Page last updated: 2024-08-23

piperacillin and ceftazidime

piperacillin has been researched along with ceftazidime in 167 studies

Research

Studies (167)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (1.20)18.2507
2000's114 (68.26)29.6817
2010's50 (29.94)24.3611
2020's1 (0.60)2.80

Authors

AuthorsStudies
Apiwattanakul, N; Endou, H; Jariyawat, S; Kanai, Y; Sekine, T; Sophasan, S; Takeda, M1
Adam, G; Buynak, JD; Doppalapudi, VR; Nidamarthy, SD; Petersen, PJ; Rao, AS1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cattoir, V; Nordmann, P; Poirel, L; Soares, A; Soussy, CJ1
Alba, L; Chen, Y; Garber, E; Saiman, L; Tabibi, S; Zhou, J1
Cornaglia, G; Koncan, R; Mazzariol, A; Roelofsen, E; Voss, A1
Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O1
Aubert, D; Naas, T; Nordmann, P; Ozcan, A1
Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P1
Correa, A; Kattan, JN; Lolans, K; Lopez, JA; Quinn, JP; Villegas, MV1
Arlet, G; Loli, A; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS1
Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N1
Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A1
Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F1
Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M1
Adams, J; Paterson, DL; Peleg, AY1
Ayala, JA; Casellas, JM; Di Conza, J; Ghiglione, B; Gutkind, G; Power, P; Radice, M; Rodríguez, MM1
Kamat, V; Sekar, U; Toleman, MA; Vinodh, H; Walsh, TR1
Kwon, DH; Lu, CD1
Avlami, A; Daikos, GL; Katsilambros, N; Kosmidis, C; Petrikkos, G; Psychogiou, M; Stefanou, I; Tassios, PT; Vasilakopoulou, A1
Bille, J; Lartigue, MF; Nordmann, P; Poirel, L; Wenger, A; Zinsius, C1
Amicosante, G; Caporale, B; Celenza, G; Docquier, JD; Mezzatesta, M; Pellegrini, C; Perilli, M; Rossolini, GM; Stefani, S1
Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR1
Carmeli, Y; Chmelnitsky, I; Leavitt, A; Navon-Venezia, S; Schwaber, MJ1
Grosso, F; Peixe, L; Quinteira, S; Ramos, H1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R1
Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS1
Henrichfreise, B; Luhmer-Becker, I; Wiedemann, B; Wiegand, I1
Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F1
Fung, CP; Hsieh, YP; Hu, WS; Lin, JF; Liu, CP; Yao, SM1
Girlich, D; Leclercq, R; Naas, T; Nordmann, P1
Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J1
Bonnet, R; Neuwirth, C; Robin, F; Siebor, E1
Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL1
Cuzon, G; Demachy, MC; Naas, T; Nordmann, P1
Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B1
Amicosante, G; Celenza, G; De Santis, F; Forcella, C; Pellegrini, C; Perilli, M; Rossolini, GM; Stefani, S1
Avison, MB; Okazaki, A1
Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D1
Cuzon, G; Lartigue, MF; Naas, T; Nordmann, P; Quinn, JP; Villegas, MV1
Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z1
Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ1
Bonnet, R; Caniça, M; Manageiro, V; Mendonça, N1
Cai, JC; Chen, GX; Zhang, R; Zhou, HW1
Doi, Y; Nordmann, P; Paterson, DL; Poirel, L1
Castanheira, M; Deshpande, LM; Martin, CA; Morita, K; Ribes, JA; Sader, HS1
Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC1
Lombardo, F; Obach, RS; Waters, NJ1
Bertolini, T; Chow, C; Froelich, JM; Hermann, T; Murphy, DE; Sun, Z; Wall, D; Webber, SE; Zhou, Y1
Docquier, JD; Frère, JM; Rossolini, GM; Stoczko, M1
Carrillo, B; Esparza-Ahumada, S; Garza-Ramos, U; Hernández, E; Jones, RN; Morfin-Otero, R; Rodriguez-Noriega, E; Sader, HS; Sanchez, A; Silva-Sanchez, J1
Alba, V; Blasco, MD; Espinal, P; Fernández-Cuenca, F; Marti, S; Pascual, A; Ruiz, M; Sánchez-Céspedes, J; Vila, J1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L1
Carmeli, Y; Chmelnitsky, I; Navon-Venezia, S; Strahilevitz, J1
Bauernfeind, A; Keuleyan, E; Markovska, R; Queenan, AM; Rasshofer, R; Schneider, I1
Craft, DW; Hachmeister, L; Hong, SG; Kim, SY; Moland, ES; Sayed, SD; Thomson, KS1
Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR1
Biek, D; Ge, Y; Sahm, DF; Talbot, GH1
Jarlier, V; Mayer, C; Petrella, S; Renard, M; Sougakoff, W; Ziental-Gelus, N1
Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL1
Cattoir, V; Nordmann, P; Poirel, L1
Bogaerts, P; Cuzon, G; Glupczynski, Y; Huang, TD; Naas, T; Nordmann, P1
Arpin, C; Bezian, MC; Coulange, L; Demarthe, F; Dubois, V; Minarini, LA; Nordmann, P; Poirel, L; Quentin, C1
Fujimoto, S; Ike, Y; Okuzumi, K; Tanimoto, K; Tomita, H1
Afif, C; Bagattini, M; Daoud, Z; Di Popolo, A; Khan, AU; Triassi, M; Vitale, D; Zarrilli, R1
Kanamori, M; Kirikae, T; Kitao, T; Miyoshi-Akiyama, T; Morita, K; Okazaki, M; Sekiguchi, J; Watanabe, N1
Hanson, ND; Schmidtke, AJ1
Brown, NP; Pillar, CM; Sahm, DF; Shah, D; Torres, MK1
Chen, H; Chen, M; Wang, H; Yang, H; Yang, Q1
Amicosante, G; De Luca, F; Luzzaro, F; Migliavacca, R; Mugnaioli, C; Pagani, L; Perilli, M; Pini, B; Pollini, S; Rossolini, GM; Spalla, M; Toniolo, A1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Bennett, JW; Herrera, ML; Jorgensen, JH; Lewis, JS; Wickes, BW1
Arakawa, Y; Ishikawa, K; Nagano, N; Nagano, Y; Wachino, J1
Bonnet, R; Delmas, J; Pradel, N; Santini, CL; Wu, LF1
Miriagou, V; Papagiannitsis, CC; Tzouvelekis, LS1
Andlovic, A; Jeverica, S; Karisik, E; Koren, S; Krizan-Hergouth, V; Livermore, DM; Mesko Meglic, K; Müller-Premru, M; Palepou, MF; Pike, R; Seme, K; Woodford, N1
Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C1
Galleni, M; Mammeri, H; Nordmann, P1
Bell, JM; Castanheira, M; Deshpande, LM; Jones, RN; Mendes, RE; Turnidge, JD1
Asensi, MD; Gales, AC; Monteiro, J; Peirano, G; Santos, AF1
Goering, RV; Hanson, ND; Kurpiel, PM; Palepou, MF; Wolter, DJ; Woodford, N1
Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J1
Bradford, PA; Jones, CH; Petersen, PJ; Ruzin, A; Tuckman, M; Visalli, MA1
Nordmann, P; Plésiat, P; Poirel, L; Rodriguez-Martinez, JM1
Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS; Whichard, JM; Zioga, A1
Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD1
Baraniak, A; Bedenic, B; Fiett, J; Gniadkowski, M; Jajic-Bencic, I; Literacka, E; Tonkic, M1
Aquino, EE; Goering, RV; Hanson, ND; Khalaf, N; Robledo, IE; Santé, MI; Vázquez, GJ; Wolter, DJ1
Duljasz, W; Gniadkowski, M; Jebelean, C; Sitter, S; Wojna, A1
Nordmann, P; Poirel, L; Rodríguez-Martínez, JM1
Asgarali, A; Mark, BL; Oliver, A; Stubbs, KA; Vocadlo, DJ1
Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX1
Christiansen, LE; Ciofu, O; Høiby, N; Kirkby, N; Mandsberg, LF; Poulsen, HE1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T1
Chanteperdrix, V; Croizé, J; Nordmann, P; Poirel, L; Potron, A1
Adams-Haduch, JM; Bonomo, RA; Doi, Y; Endimiani, A; O'Keefe, A; Paterson, DL; Sidjabat, HE1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Kotsakis, SD; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS1
Badal, RE; Bouchillon, SK; Hawser, SP; Hoban, DJ; Hsueh, PR; Paterson, DL1
Arlet, G; Bakour, R; Dallenne, C; Geneste, D; Iabadene, H; Messai, Y1
Giakkoupi, P; Miriagou, V; Papagiannitsis, CC; Pappa, O; Polemis, M; Tzouvelekis, LS; Vatopoulos, AC; Zioga, A1
Gales, AC; Nordmann, P; Picão, RC; Poirel, L1
Baraniak, A; Fiett, J; Filczak, K; Gniadkowski, M; Herda, M; Hryniewicz, W; Izdebski, R; Kern-Zdanowicz, I; Łopaciuk, U1
Bauernfeind, A; Keuleyan, E; Markova, B; Markovska, R; Queenan, AM; Schneider, I1
Du, X; Ji, S; Jiang, Y; Li, L; Shen, P; Wei, Z; Yu, Y1
Hancock, RE; Kiffer, CR; Mendes, CM; Sampaio, JL; Schurek, KN; Sinto, S1
De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B1
Boyd, DA; Mulvey, MR1
Carattoli, A; Ellington, MJ; Karisik, E; Livermore, DM; Underwood, A; Woodford, N1
Acosta, J; Chaves, F; Juan, C; Oliver, A; Otero, JR; Sanz, F; Viedma, E; Zamorano, L1
Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D1
Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L1
Higgins, PG; Lehmann, M; Nordmann, P; Poirel, L; Seifert, H1
Bulik, CC; Crandon, JL; Nicolau, DP1
Aggen, JB; Armstrong, ES; Bonomo, RA; Choudhary, Y; Endimiani, A; Hujer, AM; Hujer, KM1
Ichiishi, S; Mikamo, H; Nakao, K; Shibata, T; Tanaka, K; Watanabe, K1
Girlich, D; Nordmann, P; Poirel, L3
Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX1
De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A1
Aggoune-Khinache, N; Bonnet, R; Delmas, J; Naim, M; Robin, F1
Fortineau, N; Nordmann, P; Poirel, L; Rodriguez-Martinez, JM1
Ge, Y; Juan, C; Oliver, A; Pérez, JL; Zamorano, L1
Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS1
Chen, HC; King, CH; Lai, JF; Lauderdale, TL; Shiau, YR1
Akan, OA; Carrër, A; Cuzon, G; Feriha, C; Honderlick, P; Matar, G; Nordmann, P; Poirel, L; Yilmaz, M1
Ge, Y; Juan, C; Moya, B; Oliver, A; Pérez, JL; Zamorano, L1
De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM1
Chang, SC; Chen, YC; Hsia, KC; Li, SY; Liao, MH; Lin, YC; Sheng, WH1
Albuquerque, L; Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V1
Choi, JY; Ko, KS; Lee, MY; Park, YK; Peck, KR; Rhee, JY; Shin, JY; Song, JH1
Carmeli, Y; Chmelnitsky, I; Goren, MG; Navon-Venezia, S1
Eb, F; Guillon, H; Mammeri, H1
Al Naiemi, N; Debets-Ossenkopp, YJ; Nordmann, P; Poirel, L; Rodríguez-Martínez, JM1
Carmeli, Y; Chmelnitsky, I; Goren, MG; Leavitt, A; Navon-Venezia, S; Ofek, I1
Chang, FY; Chen, TL; Fung, CP; Huang, LY; Lu, PL; Siu, LK1
Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ1
Badal, RE; Bouchillon, SK; DiPersio, J; Hawser, SP; Hoban, DJ; Labombardi, VJ1
Abele-Horn, M; Claus, H; Elias, J; Engelhardt, K; Frosch, M; Joseph, B; Oesterlein, A; Schoen, C; Turnwald, D; Valenza, G1
Bini, L; Bonomo, RA; Borgianni, L; Docquier, JD; Frère, JM; Matagne, A; Rossolini, GM; Vandenameele, J1
Chang, WC; Chen, CP; Chen, TL; Cho, WL; Fung, CP; Kuo, SC; Lee, YT; Siu, LK1
Jiang, Y; Shen, P; Wei, Z; Yu, D; Yu, Y; Zhou, Z1
Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E1
Bertrand, X; Dehecq, B; Hocquet, D; Mariotte, P; Plésiat, P; Talon, D1
Asai, Y; Fujii, N; Maekawa, K; Mizuno, H; Mori, K; Sakawaki, E; Sawamoto, K; Tanno, K; Uemura, S; Yokota, S1
Cabot, G; Deng, L; Juan, C; Mark, BL; Moyá, B; Oliver, A; Reeve, TM; Vocadlo, DJ; Zamorano, L1
Harada, S; Ishii, Y; Saga, T; Tateda, K; Yamaguchi, K1
Bai, N; Cai, Y; Li, R; Liang, B; Liu, Y; Wang, R1
Collins, B; Cotter, PD; Curtis, N; Hill, C; Ross, RP1
Carattoli, A; García-Fernández, A; Giordano, A; Mancini, C; Miriagou, V; Papagiannitsis, CC; Venditti, M1
Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS1
Benvenuti, M; Calderone, V; Docquier, JD; Mangani, S; Menciassi, N; Rossolini, GM; Stoczko, M1
Chang, FY; Chen, TL; Fung, CP; Hsueh, PR; Ko, WC; Kuo, SC; Lee, YT; Siu, LK1
Lagrutta, E; Nordmann, P; Pham, J; Poirel, L; Taylor, P1
Bae, IK; Jeong, SH; Kim, J; Lee, K; Suh, B; Yong, D1
Hamprecht, A; Higgins, PG; Schneiders, T; Seifert, H1
Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Pulse, ME; Weiss, WJ1
Borgianni, L; Docquier, JD; Hanson, ND; Prandi, S; Rossolini, GM; Salden, L; Santella, G1
Anderson, KC; Kellogg, GE; Sarkar, A1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Du, XL; Huo, HR; Li, C; Li, J; Li, JT; Li, X; Ma, H; Sui, F; Sui, YP; Wang, WH; Wang, ZJ; Xin, JJ; Zhan, HD; Zhou, HY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bojkovic, J; Dean, CR; Dobler, M; Dzink-Fox, J; Glick, M; Hamann, LG; Kerrigan, J; Lanieri, L; Lenoir, F; Lilly, MD; Liu, E; Lu, Y; McKenney, D; Nunez, J; Osborne, C; Parker, DT; Patnaik, A; Peng, Y; Piizzi, G; Ranjitkar, S; Sprague, ER; Tommasi, R; Wang, B; Wang, H; Wattanasin, S; Xie, L; Yang, X; Yu, D1
Bermingham, A; Blais, J; Capka, V; Cariaga, T; Casarez, A; Colvin, R; Dean, CR; Fekete, A; Gong, W; Growcott, E; Guo, H; Jones, AK; Li, C; Li, F; Lin, X; Lindvall, M; Lopez, S; McKenney, D; Metzger, L; Moser, HE; Prathapam, R; Rasper, D; Reck, F; Rudewicz, P; Sethuraman, V; Shaul, J; Shen, X; Simmons, RL; Tang, D; Tashiro, K; Tjandra, M; Turner, N; Uehara, T; Vitt, C; Whitebread, S; Yifru, A; Zang, X; Zhu, Q1
Björkling, F; Bonke, G; Franzyk, H; Hansen, AM; Hogendorf, WFJ; Kongstad, KT; Nielsen, J; Nielsen, PE; Tomczak, M; Urbas, M; Zabicka, D1
Brunst, S; Burgers, LD; Frank, D; Fürst, R; Gobec, S; Martinelli, G; Proschak, A; Proschak, E; Rotter, MJ; Sosič, I; Weizel, L; Wichelhaus, TA1

Reviews

1 review(s) available for piperacillin and ceftazidime

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

166 other study(ies) available for piperacillin and ceftazidime

ArticleYear
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Animals; Anion Transport Proteins; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Cell Survival; Cephaloridine; Cephalosporins; In Vitro Techniques; Kidney; Kinetics; Oocytes; p-Aminohippuric Acid; Penicillin G; Rats; Recombinant Proteins; Xenopus laevis

1999
The synthesis and evaluation of 6-alkylidene-2'beta-substituted penam sulfones as beta-lactamase inhibitors.
    Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cloxacillin; Drug Therapy, Combination; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillin Resistance; Piperacillin; Structure-Activity Relationship; Sulfones

1999
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Novel Ambler class A beta-lactamase LAP-1 and its association with the plasmid-mediated quinolone resistance determinant QnrS1.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; Enterobacter cloacae; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Plasmids; Quinolones; Sequence Alignment

2007
Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests

2007
Detection of a new SHV-type extended-spectrum beta-lactamase, SHV-31, in a Klebsiella pneumoniae strain causing a large nosocomial outbreak in The Netherlands.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Anti-Bacterial Agents; beta-Lactamases; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Humans; Intensive Care Units; Isoelectric Focusing; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Netherlands; Plasmids

2007
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation

2007
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data

2007
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections

2007
First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Hydrolysis; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2007
SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillinase; Plasmids; Sequence Analysis, DNA

2007
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal

2007
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests

2007
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors

2007
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA

2007
Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Ethidium; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Minocycline; Molecular Sequence Data; Sequence Analysis, DNA; Tigecycline

2007
Biochemical characterization of PER-2 and genetic environment of blaPER-2.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Catalysis; Citrobacter freundii; Conjugation, Genetic; DNA, Bacterial; DNA, Recombinant; Enterobacteriaceae; Genes, Bacterial; Humans; Hydrolysis; Isoelectric Focusing; Kinetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Conformation; Protein Sorting Signals; Sequence Analysis, DNA

2007
blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3' conserved sequence.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Base Sequence; beta-Lactamases; DNA Transposable Elements; Evolution, Molecular; Genes, Bacterial; Humans; India; Integrons; Molecular Sequence Data; Pseudomonas aeruginosa; Russia; United States

2007
Polyamine effects on antibiotic susceptibility in bacteria.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Polyamines; Spermine; Staphylococcus aureus

2007
Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Bacteremia; Community-Acquired Infections; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Infectious Disease Transmission, Professional-to-Patient; Integrons; Microbial Sensitivity Tests; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Sequence Analysis, DNA; Treatment Outcome

2007
Extended-spectrum beta-lactamases of the CTX-M type now in Switzerland.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Hospitals, University; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Polymerase Chain Reaction; Prevalence; Switzerland

2007
Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cephalosporins; Chryseobacterium; Flavobacteriaceae Infections; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA

2007
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic

2007
Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Hospitals; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology

2007
Molecular epidemiology of imipenem-resistant Acinetobacter haemolyticus and Acinetobacter baumannii isolates carrying plasmid-mediated OXA-40 from a Portuguese hospital.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Acinetobacter; Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; beta-Lactamases; Cross Infection; Humans; Plasmids; Portugal

2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins

2007
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet

2007
Development of resistance in wild-type and hypermutable Pseudomonas aeruginosa strains exposed to clinical pharmacokinetic profiles of meropenem and ceftazidime simulated in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Ceftazidime; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Genotype; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Mutation; Phenotype; Porins; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Thienamycins

2007
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA

2007
An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Base Sequence; beta-Lactamases; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid

2007
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity

2007
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam

2007
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity

2007
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain

2007
Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Female; Greece; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids

2008
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity

2008
E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Enterobacter aerogenes; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Sequence Analysis, DNA; Serratia marcescens; Structure-Activity Relationship; Substrate Specificity

2008
Induction of L1 and L2 beta-lactamase production in Stenotrophomonas maltophilia is dependent on an AmpR-type regulator.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Enzyme Induction; Gene Expression Regulation, Bacterial; Genes, Regulator; Humans; Mutation; Stenotrophomonas maltophilia

2008
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA

2008
Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Base Sequence; beta-Lactamases; beta-Lactams; Cloning, Molecular; Colombia; DNA Transposable Elements; Greece; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA; United States

2008
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin

2008
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary

2008
Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Anti-Bacterial Agents; beta-Lactamases; Kinetics; Klebsiella pneumoniae

2008
Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; China; Conjugation, Genetic; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Hospitals, University; Humans; Hydrolysis; Intensive Care Units; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Serratia marcescens

2008
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Achromobacter denitrificans; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cloning, Molecular; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA

2008
IMP-15-producing Pseudomonas aeruginosa strain isolated in a U.S. medical center: a recent arrival from Mexico.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Hospitals; Humans; Imipenem; Kentucky; Male; Mexico; Pseudomonas aeruginosa; United States

2008
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Diamines; Escherichia coli; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Protein Biosynthesis; Pseudomonas aeruginosa; Structure-Activity Relationship

2008
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pectobacterium carotovorum; Phenotype; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid

2008
Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Bacterial Proteins; beta-Lactamases; Cross Infection; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Mexico; Models, Genetic; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections

2008
Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA

2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey

2008
Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Quinolones

2008
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Bulgaria; Catalysis; Germany; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA

2008
In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Acinetobacter baumannii; Amikacin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Microbial Sensitivity Tests; Minocycline; Tigecycline

2008
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity

2008
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States

2008
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalytic Domain; Cephalosporin Resistance; Crystallography, X-Ray; DNA Primers; DNA, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; France; Genes, Bacterial; Humans; Imipenem; Kinetics; Male; Models, Molecular; Mutation

2008
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins

2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids

2008
Plasmid-encoded carbapenem-hydrolyzing beta-lactamase OXA-48 in an imipenem-susceptible Klebsiella pneumoniae strain from Belgium.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Belgium; beta-Lactamases; beta-Lactams; Carbapenems; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Plasmids

2008
Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Amino Acid Substitution; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Female; Genes, Bacterial; Humans; Isoelectric Point; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Insertional; Recombinant Proteins

2008
Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Base Sequence; beta-Lactam Resistance; Carbapenems; DNA Primers; DNA, Bacterial; Doripenem; Fluoroquinolones; Genes, Bacterial; Humans; In Vitro Techniques; Meropenem; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins

2008
A plasmid-borne blaOXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Conjugation, Genetic; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Hospitals, University; Humans; Imipenem; Lebanon; Molecular Epidemiology; Molecular Sequence Data; Plasmids

2008
KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Citrobacter freundii; Conjugation, Genetic; DNA Primers; DNA, Bacterial; Enterobacteriaceae Infections; Escherichia coli K12; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Recombinant Proteins; Sequence Homology, Amino Acid

2008
Role of ampD homologs in overproduction of AmpC in clinical isolates of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Genetic Complementation Test; Humans; Molecular Sequence Data; N-Acetylmuramoyl-L-alanine Amidase; Pseudomonas aeruginosa; Pseudomonas Infections; RNA, Bacterial; Sequence Homology, Amino Acid

2008
In vitro activity of doripenem, a carbapenem for the treatment of challenging infections caused by gram-negative bacteria, against recent clinical isolates from the United States.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12

    Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; United States

2008
High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12

    Topics: Acetyltransferases; Anti-Bacterial Agents; Bacterial Proteins; China; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals, Teaching; Humans; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Prevalence; Quinolones

2008
First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Base Sequence; beta-Lactam Resistance; beta-Lactamases; Data Collection; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Integrons; Italy; Molecular Epidemiology; Molecular Sequence Data

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Anti-Bacterial Agents; beta-Lactamases; Enterobacter cloacae; Female; Humans; Liver Transplantation; Microbial Sensitivity Tests; Middle Aged; Pseudomonas putida; RNA, Ribosomal, 16S

2009
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Amino Acid Sequence; beta-Lactamases; Blotting, Southern; Ceftazidime; Cephalosporins; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shigella sonnei

2009
Sec- and Tat-dependent translocation of beta-lactamases across the Escherichia coli inner membrane.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Amoxicillin; beta-Lactamases; Cefotaxime; Ceftazidime; Cephalothin; Escherichia coli; Escherichia coli Proteins; Green Fluorescent Proteins; Microbial Sensitivity Tests; Piperacillin; Protein Transport

2009
Relative strengths of the class 1 integron promoter hybrid 2 and the combinations of strong and hybrid 1 with an active p2 promoter.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: beta-Lactamases; beta-Lactams; Integrons; Microbial Sensitivity Tests; Promoter Regions, Genetic; Pseudomonas aeruginosa

2009
Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Anti-Bacterial Agents; beta-Lactamases; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Hospitals; Klebsiella pneumoniae; Microbial Sensitivity Tests; Slovenia

2009
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence

2009
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Asparagine; Bacterial Proteins; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Serine

2009
Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Molecular Sequence Data; Plasmids; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic

2009
First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: beta-Lactamases; Brazil; Carbapenems; Klebsiella pneumoniae

2009
Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Resistance, Bacterial; Enzyme Inhibitors; Genetic Variation; Hydrolysis; Isoelectric Focusing; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phenotype; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction

2009
Genetic variability among ampC genes from acinetobacter genomic species 3.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain

2009
Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reproducibility of Results; Time Factors

2009
Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; beta-Lactamases; Burkholderia cepacia complex; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Hydrolysis; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2009
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporinase; Citrobacter freundii; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoelectric Point; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmids; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Substrate Specificity; Transformation, Genetic

2009
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18).
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping

2009
blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Base Sequence; beta-Lactamases; DNA Transposable Elements; Escherichia coli; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction

2009
Surveillance of carbapenem-resistant Pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: dissemination of KPC and IMP-18 beta-lactamases.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Outer Membrane Proteins; beta-Lactamases; Carbapenems; Child; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Humans; Infant; Male; Membrane Transport Proteins; Microbial Sensitivity Tests; Middle Aged; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa

2009
First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Austria; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA

2009
Extended-spectrum cephalosporinases in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporinase; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA

2009
Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acetylglucosamine; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Glycoside Hydrolases; Microbial Sensitivity Tests; Oximes; Phenylcarbamates; Pseudomonas aeruginosa

2009
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping

2009
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Cystic Fibrosis; DNA Repair; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Neutrophil Activation; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa

2009
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2009
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed

2009
Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Aztreonam; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporins; Escherichia coli Proteins; Protein Binding; Protein Structure, Secondary

2009
Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; China; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Imipenem; India; Klebsiella; Quinolones; Thailand

2009
Emergence of extended-spectrum beta-lactamase PER-1 in Proteus vulgaris and Providencia stuartii isolates from Algiers, Algeria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Algeria; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Imipenem; Microbial Sensitivity Tests; Piperacillin; Polymerase Chain Reaction; Proteus vulgaris; Providencia

2009
Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Klebsiella pneumoniae; Polymerase Chain Reaction

2009
Diversity of beta-lactamases produced by ceftazidime-resistant Pseudomonas aeruginosa isolates causing bloodstream infections in Brazil.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Carbapenems; Ceftazidime; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones

2009
Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Molecular Sequence Data; Poland

2009
New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Anti-Bacterial Agents; beta-Lactamases; Bulgaria; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data

2009
Novel genetic environment of the carbapenem-hydrolyzing beta-lactamase KPC-2 among Enterobacteriaceae in China.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Anti-Bacterial Agents; beta-Lactamases; Blotting, Southern; Carbapenems; China; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Microbial Sensitivity Tests; Polymerase Chain Reaction

2009
Involvement of pmrAB and phoPQ in polymyxin B adaptation and inducible resistance in non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Genotype; Microbial Sensitivity Tests; Polymyxin B; Promoter Regions, Genetic; Pseudomonas aeruginosa; Transcription Factors

2009
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid

2009
TEM-168, a heretofore laboratory-derived TEM beta-lactamase variant found in an Escherichia coli clinical isolate.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Base Sequence; beta-Lactamases; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data

2009
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: beta-Lactamases; Computational Biology; Escherichia coli; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Plasmids; United Kingdom

2009
Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Colistin; Cross Infection; Humans; Molecular Sequence Data; Pseudomonas aeruginosa

2009
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2009
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins

2009
OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Drug Resistance, Multiple, Bacterial; Escherichia coli; Imipenem; Meropenem; Molecular Sequence Data; Oxacillin; Penicillins; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Thienamycins

2009
In vivo efficacy of 1- and 2-gram human simulated prolonged infusions of doripenem against Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Administration Schedule; Female; Humans; Mice; Pseudomonas aeruginosa; Pseudomonas Infections

2009
ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Structure

2009
Susceptibilities of 23 Desulfovibrio isolates from humans.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Desulfovibrio; Fluoroquinolones; Humans; Metronidazole; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam

2009
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology

2010
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity

2010
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections

2010
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology

2010
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Algeria; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; beta-Lactams; Carbapenems; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Genome, Bacterial; Hospitals, Military; Imipenem; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Phenotype

2010
VIM-19, a metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli and Klebsiella pneumoniae.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction

2010
Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections

2010
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA

2010
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Taiwan

2010
Spread of OXA-48-encoding plasmid in Turkey and beyond.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Belgium; beta-Lactam Resistance; beta-Lactamases; Carbapenems; DNA Transposable Elements; Egypt; Enterobacteriaceae; Enterobacteriaceae Infections; France; Humans; Lebanon; Microbial Sensitivity Tests; Plasmids; Turkey

2010
Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Cross Infection; Humans; Intensive Care Units; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections

2010
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4

    Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic

2010
PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4

    Topics: Aeromonas; Animals; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Paris; Water Microbiology

2010
Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Aminoglycosides; beta-Lactamases; Carbapenems; Cephalosporins; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Taiwan

2010
Biochemical study of a new inhibitor-resistant beta-lactamase, SHV-84, produced by a clinical Escherichia coli strain.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: beta-Lactam Resistance; beta-Lactamases; Escherichia coli; Escherichia coli Proteins; Molecular Sequence Data

2010
KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Aged; beta-Lactamases; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Klebsiella Infections; Klebsiella pneumoniae; Male; Renal Dialysis; Republic of Korea

2010
Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Academic Medical Centers; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Israel; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Time Factors

2010
Characterization of CSP-1, a novel extended-spectrum beta-lactamase produced by a clinical isolate of Capnocytophaga sputigena.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Amino Acid Sequence; Amoxicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Capnocytophaga; Cephalosporins; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sepsis

2010
Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Integrons; Middle Aged; Molecular Sequence Data; Netherlands; Pseudomonas Infections; Pseudomonas stutzeri; Sequence Homology, Amino Acid; Substrate Specificity

2010
Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Phylogeny; Plasmids; Polymerase Chain Reaction

2010
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Acinetobacter; Acinetobacter Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporinase; Gene Transfer, Horizontal; Genes, Bacterial; Humans; In Vitro Techniques; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Taiwan

2010
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare

2010
Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART).
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Abdomen; Amikacin; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests

2010
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Drug Resistance, Bacterial; Germany; Hospitals, University; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections

2010
Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamases; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Protein Conformation; Protein Folding; Structure-Activity Relationship

2010
Contribution of a plasmid-borne blaOXA-58 gene with its hybrid promoter provided by IS1006 and an ISAba3-like element to beta-lactam resistance in acinetobacter genomic species 13TU.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carbapenems; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Promoter Regions, Genetic; Recombination, Genetic; Sequence Analysis, DNA; Species Specificity; Tazobactam

2010
Complete nucleotide sequence of Klebsiella pneumoniae multidrug resistance plasmid pKP048, carrying blaKPC-2, blaDHA-1, qnrB4, and armA.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Klebsiella pneumoniae; Models, Genetic; Molecular Sequence Data; Plasmids

2010
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed

2010
Nationwide investigation of extended-spectrum beta-lactamases, metallo-beta-lactamases, and extended-spectrum oxacillinases produced by ceftazidime-resistant Pseudomonas aeruginosa strains in France.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Cephalosporin Resistance; France; Humans; Microbial Sensitivity Tests; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections

2010
Acquisition of a transposon encoding extended-spectrum beta-lactamase SHV-12 by Pseudomonas aeruginosa isolates during the clinical course of a burn patient.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Adult; beta-Lactamases; Burns; DNA Transposable Elements; Female; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa

2010
NagZ inactivation prevents and reverts beta-lactam resistance, driven by AmpD and PBP 4 mutations, in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Ceftazidime; Microbial Sensitivity Tests; Mutation; N-Acetylmuramoyl-L-alanine Amidase; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction

2010
Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: beta-Lactamases; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Klebsiella pneumoniae; Molecular Sequence Data; Polymerase Chain Reaction; Proteus mirabilis; Salmonella typhimurium

2010
In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Mutation

2010
The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacitracin; Bacterial Proteins; beta-Lactam Resistance; Listeria monocytogenes; Nisin

2010
An ertapenem-resistant extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae clone carries a novel OmpK36 porin variant.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Electrophoresis, Polyacrylamide Gel; Ertapenem; Imipenem; Klebsiella pneumoniae; Meropenem; Molecular Sequence Data; Porins; Thienamycins

2010
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin

2010
High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: beta-Lactamases; Bradyrhizobium; Crystallography, X-Ray; Molecular Sequence Data; Protein Structure, Secondary; Substrate Specificity; Sulfonamides

2010
Emergence and Distribution of Plasmids Bearing the blaOXA-51-like gene with an upstream ISAba1 in carbapenem-resistant Acinetobacter baumannii isolates in Taiwan.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Blotting, Southern; Carbapenems; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Molecular Sequence Data; Plasmids; Taiwan

2010
Emergence of metallo-β-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Australia; beta-Lactamases; beta-Lactams; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Microbial Sensitivity Tests; Polymerase Chain Reaction

2010
Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Drug Resistance, Bacterial; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Porins; Reverse Transcriptase Polymerase Chain Reaction; Serratia Infections; Serratia marcescens; Thienamycins; Young Adult

2010
In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction

2010
Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Disease Models, Animal; Female; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Sepsis

2011
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Meropenem; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Thienamycins; United States

2011
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics

2012
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013
Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Carboplatin; Cell Line, Tumor; Cell Proliferation; Coumarins; Crystallography, X-Ray; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Molecular; Pyrans; Staphylococcus aureus

2015
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Female; Hep G2 Cells; Humans; K562 Cells; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship

2017
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
    Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; CHO Cells; Cricetulus; Drug Stability; Escherichia coli; Female; Humans; Meropenem; Mice; Microbial Sensitivity Tests; Molecular Structure; Monobactams; Pseudomonas aeruginosa; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thienamycins

2018
Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Anti-Bacterial Agents; Colistin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Peptide Nucleic Acids; Peptides; Solid-Phase Synthesis Techniques; Structure-Activity Relationship; Tigecycline

2019
Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.
    European journal of medicinal chemistry, 2022, Jan-15, Volume: 228

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroquinolines; Recombinant Proteins; Structure-Activity Relationship

2022