Page last updated: 2024-08-16

pioglitazone and riluzole

pioglitazone has been researched along with riluzole in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Benecke, R; Bogdahn, U; Dengler, R; Dreyhaupt, J; Dupuis, L; Fischer, W; Grehl, T; Grosskreutz, J; Heneka, MT; Hermann, A; Kassubek, J; Lindauer, E; Ludolph, AC; Meyer, T; Otto, M; Schrank, B; Steiner, F; Wessig, C; Winkler, AS; Zierz, S1
Dengler, R; Dieterlé, S; Dreyhaupt, J; Dupuis, L; El Oussini, H; Fischer, W; Grehl, T; Grosskreutz, J; Hermann, A; Kassubek, J; Ludolph, AC; Meyer, T; Scekic-Zahirovic, J; Sinniger, J; Spreux-Varoquaux, O; Van Den Bosch, L; Vercruysse, P; Witting, A; Zierz, S1

Reviews

1 review(s) available for pioglitazone and riluzole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for pioglitazone and riluzole

ArticleYear
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Aged; Amyotrophic Lateral Sclerosis; Animals; Anticonvulsants; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Mice; Middle Aged; Pioglitazone; Riluzole; Survival Rate; Thiazolidinediones

2012
Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis.
    Brain : a journal of neurology, 2016, Volume: 139, Issue:Pt 4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Female; Humans; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pioglitazone; Pro-Opiomelanocortin; Riluzole; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Thiazolidinediones

2016

Other Studies

5 other study(ies) available for pioglitazone and riluzole

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013