pinacidil has been researched along with adenosine in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 25 (51.02) | 18.2507 |
| 2000's | 16 (32.65) | 29.6817 |
| 2010's | 8 (16.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chiba, S; Furukawa, Y; Karasawa, Y; Murakami, M; Ren, LM; Takayama, S | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Ogiwara, Y | 1 |
| Chang, JK; Heaton, J; Hyman, A; Lin, B; Lippton, H; Steinberg, S | 1 |
| Banitt, PF; Dai, HB; Friedman, M; Sellke, FW; Wang, SY | 1 |
| Bache, RJ; Duncker, DJ; Herrlinger, SK; Pavek, TJ; van Zon, NS | 1 |
| Chujo, M; Mohamed, MU; Mori, H; Nakazawa, H; Shinozaki, Y; Tanaka, E; Yamakawa, A | 1 |
| Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A; Ueno, H | 1 |
| Griffith, TM; Randall, MD; Ujiie, H | 1 |
| Hurt, CM; Pelleg, A; Wang, L; Xu, J | 1 |
| Kalsner, S | 1 |
| Gao, WD; Liu, Y; Marban, E; O'Rourke, B | 1 |
| Bache, RJ; Duncker, DJ; Ishibashi, Y; van Zon, NS | 1 |
| Belardinelli, L; Song, Y; Srinivas, M | 1 |
| Damon, DH; Lange, DL | 1 |
| Chiba, S; Furukawa, Y; Lakhe, M; Nagashima, Y; Yonezawa, T | 1 |
| Champion, HC; DeWitt, BJ; Giles, TD; Greenberg, SS; Kadowitz, PJ; Marrone, JR; McNamara, DB | 1 |
| Beresewicz, A; Maczewski, M | 1 |
| Damiano, RJ; Jayawant, AM | 1 |
| Liang, BT | 1 |
| Ma, L; Patterson, E; Robinson, CP; Thadani, U; Xiao, S; Yu, Z | 1 |
| Elliott, GT; Jacobson, KA; Liang, BT; Stambaugh, K | 1 |
| Isoda, T; Kass, DA; Pagliaro, P; Paolocci, N; Recchia, FA; Senzaki, H; Sunagawa, G | 1 |
| Foldes, FF; Matkó, I; Nagashima, H; Oe, K; Sántha, E; Sperlágh, B; Vizi, ES | 1 |
| Chambers, DJ; Hearse, DJ | 1 |
| Davie, CS; Everitt, DE; Standen, NB | 1 |
| Damiano, RJ; Ducko, CT; Hoenicke, EM; Peterseim, DS; Sun, X | 1 |
| Damiano, RJ; Hoenicke, EM; Strange, RG; Sun, X | 1 |
| Hein, TW; Kuo, L; Zhang, C | 1 |
| Li, Q; Puro, DG | 1 |
| Blom, HJ; De Vriese, AS; Heil, SG; Kluijtmans, LA; Lameire, NH; Mortier, S; Van de Voorde, J | 1 |
| Guan, YF; Miao, CY; Shen, FM; Su, DF; Zhu, GM | 1 |
| Damiano, RJ; Diodato, MD; Gaynor, SL; Lawton, JS; Prasad, SM; Shah, NR | 1 |
| Kogi, K; Konno, T; Nagai, A; Nakahata, N; Uchibori, T | 1 |
| Borne, J; Frame, MD; Mabanta, L; Valane, P | 1 |
| Damiano, RJ; Diodato, MD; Lawton, JS; Mizutani, S; Prasad, SM; Racen, EL; Shah, NR | 1 |
| Austin, C; Heagerty, AM; Izzard, AS; Lynch, FM | 1 |
| Fujita, R; Hirano, H; Kawasaki, S; Kimura, S; Matsumoto, M; Sasaki, K; Watanabe, N; Watanabe, S | 1 |
| Ishii, K; Mori, A; Nakahara, T; Nakazawa, T; Saito, M; Sakamoto, K | 1 |
| Gok, S; Izanli-Paksoy, A; Vural, K | 1 |
| Fukumoto, M; Ishizaki, E; Puro, DG | 1 |
| Han, P; Li, DJ; Liu, C; Shen, FM; Su, DF; Yang, YL; Yang, ZW | 1 |
| Li, T; Liu, L; Xu, J; Yang, G | 1 |
| Jamal Mustafa, S; Ledent, C; Nayeem, MA; Ponnoth, DS; Tilley, SL | 1 |
| Brennan, S; Hudman, D; Jackson, R; Lodwick, D; Norman, RI; Patel, M; Rainbow, RD; Sims, MW | 1 |
| An, JR; An, TG; Ha, KS; Han, ET; Hong, SH; Jeon, J; Kim, J; Lee, JM; Lee, SJ; Li, H; Na, SH; Park, WS; Seo, MS; Shin, SE; Yim, MJ | 1 |
1 review(s) available for pinacidil and adenosine
| Article | Year |
|---|---|
Developments in cardioprotection: "polarized" arrest as an alternative to "depolarized" arrest.
Topics: Adenosine; Animals; Cardioplegic Solutions; Electrocardiography; Heart Arrest, Induced; Humans; Myocardial Reperfusion Injury; Organ Preservation; Picolines; Pinacidil; Potassium Channels; Pyrans; Sodium Channel Blockers; Vasodilator Agents | 1999 |
48 other study(ies) available for pinacidil and adenosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Inhibition by glibenclamide of negative chronotropic and inotropic responses to pinacidil, acetylcholine, and adenosine in the isolated dog heart.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Depression, Chemical; Dogs; Glyburide; Guanidines; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Pinacidil; Potassium Channels; Vasodilator Agents | 1992 |
K+ channel blocking and anti-muscarinic effects of a novel piperazine derivative, INO 2628, on the isolated dog atrium.
Topics: Adenosine; Animals; Atrial Function; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart Atria; Myocardial Contraction; Niacinamide; Nicardipine; Nicorandil; Pinacidil; Piperazines; Potassium Channels; Time Factors | 1991 |
Pulmonary vasodilation to adrenomedullin: a novel peptide in humans.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adrenomedullin; Animals; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Guanidines; Humans; In Vitro Techniques; Injections, Intra-Arterial; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroglycerin; Peptide Fragments; Peptides; Pinacidil; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 1995 |
Myogenic and agonist induced responses of coronary venules after cold hyperkalaemic cardioplegia.
Topics: Adenosine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Cardiopulmonary Bypass; Coronary Vessels; Endothelium, Vascular; Female; Guanidines; Heart Arrest, Induced; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitroprusside; Pinacidil; Serotonin; Swine; Vasodilator Agents | 1995 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyperemia; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Nitroprusside; Oxygen Consumption; Physical Conditioning, Animal; Pinacidil; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Systole; Theophylline; Vasodilation | 1995 |
Modulation of adrenergic coronary vasoconstriction via ATP-sensitive potassium channel.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Coronary Circulation; Dogs; Electric Stimulation; Glyburide; Guanidines; Neuropeptide Y; Nitric Oxide; Norepinephrine; Peptide Fragments; Pinacidil; Potassium Channels; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1995 |
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Modulation of vasodilatation to levcromakalim by adenosine analogues in the rabbit ear: an explanation for hypoxic augmentation.
Topics: Adenosine; Animals; Arginine; Benzopyrans; Blood Pressure; Cromakalim; Drug Synergism; Ear, External; Guanidines; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pinacidil; Pyrroles; Rabbits; Regional Blood Flow; Vasodilation; Vasodilator Agents; Xanthines | 1994 |
Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Cardiac Pacing, Artificial; Cell Hypoxia; Glyburide; Guanidines; Guinea Pigs; Heart Conduction System; Myocardium; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Stereoisomerism; Theophylline | 1994 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Coronary Vessels; Glyburide; Guanidines; Hypoxia; In Vitro Techniques; Indomethacin; Muscle Relaxation; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Tetrodotoxin; Vasodilator Agents | 1995 |
Synergistic modulation of ATP-sensitive K+ currents by protein kinase C and adenosine. Implications for ischemic preconditioning.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Drug Synergism; Enzyme Activation; Guanidines; Myocardial Ischemia; Myocardium; Pinacidil; Potassium Channels; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1996 |
Role of K+ ATP channels and adenosine in the regulation of coronary blood flow during exercise with normal and restricted coronary blood flow.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Glyburide; Guanidines; Hemodynamics; Myocardial Contraction; Physical Exertion; Pinacidil; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents | 1996 |
Nonspecific inhibition of adenosine-activated K+ current by glibenclamide in guinea pig atrial myocytes.
Topics: Action Potentials; Adenosine; Animals; Atrial Function; Carbachol; Electric Conductivity; Glyburide; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Myocardium; Pinacidil; Potassium; Reaction Time | 1996 |
Transforming growth factor beta constricts rat cremaster arterioles.
Topics: Acetylcholine; Adenosine; Animals; Arachidonic Acid; Arterioles; Enzyme Inhibitors; Glyburide; Guanidines; Male; Meclofenamic Acid; Micromanipulation; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Transforming Growth Factor beta; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Chronotropic and inotropic effects of terikalant on isolated, blood-perfused atrial and ventricular preparations of dogs.
Topics: Acetylcholine; Adenosine; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Chromans; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanidines; Heart Rate; Male; Muscle Contraction; Norepinephrine; Pinacidil; Piperidines; Potassium Channels; Propranolol; Vasodilator Agents; Ventricular Function | 1997 |
Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
Topics: Acetylcholine; Adenosine; Adrenomedullin; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Endothelium, Vascular; Female; Guanidines; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Peptides; Pinacidil; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
The role of adenosine and ATP-sensitive potassium channels in the protection afforded by ischemic preconditioning against the post-ischemic endothelial dysfunction in guinea-pig hearts.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Pinacidil; Potassium Channel Blockers; Potassium Channels; Vasodilator Agents; Xanthines | 1998 |
The superiority of pinacidil over adenosine cardioplegia in blood-perfused isolated hearts.
Topics: Adenosine; Animals; Blood; Cardioplegic Solutions; Female; Glucose; Heart; Male; Membrane Potentials; Myocardial Reperfusion Injury; Perfusion; Pinacidil; Potassium Channels; Rabbits; Tromethamine; Vasodilator Agents | 1998 |
Protein kinase C-dependent activation of KATP channel enhances adenosine-induced cardioprotection.
Topics: Adenosine; Animals; Cells, Cultured; Chick Embryo; Enzyme Activation; Glyburide; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardium; Pinacidil; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Tetradecanoylphorbol Acetate | 1998 |
Supersensitivity to serotonin- and histamine-induced arterial contraction following ovariectomy.
Topics: Acetylcholine; Adenosine; Animals; Aorta, Thoracic; Coronary Vessels; Dose-Response Relationship, Drug; Epinephrine; Estradiol; Estrogen Replacement Therapy; Female; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Ovariectomy; Perfusion; Pinacidil; Potassium Chloride; Pressure; Rabbits; Sensitivity and Specificity; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Additive effects of late preconditioning produced by monophosphoryl lipid A and the early preconditioning mediated by adenosine receptors and KATP channel.
Topics: Adenosine; Animals; Cells, Cultured; Chick Embryo; Ischemic Preconditioning, Myocardial; Lipid A; Myocardium; omega-N-Methylarginine; Pinacidil; Potassium Channels; Purinergic P1 Receptor Agonists; Vasodilator Agents | 1999 |
Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusion in the dog.
Topics: Adenosine; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Diastole; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Myocardium; Oxygen Consumption; Perfusion; Pinacidil; Quinacrine; Systole; Vasodilator Agents; Verapamil | 1999 |
Modulation of norepinephrine release by ATP-dependent K(+)-channel activators and inhibitors in guinea-pig and human isolated right atrium.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Analysis of Variance; Animals; Clonidine; Cromakalim; Decanoic Acids; Diazoxide; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Heart Atria; Humans; Hydroxy Acids; In Vitro Techniques; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Pinacidil; Potassium Channel Blockers; Potassium Channels; Stimulation, Chemical; Sympathetic Nervous System | 1999 |
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1999 |
Donor heart preservation with the potassium channel opener pinacidil: comparison with University of Wisconsin and St. Thomas' solution.
Topics: Adenosine; Allopurinol; Animals; Bicarbonates; Calcium Chloride; Cold Temperature; Coronary Circulation; Glutathione; Heart Transplantation; In Vitro Techniques; Insulin; Magnesium; Organ Preservation; Organ Preservation Solutions; Pinacidil; Potassium Channels; Potassium Chloride; Rabbits; Raffinose; Sodium Chloride; Ventricular Function, Left | 2000 |
Donor heart preservation with a novel hyperpolarizing solution: superior protection compared with University of Wisconsin solution.
Topics: Adenosine; Allopurinol; Analysis of Variance; Animals; Cardioplegic Solutions; Glutathione; Heart Transplantation; Insulin; Organ Preservation; Organ Preservation Solutions; Pinacidil; Rabbits; Raffinose; Signal Processing, Computer-Assisted; Vasodilator Agents | 2000 |
Transmural difference in coronary arteriolar dilation to adenosine: effect of luminal pressure and K(ATP) channels.
Topics: Adenosine; Animals; Arterioles; Blood Pressure; Coronary Circulation; Endocardium; Endothelium, Vascular; Female; In Vitro Techniques; Male; Microcirculation; Muscle, Smooth, Vascular; Pericardium; Pinacidil; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 2000 |
Adenosine activates ATP-sensitive K(+) currents in pericytes of rat retinal microvessels: role of A1 and A2a receptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antimetabolites; Antimycin A; Eye Proteins; Glyburide; Iodoacetates; Ion Transport; Membrane Potentials; Microcirculation; Patch-Clamp Techniques; Pericytes; Pinacidil; Potassium; Potassium Channels; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retinal Vessels; Vasodilation; Vasodilator Agents | 2001 |
Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia.
Topics: Acetylcholine; Acute Disease; Adenosine; Animals; Biological Factors; Chronic Disease; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Hyperhomocysteinemia; Indomethacin; Methionine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Renal Circulation; Vasodilation; Vitamin B Complex; Vitamin B Deficiency | 2004 |
ATP-sensitive potassium channels are involved in adenosine-induced reduction of blood pressure variability in spontaneously hypertensive rats.
Topics: Adenosine; Animals; Blood Pressure; Male; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred SHR | 2004 |
Donor heart preservation with pinacidil: the role of the mitochondrial K ATP channel.
Topics: Adenosine; Allopurinol; Animals; Benzamides; Cardiotonic Agents; Coronary Circulation; Decanoic Acids; Drug Evaluation, Preclinical; Female; Glutathione; Heart; Heart Ventricles; Hydroxy Acids; Insulin; Ion Transport; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Organ Preservation; Organ Preservation Solutions; Pinacidil; Potassium Channels; Pressure; Rabbits; Raffinose; Random Allocation; Sarcolemma; Tissue and Organ Harvesting; Ventricular Function, Left | 2004 |
2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alkynes; Animals; Antihypertensive Agents; Caffeine; Decanoic Acids; Glyburide; Hydroxy Acids; Hypotonic Solutions; Intraocular Pressure; Male; Ocular Hypertension; Phenethylamines; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Receptor, Adenosine A2A; Sodium Chloride; Time Factors; Xanthines | 2005 |
Initiation of remote microvascular preconditioning requires K(ATP) channel activity.
Topics: Adenosine; Animals; Arginine; Arterioles; ATP-Binding Cassette Transporters; Bradykinin; Cricetinae; Cyclic GMP; Decanoic Acids; Diazoxide; Hydroxy Acids; Ischemic Preconditioning; KATP Channels; Male; Mesocricetus; Microcirculation; Nitric Oxide Donors; Nitroprusside; Pinacidil; Potassium Channels, Inwardly Rectifying; Signal Transduction; Vasodilation | 2006 |
Progress towards a more physiologic approach to donor heart preservation: the advantages of hyperpolarized arrest.
Topics: Adenosine; Allopurinol; Animals; Coronary Circulation; Female; Glutathione; Heart Transplantation; Insulin; Male; Membrane Potentials; Myocardial Contraction; Organ Preservation; Organ Preservation Solutions; Pinacidil; Rabbits; Raffinose; Vasodilator Agents; Ventricular Function, Left | 2005 |
Adenosine- and hypoxia-induced dilation of human coronary resistance arteries: evidence against the involvement of K(ATP) channels.
Topics: Adenosine; Aged; Cell Hypoxia; Coronary Vessels; Dilatation, Pathologic; Drug Interactions; Female; Glyburide; Humans; In Vitro Techniques; Male; Middle Aged; Pinacidil; Potassium Channels; Vasodilator Agents | 2006 |
Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Benzopyrans; Cromakalim; Cyclic AMP; Cyclopentanes; Enzyme Activation; Female; Follicle Stimulating Hormone; In Vitro Techniques; Ion Channel Gating; KATP Channels; Membrane Potentials; Ovarian Follicle; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Receptors, Drug; Receptors, Purinergic P2; Sulfonylurea Compounds; Sulfonylurea Receptors; Uridine Triphosphate; Xenopus laevis | 2007 |
Vasodilator effects of adenosine on retinal arterioles in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Blood Pressure; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glyburide; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pinacidil; Potassium Channel Blockers; Rats; Rats, Wistar; Retinal Vessels; Streptozocin; Vasodilation; Vasodilator Agents | 2008 |
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Benzophenanthridines; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; KATP Channels; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Pinacidil; Protein Kinase C; rhoA GTP-Binding Protein; Trachea | 2009 |
Functional K(ATP) channels in the rat retinal microvasculature: topographical distribution, redox regulation, spermine modulation and diabetic alteration.
Topics: Adenosine; Animals; Arterioles; Capillaries; Diabetes Mellitus, Experimental; Dithionitrobenzoic Acid; Dithiothreitol; Eflornithine; Electrophysiological Phenomena; Hydrogen Peroxide; KATP Channels; Membrane Potentials; Oxidation-Reduction; Perfusion; Pinacidil; Potassium; Rats; Rats, Long-Evans; Retinal Vessels; Spermine; Venules | 2009 |
Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats.
Topics: Adenosine; Animals; Aorta; Autonomic Denervation; Blood Pressure; Blotting, Western; Carotid Sinus; Dose-Response Relationship, Drug; KATP Channels; Male; Mesenteric Arteries; Pinacidil; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasodilator Agents | 2011 |
Pinacidil pretreatment improves vascular reactivity after shock through PKCα and PKCε in rats.
Topics: Adenosine; Animals; Calcium; Disease Models, Animal; Female; Fluid Therapy; Male; Mesenteric Artery, Superior; Pinacidil; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Receptor, Adenosine A1; Resuscitation; Shock, Hemorrhagic; Survival Rate; Vasodilator Agents; Xanthines | 2012 |
CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alcohol Oxidoreductases; Animals; Cromakalim; Decanoic Acids; Female; Glyburide; Hydroxy Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidoreductases; Phenethylamines; Pinacidil; Receptor, Adenosine A2A; Sarcolemma | 2012 |
Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection.
Topics: Action Potentials; Adenosine; Animals; Cardiotonic Agents; Cell Separation; Diazoxide; Enzyme Activation; Heart Failure; Ion Channel Gating; Ischemic Preconditioning, Myocardial; Isoenzymes; KATP Channels; Male; Myocardial Contraction; Myocardial Reperfusion; Myocytes, Cardiac; Phenotype; Pinacidil; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Rats, Wistar; Sarcolemma; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
Alterations of ATP-sensitive K
Topics: Adenosine; Adenosine Triphosphate; Arteries; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diabetes, Gestational; Female; Humans; KATP Channels; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pinacidil; Pregnancy; Signal Transduction | 2018 |