Page last updated: 2024-08-16

pindolol and atropine

pindolol has been researched along with atropine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199023 (58.97)18.7374
1990's4 (10.26)18.2507
2000's7 (17.95)29.6817
2010's5 (12.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Boucher, M; Delaigue, R; Duchêne-Marullaz, P; Gueorguev, G; Kantelip, JP1
Bobik, A; Fagan, ET; Jennings, GL; Korner, PI1
Gullis, RJ; Rowe, CE1
Baile, CA; McLaughlin, CL; Seoane, JR1
Linden, J1
Earley, KJ; Gunasegaram, S; Tenner, TE1
Frame, LH; Liang, BT; Molinoff, PB1
Sommer, HJ; Stolze, HH1
Kecskemeti, V; Kelemen, K; Rubanyi, G1
Benaim, R; Chapelle, M; Lejwi, G1
Fenyvesi, T; Káldor, A; Sebestyén, K1
Combre, A; Delort, P; Duchène-Marullaz, P; Lapalus, P1
Advenier, C; Boissier, JR; Giudicelli, JF; Larno, S1
Korner, PI; McRitchie, RJ; Richards, JG; Shaw, J; Uther, JB; West, MJ1
Endoh, M; Hashimoto, K; Kimura, T1
Gabe, IT; Kimber, H; Mills, CJ; Sweeting, TJ; Thomas, M1
Delaigue-Fabry, R; Duchene-Marullaz, P; Eschalier, A; Kantelip, JP1
Eckelman, WC; Francis, B; Gibson, RE; Grissom, MP; Reba, RC1
Battersby, LA; Cruickshank, JM; Prichard, BN1
Cortés, R; Palacios, JM; Pazos, A1
Endoh, M1
Kashima, T; Kawahira, K; Kudo, A; Tanaka, H; Tanaka, N1
Amaha, K; Fudeta, H; Hirano, T; Obara, S; Yasuda, I1
Boucher, M; Chapuy, E; Chassaing, C; Duchêne-Marullaz, P1
Boucher, M; Chapuy, E; Chassaing, C; Lorente, P1
Lübbecke, F1
Boucher, M; Chapuy, E; Chassaing, C; Dubar, M1

Reviews

2 review(s) available for pindolol and atropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Overdosage with beta-adrenergic blocking agents.
    Adverse drug reactions and acute poisoning reviews, 1984,Summer, Volume: 3, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Atropine; Blood Glucose; Cardiovascular System; Central Nervous System; Drug Tolerance; Heart Rate; Humans; Kinetics; Oxprenolol; Pindolol; Propranolol; Respiration; Sotalol

1984

Trials

1 trial(s) available for pindolol and atropine

ArticleYear
Pindolol pharmacokinetics in relation to time course of inhibition of exercise tachycardia.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:3

    Topics: Adult; Atropine; Drug Interactions; Heart Rate; Humans; Kinetics; Physical Exertion; Pindolol; Time Factors

1979

Other Studies

36 other study(ies) available for pindolol and atropine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Comparative action of adrenergic beta-blockers on cardiac automatism and auriculoventricular conduction in the nonanesthetized dog].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmia, Sinus; Atropine; Depression, Chemical; Dogs; Heart Block; Heart Conduction System; Heart Rate; Myocardial Contraction; Pindolol; Propranolol

1978
Pharmacological studies on the stimulation of the phospholipase A2-acylation system of synaptic membranes of brain, by neurotransmitters and other agonists.
    Journal of neurochemistry, 1976, Volume: 26, Issue:6

    Topics: Acetylcholine; Acyltransferases; Animals; Atropine; Cerebral Cortex; Guinea Pigs; Histamine; Isoproterenol; Kinetics; Methacholine Compounds; Nicotine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Phospholipases; Pindolol; Serotonin; Swine; Synaptic Membranes; Theophylline; Tubocurarine

1976
Feeding following intrahypothalamic injections of calcium and magnesium ions in sheep.
    Journal of dairy science, 1975, Volume: 58, Issue:3

    Topics: Animals; Atropine; Calcium; Carbachol; Eating; Hypothalamus; Injections; Magnesium; Male; Phentolamine; Pindolol; Prostaglandins; Sheep

1975
Enhanced cAMP accumulation after termination of cholinergic action in the heart.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1987, Volume: 1, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Heart; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Myocardial Contraction; Myocardium; Parasympathomimetics; Pindolol; Receptors, Muscarinic

1987
Determination of beta adrenoceptor density on rabbit mononuclear leukocytes.
    Journal of pharmacological methods, 1988, Volume: 19, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Atropine; Cell Membrane; Cell Separation; Cimetidine; Leukocytes, Mononuclear; Male; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta

1988
Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:13

    Topics: Action Potentials; Animals; Atropine; Catecholamines; Dogs; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Reserpine

1985
Influence of secretagogues on volume and protein pattern in rabbit lacrimal fluid.
    Current eye research, 1985, Volume: 4, Issue:4

    Topics: Animals; Atropine; Carbachol; Electrophoresis; Eledoisin; Epinephrine; Eye Proteins; Phentolamine; Pindolol; Rabbits; Stimulation, Chemical; Sympatholytics; Tears; Vasoactive Intestinal Peptide

1985
Effects of nickel ions on the transmembrane action potential of guinea-pig heart preparations.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:5

    Topics: Action Potentials; Animals; Atropine; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Membrane Potentials; Nickel; Osmolar Concentration; Papillary Muscles; Pindolol; Potassium

1985
Effects of beta-blocking agents on atrio-ventricular and intraventricular conduction in man.
    Acta cardiologica, 1973, Volume: 28, Issue:3

    Topics: Adrenergic beta-Antagonists; Atropine; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Pindolol; Propranolol

1973
Heart rate after combined vagal and sympathetic blockade with atropine and different beta-receptor blocking agents.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aging; Atropine; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Male; Oxprenolol; Pindolol; Practolol; Propranolol; Sympathetic Nervous System; Time Factors

1973
[Nycthemeral variation in the cardiac frequency of dogs with chronic auriculo-ventricular dissociation. Role of extrinsic cardiac innervation].
    Journal de physiologie, 1972, Volume: 65

    Topics: Alprenolol; Animals; Atropine; Dogs; Heart Conduction System; Heart Rate; Periodicity; Pindolol; Propranolol

1972
Differential inotropic--chronotropic action of thyronamine.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Ethers; Guinea Pigs; Heart; Heart Atria; Heart Rate; Hemodynamics; In Vitro Techniques; Phenethylamines; Phenols; Pindolol; Propranolol; Reserpine; Thyronines; Vagotomy; Vagus Nerve

1973
Autonomic and non-autonomic circulatory components in essential hypertension in man.
    Circulation, 1973, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Atropine; Autonomic Nervous System; Blood Pressure; Body Surface Area; Cardiac Output; Electrocardiography; Guanethidine; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Phentolamine; Pindolol; Propranolol; Vascular Resistance

1973
Effects of perivascular nerve stimulation on the contraction and automaticity of the blood-perfused canine papillary muscle.
    British journal of pharmacology, 1972, Volume: 45, Issue:4

    Topics: Alprenolol; Animals; Atropine; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Perfusion; Pindolol; Propranolol; Reserpine; Tetrodotoxin

1972
Does beta-blockade directly reduce myocardial oxygen consumption?
    Cardiovascular research, 1981, Volume: 15, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Blood Pressure; Dogs; Heart; Heart Rate; Myocardium; Nitroprusside; Oxygen Consumption; Pindolol; Propanolamines

1981
Comparison of the effects of propranolol, pindolol, oxprenolol and acebutolol on atrioventricular conduction in unanaesthetized dogs.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Atrioventricular Node; Atropine; Blood Pressure; Dogs; Female; Heart Conduction System; Heart Rate; Male; Oxprenolol; Pentobarbital; Pindolol; Propranolol

1982
The use of tritium labeled compounds to develop gamma-emitting receptor-binding radiotracers.
    International journal of nuclear medicine and biology, 1982, Volume: 9, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Dihydroalprenolol; Dioxanes; Dogs; Guinea Pigs; Heart; Humans; Male; N-Methylscopolamine; Parasympatholytics; Pindolol; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rabbits; Radionuclide Imaging; Rats; Scopolamine Derivatives; Tritium

1982
Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes.
    Journal of receptor research, 1984, Volume: 4, Issue:1-6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Autoradiography; Benzodiazepinones; Binding, Competitive; Brain; Carbachol; Hippocampus; Indoles; Oxotremorine; Pindolol; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Serotonin; Superior Colliculi; Tetrahydronaphthalenes

1984
The time course of changes in cyclic nucleotide levels during cholinergic inhibition of positive inotropic actions of isoprenaline and theophylline in the isolated canine ventricular myocardium.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 312, Issue:2

    Topics: Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Pindolol; Stimulation, Chemical; Theophylline; Time Factors; Ventricular Function

1980
Dependence of the cardiovascular effects of pindolol on the individual sympathetic nervous activity.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:5

    Topics: Adult; Atropine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Parenteral; Male; Pindolol; Propranolol; Receptors, Adrenergic, beta; Sinoatrial Node; Sympathetic Nervous System

1982
Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node.
    Anesthesiology, 1982, Volume: 57, Issue:4

    Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Heart Rate; Injections, Intra-Arterial; Pindolol; Reserpine; Sinoatrial Node; Succinylcholine

1982
Chronotropic cardiac effects of falipamil in conscious dogs: interactions with the autonomic nervous system and various ionic conductances.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovascular Agents; Dogs; Female; Heart Rate; Ion Channels; Isoindoles; Male; Phthalimides; Pindolol; Quinidine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Stimulation, Chemical; Verapamil

1994
Chronotropic cardiac effects of NPY in conscious dogs: interactions with the autonomic nervous system and putative NPY receptors.
    Regulatory peptides, 1994, Dec-15, Volume: 54, Issue:2-3

    Topics: Animals; Atropine; Blood Pressure; Dogs; Female; Heart Rate; Male; Neuropeptide Y; Pindolol; Receptors, Neuropeptide Y

1994
Myocardial alterations in chronic experimental renal failure.
    Contributions to nephrology, 1994, Volume: 106

    Topics: Animals; Atrial Function, Left; Atropine; Carbachol; Cardiomyopathies; Dobutamine; Kidney Failure, Chronic; Male; Myocardial Contraction; Myocardium; Nephrectomy; Norepinephrine; Pindolol; Rats; Rats, Wistar; Uremia; Ventricular Function, Left

1994
Interactions of the cardiac chronotropic effects of rilmenidine with the autonomic nervous system in conscious dogs: comparison with clonidine.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Chronic Disease; Clonidine; Depression, Chemical; Dogs; Female; Heart Block; Heart Rate; Male; Muscarinic Antagonists; Oxazoles; Phenoxybenzamine; Pindolol; Rilmenidine; Yohimbine

1996