pinacidil has been researched along with tolbutamide in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (19.35) | 18.7374 |
| 1990's | 8 (25.81) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 10 (32.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higashiguchi, O; Horio, Y; Isomoto, S; Kondo, C; Kurachi, Y; Matsumoto, S; Matsuzawa, Y; Yamada, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Kanno, M; Nakaya, H; Takeda, Y; Tohse, N | 1 |
| Antoine, MH; Berkenboom, G; Fang, ZY; Fontaine, J; Herchuelz, A; Hermann, M; Lebrun, P | 1 |
| Wilson, C | 1 |
| Brayden, JE; Davies, NW; Huang, Y; Nelson, MT; Quayle, JM; Standen, NB | 1 |
| Devreux, V; Herchuelz, A; Hermann, M; Lebrun, P | 1 |
| Sanguinetti, MC; Siegl, PK; Wolleben, CD | 1 |
| Wahl, M | 1 |
| Grafe, P; Lehmann-Horn, F; Quasthoff, S; Spuler, A | 1 |
| Nakaya, H | 1 |
| Van Wagoner, DR | 1 |
| Aguilar-Bryan, L; Babenko, AP; Bryan, J; Gonzalez, G | 1 |
| Carpenter, E; Peers, C; Roberts, ML; Taylor, SC | 1 |
| Ammälä, C; Chapman, JC; Cosgrove, KE; Dunne, MJ; Flatt, PR; Giesberts, AN; Hashmi, MN; McClenaghan, NH; Shepherd, RM; White, SJ | 1 |
| Dallaporta, M; Orsini, JC; Perrin, J | 1 |
| Kang, YY; Kim, JA; Lee, YS | 1 |
| Bielfeld-Ackermann, A; Konstas, AA; Korbmacher, C | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC | 1 |
| Acevedo, JJ; Darszon, A; de la Vega-Beltrán, JL; Felix, R; Mendoza-Lujambio, I; Treviño, CL | 1 |
| Davison, AS; Hine, TJ; Holmes, E; Roberts, NB; Sodi, R | 1 |
| Henquin, JC; Nenquin, M; Szollosi, A | 1 |
| Breschi, MC; Calderone, V; Cecchetti, V; Martelli, A; Sabatini, S; Testai, L | 1 |
| Beutler, B; Bodmer, R; Chtarbanova, S; Eleftherianos, I; Hoffmann, JA; Imler, JL; Ocorr, K; Squiban, B; Won, S | 1 |
| Anderson, TD; Bloomquist, JR; O'Neal, ST; Swale, DR | 1 |
1 review(s) available for pinacidil and tolbutamide
| Article | Year |
|---|---|
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium; Potassium Channels; Pyrroles; Tolbutamide | 1993 |
30 other study(ies) available for pinacidil and tolbutamide
| Article | Year |
|---|---|
A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Base Sequence; Cell Line; Cloning, Molecular; DNA, Complementary; Humans; Mice; Molecular Sequence Data; Muscle, Smooth; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Sulfonylurea Receptors | 1996 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Glyburide; Guanidines; Guinea Pigs; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Perfusion; Pinacidil; Potassium Channels; Sulfonylurea Compounds; Tolbutamide | 1991 |
Hypoglycemic sulfonylureas antagonize the effects of cromakalim and pinacidil on 86Rb fluxes and contractile activity in the rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parasympatholytics; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sulfonylurea Compounds; Tetraethylammonium Compounds; Tolbutamide; Vasodilator Agents | 1990 |
Inhibition by sulphonylureas of vasorelaxation induced by K+ channel activators in vitro.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Drug Interactions; Glipizide; Glyburide; Guanidines; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Pyrroles; Rabbits; Sulfonylurea Compounds; Tolbutamide; Vasodilator Agents | 1989 |
Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Benzopyrans; Cerebral Arteries; Cromakalim; Diazoxide; Glyburide; Guanidines; Mesenteric Arteries; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Rats; Tolbutamide; Vasoactive Intestinal Peptide; Vasodilator Agents | 1989 |
Similarities between the effects of pinacidil and diazoxide on ionic and secretory events in rat pancreatic islets.
Topics: Animals; Calcimycin; Calcium; Cell Membrane Permeability; Diazoxide; Glucose; Guanidines; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Pinacidil; Potassium; Rats; Rubidium; Secretory Rate; Tolbutamide | 1989 |
Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Glyburide; Guanidines; Heart; Heart Rate; In Vitro Techniques; Male; Perfusion; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Tolbutamide; Vascular Resistance | 1989 |
The effects of pinacidil and tolbutamide in feline pial arteries in situ.
Topics: Animals; Arterioles; Cats; Guanidines; Pia Mater; Pinacidil; Potassium Channels; Tolbutamide; Vasodilation; Vasodilator Agents | 1989 |
Cromakalim, pinacidil and RP 49356 activate a tolbutamide-sensitive K+ conductance in human skeletal muscle fibres.
Topics: Benzopyrans; Cromakalim; Guanidines; Humans; In Vitro Techniques; Membrane Potentials; Muscles; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Tolbutamide; Vasodilator Agents | 1989 |
Mechanosensitive gating of atrial ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Electrophysiology; Glyburide; Guanidines; Heart Atria; Ion Channel Gating; Myocardium; Pinacidil; Potassium Channels; Pressure; Rats; Rats, Wistar; Tolbutamide | 1993 |
Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Animals; ATP-Binding Cassette Transporters; Child; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; Cromakalim; Diazoxide; DNA, Complementary; Gene Library; Glyburide; Heart Ventricles; Humans; Magnesium; Middle Aged; Myocardium; Patch-Clamp Techniques; Pinacidil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Sarcolemma; Sulfonylurea Receptors; Tolbutamide; Transfection | 1998 |
Potentiation of quantal catecholamine secretion by glibenclamide: evidence for a novel role of sulphonylurea receptors in regulating the Ca(2+) sensitivity of exocytosis.
Topics: Animals; ATP-Binding Cassette Transporters; Caffeine; Calcium; Catecholamines; Cromakalim; Egtazic Acid; Electrochemistry; Exocytosis; Glyburide; Kinetics; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pinacidil; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Quantum Theory; Rats; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide | 1999 |
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cell Fusion; Cell Line; Diazoxide; Glucose; Imidazoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Membrane Potentials; Pancreatic Neoplasms; Phentolamine; Pinacidil; Potassium Channels; Tolbutamide; Tumor Cells, Cultured | 1999 |
Involvement of adenosine triphosphate-sensitive K+ channels in glucose-sensing in the rat solitary tract nucleus.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Diazoxide; Glyburide; Homeostasis; Hypoglycemia; Hypoglycemic Agents; Male; Nerve Tissue Proteins; Neurons; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Solitary Nucleus; Tolbutamide | 2000 |
Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.
Topics: Adenosine Triphosphate; Amiloride; Apoptosis; Bepridil; Bumetanide; Calcium; Carrier Proteins; DNA Fragmentation; Dose-Response Relationship, Drug; Furosemide; Glyburide; Hepatoblastoma; Humans; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Time Factors; Tolbutamide; Tumor Cells, Cultured | 2001 |
Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression.
Topics: Animals; ATP-Binding Cassette Transporters; Cystic Fibrosis Transmembrane Conductance Regulator; Diazoxide; Diuretics; Epithelial Sodium Channels; Glyburide; Hypoglycemic Agents; Oocytes; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sodium Channel Blockers; Sodium Channels; Sodium Chloride Symporter Inhibitors; Sulfonylurea Receptors; Time Factors; Tolbutamide; Vasodilator Agents; Xenopus laevis | 2001 |
Pharmacological evidence for the activation of K(+) channels by diclofenac.
Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Hindlimb; Morphine; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2002 |
KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Barium; Diazoxide; Dose-Response Relationship, Drug; Glyburide; KATP Channels; Male; Membrane Potentials; Mice; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Pinacidil; Potassium Channels, Inwardly Rectifying; Receptors, Drug; RNA, Messenger; Sperm Capacitation; Spermatogenesis; Spermatozoa; Sulfonylurea Receptors; Time Factors; Tolbutamide | 2006 |
The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase.
Topics: Blood Glucose; Diazoxide; Enzyme Activation; Humans; Hypokalemia; Membrane Transport Modulators; Pinacidil; Potassium; Sodium-Potassium-Exchanging ATPase; Temperature; Tolbutamide | 2009 |
Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels.
Topics: Animals; Benzofurans; Calcium; Cytosol; Diazoxide; Female; Imidazoles; Imidazolines; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Mice; Mice, Knockout; Phentolamine; Pinacidil; Potassium Channels; Tolbutamide | 2010 |
Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.
Topics: Animals; Benzothiadiazines; Cromakalim; Decanoic Acids; Ether-A-Go-Go Potassium Channels; Glyburide; Guinea Pigs; Heart; Humans; Hydroxy Acids; Intracellular Membranes; KATP Channels; Long QT Syndrome; Male; Membrane Transport Modulators; Mitochondrial Membranes; Picolines; Pinacidil; Potassium Channel Blockers; Pyrans; Sarcolemma; Tolbutamide | 2010 |
ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections.
Topics: Animals; Drosophila; Heart; HeLa Cells; Humans; Immunity, Innate; Immunoblotting; KATP Channels; Mice; Mice, Inbred C57BL; Nodaviridae; Pinacidil; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tolbutamide; Viral Load; Viremia | 2011 |
ATP-sensitive inwardly rectifying potassium channel modulators alter cardiac function in honey bees.
Topics: Adenosine Triphosphate; Animals; Barium; Bees; Heart; Heart Rate; KATP Channels; Magnesium; Pinacidil; Tolbutamide | 2017 |