Page last updated: 2024-08-16

pindolol and timolol

pindolol has been researched along with timolol in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	55 (59.78)	18.7374
1990's	14 (15.22)	18.2507
2000's	14 (15.22)	29.6817
2010's	9 (9.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bultsma, T; Donné-Op den Kelder, GM; Rademaker, B; Timmerman, H	1
Baldwin, JJ; Christy, ME; Denny, GH; Freedman, MB; Gross, DM; Habecker, CN; Lyle, PA; Ponticello, GS; Sweet, CS; Varga, SL	1
Alexander, J; Cargill, R; Michelson, SR; Schwam, H	1
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Meier, J	1
Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ	1
Wilcox, RG	1
Bühler, FR; Burkart, F; Marbet, G; Patel, U	1
Kiechel, JR; Meier, J	1
Emeriau, JP; Rumeau, M	1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S	1
Brown, B; Buckley, M; Darragh, A; Fitzgerald, D; Foley, JE; O'Kelly, D; Tormey, W; Vukovich, RA; Willard, DA	1
Drummer, O; Jarrott, B; Louis, WJ; McNeil, JJ; Rand, MJ	1
Heinze, A; Werth, HW; Wessels, F	1
Abiko, Y; Hoque, AN; Ichihara, K; Nasa, Y	1
Anderson, DR; Ferrari-Dileo, G; Feuer, WJ; Grajewski, AL	1
Cherchi, A; Sau, F; Seguro, C	1
Hansen, JE; Kayser, L; Perrild, H; Petersen, PH; Skovsted, L	1
Beusenberg, FD; Bonta, IL; Leurs, R; van Amsterdam, JG; van Schaik, A	1
Bast, A; Beusenberg, FD; Leurs, R; Timmerman, H; Van Amsterdam, JG	1
Douglas, GR; Drance, SM; Schulzer, M; Wijsman, KJ	1
Basciu, M; Cherchi, A; Pili, G; Sau, F; Seguro, C; Siddi, PP; Tamponi, R	1
Zulauf, M	1
Broadley, KJ; Williamson, KL	1
Henricks, PA; Nijkamp, FP; van Esch, B; van Oosterhout, AJ	1
Huupponen, R; Kaila, T; Karhuvaara, S	1
Diestelhorst, M; Krieglstein, GK	1
Fishbein, L; Jackson, CD	1
Strempel, I	1
Chen, J; Padillo, E; Ruiz, G; Woodward, DF	1
Srivastava, KC	1
Böhm, E; Fabel, H	1
Schnarr, KD	1
Baldwin, JJ; Gautheron, P; Grove, J; Mallorga, P; Ponticello, GS; Sugrue, MF; Varga, SL; Viader, MP	1
Flammer, J; Gloor, B; Robert, Y	1
Richard, G; Weber, J	1
Merté, HJ; Stryz, JR	1
Görlich, W	1
Hendrickson, P; Robert, Y	1
Vidt, DG	1
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C	1
Holzgreve, H; Middeke, M	1
Frishman, WH; Koch-Weser, J	1
Borer, JS; Moses, JW	1
Hedges, A; Kilfeather, S; Lima, DR; Turner, P	1
Bolte, HD	1
Lund-Johansen, P	1
Bleckmann, H; Dorow, P	1
Friedewald, WT; Frishman, WH; Furberg, CD	2
Jackson, EA; Sullman, SA	1
Chung, DC; Laschuk, MJ	1
Peele, ME; Shulkin, BL; Utiger, RD	1
McGoon, MD; Vlietstra, RE	1
Abed, J; Donaldson, R; Nashat, F; Taggart, P	1
Bromberg, BB; Gregory, DS; Sears, ML	1
Clark, B; Trope, GE	1
Remien, J	1
Andréasson, S; Jensen, KM	1
Dausch, D; Görlich, W; Honegger, H	1
Heckenhahn, K; Levermann, H; Tauchert, A; Wolf, H	1
Thind, GS	1
Edgar, DF; Rowley, S; Staunton, JE; Stewart-Jones, JH; Tosch, A; Turner, P	1
Haugen, AH; Opstad, PK; Skrede, KK; Wiik, P	1
Kahle, G; Kaulen, P; Scherer, V; Wollensak, J	1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R	1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA	1
Allegretti, P; Bertolotti, SG; Criado, S; Furlong, J; García, NA; La Falce, E; Mártire, D	1
Allegretti, P; Bertolotti, S; Criado, S; Furlong, J; García, N; La Falce, E; Mártire, D	1
Criado, S; García, NA	1
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA	1
Briuglia, ML; Lamprou, DA; Urquhart, AJ	1

Reviews

11 review(s) available for pindolol and timolol

Article	Year
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship	1988
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
Advances in the medical management of renovascular hypertension. The Urologic clinics of North America, 1984, Volume: 11, Issue:3 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propanolamines; Propranolol; Renal Artery Obstruction; Renin-Angiotensin System; Saralasin; Timolol	1984
beta-Adrenoceptor antagonists: new drugs and new indications. The New England journal of medicine, 1981, Aug-27, Volume: 305, Issue:9 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Glaucoma; Humans; Hypertension; Kinetics; Metoprolol; Migraine Disorders; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol	1981
Beta-adrenergic antagonists in the treatment of patients with heart disease. Disease-a-month : DM, 1981, Volume: 27, Issue:9 Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol	1981
Beta-adrenergic blockade for survivors of acute myocardial infarction. The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol	1984
Comparative review of beta-blocking agents. Connecticut medicine, 1984, Volume: 48, Issue:4 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Atenolol; Humans; Hypertension; Metoprolol; Migraine Disorders; Myocardial Infarction; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol	1984
The new beta-adrenergic antagonists. Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4 Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol	1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984

Trials

21 trial(s) available for pindolol and timolol

Article	Year
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension. British medical journal, 1978, Aug-05, Volume: 2, Issue:6134 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pindolol; Propranolol; Random Allocation; Timolol	1978
Effect of beta-blockers on exercise double product (systolic blood pressure x heart rate). British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Drug Evaluation; Heart Rate; Humans; Kinetics; Male; Middle Aged; Oxprenolol; Physical Exertion; Pindolol; Propanolamines; Propranolol; Time Factors; Timolol	1979
Clinical pharmacology of adrenergic-blocking drugs. Cardiology, 1979, Volume: 64 Suppl 1 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Pindolol; Placebos; Propranolol; Pulse; Timolol	1979
[Antihypertensive therapy with a new beta-blocking agent Timolol. Double blind study and comparison with Alprenolol and Pindolol (author's transl)]. Medizinische Klinik, 1977, Oct-14, Volume: 72, Issue:41 Topics: Adult; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Propanolamines; Pulse; Renin; Timolol	1977
Adrenergic and adrenolytic effects on intraocular pressure. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:1 Topics: Administration, Topical; Analysis of Variance; Drug Therapy, Combination; Epinephrine; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Placebos; Timolol	1991
[Electrocardiographic and echocardiographic changes during antihypertensive therapy]. Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:12 Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidone; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Indenes; Male; Middle Aged; Nifedipine; Oxprenolol; Pindolol; Propanolamines; Timolol	1990
Pindolol and timolol: short-term influence on angioscotomas and static brightness contrast sensitivity. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1990, Volume: 201, Issue:1 Topics: Aged; Analysis of Variance; Contrast Sensitivity; Double-Blind Method; Humans; Middle Aged; Pindolol; Scotoma; Timolol; Visual Field Tests	1990
The effect of betablockers with and without ISA on tonographic outflow facility. International ophthalmology, 1989, Volume: 13, Issue:1-2 Topics: Aqueous Humor; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Random Allocation; Timolol; Tonometry, Ocular	1989
[Immediate effect of a topical beta-blocker on breakup time]. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1986, Volume: 192, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Intraocular Pressure; Levobunolol; Male; Metipranolol; Pindolol; Tears; Timolol	1986
[Changes in lung function following administration of eyedrops containing timolol, metipranolol, pindolol and pilocarpine in healthy probands and patients with mild bronchial asthma]. Klinische Wochenschrift, 1987, Oct-01, Volume: 65, Issue:19 Topics: Airway Resistance; Asthma; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; Lung Volume Measurements; Metipranolol; Ophthalmic Solutions; Pilocarpine; Pindolol; Propanolamines; Random Allocation; Timolol	1987
Influence of pindolol and timolol treatment on the visual fields of glaucoma patients. Journal of ocular pharmacology, 1986,Fall, Volume: 2, Issue:4 Topics: Blood Pressure; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Pindolol; Prospective Studies; Timolol; Visual Fields	1986
[Effect of the beta-blockers timolol and pindolol on retinal hemodynamics--a videoangiography study]. Klinische Monatsblatter fur Augenheilkunde, 1987, Volume: 190, Issue:1 Topics: Angiography; Double-Blind Method; Female; Hemodynamics; Humans; Macula Lutea; Male; Microcirculation; Middle Aged; Pindolol; Random Allocation; Retinal Vessels; Timolol; Video Recording	1987
Duration of action of beta blockers. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol	1980
[Potassium metabolism during antihypertensive treatment with beta-receptor blocker and diuretic treatment]. Deutsche medizinische Wochenschrift (1946), 1981, Mar-27, Volume: 106, Issue:13 Topics: Adrenergic beta-Antagonists; Amiloride; Clopamide; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypokalemia; Natriuresis; Pindolol; Potassium; Timolol	1981
[Indications and contraindications of beta blockaders in the treatment of glaucoma]. Deutsche medizinische Wochenschrift (1946), 1984, Feb-03, Volume: 109, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Aged; Airway Resistance; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pindolol; Respiration; Timolol	1984
Beta-adrenergic blockade for survivors of acute myocardial infarction. The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol	1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol. The British journal of ophthalmology, 1983, Volume: 67, Issue:4 Topics: Clinical Trials as Topic; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilot Projects; Pindolol; Random Allocation; Timolol	1983
[Clinical suitability of pindolol eyedrops in the treatment of chronic open-angle glaucoma]. Klinische Monatsblatter fur Augenheilkunde, 1984, Volume: 184, Issue:6 Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pindolol; Timolol	1984
[Pindolol eye drops - a new beta receptor blockader in the therapy of open-angle glaucoma. Comparative study of 4 weeks' duration]. Die Medizinische Welt, 1983, Jun-10, Volume: 34, Issue:23 Topics: Adult; Aged; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ophthalmic Solutions; Pindolol; Random Allocation; Time Factors; Timolol	1983
A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects. The British journal of ophthalmology, 1981, Volume: 65, Issue:8 Topics: Adolescent; Adult; Female; Humans; Intraocular Pressure; Male; Pindolol; Propanolamines; Pulse; Timolol; Tonometry, Ocular	1981

Other Studies

62 other study(ies) available for pindolol and timolol

Article	Year
Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states. Journal of medicinal chemistry, 1988, Volume: 31, Issue:6 Topics: Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate; Hydrogen Bonding; Iodocyanopindolol; Liver; Models, Molecular; Pindolol; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship	1988
Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted amino)-2-hydroxypropoxy]phenyl]imidazole class. 2. Journal of medicinal chemistry, 1986, Volume: 29, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Female; Guinea Pigs; Heart Rate; Hydrogen Bonding; Imidazoles; In Vitro Techniques; Receptors, Adrenergic, beta; Solubility; Structure-Activity Relationship	1986
(Acyloxy)alkyl carbamates as novel bioreversible prodrugs for amines: increased permeation through biological membranes. Journal of medicinal chemistry, 1988, Volume: 31, Issue:2 Topics: Adrenergic beta-Antagonists; Amines; Carbamates; Cell Membrane Permeability; Pharmaceutical Preparations; Prodrugs	1988
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Once-daily treatment of hypertension. British medical journal, 1976, Jul-24, Volume: 2, Issue:6029 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Hypertension; Metoprolol; Pindolol; Propranolol; Timolol	1976
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1977, Volume: 606 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol	1977
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol	1978
Renin-suppressive potency of various beta-adrenergic blocking agents at supine rest and during upright exercise. Clinical science and molecular medicine. Supplement, 1975, Volume: 2 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Male; Oxprenolol; Physical Exertion; Pindolol; Posture; Practolol; Propranolol; Renin; Timolol	1975
[Beta-blockers and arterial hypertension in the aged patient]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Aged; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Pindolol; Timolol	1978
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol	1979
Cardioprotective effect of pindolol in ischemic-reperfused isolated rat hearts. European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2 Topics: Adenine Nucleotides; Animals; Fatty Acids, Nonesterified; Heart; Lactates; Lactic Acid; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Pindolol; Rats; Rats, Inbred Strains; Timolol	1992
Beta-adrenergic responsiveness of choroidal vasculature. Ophthalmology, 1991, Volume: 98, Issue:6 Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Animals; Autoradiography; Choroid; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Pigment Epithelium of Eye; Pindolol; Rabbits; Receptors, Adrenergic, beta; Retinal Vessels; Timolol	1991
[Effects of antihypertensive therapy with selective and non-selective beta blocking agents on dimensions and function of the left ventricle]. Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:1 Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nadolol; Pindolol; Timolol; Ventricular Function	1991
Acute beta-blockade changes the extracellular distribution of thyroid hormones. Journal of endocrinological investigation, 1990, Volume: 13, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; alpha-Macroglobulins; Carrier Proteins; Female; Humans; Male; Membrane Proteins; Middle Aged; Oxprenolol; Pindolol; Serum Albumin; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Thyroxine; Timolol; Tissue Distribution; Triiodothyronine	1990
Sensitization enhances the adenylyl cyclase responsiveness in alveolar macrophages. Changes induced at post-receptor level. Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3 Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; Iodocyanopindolol; Isoproterenol; Macrophage Activation; Macrophages; Male; Ovalbumin; Pindolol; Pulmonary Alveoli; Signal Transduction; Timolol	1991
Identification of beta 2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol. Inflammation, 1990, Volume: 14, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Guinea Pigs; Iodine Radioisotopes; Iodocyanopindolol; Macrophages; Male; Pindolol; Propanolamines; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol	1990
Do both adrenaline and noradrenaline stimulate cardiac alpha-adrenoceptors to induce positive inotropy of rat atria? British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Haloperidol; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Timolol	1989
Guinea pig alveolar macrophages possess beta-adrenergic receptors. Agents and actions, 1989, Volume: 26, Issue:1-2 Topics: Adrenergic beta-Antagonists; Animals; Guinea Pigs; Macrophages; Pindolol; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol	1989
Beta-adrenoceptor antagonist activities and binding affinities of timolol enantiomers in rat atria. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:9 Topics: Adrenergic beta-Antagonists; Animals; Heart; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Myocardium; Pindolol; Rats; Rats, Inbred Strains; Stereoisomerism; Timolol	1989
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation. Experimental eye research, 1986, Volume: 43, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Isoproterenol; Male; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol	1986
Influence of some beta blockers (pindolol, atenolol, timolol and metoprolol) on aggregation and arachidonic acid metabolism in human platelets. Prostaglandins, leukotrienes, and medicine, 1987, Volume: 29, Issue:1 Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Arachidonic Acid; Arachidonic Acids; Atenolol; Blood Platelets; Collagen; Epinephrine; Humans; Metoprolol; Phospholipids; Pindolol; Platelet Aggregation; Thromboxane B2; Timolol	1987
[Comparative multicenter study of carteolol eyedrops with other beta blockers in 768 patients under normal conditions]. Klinische Monatsblatter fur Augenheilkunde, 1988, Volume: 192, Issue:2 Topics: Adrenergic beta-Antagonists; Carteolol; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Metipranolol; Ophthalmic Solutions; Pindolol; Propanolamines; Time Factors; Timolol	1988
L-653,328: an ocular hypotensive agent with modest beta receptor blocking activity. Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Dose-Response Relationship, Drug; Intraocular Pressure; Iodine Radioisotopes; Iodocyanopindolol; Iris; Ophthalmic Solutions; Pharmacology; Pindolol; Prodrugs; Propanolamines; Rabbits; Radioligand Assay; Receptors, Adrenergic, beta; Timolol	1988
[Results of 1-year use of local pindolol in open-angle glaucoma]. Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:1 Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pindolol; Timolol	1985
[Is the use of beta receptor blockers in variously strong concentrations in the treatment of glaucoma sensible?]. Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:2 Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Pindolol; Risk; Timolol	1985
[Evaluation of the effectiveness of beta blockers on the eye]. Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:6 Topics: Adult; Blood Pressure; Humans; Intraocular Pressure; Optic Disk; Pindolol; Timolol	1985
Comparison of four different beta-adrenoceptor blocking drugs on lymphocyte isoprenaline-stimulated cyclic AMP production. British journal of clinical pharmacology, 1981, Volume: 11, Issue:6 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Cyclic AMP; Drug Interactions; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Pindolol; Timolol	1981
[Beta receptor blockaders. Pharmacokinetics and therapeutic effects]. Der Internist, 1982, Volume: 23, Issue:11 Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Biological Availability; Guinea Pigs; Humans; Kinetics; Pindolol; Propranolol; Timolol	1982
Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol. European heart journal, 1983, Volume: 4 Suppl D Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Hemodynamics; Humans; Hypertension; Metoprolol; Pindolol; Propanolamines; Time Factors; Timolol	1983
Beta-adrenergic antagonist inhibition of hepatic 3,5,3'-triiodothyronine production. Endocrinology, 1984, Volume: 115, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Dithiothreitol; Liver; Male; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Timolol; Triiodothyronine	1984
Beta-adrenergic blockers. Choosing among them. Postgraduate medicine, 1984, Sep-01, Volume: 76, Issue:3 Topics: Adrenergic beta-Antagonists; Atenolol; Cardiovascular Diseases; Humans; Kinetics; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol	1984
Class III action of beta-blocking agents. Cardiovascular research, 1984, Volume: 18, Issue:11 Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart; Heart Ventricles; Male; Nadolol; Oxprenolol; Pindolol; Propanolamines; Propranolol; Sotalol; Timolol	1984
Beta-adrenergic receptors in ciliary processes of the rabbit. Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:2 Topics: Adenylyl Cyclases; Alprenolol; Animals; Cell Membrane; Ciliary Body; Epinephrine; Isoproterenol; Male; Phentolamine; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Timolol	1980
Beta adrenergic receptors in pigmented ciliary processes. The British journal of ophthalmology, 1982, Volume: 66, Issue:12 Topics: Albuterol; Animals; Cell Membrane; Ciliary Body; In Vitro Techniques; Male; Pigmentation; Pindolol; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sheep; Timolol	1982
Beta-adrenoceptor recognition sites in living lymphocytes: a model for receptor properties in human disease? European journal of respiratory diseases. Supplement, 1984, Volume: 135 Topics: Binding Sites; Humans; Iodocyanopindolol; Lymphocytes; Pindolol; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Timolol	1984
Newer antihypertensive agents. Comprehensive therapy, 1980, Volume: 6, Issue:3 Topics: Aged; Antihypertensive Agents; Captopril; Diuretics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Mineralocorticoid Receptor Antagonists; Pindolol; Saralasin; Timolol; United States; Vasoconstrictor Agents	1980
Adrenaline stimulated cyclic adenosine monophosphate response in leucocytes is reduced after prolonged physical activity combined with sleep and energy deprivation. European journal of applied physiology and occupational physiology, 1994, Volume: 69, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Binding Sites; Binding, Competitive; Cells, Cultured; Cyclic AMP; Epinephrine; Fasting; Granulocytes; Humans; Leukocytes; Male; Monocytes; Physical Exertion; Pindolol; Sleep Deprivation; Time Factors; Timolol	1994
[Increase in beta-adrenergic receptors in rabbits in long-term local administration of beta-blockers]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1993, Volume: 90, Issue:6 Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Autoradiography; Ciliary Body; Cornea; Long-Term Care; Male; Pindolol; Rabbits; Receptors, Adrenergic, beta-2; Timolol	1993
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions. Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2 Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol	1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol	1998
Singlet molecular oxygen generation and quenching by the antiglaucoma ophthalmic drugs, Timolol and Pindolol. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2002, Volume: 1, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Glaucoma; Humans; Kinetics; Light; Photolysis; Photosensitizing Agents; Pindolol; Singlet Oxygen; Timolol	2002
Mass spectrometric study of the photooxidation of the ophthalmic drugs timolol and pindolol. Die Pharmazie, 2003, Volume: 58, Issue:8 Topics: Adrenergic beta-Antagonists; Chromatography, High Pressure Liquid; Molecular Weight; Ophthalmic Solutions; Oxidation-Reduction; Photochemistry; Photolysis; Pindolol; Quality Control; Spectrometry, Mass, Electrospray Ionization; Timolol	2003
Vitamin B2-sensitised photooxidation of the ophthalmic drugs Timolol and Pindolol: kinetics and mechanism. Redox report : communications in free radical research, 2004, Volume: 9, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Anions; Electrons; Eye; Free Radicals; Kinetics; Light; Models, Chemical; Oxygen; Oxygen Consumption; Photosensitizing Agents; Pindolol; Reactive Oxygen Species; Riboflavin; Spectrophotometry; Time Factors; Timolol; Ultraviolet Rays	2004
1H and 13C NMR characteristics of β-blockers. Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:5 Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol	2011
Sustained and controlled release of lipophilic drugs from a self-assembling amphiphilic peptide hydrogel. International journal of pharmaceutics, 2014, Oct-20, Volume: 474, Issue:1-2 Topics: Diffusion; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Peptides; Pindolol; Quinine; Surface-Active Agents; Timolol	2014