Page last updated: 2024-08-16

pindolol and xamoterol

pindolol has been researched along with xamoterol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's5 (27.78)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Mehlsen, J; Trap-Jensen, J2
Böhm, M; Erdmann, E; Mittmann, C; Schwinger, RH1
Cruickshank, JM; Graham, BR; Hayes, Y; Jones, A; Lewis, AD; Lui, JB; Prichard, BN; Renondin, JC; Tomlinson, B1
Barnett, DB; Haworth, D; Kowalski, MT; Lu, X; Thomson, DS1
Hadfield, SE; Slee, SJ; Snow, HM1
Charlier, AA; Debaisieux, JC; Pouleur, H; Rousseau, MF; Van Eyll, C1
Malta, E; Mian, MA; Raper, C1
Hasebe, N; Honda, H; Kawamura, Y; Kimura, T; Obara, A; Onodera, S; Yahara, O; Yamashita, H1
Cavero, I; Hicks, PE; Langer, SZ; Lefevre-Borg, F; Manoury, P1
Hattori, Y; Kanno, M; Nakao, Y; Sakuma, I1
Beer, M; Hacker, S; Poat, J; Stahl, SM1
Mehlsen, J; Stadeager, C; Trap-Jensen, J1

Trials

2 trial(s) available for pindolol and xamoterol

ArticleYear
Selective beta-adrenoceptor partial agonist effects of pindolol and xamoterol on skeletal muscle assessed by plasma creatine kinase changes in healthy subjects.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Aged; Blood Pressure; Creatine Kinase; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Muscle Contraction; Muscles; Pindolol; Propanolamines; Xamoterol

1990
Xamoterol, a new selective beta-1-adrenoceptor partial agonist, in the treatment of postural hypotension.
    Acta medica Scandinavica, 1986, Volume: 219, Issue:2

    Topics: Adrenergic beta-Agonists; Aged; Clinical Trials as Topic; Female; Hemodynamics; Humans; Hypotension, Orthostatic; Male; Middle Aged; Pindolol; Propanolamines; Xamoterol

1986

Other Studies

16 other study(ies) available for pindolol and xamoterol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Haemodynamics in postural hypotension--effects of the beta-adrenoceptor partial agonist xamoterol, and pindolol.
    European heart journal, 1990, Volume: 11 Suppl A

    Topics: Adrenergic beta-Agonists; Blood Pressure; Hemodynamics; Humans; Hypotension, Orthostatic; Pindolol; Propanolamines; Stroke Volume; Vascular Resistance; Xamoterol

1990
Effects of xamoterol on inotropic and lusitropic properties of the human myocardium and on adenylate cyclase activity.
    American heart journal, 1990, Volume: 120, Issue:6 Pt 1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Dose-Response Relationship, Drug; Heart Atria; Heart Failure; Humans; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Xamoterol

1990
Comparison of the effects of xamoterol and isoprenaline on rat cardiac beta-adrenoceptors: studies of function and regulation.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Animals; Down-Regulation; Female; Heart; Heart Rate; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Male; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta; Xamoterol

1990
The cardiovascular pharmacology of xamoterol, cicloprolol, prenalterol and pindolol in the anaesthetised dog.
    British journal of clinical pharmacology, 1989, Volume: 28 Suppl 1

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Hindlimb; Isoproterenol; Pindolol; Prenalterol; Propanolamines; Regional Blood Flow; Reserpine; Xamoterol

1989
Contrasting effects of single doses of pindolol and xamoterol on left ventricular diastolic function.
    British journal of clinical pharmacology, 1989, Volume: 28 Suppl 1

    Topics: Adrenergic beta-Agonists; Blood Pressure; Coronary Disease; Diastole; Female; Heart; Heart Rate; Humans; Male; Pindolol; Propanolamines; Xamoterol

1989
The in vitro pharmacology of xamoterol (ICI 118,587).
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; Female; Fenoterol; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Male; Muscle, Smooth; Norepinephrine; Pindolol; Propanolamines; Rats; Refractory Period, Electrophysiological; Species Specificity; Uterine Contraction; Xamoterol

1985
Treatment of idiopathic orthostatic hypotension with xamoterol.
    Lancet (London, England), 1987, Jun-20, Volume: 1, Issue:8547

    Topics: Adrenergic beta-Agonists; Humans; Hypotension, Orthostatic; Male; Middle Aged; Pindolol; Propanolamines; Xamoterol

1987
Comparative analysis of beta-1 adrenoceptor agonist and antagonist potency and selectivity of cicloprolol, xamoterol and pindolol.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Pindolol; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta; Trachea; Xamoterol

1987
Pharmacological analysis of the cardiac actions of xamoterol, a beta adrenoceptor antagonist with partial agonistic activity, in guinea pig heart: evidence for involvement of adenylate cyclase system in its cardiac stimulant actions.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Cyclic AMP; Dose-Response Relationship, Drug; Female; Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Heart Rate; Iodocyanopindolol; Isoproterenol; Male; Myocardial Contraction; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Xamoterol

1987
Independent regulation of beta 1- and beta 2-adrenoceptors.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cerebral Cortex; Clenbuterol; Desipramine; In Vitro Techniques; Iodine Radioisotopes; Male; Pindolol; Prenalterol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Xamoterol

1987
Differential effects of beta-adrenoceptor partial agonists in patients with postural hypotension.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:1

    Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hypotension, Orthostatic; Male; Middle Aged; Pindolol; Supine Position; Xamoterol

1993