pinacolyl dimethylphosphinate has been researched along with soman in 8 studies
*Soman: An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent. [MeSH]
*Soman: An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent. [MeSH]
| Studies (pinacolyl dimethylphosphinate) | Trials (pinacolyl dimethylphosphinate) | Recent Studies (post-2010) (pinacolyl dimethylphosphinate) | Studies (soman) | Trials (soman) | Recent Studies (post-2010) (soman) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 1,391 | 4 | 257 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benschop, HP; Wesselman, HC | 1 |
| van der Wiel, HJ; Van Helden, HP; Wolthuis, OL | 2 |
| De Lange, J; Van Dongen, CJ | 1 |
| Benschop, HP; Bijleveld, EC; De Jong, LP; Van der Wiel, HJ; Van Helden, HP | 1 |
| Van Dongen, CJ; Van Helden, HP; Wolthuis, OL | 1 |
| Brank, M; Brzin, M; Grubic, Z | 1 |
| Brank, M; Grubic, Z; Sentjurc, M; Stalc, A | 1 |
8 other study(ies) available for pinacolyl dimethylphosphinate and soman
| Article | Year |
|---|---|
Pharmacokinetics of the soman simulant 1,2,2-trimethylpropyl dimethylphosphinate (PDP) in rats.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, Gas; Drug Stability; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Solubility; Soman | 1989 |
Prophylactic and therapeutic efficacy of the soman-simulator, pinacolyl dimethylphosphinate.
Topics: Animals; Antidotes; Atropine; Injections, Intravenous; Lethal Dose 50; Male; Neuromuscular Junction; Oximes; Pyridinium Compounds; Rats; Rats, Inbred Strains; Soman; Synaptic Transmission; Time Factors | 1986 |
Influence of pinacolyl dimethylphosphinate on soman storage in rats.
Topics: Animals; Chromatography, Gas; Diaphragm; In Vitro Techniques; Kinetics; Lung; Male; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Soman | 1987 |
Retention of soman in rats, guinea-pigs and marmosets: species-dependent effects of the soman simulator, pinacolyl dimethylphosphinate (PDP).
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Callitrichinae; Electrophorus; Female; Guinea Pigs; Male; Muscles; Oximes; Pyridinium Compounds; Soman; Species Specificity | 1988 |
Toxicokinetics of the four stereoisomers of the nerve agent soman in atropinized rats--influence of a soman simulator.
Topics: Animals; Atropine; Blood Pressure; Half-Life; Hematocrit; Lethal Dose 50; Male; Rats; Rats, Inbred Strains; Soman; Stereoisomerism | 1987 |
Further evidence for the effect of pinacolyl dimethylphosphinate on soman storage in muscle tissue.
Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Soman | 1986 |
The effects of pretreatment with soman simulator in the skeletal muscle: direct interactions with acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Drug Interactions; Female; Humans; Kinetics; Muscles; Phosphorylation; Rats; Rats, Wistar; Soman; Time Factors | 1993 |
The influence of soman simulator on reactivation by HI-6 of soman-inhibited acetylcholinesterase in preparations of rat and human skeletal muscle.
Topics: Acetylcholine; Animals; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Electron Spin Resonance Spectroscopy; Electrophorus; Humans; In Vitro Techniques; Models, Biological; Motor Endplate; Muscles; Oximes; Phosphorylation; Pyridinium Compounds; Rats; Soman | 1993 |