Page last updated: 2024-08-16

pinacidil and niacinamide

pinacidil has been researched along with niacinamide in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (15.79)	18.7374
1990's	44 (77.19)	18.2507
2000's	2 (3.51)	29.6817
2010's	2 (3.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Fang, D; Wu, Y	1
Braida, C; Holzmann, S; Kukovetz, WR; Pöch, G	1
Cook, D; Stockbridge, N; Vollrath, B; Weir, B; Zhang, H	1
Kau, ST; Li, JH; Zografos, P	1
Kamijo, T; Kido, H; Miwa, A; Nakamura, F; Sugimoto, T; Tomaru, T; Uchida, Y	1
McPherson, GA; Stork, AP	1
Andersson, KE	1
Hamilton, TC; Longman, SD	1
Chiba, S; Horiuchi, A; Iwatsuki, K; Yonekura, H	1
Berdeaux, A; Giudicelli, JF; Richer, C	1
Higuera, TR; Kadowitz, PJ; Kvamme, P; Minkes, RK; Nossaman, BD	1
Satoh, K; Taira, N; Yamada, H	1
Akahane, K; Chiba, S; Furukawa, Y; Ogiwara, Y	1
Ksoll, E; Mackert, JR; Parsons, AA; Schilling, L; Wahl, M	1
Goto, S; Kitagaki, K; Koda, A; Nagai, H; Suda, H	1
Kurachi, Y; Machulda, MM; Shen, WK; Tung, RT	1
Stockbridge, N; Weir, B; Zhang, H	1
Hirabayashi, M; Ikegaki, I; Matsusawa, M; Nakanishi, T; Nishimura, M; Takahashi, H; Yoshimura, M	1
Colatsky, T; Follmer, C; Parsons, R; Spinelli, W	1
Taira, N; Teshigawara, T; Yanagisawa, T	1
Satoh, E; Taira, N; Yanagisawa, T	1
Dunne, MJ	1
Clapham, JC; Hamilton, TC; Longman, SD; Wilson, C	1
Hamilton, TC; Weston, AH	1
Hashimoto, H; Taira, N; Yanagisawa, T	2
Eltze, M	1
Garrino, MG; Henquin, JC; Plant, TD	2
Coldwell, MC; Cooper, SM; Hamilton, TC; Howlett, DR; Wilson, C	1
Imai, S; Matsui, K; Ogawa, Y	1
Satoh, H	2
Attolini, L; Bruguerolle, B; Gantenbein, M	1
Berdeaux, A; Dubois-Randé, JL; Ghaleh, B; Giudicelli, JF; Hittinger, L	1
Atwal, KS	1
Cook, D; Zhang, H	1
Jahangir, A; Kurachi, Y; Terzic, A	1
Christensen, H; Drottning, P; Storstein, L	1
Fabiani, ME; Story, DF	1
Cavero, I; Premmereur, J	1
Kamouchi, M; Kitamura, K	1
Fan, Z; Furukawa, T; Hiraoka, M; Nakayama, K; Sawanobori, T	1
Satoh, K	1
Nakaya, H	1
Allard, B; Lazdunski, M	1
Bertaina, V; Heurteaux, C; Lazdunski, M; Widmann, C	1
Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L	1
Horio, Y; Isomoto, S; Kondo, C; Kurachi, Y; Matsumoto, S; Shindo, T; Yamada, M	1
Chujo, M; Critz, SD; Downey, JM; Liu, GS	1
Grover, GJ	1
Hori, M; Horio, Y; Isomoto, S; Kitakaze, M; Kondo, C; Kurachi, Y; Okuyama, Y; Satoh, E; Shindo, T; Yamada, M	1
Horio, Y; Isomoto, S; Kurachi, Y; Shindo, T; Yamada, M	1
Heywood, GJ; Thomas, PS	1
Di Girolamo, N; Heywood, GJ; Thomas, PS; Wei, XM	1

Reviews

9 review(s) available for pinacidil and niacinamide

Article	Year
[Advance in pharmacology of potassium channels in cardiovascular system and their clinical use]. Zhonghua yi xue za zhi, 1992, Volume: 72, Issue:3 Topics: Benzopyrans; Cromakalim; Guanidines; Humans; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1992
Clinical pharmacology of potassium channel openers. Pharmacology & toxicology, 1992, Volume: 70, Issue:4 Topics: Antihypertensive Agents; Benzopyrans; Cardiovascular System; Cromakalim; Guanidines; Humans; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Respiratory System	1992
Potassium channel activator drugs: mechanism of action, pharmacological properties, and therapeutic potential. Medicinal research reviews, 1992, Volume: 12, Issue:2 Topics: Animals; Antihypertensive Agents; Benzopyrans; Cardiovascular System; Central Nervous System; Clinical Trials as Topic; Cromakalim; Disease Models, Animal; Guanidines; Humans; Muscle, Smooth, Vascular; Muscles; Neurons; Niacinamide; Nicorandil; Pancreas; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1992
Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle. General pharmacology, 1989, Volume: 20, Issue:1 Topics: Animals; Guanidines; Humans; Niacinamide; Nicorandil; Pinacidil; Potassium Channels	1989
Pharmacology and structure-activity relationships for KATP modulators: tissue-selective KATP openers. Journal of cardiovascular pharmacology, 1994, Volume: 24 Suppl 4 Topics: Action Potentials; Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Cardiovascular Diseases; Cromakalim; Diazoxide; Guanidines; Guinea Pigs; Minoxidil; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Radioligand Assay; Rats; Structure-Activity Relationship; Vasodilator Agents	1994
Cerebral vascular smooth muscle potassium channels and their possible role in the management of vasospasm. Pharmacology & toxicology, 1994, Volume: 75, Issue:6 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Electrophysiology; Guanidines; Ischemic Attack, Transient; Muscle, Smooth, Vascular; Neuropeptides; Niacinamide; Nicorandil; Nitric Oxide; Pinacidil; Potassium Channels; Pyrroles; Vasoconstriction; Vasodilator Agents	1994
[Ca-antagonist, K-channel-opener in the treatment of patients with congestive heart failure]. Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:5 Topics: Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Guanidines; Heart Failure; Hemodynamics; Humans; In Vitro Techniques; Ion Channel Gating; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1993
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias]. Kokyu to junkan. Respiration & circulation, 1993, Volume: 41, Issue:6 Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Glyburide; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium; Potassium Channels; Pyrroles; Tolbutamide	1993
Pharmacology of ATP-sensitive potassium channel (KATP) openers in models of myocardial ischemia and reperfusion. Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:4 Topics: Animals; ATP-Binding Cassette Transporters; Benzopyrans; Cromakalim; Guanidines; Humans; Ischemic Preconditioning, Myocardial; KATP Channels; Mitochondria, Heart; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrans; Pyrroles; Rats	1997

Other Studies

48 other study(ies) available for pinacidil and niacinamide

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil. European journal of pharmacology, 1992, Apr-29, Volume: 215, Issue:1 Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide; Guanidines; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Niacinamide; Nicorandil; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Sensitivity and Specificity; Vasodilator Agents	1992
Vasodilatation of canine cerebral arteries by nicorandil, pinacidil and lemakalim. General pharmacology, 1992, Volume: 23, Issue:2 Topics: Animals; Basilar Artery; Benzopyrans; Cerebral Arteries; Cromakalim; Dogs; Female; Glyburide; Guanidines; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilation; Vasodilator Agents	1992
Comparison of the in vitro effects of K+ channel modulators on detrusor and portal vein strips from guinea pigs. Pharmacology, 1992, Volume: 45, Issue:4 Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Minoxidil; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Vasoconstriction; Vasodilator Agents	1992
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:4 Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models, Animal; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Ion Channel Gating; Male; Methylene Blue; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1992
The resistance of some rat cerebral arteries to the vasorelaxant effect of cromakalim and other K+ channel openers. British journal of pharmacology, 1992, Volume: 105, Issue:1 Topics: Acetylcholine; Animals; Antihypertensive Agents; Benzopyrans; Cerebellum; Cerebral Arteries; Cromakalim; Guanidines; Guinea Pigs; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasodilator Agents	1992
Effects of N-(2-hydroxyethyl)nicotinamide nitrate (nicorandil; SG-75) and its derivatives on pancreatic exocrine secretion in the dog. Pancreas, 1990, Volume: 5, Issue:1 Topics: Amylases; Animals; Bicarbonates; Dogs; Female; Guanidines; Male; Niacinamide; Nicorandil; Nitroglycerin; Pancreatic Juice; Pinacidil; Secretory Rate; Structure-Activity Relationship; Tetraethylammonium Compounds	1990
[Potassium channel activators. Perspectives in the treatment of arterial hypertension]. Presse medicale (Paris, France : 1983), 1991, Jan-19, Volume: 20, Issue:2 Topics: Antihypertensive Agents; Benzopyrans; Cromakalim; Guanidines; Humans; Hypertension; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles	1991
Analysis of pulmonary and systemic vascular responses to cromakalim, an activator of K+ATP channels. The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2 Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Blood Circulation; Cats; Cromakalim; Endothelins; Glyburide; Guanidines; Heart Rate; Hindlimb; Myocardial Contraction; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pulmonary Circulation; Pyrroles; Vascular Resistance; Vasodilator Agents; Ventricular Function, Right	1991
Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Guanidines; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Pinacidil; Potassium; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Vasodilator Agents	1991
K+ channel blocking and anti-muscarinic effects of a novel piperazine derivative, INO 2628, on the isolated dog atrium. European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2 Topics: Adenosine; Animals; Atrial Function; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart Atria; Myocardial Contraction; Niacinamide; Nicardipine; Nicorandil; Pinacidil; Piperazines; Potassium Channels; Time Factors	1991
Analysis of cromakalim-, pinacidil-, and nicorandil-induced relaxation of the 5-hydroxytryptamine precontracted rat isolated basilar artery. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:4 Topics: Animals; Basilar Artery; Benzopyrans; Cromakalim; Drug Interactions; Glyburide; Guanidines; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Vasoconstriction; Vasodilation; Vasodilator Agents	1991
Effect of three novel K+ channel openers, cromakalim, pinacidil and nicorandil on allergic reaction and experimental asthma. Japanese journal of pharmacology, 1991, Volume: 56, Issue:1 Topics: Airway Resistance; Animals; Asthma; Benzopyrans; Bronchodilator Agents; Cromakalim; Guanidines; Guinea Pigs; In Vitro Techniques; Mice; Mice, Inbred Strains; Niacinamide; Nicorandil; Passive Cutaneous Anaphylaxis; Pinacidil; Potassium Channels; Pyrroles; Rats; Trachea; Vasculitis	1991
Essential role of nucleotide diphosphates in nicorandil-mediated activation of cardiac ATP-sensitive K+ channel. A comparison with pinacidil and lemakalim. Circulation research, 1991, Volume: 69, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Guanidines; Myocardium; Niacinamide; Nicorandil; Phosphorylation; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1991
Effects of pinacidil, cromakalim, and nicorandil on potassium currents of rat basilar artery smooth muscle. Advances in experimental medicine and biology, 1991, Volume: 304 Topics: Animals; Antihypertensive Agents; Basilar Artery; Benzopyrans; Calcium; Cerebrovascular Circulation; Cromakalim; Electrophysiology; Guanidines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains	1991
Intracerebroventricular injections of endothelin increase arterial pressure in conscious rats. Japanese circulation journal, 1990, Volume: 54, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Endothelins; Guanidines; Injections, Intraventricular; Male; Niacinamide; Nicardipine; Nicorandil; Pinacidil; Quinazolines; Rats; Rats, Inbred Strains; Vasodilator Agents	1990
Effects of cromakalim, pinacidil and nicorandil on cardiac refractoriness and arterial pressure in open-chest dogs. European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3 Topics: Animals; Atrioventricular Node; Benzopyrans; Blood Pressure; Cromakalim; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Guanidines; Heart Conduction System; Heart Rate; Male; Neural Conduction; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Refractory Period, Electrophysiological	1990
Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Coronary Vessels; Cromakalim; Cytoplasm; Dogs; Female; Fluorescence; Glyburide; Guanidines; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Chloride; Pyrroles; Quaternary Ammonium Compounds	1990
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle. Japanese journal of pharmacology, 1990, Volume: 54, Issue:2 Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dogs; Female; Glyburide; Guanidines; Heart Atria; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1990
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells. British journal of pharmacology, 1990, Volume: 99, Issue:3 Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Diazoxide; Glucose; Guanidines; Humans; Insulin; Insulinoma; Islets of Langerhans; Membrane Potentials; Niacinamide; Nicorandil; Pancreatic Neoplasms; Picolines; Pinacidil; Potassium Channels; Pyrans; Rubidium Radioisotopes; Tumor Cells, Cultured	1990
Cromakalim, a potassium channel activator: a comparison of its cardiovascular haemodynamic profile and tissue specificity with those of pinacidil and nicorandil. Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:5 Topics: Animals; Antihypertensive Agents; Benzopyrans; Cats; Coronary Circulation; Cromakalim; Female; Guanidines; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Organ Specificity; Papillary Muscles; Pinacidil; Portal Vein; Potassium Channels; Pyrroles; Rabbits	1988
Interaction of potassium channel openers and blockers in canine atrial muscle. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: Animals; Barium; Barium Compounds; Chlorides; Dogs; Female; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Quaternary Ammonium Compounds; Tetraethylammonium Compounds	1989
Glibenclamide is a competitive antagonist of cromakalim, pinacidil and RP 49356 in guinea-pig pulmonary artery. European journal of pharmacology, 1989, Jun-20, Volume: 165, Issue:2-3 Topics: Animals; Benzopyrans; Cromakalim; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Potassium Chloride; Pulmonary Artery; Purinones; Pyrans; Pyrroles; Tetraethylammonium Compounds	1989
Comparison of the effects of putative activators of K+ channels on pancreatic B-cell function. Pflugers Archiv : European journal of physiology, 1989, Volume: 414 Suppl 1 Topics: Animals; Benzopyrans; Cromakalim; Diazoxide; Guanidines; In Vitro Techniques; Islets of Langerhans; Mice; Minoxidil; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1989
Effects of putative activators of K+ channels in mouse pancreatic beta-cells. British journal of pharmacology, 1989, Volume: 98, Issue:3 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Diazoxide; Electrophysiology; Female; Glucose; Guanidines; Homeostasis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Minoxidil; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rubidium Radioisotopes	1989
Comparative effects of K+ channel blockade on the vasorelaxant activity of cromakalim, pinacidil and nicorandil. European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3 Topics: 4-Aminopyridine; Aminopyridines; Animals; Benzopyrans; Cardiovascular Agents; Cromakalim; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Procaine; Pyrroles; Rabbits; Rubidium Radioisotopes; Tetraethylammonium Compounds; Vasodilator Agents	1988
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle. British journal of pharmacology, 1988, Volume: 95, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents	1988
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:1 Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium; Swine; Vasodilator Agents	1986
Effects of ATP-sensitive K+ channel openers on pacemaker activity in isolated single rabbit sino-atrial node cells. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:6 Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; Guanidines; Heart Rate; In Vitro Techniques; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rabbits; Sinoatrial Node; Vasodilator Agents	1993
Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice. Life sciences, 1995, Volume: 57, Issue:10 Topics: Animals; Benzopyrans; Bupivacaine; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Guanidines; Male; Mice; Mice, Inbred Strains; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Seizures	1995
Comparisons of the effects of nicorandil, pinacidil, nicardipine and nitroglycerin on coronary vessels in the conscious dog: role of the endothelium. British journal of pharmacology, 1995, Volume: 114, Issue:2 Topics: Acetylcholine; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Guanidines; Heart Rate; Niacinamide; Nicardipine; Nicorandil; Nitroglycerin; Pinacidil; Vascular Resistance; Vasodilator Agents	1995
Intracellular acidification and ADP enhance nicorandil induction of ATP sensitive potassium channel current in cardiomyocytes. Cardiovascular research, 1994, Volume: 28, Issue:6 Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Membrane Potentials; Myocardium; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Protons; Vasodilator Agents	1994
[Potassium channel openers. A new possible therapeutic principle in several diseases]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1994, Feb-10, Volume: 114, Issue:4 Topics: Antihypertensive Agents; Benzopyrans; Bronchodilator Agents; Cromakalim; Guanidines; Humans; Minoxidil; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1994
Prejunctional effects of cromakalim, nicorandil and pinacidil on noradrenergic transmission in rat isolated mesenteric artery. Journal of autonomic pharmacology, 1994, Volume: 14, Issue:2 Topics: Animals; Benzopyrans; Calcium; Cromakalim; Desipramine; Electric Stimulation; Extracellular Space; Female; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Neuromuscular Junction; Niacinamide; Nicorandil; Norepinephrine; Pargyline; Phentolamine; Pinacidil; Pyrroles; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Vasodilator Agents	1994
ATP sensitive potassium channel openers are of potential benefit in ischaemic heart disease. Cardiovascular research, 1994, Volume: 28, Issue:1 Topics: Benzopyrans; Cromakalim; Dihydropyridines; Guanidines; Humans; Myocardial Ischemia; Myocardium; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Sodium-Potassium-Exchanging ATPase; Vasodilator Agents	1994
Regulation of ATP-sensitive K+ channels by ATP and nucleotide diphosphate in rabbit portal vein. The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Egtazic Acid; Guanidines; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Membrane Potentials; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Portal Vein; Potassium Channels; Probability; Pyrroles; Rabbits; Ribonucleotides; Time Factors; Vasodilator Agents	1994
Activation and reactivation of the ATP-sensitive K+ channel of the heart can be modified by drugs. Cardiovascular drugs and therapy, 1993, Volume: 7 Suppl 3 Topics: Adenosine Triphosphate; Animals; Electrophysiology; Guanidines; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Trypsin; Vasodilator Agents	1993
Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells. European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; Guanidines; In Vitro Techniques; Mice; Muscles; Niacinamide; Nicorandil; Organic Chemicals; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1993
Comparative electrophysiological and mechanical actions of ATP-sensitive potassium channel openers in canine Purkinje fibers. General pharmacology, 1993, Volume: 24, Issue:3 Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Electrophysiology; Glyburide; Guanidines; In Vitro Techniques; Myocardial Contraction; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Purkinje Fibers; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents	1993
K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America, 1993, Oct-15, Volume: 90, Issue:20 Topics: Alternative Splicing; Amyloid beta-Protein Precursor; Animals; Base Sequence; Benzopyrans; Brain Ischemia; Cell Death; Cromakalim; Gene Expression Regulation; Guanidines; Heat-Shock Proteins; Hippocampus; In Situ Hybridization; Male; Molecular Sequence Data; Neurons; Niacinamide; Nicorandil; Oligonucleotide Probes; Pinacidil; Potassium Channels; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrroles; Rats; Rats, Wistar; RNA, Messenger	1993
Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat. British journal of pharmacology, 1996, Volume: 117, Issue:4 Topics: Acidosis; Animals; Guanidines; Hypercapnia; Hypoxia; In Vitro Techniques; Lung; Male; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Pinacidil; Potassium Channel Blockers; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents	1996
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel. The Journal of physiology, 1997, Mar-15, Volume: 499 ( Pt 3) Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cloning, Molecular; Glyburide; Guanidines; Guanosine Diphosphate; Guanosine Triphosphate; Hypoglycemic Agents; KATP Channels; Macromolecular Substances; Magnesium; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Uridine Diphosphate; Vasodilator Agents	1997
Pinacidil but not nicorandil opens ATP-sensitive K+ channels and protects against simulated ischemia in rabbit myocytes. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:4 Topics: Adenosine Triphosphate; Animals; Cell Death; Disease Models, Animal; Electrophysiology; Female; Guanidines; Heart; Heart Ventricles; Male; Myocardial Ischemia; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Rabbits; Vasodilator Agents	1997
The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells. Pflugers Archiv : European journal of physiology, 1998, Volume: 435, Issue:5 Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Cell Line; Diazoxide; Guanidines; Humans; Membrane Potentials; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Uridine Diphosphate	1998
SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil. British journal of pharmacology, 1998, Volume: 124, Issue:5 Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Cell Line; Guanidines; Humans; Kidney; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Vasodilator Agents	1998
Nicorandil inhibits degranulation and TNF-alpha release from RBL-2H3 cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:4 Topics: Animals; beta-N-Acetylhexosaminidases; Calcium; Cell Degranulation; Cell Line; Cytoplasmic Granules; Cytosol; Dinitrophenols; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Hemoglobins; Indicators and Reagents; Mast Cells; Niacinamide; Nicorandil; Nitric Oxide; Nitric Oxide Donors; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Tumor Necrosis Factor-alpha	2002
Nicorandil inhibits the release of TNFalpha from a lymphocyte cell line and peripheral blood lymphocytes. International immunopharmacology, 2003, Volume: 3, Issue:12 Topics: B-Lymphocytes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Herpesvirus 4, Human; Humans; Immunoglobulin G; Leukocytes, Mononuclear; Niacinamide; Nicorandil; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Pinacidil; Potassium Channels; Quinoxalines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	2003