Page last updated: 2024-08-22

pimozide and sertraline

pimozide has been researched along with sertraline in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bomberger, JM; Deschamps, JD; Flitter, BA; Freedman, CJ; Holman, TR; Jadhav, A; Jameson, JB; Maloney, DJ; Melvin, JA; Nguyen, JV; Ogunsola, AF; Simeonov, A; Yasgar, A1
Hollander, E; Josephson, SC; Stein, DJ1
Buckingham, D; Gaffney, G1
Drummer, OH; Gall, J; King, CV; McIntyre, IM; Staikos, V1
Desta, Z; Flockhart, DA1
Alderman, J1
Kenchaiah, BK; Kumar, S; Tharyan, P1
Arakawa, H; Ishii, M; Ito, MA; Mizoi, K; Morishita, H; Ogihara, T; Okawa, K; Yano, K1
Ito, MA; Mizoi, K; Morishita, H; Ogihara, T; Perera, LMB; Yano, K; Zhang, X1

Reviews

1 review(s) available for pimozide and sertraline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for pimozide and sertraline

ArticleYear
Coadministration of sertraline with cisapride or pimozide: an open-label, nonrandomized examination of pharmacokinetics and corrected QT intervals in healthy adult volunteers.
    Clinical therapeutics, 2005, Volume: 27, Issue:7

    Topics: Adult; Cisapride; Dopamine Antagonists; Drug Interactions; Electrocardiography; Female; Humans; Male; Pimozide; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sertraline

2005

Other Studies

14 other study(ies) available for pimozide and sertraline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.
    Biochemistry, 2016, 06-14, Volume: 55, Issue:23

    Topics: Amino Acid Sequence; Animals; Antibody Formation; Arachidonate 15-Lipoxygenase; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Lipoxygenase Inhibitors; Pseudomonas aeruginosa; Rabbits; Substrate Specificity

2016
Serotonin reuptake blockers for the treatment of obsessional jealousy.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:1

    Topics: 1-Naphthylamine; Adult; Clomipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Jealousy; Male; Obsessive-Compulsive Disorder; Pimozide; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline

1994
New TS treatment.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:1

    Topics: 1-Naphthylamine; Adolescent; Female; Haloperidol; Humans; Pimozide; Selective Serotonin Reuptake Inhibitors; Sertraline; Tourette Syndrome

1993
A fatality involving moclobemide, sertraline, and pimozide.
    Journal of forensic sciences, 1997, Volume: 42, Issue:5

    Topics: 1-Naphthylamine; Adult; Antidepressive Agents; Antipsychotic Agents; Benzamides; Chromatography, High Pressure Liquid; Drug Interactions; Fatal Outcome; Humans; Liver; Lung; Male; Moclobemide; Pimozide; Polypharmacy; Sertraline

1997
Commentary on McIntyre IM, King CV, Staikos V, Gall J, Drummer OH. A fatality involving moclobemide, sertraline and pimozide. J Forensic Sci 1997;42:951-53.
    Journal of forensic sciences, 1999, Volume: 44, Issue:1

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Benzamides; Fatal Outcome; Humans; Male; Moclobemide; Pimozide; Sertraline

1999
Atypical anti-psychotics in delusional parasitosis: a retrospective case series of 20 patients.
    International journal of dermatology, 2010, Volume: 49, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Ectoparasitic Infestations; Female; Fluoxetine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Olanzapine; Pimozide; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Sertraline

2010
Gastrointestinal absorption of pimozide is enhanced by inhibition of P-glycoprotein.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: Animals; Aripiprazole; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Drug Interactions; Gastrointestinal Absorption; Humans; LLC-PK1 Cells; Pimozide; Sertraline; Swine

2020
P-Glycoprotein-Mediated Pharmacokinetic Interactions Increase Pimozide hERG Channel Inhibition.
    Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:12

    Topics: Antipsychotic Agents; Aripiprazole; ATP Binding Cassette Transporter, Subfamily B; Humans; Male; Pimozide; Potassium Channel Blockers; Sertraline

2022