Compounds > pioglitazone
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pioglitazone and prostaglandin d2

pioglitazone has been researched along with prostaglandin d2 in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.66)18.2507
2000's37 (69.81)29.6817
2010's10 (18.87)24.3611
2020's3 (5.66)2.80

Authors

AuthorsStudies
Brun, RP; Chen, J; Evans, RM; Forman, BM; Spiegelman, BM; Tontonoz, P1
Hara, M; Hashimoto, N; Hashimoto, Y; Isoo, N; Kimura, S; Maekawa, H; Satoh, H; Togo, M; Tsukamoto, K; Watanabe, T1
Asano, M; Chisaki, K; Imuta, H; Iwasawa, K; Morita, T; Nakajima, T; Nakamura, F; Okuda, Y; Omata, M; Yamada, N1
Cook, JA; Gilkeson, GS; Halushka, PV; Morrow, JD; Oates, JC; Reilly, CM1
Banba, N; Hattori, Y; Hishinuma, A; Kakishita, H; Kasai, K; Matsumura, M; Motohashi, S; Sato, N1
Abe, I; Eto, K; Fujishima, M; Nakamura, Y; Ohya, Y1
Chlenski, A; Hattori, K; Hayashi, Y; Kita, A; Nakashiro, KI; Oyasu, R; Reddy, JK; Tamatani, T; Usuda, N1
Ando, K; Chiba, Y; Fujita, T; Ogita, T1
Inoue, K; Kawahito, Y; Kohno, M; Sano, H; Tsubouchi, Y; Yoshikawa, T; Yoshimura, R1
Ichiki, T; Iino, N; Takeda, K; Takeshita, A; Tokunou, T1
Furumatsu, T; Inoue, H; Kawai, A; Kunisada, T; Nishida, K; Takada, I; Yoshida, A1
Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS1
Ishii, H; Kanehara, H; Miyamori, I; Oida, K; Suzuki, J; Tohda, G1
Elstner, E; Fenner, MH; Liu, H; Possinger, K; Zang, C1
Kishimoto, C; Liu, Y; Liu, Z; Ma, A; Wang, Y; Yuan, Z; Zhang, J2
Kishimoto, C; Liu, Y; Liu, ZQ; Yuan, ZY; Zhang, JJ1
Ago, T; Iida, M; Iwase, M; Kitazono, T; Nakamura, U; Ueta, M; Wakisaka, M; Yoshinari, M1
Baba, T; Hayashi, Y; Katoh, T; Midorikawa, S; Onozaki, A; Sanada, H; Watanabe, T1
Elstner, E; Facklam, M; Fenner, MH; Liu, H; Phillip Koeffler, H; Posch, MG; Possinger, K; Ruthardt, M; Waechter, M; Zang, C1
Kishimoto, C; Liu, Y; Liu, Z; Ma, A; Yuan, Z; Zhang, J1
Bängeroth, K; Elstner, E; Eucker, J; Heider, U; Jakob, C; Krebbel, H; Possinger, K; Sezer, O; Zang, C; Zavrski, I1
Chen, J; Chen, Q; Jiang, H; Shen, J; Shen, X; Sun, T1
Arai, H; Chun, TH; Doi, K; Fukunaga, Y; Inoue, M; Itoh, H; Masatsugu, K; Nakao, K; Saito, T; Sakaguchi, S; Sawada, N; Tanaka, T; Yamashita, J1
Higashihara, H; Imamoto, E; Kokura, S; Naito, Y; Ueda, M; Yoshida, N; Yoshikawa, T1
Hisasue, S; Itoh, N; Kitamura, H; Masumori, N; Takahashi, A; Tsukamoto, T; Uchida, K; Yuan, J1
Artwohl, M; Baumgartner-Parzer, SM; Freudenthaler, A; Fürnsinn, C; Hölzenbein, T; Huttary, N; Waldhäusl, WK1
Maeda, T; Makino, N; Oyama, J; Satoh, S; Sugano, M1
Horiuchi, A; Kagechika, H; Kamisaka, Y; Nakatsu, M; Okuma, E; Saeki, K; Uemura, I; Yasuda, K; Yasugi, E; Yuo, A1
Horinaka, M; Kouhara, J; Nakata, S; Sakai, T; Shiraishi, T; Wakada, M; Yoshida, T1
Elstner, E; Eucker, J; Heider, U; Jakob, C; Kaiser, M; Krebbel, H; Sezer, O; Sterz, J; Zang, C; Zavrski, I1
Fujii, H; Hirota, K; Kimura, H; Kimura, N; Li, X; Sugimoto, H; Takahashi, N; Yoshida, H1
Birnbaum, Y; Huang, MH; Lin, Y; Manickavasagam, S; Nishi, SP; Perez-Polo, JR; Uretsky, BF; Ye, Y1
Fang, NY; Gao, PJ; Guo, SJ; Han, WQ; Shen, WL; Wu, LY; Zhang, J; Zhu, DL1
Choi, IK; Kim, JS; Kim, YH; Seo, JH1
Fujii, H; Ishihara, S; Kimura, H; Li, X; Okada, T; Takahashi, N; Torii, K; Yoshida, H1
Dhar, DK; Nagasue, N; Ono, T; Tachibana, M; Tanaka, T; Yamamoto, Y; Yamanoi, A1
Li, A; Li, H; Liu, J; Xia, Q; Xiu, R; Zhang, J; Zhang, Q1
Bernardo, A; Bianchi, D; Magnaghi, V; Minghetti, L1
Cheng, C; He, X; Hu, L; Ji, H; Li, X; Liu, F; Qian, J; Shen, A; Yan, M; Zhang, F; Zhang, L1
Chang, R; Chang, YW; Dong, SH; Hwangbo, Y; Jang, JY; Kim, BH; Kim, HJ; Kim, KY; Kim, YI; Shim, J1
Liao, K; Xiao, Y; Yao, W; Yuan, T1
Cook, JL; Hanks, BC; Kuroki, K; Stoker, AM1
Liu, YX; Wu, SM; Ye, P1
Douglas, JC; Drew, PD; Han, L; Kane, CJ; Phelan, KD; Smith, RR; Xie, J1
Bothwell, AL; Choi, JM; Kawikova, I; Kulkarni, S; Lorber, MI; Manes, TD; Pober, JS; Qin, L; Rodriguez, FC; Tellides, G; Tobiasova, Z; Yi, T; Zhang, L1
Hajri, T; Tao, H1
Bernardo, A; De Nuccio, C; De Simone, R; Magnaghi, V; Mancuso, E; Minghetti, L; Visentin, S1
Chima, R; Kaplan, J; Nowell, M; Zingarelli, B1
Ben-Harosh, Y; Birk, R; Danino, H; Fogel, C; Kadir, R; Naor, RP; Salem, H1
Bogacka, I; Jastrzębski, JP; Kunicka, Z; Kurzyńska, A; Mierzejewski, K; Paukszto, Ł1
Bogacka, I; Golubska, M; Kunicka, Z; Kurzyńska, A; Mierzejewski, K1
Bogacka, I; Golubska, M; Jastrzębski, JP; Kunicka, Z; Kurzyńska, A; Makowczenko, KG; Mierzejewski, K; Paukszto, Ł1

Other Studies

53 other study(ies) available for pioglitazone and prostaglandin d2

ArticleYear
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.
    Cell, 1995, Dec-01, Volume: 83, Issue:5

    Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Carrier Proteins; Cell Differentiation; Complement Factor D; DNA-Binding Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Molecular Sequence Data; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Pioglitazone; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Serine Endopeptidases; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation

1995
Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARgamma on vascular endothelial function.
    Biochemical and biophysical research communications, 1999, Jan-27, Volume: 254, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Chromans; Endothelin-1; Endothelium, Vascular; Hypoglycemic Agents; Insulin; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

1999
Troglitazone and pioglitazone attenuate agonist-dependent Ca2+ mobilization and cell proliferation in vascular smooth muscle cells.
    British journal of pharmacology, 1999, Volume: 128, Issue:3

    Topics: Animals; Calcium; Calcium Channels, L-Type; Cell Division; Cell Line; Chromans; Hypoglycemic Agents; Membrane Potentials; Muscle, Smooth, Vascular; Pioglitazone; Platelet-Derived Growth Factor; Prostaglandin D2; Rats; Thiazoles; Thiazolidinediones; Troglitazone; Vasopressins

1999
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Feb-01, Volume: 164, Issue:3

    Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Female; Glomerular Mesangium; Isoenzymes; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisomes; Pioglitazone; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors

2000
15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6

    Topics: Anticholesteremic Agents; Arsenites; Bucladesine; Cells, Cultured; Chromans; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetal Proteins; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoglycemic Agents; Ligands; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pioglitazone; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sodium Compounds; Thiazoles; Thiazolidinediones; Thyroglobulin; Thyroid Gland; Thyrotropin; Transcription Factors; Troglitazone

2000
Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle.
    European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1

    Topics: Analysis of Variance; Animals; Barium; Calcium; Chromans; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Humans; Insulin Resistance; Ion Channels; Isoxazoles; Membrane Potentials; Muscle, Smooth, Vascular; Pioglitazone; Potassium Channels; Prostaglandin D2; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone

2001
Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells.
    The American journal of pathology, 2001, Volume: 159, Issue:2

    Topics: Aged; Blotting, Western; Cell Division; Cell Line; Chromans; Dose-Response Relationship, Drug; Humans; Immunologic Factors; Ligands; Male; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transfection; Troglitazone; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urothelium

2001
PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells.
    Biochemical and biophysical research communications, 2001, Aug-24, Volume: 286, Issue:3

    Topics: Animals; Arteriosclerosis; Cattle; Cells, Cultured; Chromans; Drug Antagonism; Endothelium; Immunohistochemistry; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone; Tumor Necrosis Factor-alpha

2001
Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists.
    Biochemical and biophysical research communications, 2001, Sep-28, Volume: 287, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Renal Cell; Cell Division; Chromans; Coloring Agents; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Immunohistochemistry; Immunologic Factors; Kidney Neoplasms; Ligands; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured; Up-Regulation

2001
15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.
    The Journal of biological chemistry, 2001, Dec-28, Volume: 276, Issue:52

    Topics: Androstadienes; Animals; Cells, Cultured; Chromans; Enzyme Activation; Enzyme Inhibitors; Immunologic Factors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pioglitazone; Prostaglandin D2; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Thymidine; Transcription Factors; Troglitazone; Wortmannin

2001
Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma.
    British journal of cancer, 2002, Apr-22, Volume: 86, Issue:8

    Topics: Apoptosis; Cell Cycle; Cell Division; Cell Survival; Chondrosarcoma; Flow Cytometry; Humans; Male; Microscopy, Electron; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured

2002
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:9

    Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2002
Thrombomodulin expression by THP-1 but not by vascular endothelial cells is upregulated by pioglitazone.
    Thrombosis research, 2002, Nov-25, Volume: 108, Issue:4

    Topics: Antibodies, Monoclonal; Blotting, Northern; CD4 Antigens; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Endothelium, Vascular; Flow Cytometry; Gene Expression Regulation; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Thrombomodulin; Thromboplastin; Transcription Factors; Tumor Cells, Cultured; Up-Regulation

2002
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro.
    Breast cancer research and treatment, 2003, Volume: 79, Issue:1

    Topics: Breast Neoplasms; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nuclear Proteins; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinases; Transcription Factors; Tretinoin; Tumor Cells, Cultured

2003
Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis.
    Cardiovascular research, 2003, Sep-01, Volume: 59, Issue:3

    Topics: Animals; Autoimmune Diseases; Hypoglycemic Agents; Interleukin-1; Models, Animal; Myocarditis; Pioglitazone; Prostaglandin D2; Rats; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors

2003
[Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity].
    Zhonghua yi xue za zhi, 2003, Dec-10, Volume: 83, Issue:23

    Topics: Animals; Autoimmune Diseases; Immunosuppressive Agents; Myocarditis; Pioglitazone; Prostaglandin D2; Rats; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Swine; T-Lymphocytes; Thiazolidinediones; Transcription Factors

2003
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose.
    Kidney international, 2004, Volume: 65, Issue:3

    Topics: Actins; Angiotensin II; Animals; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; DNA, Antisense; Enzyme Inhibitors; Flavonoids; Gene Expression; Glomerular Mesangium; Glucose; Hypoglycemic Agents; Indomethacin; Ligands; Pioglitazone; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Vasoconstrictor Agents

2004
Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: inhibitory effects of thiazolidinedione.
    Biochemical and biophysical research communications, 2004, Apr-23, Volume: 317, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression; Glomerular Mesangium; Glucose; Male; Phenanthridines; Pioglitazone; Prostaglandin D2; Protein Kinase Inhibitors; Rats; Rats, Inbred OLETF; Rats, Sprague-Dawley; RNA, Messenger; Thiazolidinediones; Thymidine; Vascular Endothelial Growth Factor A

2004
Peroxisome proliferator-activated receptor gamma ligands induce growth inhibition and apoptosis of human B lymphocytic leukemia.
    Leukemia research, 2004, Volume: 28, Issue:4

    Topics: Adolescent; Apoptosis; Blotting, Western; Burkitt Lymphoma; Cell Cycle; Cell Division; Cell Line, Tumor; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Situ Nick-End Labeling; Ligands; Male; Middle Aged; Pioglitazone; Polymorphism, Single-Stranded Conformational; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Thiazolidinediones; Transcription Factors

2004
Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:6

    Topics: Animals; Autoimmune Diseases; Cells, Cultured; Dose-Response Relationship, Drug; Ligands; Myocarditis; Myocytes, Cardiac; Pioglitazone; Prostaglandin D2; Rats; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Swine; T-Lymphocytes; Thiazolidinediones; Transcription Factors

2004
Ligands of peroxisome proliferator-activated receptor gamma induce apoptosis in multiple myeloma.
    Anti-cancer drugs, 2004, Volume: 15, Issue:10

    Topics: Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Humans; Ligands; Multiple Myeloma; Pioglitazone; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2004
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
    Analytical biochemistry, 2004, Dec-15, Volume: 335, Issue:2

    Topics: alpha-Galactosidase; Anilides; Cells, Cultured; Chromans; CREB-Binding Protein; Drug Evaluation, Preclinical; Genes, Reporter; Indomethacin; Ligands; Nuclear Proteins; Oxazoles; Pioglitazone; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Thiazolidinediones; Trans-Activators; Troglitazone; Two-Hybrid System Techniques; Tyrosine; Yeasts

2004
Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor gamma for monocyte recruitment and endothelial regeneration.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Alitretinoin; Angioplasty, Balloon; Animals; Aorta; Arteriosclerosis; Binding, Competitive; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CCL2; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression Regulation; Humans; Macrophages; Male; Monocytes; Pioglitazone; PPAR gamma; Prostaglandin D2; Rabbits; Receptors, CCR2; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazolidinediones; Time Factors; Tretinoin; Troglitazone; Vascular Endothelial Growth Factor A; Wound Healing

2005
Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells.
    Redox report : communications in free radical research, 2004, Volume: 9, Issue:6

    Topics: Cell Hypoxia; Humans; I-kappa B Proteins; Interleukin-8; Monocytes; NF-kappa B; NF-KappaB Inhibitor alpha; Oligopeptides; Oxygen; Pioglitazone; PPAR gamma; Prostaglandin D2; Thiazolidinediones; Transfection; U937 Cells

2004
Cardioprotective effects of peroxisome proliferator activated receptor gamma activators on acute myocarditis: anti-inflammatory actions associated with nuclear factor kappaB blockade.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:9

    Topics: Acute Disease; Animals; Autoimmune Diseases; Cardiotonic Agents; Cytokines; Gene Expression Regulation; Myocarditis; Myosins; NF-kappa B; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Inbred Lew; RNA, Messenger; Thiazolidinediones

2005
Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma.
    Urology, 2005, Volume: 65, Issue:3

    Topics: Carcinoma, Renal Cell; Cell Division; Dose-Response Relationship, Drug; Humans; Kidney Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; Thiazolidinediones; Tumor Cells, Cultured

2005
Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells.
    Thrombosis and haemostasis, 2005, Volume: 93, Issue:5

    Topics: Aorta; Apoptosis; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Chaperonin 60; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Endothelium, Vascular; Enzyme Activation; Humans; Hypoglycemic Agents; Ligands; Microscopy, Phase-Contrast; Mitochondria; Pioglitazone; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rosiglitazone; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha; von Willebrand Factor

2005
Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia.
    Cell biochemistry and biophysics, 2006, Volume: 44, Issue:1

    Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Cell Hypoxia; Cells, Cultured; Collagen Type I; Collagen Type III; Electrophoretic Mobility Shift Assay; Fibroblasts; Gene Expression; Ligands; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle Cells; Myocardial Reperfusion Injury; Myocardium; Natriuretic Peptide, Brain; NF-kappa B; Oxygen; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; RNA, Messenger; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1

2006
Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.
    Development, growth & differentiation, 2006, Volume: 48, Issue:3

    Topics: Adipocytes; Anilides; Benzoates; Biphenyl Compounds; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Fatty Acid-Binding Proteins; Humans; Ligands; Lipids; Myeloid Cells; Pioglitazone; PPAR gamma; Prostaglandin D2; Thiazolidinediones; Tretinoin; Triglycerides; Tumor Cells, Cultured; Up-Regulation

2006
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Gene Expression; Humans; Jurkat Cells; Membrane Glycoproteins; Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA Stability; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2006
Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma.
    Anti-cancer drugs, 2006, Volume: 17, Issue:7

    Topics: Annexin A5; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Ligands; Lymphoma, Mantle-Cell; Pioglitazone; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2006
Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-gamma in human proximal renal tubular cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:4

    Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Cyclic N-Oxides; Gene Expression Regulation; Humans; Hypoglycemic Agents; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Diseases; Kidney Tubules, Proximal; Oligonucleotide Array Sequence Analysis; Pioglitazone; PPAR gamma; Prostaglandin D2; RNA, Messenger; Spin Labels; Thiazolidinediones; Tumor Necrosis Factor-alpha

2007
Activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) by atorvastatin is mediated by 15-deoxy-delta-12,14-PGJ2.
    Prostaglandins & other lipid mediators, 2007, Volume: 84, Issue:1-2

    Topics: Animals; Atorvastatin; CD36 Antigens; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Models, Biological; Models, Chemical; Myocardium; Pioglitazone; PPAR gamma; Prostaglandin D2; Pyrroles; Rats; Thiazolidinediones; Transcription Factors

2007
Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Acetylcysteine; Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Connective Tissue; Dose-Response Relationship, Drug; Fibroblasts; Free Radical Scavengers; Male; NF-kappa B; Oxidative Stress; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Thiazolidinediones; Time Factors; Transcription Factor AP-1

2008
PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo.
    Investigational new drugs, 2008, Volume: 26, Issue:3

    Topics: Animals; beta Catenin; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, APC; HT29 Cells; Humans; Ligands; Mice; Mice, Nude; Mutation; Pioglitazone; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-myc; Thiazolidinediones; Xenograft Model Antitumor Assays

2008
A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:8

    Topics: Cell Hypoxia; Cells, Cultured; Flavonoids; Genistein; Humans; Inflammation; Kidney Tubules, Proximal; MAP Kinase Kinase 1; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; Prostaglandin D2; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Thiazolidinediones; Tumor Necrosis Factor-alpha

2008
Role of peroxisome proliferator-activated receptor-gamma (PPARgamma) during liver regeneration in rats.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Hepatectomy; Hypoglycemic Agents; Liver; Liver Regeneration; Male; Models, Animal; Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Thiazolidinediones

2008
Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNF-alpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:3

    Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Chemokines, CXC; Electrophoretic Mobility Shift Assay; Hydrogen Peroxide; Immunologic Factors; Lipopolysaccharides; Myocytes, Cardiac; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells.
    Journal of neuropathology and experimental neurology, 2009, Volume: 68, Issue:7

    Topics: Active Transport, Cell Nucleus; Anilides; Animals; Antioxidants; Catalase; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Homeostasis; Oligodendroglia; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; Stem Cells; Superoxide Dismutase; Thiazolidinediones

2009
Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells.
    Journal of neuroimmunology, 2010, Jan-25, Volume: 218, Issue:1-2

    Topics: Anilides; Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Down-Regulation; Enzyme Inhibitors; Fluorescent Antibody Technique; Lipopolysaccharides; Myeloid Differentiation Factor 88; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Schwann Cells; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 4

2010
The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells.
    International journal of oncology, 2010, Volume: 36, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Hepatitis B virus; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Liver Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Thiazolidinediones

2010
3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway.
    The FEBS journal, 2010, Volume: 277, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Chromans; Male; Mice; Pioglitazone; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Zucker; Thiazolidinediones; Troglitazone

2010
Evaluation of anti-inflammatory and chondroprotective effects of peroxisome proliferator-activated receptor gamma agonists in cartilage and synovial explants from dogs.
    American journal of veterinary research, 2010, Volume: 71, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Coculture Techniques; Dinoprostone; Dogs; Interleukin-1beta; Nitric Oxide; Pioglitazone; PPAR gamma; Prostaglandin D2; Synovial Membrane; Thiazolidinediones; Time Factors

2010
[The role of peroxisome proliferator-activated receptor gamma in proliferation of cardiac non myocytes].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2006, Volume: 22, Issue:2

    Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Heart; Male; Myocardium; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; Thiazolidinediones

2006
Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists.
    Brain, behavior, and immunity, 2011, Volume: 25 Suppl 1

    Topics: Analysis of Variance; Animals; Brain; Cell Count; Cell Survival; Cells, Cultured; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Mice; Mice, Inbred C57BL; Microglia; Neurons; Pioglitazone; PPAR gamma; Pregnancy; Prostaglandin D2; Thiazolidinediones

2011
Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells.
    Circulation, 2011, Jul-12, Volume: 124, Issue:2

    Topics: Adoptive Transfer; Anilides; Animals; Arteries; Cell Movement; Cell Proliferation; Cytokines; Graft Rejection; Humans; Hypoglycemic Agents; Immunologic Memory; Isoantigens; Mice; Mice, SCID; Pioglitazone; PPAR gamma; Prostaglandin D2; Superantigens; T-Lymphocytes; Thiazolidinediones; Transplantation, Heterologous; Transplantation, Homologous

2011
Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists.
    Biochemical pharmacology, 2011, Dec-15, Volume: 82, Issue:12

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Gene Expression Regulation; Humans; Hypolipidemic Agents; Mice; Pioglitazone; PPAR gamma; Prostaglandin D2; Receptors, LDL; Thiazolidinediones

2011
Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.
    Journal of neuropathology and experimental neurology, 2011, Volume: 70, Issue:10

    Topics: Aniline Compounds; Animals; Animals, Newborn; Biological Clocks; Calcium; Cell Differentiation; Cells, Cultured; Electron Transport Complex IV; Gene Expression Regulation; Membrane Potential, Mitochondrial; Mitochondria; Myelin Basic Protein; Oligodendroglia; Organometallic Compounds; Pioglitazone; PPAR gamma; Prosencephalon; Prostaglandin D2; Rats; Rats, Wistar; Stem Cells; Thiazolidinediones; Xanthenes

2011
Pioglitazone reduces inflammation through inhibition of NF-κB in polymicrobial sepsis.
    Innate immunity, 2014, Volume: 20, Issue:5

    Topics: Adipokines; Animals; Cytokines; Hypoglycemia; Hypoglycemic Agents; I-kappa B Proteins; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pioglitazone; PPAR gamma; Prostaglandin D2; Sepsis; Thiazolidinediones

2014
PPARγ regulates exocrine pancreas lipase.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:12 Pt A

    Topics: Animals; Base Sequence; Binding Sites; Cell Line; Computational Biology; Down-Regulation; Gene Expression; Lipase; Pancreas; Pancreas, Exocrine; Pioglitazone; PPAR gamma; Promoter Regions, Genetic; Prostaglandin D2; Rats; Sequence Alignment; Thiazolidinediones; Transcription, Genetic; Transcriptional Activation; Up-Regulation

2016
Transcriptome analysis of porcine endometrium after LPS-induced inflammation: effects of the PPAR-gamma ligands in vitro†.
    Biology of reproduction, 2021, 01-04, Volume: 104, Issue:1

    Topics: Alternative Splicing; Animals; Benzamides; Endometrium; Female; Gene Expression Profiling; Inflammation; Lipopolysaccharides; Pioglitazone; PPAR gamma; Prostaglandin D2; Pyridines; Swine

2021
PPARγ ligands modulate the immune response mediators in the pig myometrium - An in vitro study.
    Animal reproduction science, 2021, Volume: 234

    Topics: Animals; Antineoplastic Agents; Benzamides; Cytokines; Female; Gene Expression Regulation; Hypoglycemic Agents; Immunity; Myometrium; Pioglitazone; PPAR gamma; Pregnancy; Prostaglandin D2; Pyridines; Swine; Tissue Culture Techniques

2021
PPARγ regulates the expression of genes involved in the DNA damage response in an inflamed endometrium.
    Scientific reports, 2022, 03-07, Volume: 12, Issue:1

    Topics: Animals; DNA Damage; Endometrium; Female; Inflammation; Ligands; Lipopolysaccharides; Pioglitazone; PPAR gamma; Prostaglandin D2; RNA, Long Noncoding; Swine; Thiazolidinediones

2022