitivity Tests; Piperacillin; Tazobactam	2023