Page last updated: 2024-08-16

pindolol and carvedilol

pindolol has been researched along with carvedilol in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's4 (17.39)18.2507
2000's10 (43.48)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Bednarski, M; Dybała, M; Filipek, B; Groszek, G1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L2
Adam, W; Anderson, A; Cripps, J; Morgan, TO1
Cronin, CJ; Graham, BR; Prichard, BN; Tomlinson, B1
Gordin, A; Sundberg, S; Tiihonen, K1
Lefflerová, K; Widimský, J1
Doze, P; Elsinga, PH; Maas, B; Vaalburg, W; Van Waarde, A; Wegman, T1
Bednarski, M; Filipek, B; Groszek, G; Szafarz, M; Szymura-Oleksiak, J; Walczak, M1
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA1

Reviews

2 review(s) available for pindolol and carvedilol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Betablockers in the treatment of hypertension (with special emphasis on betablockers with ISA). A review.
    Cor et vasa, 1988, Volume: 30, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Celiprolol; Humans; Hypertension; Labetalol; Middle Aged; Pindolol; Propanolamines

1988

Trials

3 trial(s) available for pindolol and carvedilol

ArticleYear
The use of carvedilol in elderly hypertensive patients.
    European journal of clinical pharmacology, 1990, Volume: 38 Suppl 2

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Carbazoles; Carvedilol; Female; Half-Life; Heart Rate; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Nitrendipine; Pindolol; Propanolamines; Random Allocation; Single-Blind Method

1990
Haemodynamics of carvedilol in normal subjects compared with propranolol, pindolol, and labetalol.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Labetalol; Male; Physical Exertion; Pindolol; Propanolamines; Propranolol; Random Allocation

1987
Vasodilatory effects of carvedilol and pindolol.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Female; Heart Rate; Humans; Male; Pindolol; Propanolamines; Random Allocation; Respiration; Vascular Resistance; Vasodilation

1987

Other Studies

18 other study(ies) available for pindolol and carvedilol

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Synthesis and adrenolytic activity of 1-(1H-indol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol and its enantiomers. Part 1.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:2

    Topics: 2-Propanol; Adrenergic Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Hypotension; Indoles; Parasympatholytics; Propanolamines; Propanols; Rabbits; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Spasm; Stereoisomerism

2009
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes.
    The Clinical investigator, 1992, Volume: 70 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Culture Techniques; Cyclic AMP; Heart Failure; Heart Ventricles; Humans; Iodocyanopindolol; Lymphocytes; Myocardium; Pindolol; Propanolamines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasodilator Agents

1992
Receptor pharmacology of carvedilol in the human heart.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Metoprolol; Myocardium; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vasodilator Agents

1992
Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.
    Neurochemistry international, 2002, Volume: 40, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Brain; Bupranolol; Carbazoles; Carbon Radioisotopes; Carvedilol; Fluorine Radioisotopes; Male; Models, Animal; Organ Specificity; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Tissue Distribution; Tomography, Emission-Computed

2002
Application of liquid chromatography-tandem mass spectrometry method for the analysis of new nonselective beta-adrenergic blocker 1-(1-H-indol-4-yloxy)-3-{[2-(2-methoxy phenoxy)ethylo]amino}propan-2-ol (2F109) in rat plasma.
    Chirality, 2007, Volume: 19, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Drug Design; Drug Stability; Male; Pindolol; Propanolamines; Quality Control; Rats; Rats, Wistar; Stereoisomerism; Tandem Mass Spectrometry

2007
1H and 13C NMR characteristics of β-blockers.
    Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:5

    Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol

2011