Compounds > pioglitazone

Page last updated: 2024-08-16

pioglitazone and morphine

pioglitazone has been researched along with morphine in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	11 (91.67)	24.3611
2020's	1 (8.33)	2.80

Authors

Authors	Studies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Almasi-Nasrabadi, M; Babaei, R; Dehpour, AR; Javadi-Paydar, M; Mahdavian, S; Norouzi, A; Sharifian, M	1
Azarfardian, A; Charkhpour, M; Ghanbarzadeh, S; Ghavimi, H; Hassanzadeh, K; Maleki-Dizaji, N	1
Azarfardian, A; Charkhpour, M; Ghasami, S; Ghavimi, H; Hassanzadeh, K; Maleki-Dizaji, N; Zolali, E	1
Ciccocioppo, R; de Guglielmo, G; Demopulos, G; Gaitanaris, G; Kallupi, M; Scuppa, G; Stopponi, S	1
Ciccocioppo, R; Cippitelli, A; Damadzic, R; de Guglielmo, G; De Luca, MA; Demopulos, G; Gaitanaris, G; Giordano, A; Heilig, M; Kallupi, M; Li, HW; Melis, M; Niswender, K; Senzacqua, M; Somaini, L; Tapocik, J	1
Arami, S; Charkhpour, M; Ghasemi, S; Ghavimi, H; Hamishehkar, H; Hassanzadeh, K; Mesgari, M	1
Charkhpour, M; Ghanbarzadeh, S; Ghavimi, H; Hassanzadeh, K; Khorrami, A; Mesgari, M; Yousefi, B	1
Ciccocioppo, R; de Guglielmo, G; Demopulos, G; Gaitanaris, G; Kallupi, M; Scuppa, G	1
Donahue, RR; Laird, DE; Oliveira, MCG; Santos, DFS; Taylor, BK	1

Reviews

1 review(s) available for pioglitazone and morphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for pioglitazone and morphine

Article	Year
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Involvement of nitric oxide in pioglitazone memory improvement in morphine-induced memory impaired mice. Pharmacology, biochemistry, and behavior, 2012, Volume: 103, Issue:2 Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Fear; Male; Maze Learning; Memory Disorders; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pioglitazone; Thiazolidinediones	2012
Acute administration of pioglitazone attenuates morphine withdrawal syndrome in rat: a novel role of pioglitazone. Drug research, 2015, Volume: 65, Issue:3 Topics: Analgesics, Opioid; Anilides; Animals; Male; Morphine; Morphine Dependence; Naloxone; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Thiazolidinediones	2015
Pioglitazone prevents morphine antinociception tolerance and withdrawal symptoms in rats. Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:9 Topics: Analgesics, Opioid; Anilides; Animals; Behavior, Animal; Drug Tolerance; Male; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pioglitazone; PPAR gamma; Rats, Wistar; Substance Withdrawal Syndrome; Thiazolidinediones	2014
Analgesic tolerance to morphine is regulated by PPARγ. British journal of pharmacology, 2014, Volume: 171, Issue:23 Topics: Analgesics, Opioid; Anilides; Animals; Body Temperature; Drug Tolerance; Hot Temperature; Male; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Pain; Pioglitazone; PPAR gamma; Thiazolidinediones	2014
PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:4 Topics: Anilides; Animals; Conditioning, Operant; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Heroin; Hypoglycemic Agents; Male; Mice, Transgenic; Morphine; Narcotics; Nucleus Accumbens; Pioglitazone; PPAR gamma; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration; Synaptic Transmission; Thiazolidinediones; Time Factors; Ventral Tegmental Area	2015
Pioglitazone prevents morphine antinociceptive tolerance via ameliorating neuroinflammation in rat cerebral cortex. Pharmacological reports : PR, 2015, Volume: 67, Issue:1 Topics: Administration, Oral; Analgesics, Opioid; Anilides; Animals; Cerebral Cortex; Cytokines; Drug Tolerance; Encephalitis; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Morphine; NF-kappa B; Pain Measurement; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Thiazolidinediones	2015
Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord. Journal of biomedical science, 2015, Sep-23, Volume: 22 Topics: Animals; Cytokines; Drug Tolerance; Inflammation; Lumbar Vertebrae; Male; Morphine; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Spinal Cord; Thiazolidinediones	2015
Pioglitazone attenuates the opioid withdrawal and vulnerability to relapse to heroin seeking in rodents. Psychopharmacology, 2017, Volume: 234, Issue:2 Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Conditioning, Operant; Heroin; Male; Mice; Morphine; Narcotics; Opioid-Related Disorders; Pioglitazone; Rats; Rats, Wistar; Recurrence; Rodentia; Self Administration; Substance Withdrawal Syndrome; Thiazolidinediones	2017
The PPARγ agonist pioglitazone produces a female-predominant inhibition of hyperalgesia associated with surgical incision, peripheral nerve injury, and painful diabetic neuropathy. Neuropharmacology, 2022, 03-01, Volume: 205 Topics: Analgesics; Animals; Diabetic Neuropathies; Disease Models, Animal; Female; Hyperalgesia; Male; Mice; Morphine; Neuralgia; Nociceptive Pain; Pain, Postoperative; Peripheral Nerve Injuries; Pioglitazone; PPAR gamma; Pyruvaldehyde; Sex Characteristics	2022