pinacidil and bay-k-8644

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Female; Guanidines; Hand; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Nimodipine; Pinacidil; Vasoconstriction; Veins

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Benzopyrans; Bradykinin; Calcimycin; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Cromakalim; Guanidines; Histamine; Pinacidil; Potassium; Potassium Channels; Pyrroles; Rubidium Radioisotopes

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Guanidines; Male; Muscles; Pinacidil; Rats; Rats, Sprague-Dawley; Vasomotor System

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Chloride; Dogs; Guanidines; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Norepinephrine; Ouabain; Pinacidil; Potassium Channels; Vasodilator Agents

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Analysis of Variance; Angiotensin II; Animals; Arterioles; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Diltiazem; Guanidines; In Vitro Techniques; Kidney; Microcirculation; Pinacidil; Potassium Channels; Rats; Renal Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart Atria; Heart Ventricles; Pinacidil; Propranolol; Vasodilator Agents

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Blockers; Cesium; Chlorides; Digoxin; Female; Guanidines; Guinea Pigs; Heart; Heart Rate; Male; Pinacidil; Stereoisomerism; Verapamil

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Corticosterone; Electric Stimulation; Ion Channel Gating; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pinacidil; Potassium Channels; Presynaptic Terminals; Pulmonary Artery; Rabbits; Synapses

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Antihypertensive Agents; Biliary Tract; Boron Compounds; Calcitonin Gene-Related Peptide; Calcium; Calcium Channel Agonists; Calcium Channels; Cholelithiasis; Cholestasis; Cholesterol; Electric Conductivity; Electric Stimulation; Female; Fluorescent Dyes; Gallbladder; Gallbladder Emptying; Guinea Pigs; Male; Muscle, Smooth; Patch-Clamp Techniques; Pinacidil; Potassium; Potassium Channels

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium Channel Agonists; Catecholamines; Dimethylphenylpiperazinium Iodide; Drug Interactions; Male; Minoxidil; Nicotinic Agonists; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Benzopyrans; Caesalpinia; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Indenes; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Phenylephrine; Pinacidil; Potassium Chloride; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-1 Receptor Agonists; Animals; Benzophenanthridines; Calcium Channel Agonists; Calcium Signaling; Carbenoxolone; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Gap Junctions; In Vitro Techniques; Male; Methacholine Chloride; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Pinacidil; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Riluzole; Ryanodine; Tetraethylammonium; Vasomotor System