Page last updated: 2024-08-16

pinacidil and hydrochlorothiazide

pinacidil has been researched along with hydrochlorothiazide in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Alaupovic, PA; Corder, CN; Furste, SS; Goldberg, MR; Price, MD1
Goldberg, MR; Rockhold, FW; Thompson, WL1
Dornseif, BE; Goldberg, MR; Offen, WW; Rockhold, FW1
Goldberg, MR; Offen, WW1
Byyny, RL; LoVerde, ME; Mitchell, WD; Nies, AS1

Trials

5 trial(s) available for pinacidil and hydrochlorothiazide

ArticleYear
Lipid and apolipoprotein levels during therapy with pinacidil combined with hydrochlorothiazide.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:1

    Topics: Adult; Antihypertensive Agents; Apolipoproteins; Double-Blind Method; Drug Therapy, Combination; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Pinacidil

1992
Beneficial effects of pinacidil on blood lipids: comparisons with prazosin and placebo in patients with hypertension. Pinacidil-Prazosin and Pinacidil-Placebo Research Groups, Lilly Research Laboratories.
    The Journal of laboratory and clinical medicine, 1989, Volume: 114, Issue:6

    Topics: Antihypertensive Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Guanidines; Humans; Hydrochlorothiazide; Pinacidil; Prazosin; Propranolol; Random Allocation; Risk Factors; Triglycerides

1989
Dose-effect and concentration-effect relationships of pinacidil and hydrochlorothiazide in hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:2

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Female; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Pinacidil

1989
Pinacidil with and without hydrochlorothiazide. Dose-response relationships from results of a 4 x 3 factorial design study.
    Drugs, 1988, Volume: 36 Suppl 7

    Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pinacidil; Random Allocation

1988
A double-blind, randomized, controlled trial comparing pinacidil to hydralazine in essential hypertension.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:1

    Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Epinephrine; Female; Guanidines; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Male; Middle Aged; Norepinephrine; Pinacidil; Propranolol; Random Allocation; Renin

1987

Other Studies

5 other study(ies) available for pinacidil and hydrochlorothiazide

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016