Page last updated: 2024-08-16

pindolol and morphine

pindolol has been researched along with morphine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's2 (11.76)18.2507
2000's7 (41.18)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davanzo, EA; McMillen, BA; Scott, SM1
O'Rourke, MF; Owensby, DA1
Hasegawa, T; Maeda, Y; Nabeshima, T; Yamada, K1
Kaneto, H; Takahashi, M; Tokuyama, S1
Ammer, H; Schulz, R1
Chambers, P; Johnson, CB; Kongara, K1

Reviews

1 review(s) available for pindolol and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for pindolol and morphine

ArticleYear
Failure of intravenous pindolol to reduce the hemodynamic determinants of myocardial oxygen demand or enzymatically determined infarct size in acute myocardial infarction.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:6

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Creatine Kinase; Female; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Myocardial Infarction; Oxygen Consumption; Pindolol; Random Allocation; Time Factors

1985
Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs.
    Veterinary anaesthesia and analgesia, 2009, Volume: 36, Issue:1

    Topics: Analgesics; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Dogs; Glomerular Filtration Rate; Isoxazoles; Morphine; Pindolol; Tramadol

2009

Other Studies

14 other study(ies) available for pindolol and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Reversal of neuroleptic-induced catalepsy by novel aryl-piperazine anxiolytic drugs.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:12

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Catalepsy; Drug Interactions; Haloperidol; Male; Methysergide; Morphine; Pindolol; Piperazines; Rats

1988
Neuronal mechanism of the inhibitory effect of calcitonin on N-methyl-D-aspartate-induced aversive behavior.
    European journal of pharmacology, 1995, Mar-06, Volume: 275, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Calcitonin; Cystamine; GABA Antagonists; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Phentolamine; Pindolol; Piperazines; Propranolol; Receptors, Neurotransmitter; Ritanserin; Serotonin Antagonists; Tropanes

1995
Involvement of serotonergic receptor subtypes in the production of antinociception by psychological stress in mice.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:3

    Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Morphine; Pain; Pindolol; Receptors, Serotonin; Serotonin Antagonists; Stress, Psychological

1993
Opioid tolerance/dependence in neuroblastoma x glioma (NG108-15) hybrid cells is associated with a reduction in spontaneous stimulatory receptor activity.
    FEBS letters, 2000, Nov-24, Volume: 485, Issue:2-3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; COS Cells; Drug Tolerance; Enzyme Inhibitors; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Iodine Radioisotopes; Morphine; Narcotics; Neuroblastoma; Pindolol; Propanolamines; Receptors, Adrenergic, beta-2; Signal Transduction; Transfection

2000