pinacidil has been researched along with indomethacin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Lundbeck, F; Sjögren, C | 1 |
| Cinquegrani, MP; Liang, CS | 1 |
| Kageyama, M; Matsumura, Y; Morimoto, S; Sasaki, Y; Takakuwa, T | 1 |
| Goodman, RP; Little, DM; Wright, JT | 1 |
| Kawashima, S; Liang, CS | 1 |
| Kalsner, S | 1 |
| El-Mahmoudy, A; Matsuyama, H; Shimizu, Y; Takewaki, T; Thapaliya, S | 1 |
| Blom, HJ; De Vriese, AS; Heil, SG; Kluijtmans, LA; Lameire, NH; Mortier, S; Van de Voorde, J | 1 |
| Ishii, K; Kametaka, S; Mori, A; Nakahara, T; Ogawa, N; Saito, M; Sakamoto, K | 1 |
| Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Suzuki, S | 1 |
| Balducci, J; Baumbach, J; Coonrod, DV; Garfield, RE; Shi, L; Shi, SQ | 1 |
1 trial(s) available for pinacidil and indomethacin
| Article | Year |
|---|---|
Antihypertensive effects of pinacidil in patients with and without indomethacin pretreatment.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Forearm; Guanidines; Heart Rate; Humans; Hypertension; Indomethacin; Male; Middle Aged; Pinacidil; Regional Blood Flow; Renal Circulation | 1988 |
16 other study(ies) available for pinacidil and indomethacin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
A pharmacological in vitro study of the mouse urinary bladder at the time of acute change in bladder reservoir function after irradiation.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Guanidines; In Vitro Techniques; Indomethacin; Mice; Muscle Contraction; Muscle, Smooth; Pinacidil; Scopolamine; Urinary Bladder | 1992 |
Diuretic effect induced by intrarenal infusion of pinacidil in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Bradykinin; Diuretics; Dogs; Glomerular Filtration Rate; Guanidines; Hydralazine; Indomethacin; Kidney; Phosphates; Pinacidil; Renal Circulation; Sodium; Vasodilator Agents | 1987 |
Inhibition of platelet aggregation and thromboxane production by pinacidil.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprost; Dinoprostone; Guanidines; Humans; In Vitro Techniques; Indomethacin; Pinacidil; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1985 |
Systemic and coronary hemodynamic effects of pinacidil, a new antihypertensive agent, in awake dogs: comparison with hydralazine.
Topics: Aminophylline; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Guanidines; Heart Rate; Hemodynamics; Hydrazines; Indomethacin; Pinacidil; Propranolol; Vascular Resistance | 1985 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Coronary Vessels; Glyburide; Guanidines; Hypoxia; In Vitro Techniques; Indomethacin; Muscle Relaxation; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Tetrodotoxin; Vasodilator Agents | 1995 |
An endothelium-derived factor modulates purinergic neurotransmission to mesenteric arterial smooth muscle of hamster.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Apamin; Biological Factors; Charybdotoxin; Cricetinae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mesocricetus; Muscle, Smooth, Vascular; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ouabain; Pinacidil; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Synaptic Transmission; Tetraethylammonium; Time Factors; Triazines; Uridine Triphosphate; Vasodilator Agents | 2003 |
Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia.
Topics: Acetylcholine; Acute Disease; Adenosine; Animals; Biological Factors; Chronic Disease; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Hyperhomocysteinemia; Indomethacin; Methionine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Renal Circulation; Vasodilation; Vitamin B Complex; Vitamin B Deficiency | 2004 |
Vasodilator effect of nicorandil on retinal blood vessels in rats.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Glyburide; Indomethacin; Male; Nicorandil; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pinacidil; Potassium Channel Blockers; Rats; Rats, Wistar; Retinal Vessels; Vasodilation; Vasodilator Agents | 2007 |
Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Fluorescein Angiography; Glucose; Heart Rate; Hyperglycemia; Indomethacin; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Peptides; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Retinal Artery; Vasodilation; Vasodilator Agents | 2011 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Premature; Pinacidil; Pregnancy; Progesterone; Tocolytic Agents; Uterine Contraction | 2012 |