Page last updated: 2024-08-16

pindolol and verapamil

pindolol has been researched along with verapamil in 77 studies

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-199037 (48.05)18.7374
1990's10 (12.99)18.2507
2000's15 (19.48)29.6817
2010's15 (19.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahman, M; Holmén, AG; Wan, H1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Akamatsu, M1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bode, ML; Gravestock, D; Hoppe, HC; Khan, T; Moleele, SS; Nkabinde, LA; Pelly, SC; Steenkamp, PA; van der Westhuyzen, CW1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hochrein, H; Lehmann, HU; Witt, E1
Henrich, H; Kababgi, MD; Schneider, KW1
Arrigo, F; Bramanti, B; Coglitore, S; Consolo, F; Giannetto, M; Melluso, C; Virga, T1
Heine, HW; Konrad, A; Lossnitzer, K; Stauch, M; Ziegler, E1
Doshchitsin, VL1
Greif, S; Harnoncourt, K; Roth, F1
Doshchitsin, VL; Fedorova, IF; Gendlin, GE; Pozin, VM; Skuratovskaia, SG1
Bernuth, G; Hofstetter, R; Lang, D1
Bakran, I; Duraković, Z; Francetić, I; Gjurasin, M; Mohacek, I; Vrhovac, B1
Endoh, M; Schümann, HJ; Wagner, J1
Clifton, GD; DeMaria, AN; Harrison, MR1
Janowsky, DS; Overstreet, DH; Rezvani, AH1
Bailey, DG; Carruthers, SG1
Arita, M; Hisatome, I; Imanishi, S; Kiyosue, T1
Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK1
Kondo, N; Pang, PK; Shibata, S; Tenner, TE1
Channer, KS; James, MA; Papouchado, M; Rees, JR1
McGourty, JC; Silas, JH; Solomon, SA1
Hof, RP1
Channer, KS; James, M1
Anavekar, SN; Doyle, AE1
Hamann, SR; Kaltenborn, KE; McAllister, RG1
Bhandari, A; Rahimtoola, SH; Rose, JS; Wu, D1
Byon, KY; Fleckenstein, A; Grün, G; Kaufmann, R1
Bender, F; Bräuer, B; Brisse, B; Müller, W1
Anderson, ST; Federman, J; Harper, RW; Laufer, E; Pitt, A; Wayne, VS1
Himori, N; Ishimori, T; Iwamura, M; Izumi, A; Makino, M; Yasuda, K1
Magometschnigg, D; Rameis, H1
Johnston, DL; Kostuk, WJ; Manyari, DE1
Arita, M; Kiyosue, T1
Szekeres, L1
Lowenthal, DT1
Hashimoto, K; Satoh, H1
Kodama, I; Kondo, N; Shibata, S1
Doyle, AE1
Sekeresh, L1
Goch, JH; Kowalski, J; Tkaczewski, W; Wichan, P1
Ceci, V; Malinconico, U; Masini, V; Milazzotto, F1
Camm, J; Martin, A; Wang, R; Ward, D; Washington, H1
Jacovella, G; Lax, A; Romei, E; Vajola, SF1
Boucher, M; Chapuy, E; Chassaing, C; Duchêne-Marullaz, P1
Arita, M; Hisatome, I1
Ikegaya, T; Kaneko, M; Kobayashi, A; Nishiyama, T; Yamazaki, N1
Giacomini, KM; Ott, RJ1
Dimitrow, PP; Dubiel, JS1
Fraudeau, C; Luck, G; Mangani, F; Vérette, E1
Alova, L; Boyanova, E; Genkova-Papasova, M; Lazarova-Bakarova, MB; Petkova, B; Stancheva, S; Staneva-Stoytcheva, D1
Asensi-Bernardi, L; Van Schepdael, A1
Cheon, SA; Chung, JF; Joo, MY; Kim, B; Kim, KH; Lee, SJ; Park, SH; Park, TJ; Seo, ES; Sood, AK; Yang, JS; Yoon, CJ1

Reviews

4 review(s) available for pindolol and verapamil

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hypertension and calcium antagonists.
    Clinical and experimental pharmacology & physiology. Supplement, 1982, Volume: 6

    Topics: Airway Resistance; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Labetalol; Pindolol; Propranolol; Verapamil

1982
Therapeutic evaluation of pindolol and verapamil in hypertrophic obstructive cardiomyopathy.
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:11

    Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Female; Humans; Male; Middle Aged; Pindolol; Verapamil

1981

Trials

11 trial(s) available for pindolol and verapamil

ArticleYear
[The treatment of angina pectoris with a fixed combination of a beta-adrenoceptor blocker and a long-acting nitrate (double-blind trial) (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1977, Nov-29, Volume: 66, Issue:48

    Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pindolol; Verapamil

1977
The effect of propranolol, prindolol, practolol and verapamil versus placebo on exercise induced tachycardia in patients with ventricular preexcitation.
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 14, Issue:2

    Topics: Adult; Exercise Test; Female; Humans; Male; Middle Aged; Physical Exertion; Pindolol; Practolol; Propranolol; Tachycardia; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome

1976
Interaction between oral verapamil and beta-blockers during submaximal exercise: relevance of ancillary properties.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:4

    Topics: Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Interactions; Exercise; Heart; Heart Rate; Humans; Male; Metoprolol; Pindolol; Propranolol; Random Allocation; Verapamil

1991
Improved control of atrial fibrillation with combined pindolol and digoxin therapy.
    European heart journal, 1989, Volume: 10, Issue:1

    Topics: Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Dyspnea; Female; Heart Rate; Humans; Middle Aged; Pindolol; Verapamil

1989
Evaluation of verapamil in the treatment of hypertension.
    Journal of clinical hypertension, 1986, Volume: 2, Issue:3 Suppl

    Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Middle Aged; Pindolol; Random Allocation; Sodium Chloride Symporter Inhibitors; Verapamil

1986
Effective termination of reentrant supraventricular tachycardia by single dose oral combination therapy with pindolol and verapamil.
    American heart journal, 1986, Volume: 112, Issue:4

    Topics: Adult; Aged; Cardiac Pacing, Artificial; Drug Combinations; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Pindolol; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Supraventricular; Verapamil

1986
[Therapeutic problems in hyperkinetic heart syndrome].
    Acta medica Austriaca, 1984, Volume: 11, Issue:1

    Topics: Adrenergic beta-Antagonists; Celiprolol; Clinical Trials as Topic; Female; Heart Rate; Humans; Male; Oxprenolol; Pindolol; Propanolamines; Tachycardia; Verapamil

1984
The clinical and hemodynamic effects of propranolol, pindolol and verapamil in the treatment of exertional angina pectoris.
    Canadian Medical Association journal, 1984, Jun-01, Volume: 130, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Physical Exertion; Pindolol; Propranolol; Random Allocation; Stroke Volume; Verapamil

1984
[Ergometric test in sympatheticotonia after administration of propranolol, pindolol, verapamil and oxazepam].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jun-09, Volume: 35, Issue:23

    Topics: Adolescent; Adrenergic Fibers; Adult; Clinical Trials as Topic; Exercise Test; Heart; Heart Failure; Humans; Male; Oxazepam; Pindolol; Propranolol; Verapamil

1980
Therapeutic evaluation of pindolol and verapamil in hypertrophic obstructive cardiomyopathy.
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:11

    Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Female; Humans; Male; Middle Aged; Pindolol; Verapamil

1981
Treatment of chronic atrial fibrillation in the elderly, assessed by ambulatory electrocardiographic monitoring.
    Journal of the American Geriatrics Society, 1980, Volume: 28, Issue:12

    Topics: Aged; Atrial Fibrillation; Digoxin; Drug Tolerance; Electrocardiography; Evaluation Studies as Topic; Female; Heart Rate; Humans; Male; Middle Aged; Pindolol; Placebos; Verapamil

1980

Other Studies

63 other study(ies) available for pindolol and verapamil

ArticleYear
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14

    Topics: Cell Line; Cell Survival; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Models, Molecular; Molecular Structure; Pyridines; Reverse Transcriptase Inhibitors; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Treatment of hypertension with a combination of pyridopyridazine derivative with a beta-receptor blocker. Studies on the hemodynamic course (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1978, Jun-09, Volume: 120, Issue:23

    Topics: Adrenergic beta-Antagonists; Aged; Cardiac Output; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pindolol; Pyridazines; Verapamil

1978
Effect of beta-sympatholytic agents on vascular responses to noradrenaline and potassium chloride.
    Acta cardiologica, 1978, Volume: 33, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Depression, Chemical; Female; Intestine, Small; Male; Mesenteric Arteries; Norepinephrine; Pindolol; Potassium Chloride; Practolol; Propranolol; Rats; Stimulation, Chemical; Vasoconstriction; Verapamil

1978
[Prinzmetal's angina. Considerations on a clinical case].
    Bollettino della Societa italiana di cardiologia, 1977, Volume: 22, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Angina Pectoris, Variant; Aspirin; Electrocardiography; Heart; Heparin; Humans; Lidoflazine; Male; Nitrates; Pindolol; Verapamil

1977
[Proceedings: Prevention of myocardial degeneration in a disease model of hereditary cardiomyopathy].
    Zeitschrift fur Kardiologie, 1975, Volume: Suppl 2

    Topics: Animals; Calcium; Cardiomegaly; Cardiomyopathies; Cricetinae; Disease Models, Animal; Heart; Myocardium; Necrosis; Pindolol; Practolol; Propranolol; Verapamil

1975
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia].
    Kardiologiia, 1975, Volume: 15, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil

1975
[Prevention of ventricular fibrillation in animal experiments].
    Kardiologiia, 1978, Volume: 18, Issue:4

    Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular Fibrillation; Verapamil

1978
[Exercise-induced tachyarrhythmic syncopes with sinus bradycardia and normal QT-interval at rest (author's transl)].
    Zeitschrift fur Kardiologie, 1977, Volume: 66, Issue:2

    Topics: Bradycardia; Child; Electrocardiography; Female; Humans; Male; Physical Exertion; Pindolol; Practolol; Syncope; Tachycardia; Verapamil

1977
Influence of temperature on the positive inotropic effects mediated by alpha-and-beta-adrenoceptors in the isolated rabbit papillary muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287, Issue:1

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Isoproterenol; Papillary Muscles; Perfusion; Phentolamine; Phenylephrine; Pindolol; Rabbits; Receptors, Adrenergic; Stimulation, Chemical; Temperature; Verapamil

1975
Hemodynamic effects of calcium channel and beta-receptor antagonists: evaluation by Doppler echocardiography.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 1

    Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Echocardiography, Doppler; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Male; Nifedipine; Pindolol; Propranolol; Verapamil

1991
Drug-induced reductions in ethanol intake in alcohol preferring and Fawn-Hooded rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Alcohol Drinking; Alcoholism; Animals; Buspirone; Drinking Behavior; Ethanol; Feeding Behavior; Fluoxetine; Male; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Rats, Wistar; Scopolamine; Self Administration; Serotonin Receptor Agonists; Species Specificity; Verapamil

1991
Isoproterenol inhibits residual fast channel via stimulation of beta-adrenoceptors in guinea-pig ventricular muscle.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:7

    Topics: Action Potentials; Animals; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Pindolol; Potassium; Receptors, Adrenergic, beta; Verapamil

1985
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
    The Journal of biological chemistry, 1986, Jun-25, Volume: 261, Issue:18

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil

1986
Electromechanical effects of bPTH-(1-34) on rabbit sinus node cells and guinea pig papillary muscles.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:5

    Topics: Action Potentials; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Parathyroid Hormone; Peptide Fragments; Pindolol; Rabbits; Ryanodine; Sinoatrial Node; Teriparatide; Verapamil

1988
Tolerability of combined treatment with verapamil and beta-blockers in angina resistant to monotherapy.
    Postgraduate medical journal, 1985, Volume: 61, Issue:713

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Drug Therapy, Combination; Drug Tolerance; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Verapamil

1985
Interaction between two calcium antagonists and two beta blockers in conscious rabbits: hemodynamic consequences of differing cardiodepressant properties.
    The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Consciousness; Drug Interactions; Hemodynamics; Humans; Isradipine; Oxadiazoles; Pindolol; Propranolol; Rabbits; Verapamil

1987
Pindolol, not verapamil, in combination with digoxin is the treatment of choice in chronic atrial fibrillation.
    Clinical science (London, England : 1979), 1989, Volume: 76, Issue:2

    Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Drug Therapy, Combination; Humans; Pindolol; Verapamil

1989
Hemodynamic and pharmacokinetic aspects of the interactions between verapamil and pindolol.
    Pharmacology, 1987, Volume: 34, Issue:6

    Topics: Animals; Dogs; Drug Interactions; Hemodynamics; Male; Pindolol; Verapamil

1987
[Differentiation between beta adrenergic and Ca 2+ antagonistic influencing components of beta receptor blockaders in the myocardium and in smooth muscles with special reference to Trasicor].
    Arztliche Forschung, 1972, Nov-10, Volume: 26, Issue:11

    Topics: Adrenergic beta-Antagonists; Allyl Compounds; Amino Alcohols; Animals; Calcium; Cats; Chick Embryo; Female; Guinea Pigs; Heart; Muscle Contraction; Muscle, Smooth; Papillary Muscles; Pindolol; Potassium; Prenylamine; Propranolol; Propylamines; Rabbits; Rats; Sotalol; Uterus; Verapamil

1972
[Plasma and tissue catecholamine concentration and antiarrhythmic influence on it].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Humans; Lidocaine; Male; Pindolol; Practolol; Rats; Verapamil

1973
Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Bradycardia; Coronary Disease; Drug Interactions; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypotension; Male; Metoprolol; Middle Aged; Pindolol; Verapamil

1982
Drug-induced inhibition of guinea pig platelet aggregation unrelated to their beta-adrenolytic actions.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Atenolol; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; In Vitro Techniques; Male; Pindolol; Platelet Aggregation; Procaine; Propranolol; Verapamil

1983
Modification of "depressed fast channel dependent slow conduction" by lidocaine and verapamil in the presence or absence of catecholamines--evidence for alteration of preferential ionic channels for slow conduction.
    Japanese circulation journal, 1983, Volume: 47, Issue:1

    Topics: Action Potentials; Animals; Catecholamines; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Ion Channels; Isoproterenol; Lidocaine; Microelectrodes; Myocardial Infarction; Papillary Muscles; Pindolol; Potassium; Verapamil

1983
A pharmacological evaluation of electrical events in the myocardium.
    Advances in myocardiology, 1982, Volume: 3

    Topics: Animals; Calcium; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Heart; Heart Rate; Ion Channels; Lidocaine; Myocardial Contraction; Myocardium; Pindolol; Potassium; Purkinje Fibers; Rabbits; Sinoatrial Node; Sodium-Potassium-Exchanging ATPase; Verapamil

1982
New drugs for hypertension.
    American family physician, 1984, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Bumetanide; Diltiazem; Dipeptides; Enalapril; Guanabenz; Guanidines; Humans; Indapamide; Labetalol; Nifedipine; Pindolol; Verapamil

1984
Effects of ftorafur and 5-fluorouracil on the canine sinoatrial node.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Aminophylline; Animals; Calcium; Dogs; Female; Fluorouracil; Heart Atria; Heart Rate; Male; Myocardial Contraction; Pindolol; Sinoatrial Node; Stimulation, Chemical; Tegafur; Verapamil

1983
Effects of amrinone on the transmembrane action potential of rabbit sinus node pacemaker cells.
    British journal of pharmacology, 1983, Volume: 80, Issue:3

    Topics: Action Potentials; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Female; Heart Conduction System; In Vitro Techniques; Male; Pindolol; Rabbits; Verapamil

1983
[Pharmacologic evaluation of electrical processes in the myocardium].
    Kardiologiia, 1982, Volume: 22, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Heart Conduction System; In Vitro Techniques; Lidocaine; Nitroglycerin; Pindolol; Verapamil

1982
[Effect of single dose administration of a new beta-blockader (pindolol) prior to onset of angina pectoris as evaluated by exercise tests on a bicycle ergometer].
    La Clinica terapeutica, 1980, Feb-15, Volume: 92, Issue:3

    Topics: Angina Pectoris; Drug Evaluation; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Pindolol; Propranolol; Verapamil

1980
Chronotropic cardiac effects of falipamil in conscious dogs: interactions with the autonomic nervous system and various ionic conductances.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovascular Agents; Dogs; Female; Heart Rate; Ion Channels; Isoindoles; Male; Phthalimides; Pindolol; Quinidine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Stimulation, Chemical; Verapamil

1994
Effects of catecholamines on the residual sodium channel dependent slow conduction in guinea pig ventricular muscles under normoxia and hypoxia.
    Cardiovascular research, 1995, Volume: 29, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Catecholamines; Dose-Response Relationship, Drug; Gallopamil; Guinea Pigs; Hypoxia; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Infarction; Myocardium; Norepinephrine; Pindolol; Potassium; Sodium Channels; Verapamil

1995
Verapamil induced reduction of the myocardial beta-adrenoceptor density in BIO 14.6 cardiomyopathic Syrian hamsters.
    Molecular and cellular biochemistry, 1993, Apr-07, Volume: 121, Issue:1

    Topics: Animals; Binding, Competitive; Calcium Channels; Cardiomyopathies; Cricetinae; Disease Models, Animal; Heart; Mesocricetus; Myocardium; Pindolol; Receptors, Adrenergic, beta; Verapamil

1993
Stereoselective interactions of organic cations with the organic cation transporter in OK cells.
    Pharmaceutical research, 1993, Volume: 10, Issue:8

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cations; Cell Line; Disopyramide; Kidney; Microvilli; Opossums; Pindolol; Quinine; Stereoisomerism; Tetraethylammonium Compounds; Verapamil

1993
Effects on left ventricular function of pindolol added to verapamil in hypertrophic cardiomyopathy.
    The American journal of cardiology, 1993, Feb-01, Volume: 71, Issue:4

    Topics: Adult; Analysis of Variance; Cardiomyopathy, Hypertrophic; Diastole; Drug Evaluation; Drug Therapy, Combination; Echocardiography; Female; Humans; Male; Pindolol; Systole; Time Factors; Ventricular Function, Left; Verapamil

1993
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
    Journal of chromatography. A, 1997, Feb-21, Volume: 762, Issue:1-2

    Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil

1997
Effects of beta-adrenoceptor blocker pindolol, calcium antagonist verapamil and their combination on retention in step-down- and shuttle-box-trained rats and on brain biogenic monoamines.
    Journal of physiology, Paris, 1997, Volume: 91, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Biogenic Monoamines; Brain; Calcium Channel Blockers; Dopamine; Drug Antagonism; Frontal Lobe; Hippocampus; Male; Memory; Norepinephrine; Pindolol; Rats; Rats, Wistar; Serotonin; Verapamil

1997
Chiral separations by non-aqueous capillary electrophoresis in DMSO-based background electrolytes.
    Talanta, 2014, Volume: 118

    Topics: Dimethyl Sulfoxide; Electrolytes; Electrophoresis, Capillary; Fenfluramine; Methanol; Pindolol; Stereoisomerism; Verapamil

2014
NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Animals; Female; Fibrosis; Heptaminol; Hyperplasia; Killer Cells, Natural; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pindolol; Skin; Tetradecanoylphorbol Acetate; Tretinoin; Verapamil

2016