Page last updated: 2024-08-16

pindolol and penbutolol

pindolol has been researched along with penbutolol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's6 (33.33)18.2507
2000's6 (33.33)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bard, B; Carrupt, PA; Martel, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Boucher, M; Chapuy, E; DuchĂȘne-Marullaz, P1
Desager, JP; Harvengt, C; Heller, F; Hulhoven, R1
Clucas, A; Miller, N1
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C1
Kirch, W; Mutschler, E; Spahn, H2
Hjorth, S; Sharp, T1
SĂ nchez, C1
Chopin, P; Colovray, V; Fourrier, C; Halazy, S; Pallard-Sigogneau, I; Palmier, C; Pauwels, PJ; Perez, M1
Clifford, EM; Cowen, PJ; Gartside, SE; Sharp, T1
Castro, ME; Harrison, PJ; Pazos, A; Sharp, T1
Bench, CJ; Castro, ME; Cowen, PJ; Grasby, PM; Gunn, RN; Harrison, PJ; Koepp, MJ; Meyer, JH; Pazos, A; Rabiner, EA; Sargent, PA; Sharp, T1

Reviews

2 review(s) available for pindolol and penbutolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effects of acebutolol on the serum lipid profile.
    Drugs, 1988, Volume: 36 Suppl 2

    Topics: Acebutolol; Cholesterol; Humans; Lipoproteins; Penbutolol; Pindolol; Propranolol; Triglycerides

1988

Trials

2 trial(s) available for pindolol and penbutolol

ArticleYear
Duration of action of beta blockers.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol

1980
beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents; Autoradiography; Autoreceptors; Brain Chemistry; Female; Humans; In Vitro Techniques; Male; Middle Aged; Penbutolol; Pindolol; Piperazines; Propanolamines; Pyridines; Receptors, Neurotransmitter; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Thiophenes; Tomography, Emission-Computed

2000

Other Studies

14 other study(ies) available for pindolol and penbutolol

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Membrane stabilizing activity and beta-adrenoceptor antagonist-induced bradycardia in conscious dogs.
    European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Bradycardia; Consciousness; Dogs; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Block; Heart Rate; Heart Ventricles; Male; Membranes; Metoprolol; Penbutolol; Pindolol; Propranolol; Refractory Period, Electrophysiological; Stereoisomerism; Ventricular Function

1992
Beta-blocking agents and plasma lipids: an update.
    Advances in experimental medicine and biology, 1987, Volume: 210

    Topics: 1-Propanol; Adrenergic beta-Antagonists; Atenolol; Cholesterol, LDL; Coronary Disease; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, HDL2; Lipoproteins, LDL; Oxprenolol; Penbutolol; Pindolol; Sotalol

1987
The interaction between H2-receptor antagonists and beta-adrenoceptor blockers.
    British journal of clinical pharmacology, 1984, Volume: 17 Suppl 1

    Topics: Adrenergic beta-Antagonists; Atenolol; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Kinetics; Metoprolol; Penbutolol; Pindolol; Propranolol; Ranitidine

1984
The interaction of cimetidine with metoprolol, atenolol, propranolol, pindolol and penbutolol.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:4

    Topics: Atenolol; Biological Availability; Cimetidine; Drug Interactions; Guanidines; Humans; Metoprolol; Penbutolol; Pindolol; Propanolamines; Propranolol

1983
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Citalopram; Dialysis; Hippocampus; Male; Metoprolol; Penbutolol; Perfusion; Pindolol; Propanolamines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism

1993
Interaction studies of 5-HT1A receptor antagonists and selective 5-HT reuptake inhibitors in isolated aggressive mice.
    European journal of pharmacology, 1997, Sep-10, Volume: 334, Issue:2-3

    Topics: Adrenergic beta-Antagonists; Aggression; Animals; Drug Synergism; Male; Mice; Penbutolol; Pindolol; Piperazines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

1997
Design and synthesis of new potent, silent 5-HT1A antagonists by covalent coupling of aminopropanol derivatives with selective serotonin reuptake inhibitors.
    Bioorganic & medicinal chemistry letters, 1998, Dec-01, Volume: 8, Issue:23

    Topics: Animals; Drug Design; Mice; Penbutolol; Pindolol; Propranolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Stereoisomerism

1998
Effects of (-)-tertatolol, (-)-penbutolol and (+/-)-pindolol in combination with paroxetine on presynaptic 5-HT function: an in vivo microdialysis and electrophysiological study.
    British journal of pharmacology, 1999, Volume: 127, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents; Drug Synergism; Electrophysiology; In Vitro Techniques; Male; Membrane Potentials; Microdialysis; Paroxetine; Patch-Clamp Techniques; Penbutolol; Pindolol; Propanolamines; Prosencephalon; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes

1999
Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain.
    Journal of neurochemistry, 2000, Volume: 75, Issue:2

    Topics: Aged; Animals; Anti-Arrhythmia Agents; Autoradiography; Brain; Dentate Gyrus; Female; Hippocampus; Humans; Male; Penbutolol; Pindolol; Piperazines; Propanolamines; Pyridines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Synapses; Thiophenes; Tritium

2000