Compounds > pioglitazone

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pioglitazone and isoproterenol

pioglitazone has been researched along with isoproterenol in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (16.67)	18.2507
2000's	3 (25.00)	29.6817
2010's	7 (58.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Bleasdale, JE; Jacob, CS; Sizer, KM; Smith, CL; Swanson, ML	2
Antoine, B; Beale, EG; Chauvet, G; Forest, C; Quette, J; Tordjman, J	1
Cachofeiro, V; Davel, AP; Fukuda, LE; Lahera, V; Lopes, LR; Rossoni, LV; Verissimo-Filho, S	1
Abd-Elrahman, KS; Abdel-Galil, AG; El-Gowelli, HM; El-Gowilly, SM; El-Mas, MM; Saad, EI	1
Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA	1

Reviews

1 review(s) available for pioglitazone and isoproterenol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for pioglitazone and isoproterenol

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism. Molecular and cellular endocrinology, 1994, Volume: 103, Issue:1-2 Topics: 1-Phosphatidylinositol 4-Kinase; 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cyclic AMP; Enzyme Activation; Hypoglycemic Agents; Immunosorbent Techniques; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Kinetics; Male; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Thiazoles; Thiazolidinediones; Tyrosine	1994
Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism. Molecular and cellular endocrinology, 1994, Volume: 102, Issue:1-2 Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cyclic AMP; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Pioglitazone; Precipitin Tests; Thiazoles; Thiazolidinediones	1994
Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells. The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21 Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Cells, Cultured; Cyclic AMP; Enzyme Activation; Esterification; Fatty Acids; Female; Gene Expression; Glycerol; Glycerol Kinase; Homeostasis; Hypoglycemic Agents; Isoproterenol; Lipid Metabolism; Lipolysis; Phosphoenolpyruvate Carboxykinase (GTP); Pioglitazone; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Viscera	2003
Fenofibrate and pioglitazone do not ameliorate the altered vascular reactivity in aorta of isoproterenol-treated rats. Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:5 Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Fenofibrate; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Potassium Chloride; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Superoxide Dismutase; Thiazolidinediones; Vasoconstriction; Vasoconstrictor Agents; Vasodilation	2008
PPARγ dependence of cyclosporine-isoprenaline renovascular interaction: roles of nitric oxide synthase and heme oxygenase. Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:2 Topics: Animals; Cyclosporine; Drug Interactions; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Isoproterenol; Kidney; Male; Nitric Oxide Synthase; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thiazolidinediones; Vasodilation	2011
Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:5 Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Diet, High-Fat; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Heart Rate; Heart Ventricles; Hypoglycemic Agents; Insulin Resistance; Isoproterenol; Male; Myocardial Infarction; Organ Size; Overweight; Pioglitazone; Random Allocation; Rats, Wistar; Receptor for Advanced Glycation End Products; Thiazolidinediones	2016