pimozide has been researched along with thioridazine in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (53.85) | 18.7374 |
| 1990's | 6 (9.23) | 18.2507 |
| 2000's | 17 (26.15) | 29.6817 |
| 2010's | 7 (10.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ellefson, CR; Kehr, JR; Miller, A; Woo, CM | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Butler, DE; DeWald, HA; Wise, LD | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Ikeda, K; Kobayashi, T; Kumanishi, T | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S | 1 |
| Pearlstein, R; Rampe, D; Vaz, R | 1 |
| Glennon, RA | 1 |
| Keserü, GM | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Hohlweg, R; Jeppesen, CB; Lau, JF; Rimvall, K | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Giordanetto, F; Leach, AG; Zachariae, U | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ahlenius, S; Engel, J | 1 |
| Cuparencu, F; Feszt, G; Kun, I; Orbán, I | 1 |
| Setler, P; Weidley, E; Zarevics, P | 1 |
| Fogelholm, R; Kotilainen, P; Lamberg, BA; Linnoila, M; Olkinuora, M; Saarinen, P | 1 |
| Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF | 1 |
| Obukhov, GA | 1 |
| Martin, IC | 1 |
| Costa, E; Guidotti, A; Revuelta, A; Zivkovic, B | 1 |
| Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F | 1 |
| Lechin, F; Van Der Dijs, B | 1 |
| Costall, B; Naylor, RJ | 2 |
| Fielding, S; Lal, H; Marky, M | 1 |
| Clark, ML; Costiloe, JP; Hill, D; Huber, WK; Wood, F | 1 |
| Kelly, PH; Miller, RJ | 1 |
| Fillmore, MT; Ruggles, JL; Taukulis, HK | 1 |
| Peterson, VA; Strobl, JS | 1 |
| Kirkwood, KL; Lantz, TK; Lewine, MA; Peterson, VA; Strobl, JS; Worley, JF | 1 |
| Jepsen, SA; Nielsen, EB | 1 |
| Muscat, R; Towell, A; Willner, P | 1 |
| Barnes, TR; Katona, CL | 1 |
| Koga, I; Nishikawa, T; Tanaka, M; Tsuda, A; Uchida, Y | 1 |
| Castro, JA; de Fenos, OM; de Ferreyra, EC | 1 |
| Monteiro, LM | 1 |
| Hiley, CR; Miller, RJ | 1 |
| Clemens, JA; Sawyer, BD; Smalstig, EB | 1 |
| Matthysse, S | 1 |
| Angrist, B; Gershon, S | 1 |
| Gershon, S; Klingenstein, RJ; Wallach, MB | 1 |
| Bartholini, G; Keller, HH; Pletscher, A | 1 |
| Angrist, B; Gershon, S; Rotrosen, J; Wallach, MB | 1 |
| Alloway, KD; Bashore, TR; Gelman, J; Rebec, GV | 1 |
| Luchins, DJ; Oliver, AP; Wyatt, RJ | 1 |
| MacDonald, C; Robertson, A | 1 |
| Smythies, JR | 1 |
| Bonaventura, S; Crews, WD; Hay, CL; Rowe, FB; Steele, WK | 1 |
| Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M | 1 |
4 review(s) available for pimozide and thioridazine
| Article | Year |
|---|---|
Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.
Topics: Cation Transport Proteins; DNA-Binding Proteins; Drug-Related Side Effects and Adverse Reactions; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Models, Molecular; Pharmaceutical Preparations; Potassium Channels; Potassium Channels, Voltage-Gated; Structure-Activity Relationship; Torsades de Pointes; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Dopamine and psychotic states: preliminary remarks.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carbon Radioisotopes; Cats; Cocaine; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Methylphenidate; Pemoline; Phenmetrazine; Pimozide; Psychoses, Substance-Induced; Psychotic Disorders; Rats; Receptors, Cell Surface; Species Specificity; Stereotyped Behavior; Thioridazine; Tyrosine | 1974 |
4 trial(s) available for pimozide and thioridazine
| Article | Year |
|---|---|
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine | 1975 |
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Long-Term Care; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pimozide; Placebos; Schizophrenia; Thioridazine; Trifluoperazine; Trifluperidol | 1975 |
Pimozide in chronic schizophrenic outpatients.
Topics: Adult; Ambulatory Care; Basal Ganglia Diseases; Chronic Disease; Consciousness Disorders; Drug Evaluation; Headache; Humans; Male; Middle Aged; Movement Disorders; Outpatient Clinics, Hospital; Pimozide; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Social Adjustment; Thioridazine | 1975 |
Prophylactic effects of neuroleptics in symptom-free schizophrenics: roles of dopaminergic and noradrenergic blockers.
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pimozide; Prolactin; Schizophrenia; Thioridazine | 1985 |
57 other study(ies) available for pimozide and thioridazine
| Article | Year |
|---|---|
Synthesis and biological evaluation of some 2-amino-4-aryl-3H-1,5-benzodiazepine analogues of clozapine.
Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Avoidance Learning; Brain; Clozapine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Rats | 1978 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
(1,3-Dialkyl-5-amino-1H-pyrazol-4-yl)arylmethanones. A series of novel central nervous system depressants.
Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Ketones; Male; Mice; Motor Activity; Posture; Pyrazoles; Structure-Activity Relationship | 1984 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dose-Response Relationship, Drug; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Haloperidol; Heart; Mice; Oocytes; Pimozide; Potassium Channels; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Thioridazine; Xenopus laevis | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG | 2002 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Ureas with histamine H3-antagonist receptor activity--a new scaffold discovered by lead-hopping from cinnamic acid amides.
Topics: Cinnamates; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine Antagonists; Humans; Molecular Structure; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship; Thiazines; Urea | 2006 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Potentiation by alpha-methyltyrosine of the suppression of food-reinforced lever-pressing behaviour induced by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Clozapine; Conditioning, Operant; Drug Synergism; Feeding Behavior; Haloperidol; Male; Methyltyrosines; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Thioridazine | 1977 |
The different influence of predominantly antiadrenergic and antidopaminergic neuroleptics on the estrous cycle in rats.
Topics: Animals; Chlorpromazine; Diestrus; Dose-Response Relationship, Drug; Estrus; Female; Fluspirilene; Methotrimeprazine; Phenothiazines; Pimozide; Pregnancy; Pseudopregnancy; Rats; Receptors, Adrenergic; Thioridazine; Tranquilizing Agents | 1977 |
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation; Male; Muscle Contraction; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Self Stimulation; Thioridazine; Time Factors | 1977 |
The effect of psychotropic drugs on the TSH-response to thyroliberin (TRH).
Topics: Chlorpromazine; Fusaric Acid; Humans; Levodopa; Norepinephrine; Pimozide; Pituitary Gland, Anterior; Propranolol; Psychotropic Drugs; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thioridazine; Thyrotropin; Thyrotropin-Releasing Hormone | 1977 |
[Prolonged action neuroleptics (review of the foreign literature)].
Topics: Acute Disease; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Child; Chronic Disease; Delayed-Action Preparations; Dibenzazepines; Dibenzothiepins; Dosage Forms; Drug Therapy, Combination; Fluphenazine; Humans; Paranoid Disorders; Perphenazine; Pimozide; Piperazines; Piperidines; Schizophrenia; Structure-Activity Relationship; Thioridazine; Thioxanthenes; Tranquilizing Agents | 1975 |
Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Catecholamines; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzothiepins; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothalamus; Kinetics; Male; Norepinephrine; Pimozide; Promethazine; Rats; Thioridazine; Tyrosine 3-Monooxygenase | 1975 |
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Homovanillic Acid; Humans; Limbic System; Male; Phenylacetates; Pimozide; Rats; Receptors, Drug; Rotation; Stereotyped Behavior; Substantia Nigra; Thioridazine | 1975 |
Effects of dopaminergic blocking agents on distal colon motility.
Topics: Adolescent; Adult; Biperiden; Colon; Dihydroergotamine; Dopamine Antagonists; Female; Gastrointestinal Motility; Haloperidol; Humans; Male; Middle Aged; Muscle Tonus; Pimozide; Sulpiride; Thioridazine | 1979 |
A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic systems.
Topics: Animals; Brain; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Fluphenazine; Haloperidol; Limbic System; Male; Metoclopramide; Pimozide; Rats; Stereotaxic Techniques; Sulpiride; Thioridazine; Tranquilizing Agents | 1976 |
Effect of neuroleptic drugs on mouse jumping induced by L-DOPA in amphetamine treated mice.
Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Levodopa; Male; Mice; Pimozide; Promethazine; Psychotropic Drugs; Stereotyped Behavior; Thioridazine; Tranquilizing Agents | 1976 |
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clopenthixol; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Methamphetamine; Models, Biological; Oxotremorine; Parasympathomimetics; Pimozide; Rats; Scopolamine; Substantia Nigra; Thioridazine; Tranquilizing Agents | 1975 |
Detection of the nueroleptic properties of clozapine, sulpiride and thioridazine.
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Synergism; Fluphenazine; Haloperidol; Humans; Isoquinolines; Male; Methyltyrosines; Pimozide; Rats; Spiro Compounds; Stereotyped Behavior; Succinimides; Sulpiride; Thioridazine; Tranquilizing Agents | 1975 |
Neuroleptic-induced changes in the anxiolytic and myorelaxant properties of diazepam in the rat.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Chlorpromazine; Diazepam; Drug Interactions; Haloperidol; Male; Muscle Relaxants, Central; Pimozide; Rats; Thioridazine | 1992 |
Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13.
Topics: Breast Neoplasms; Calmodulin; Cell Cycle; Cell Division; Drug Resistance; Flow Cytometry; Humans; Pimozide; Receptors, Estrogen; Sulfonamides; Thioridazine; Tumor Cells, Cultured | 1992 |
Inhibition of human breast cancer cell proliferation in tissue culture by the neuroleptic agents pimozide and thioridazine.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; Estradiol; Female; Humans; Kinetics; Pimozide; Thioridazine; Thymidine; Tumor Cells, Cultured | 1990 |
Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Cues; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Humans; Male; Metoclopramide; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Thioridazine | 1985 |
Behavioural microanalysis of the role of dopamine in amphetamine anorexia.
Topics: Animals; Anorexia; Apomorphine; Dextroamphetamine; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Feeding Behavior; Male; Pimozide; Rats; Rats, Inbred Strains; Reference Values; Thioridazine; Time Factors | 1988 |
Susceptibility to drug-induced hypotension in post-partum psychosis.
Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Pimozide; Pregnancy; Psychotic Disorders; Psychotropic Drugs; Puerperal Disorders; Thioridazine; Trifluoperazine | 1986 |
Late preventive effects of several anticalmodulin drugs on galactosamine-induced liver necrosis.
Topics: Animals; Calmodulin; Galactosamine; Imipramine; Liver; Male; Necrosis; Pimozide; Rats; Thioridazine; Trifluoperazine | 1985 |
Tardive dyskinesia controlled by anticholinergic agents.
Topics: Adolescent; Benztropine; Bromazepam; Dyskinesia, Drug-Induced; Humans; Lightning; Male; Parasympatholytics; Pimozide; Thioridazine | 1985 |
Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism.
Topics: Adenylyl Cyclase Inhibitors; Animals; Atropine; Azirines; Benzoates; Benztropine; Cerebral Cortex; Corpus Striatum; Dibenzazepines; Ethanol; Extrapyramidal Tracts; In Vitro Techniques; Kinetics; Male; Parasympatholytics; Phenothiazines; Pimozide; Piperazines; Rats; Receptors, Drug; Spiro Compounds; Thioridazine; Thioxanthenes; Tranquilizing Agents; Trifluoperazine; Tritium | 1974 |
Antipsychotic drugs stimulate prolactin release.
Topics: Animals; Chlorpromazine; Dopamine; Female; Fluphenazine; Haloperidol; Male; Phenothiazines; Pimozide; Prolactin; Promethazine; Rats; Receptors, Drug; Sex Factors; Stimulation, Chemical; Sulpiride; Thiethylperazine; Thioridazine; Tranquilizing Agents | 1974 |
Dopamine and the pharmacology of schizophrenia: the state of the evidence.
Topics: Amphetamine; Animals; Brain; Cats; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Haplorhini; Humans; Limbic System; Norepinephrine; Pimozide; Psychoses, Substance-Induced; Rats; Receptors, Drug; Schizophrenia; Species Specificity; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship; Thiethylperazine; Thioridazine | 1974 |
A comparison of pimozide and thioridazine as antagonists of amphetamine-induced stereotyped behavior in dogs.
Topics: Amphetamine; Animals; Behavior, Animal; Dogs; Female; Injections, Intramuscular; Male; Pimozide; Thioridazine | 1973 |
Increase of 3-methoxy-4-hydroxyphenylethylene glycol in rat brain by neuroleptic drugs.
Topics: Animals; Brain Chemistry; Chlorpromazine; Dibenzazepines; Dibenzothiepins; Dose-Response Relationship, Drug; Glycols; Haloperidol; Male; Methoxyhydroxyphenylglycol; Pimozide; Piperazines; Rats; Sulfides; Thioridazine; Tranquilizing Agents | 1973 |
Antagonism of apomorphine-induced sterotypy and emesis in dogs by thioridazine, haloperidol, and pimozide.
Topics: Animals; Apomorphine; Behavior, Animal; Blood-Brain Barrier; Chemoreceptor Cells; Corpus Striatum; Dogs; Drug Antagonism; Female; Haloperidol; Male; Pimozide; Premedication; Thioridazine; Time Factors; Tremor; Vomiting | 1972 |
Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat.
Topics: Action Potentials; Amygdala; Animals; Antipsychotic Agents; Catalepsy; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Neurons; Pimozide; Rats; Rats, Inbred Strains; Thioridazine | 1983 |
Neuroleptic-induced seizures. An in vitro technique for assessing relative risk.
Topics: Animals; Antipsychotic Agents; Butaclamol; Chlorpromazine; Culture Techniques; Dose-Response Relationship, Drug; Fluphenazine; Guinea Pigs; Haloperidol; Hippocampus; Male; Molindone; Pimozide; Seizures; Thioridazine | 1982 |
Atypical neuroleptics clozapine and thioridazine enhance amphetamine-induced stereotypy.
Topics: Animals; Clozapine; Dextroamphetamine; Dibenzazepines; Drug Interactions; Humans; Male; Motor Activity; Pimozide; Rats; Stereotyped Behavior; Thioridazine; Time Factors | 1984 |
An hypothesis of the molecular structure of the dopamine receptor.
Topics: Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Neurotensin; Pimozide; Receptors, Cholinergic; Receptors, Dopamine; Spiperone; Thioridazine | 1981 |
Gilles de la Tourette disorder among individuals with severe or profound mental retardation.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Education of Intellectually Disabled; Female; Humans; Intellectual Disability; Male; Middle Aged; Pimozide; Thioridazine; Tourette Syndrome | 1993 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine | 2005 |