Page last updated: 2024-08-22

pimozide and perphenazine

pimozide has been researched along with perphenazine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's1 (5.26)18.2507
2000's6 (31.58)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Topliss, JG; Yoshida, F1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Glennon, RA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Jackson, DM1
Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF1
Obukhov, GA1
Ben-David, M; Kramer, J1
Lamberts, SW; MacLeod, RM1
Schreiber, V1
Rolinski, Z; Scheel-Krüger, J1
Lehmeyer, JE; MacLeod, RM1

Reviews

2 review(s) available for pimozide and perphenazine

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for pimozide and perphenazine

ArticleYear
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine

1975

Other Studies

16 other study(ies) available for pimozide and perphenazine

ArticleYear
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Beta-phenylethylamine and locomotor activity in mice. Interaction with catecholaminergic neurones and receptors.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:4

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Ditiocarb; Drug Interactions; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Neurons; Perphenazine; Phenethylamines; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Drug; Reserpine

1975
[Prolonged action neuroleptics (review of the foreign literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:2

    Topics: Acute Disease; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Child; Chronic Disease; Delayed-Action Preparations; Dibenzazepines; Dibenzothiepins; Dosage Forms; Drug Therapy, Combination; Fluphenazine; Humans; Paranoid Disorders; Perphenazine; Pimozide; Piperazines; Piperidines; Schizophrenia; Structure-Activity Relationship; Thioridazine; Thioxanthenes; Tranquilizing Agents

1975
Prolactin suppression by (-) delta-9-tetrahydrocannabinol (THC): involvement of serotonergic and dopaminergic pathways.
    Endocrinology, 1978, Volume: 103, Issue:2

    Topics: Animals; Cyproheptadine; Dopamine; Dronabinol; Male; Perphenazine; Pimozide; Prolactin; Rats; Serotonin

1978
Effects of cyproheptadine on prolactin synthesis and release by normal and suppressed pituitary glands and by dispersed pituitary tumor cells.
    Endocrinology, 1978, Volume: 103, Issue:5

    Topics: Animals; Cyproheptadine; Female; Haloperidol; Male; Methysergide; Perphenazine; Pimozide; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats

1978
Dopaminergic control of adenohypophyseal growth.
    Voprosy biokhimii mozga, 1978, Volume: 13

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Ceruloplasmin; Dopamine; Drug Interactions; Estrogens; Perphenazine; Pimozide; Pituitary Gland, Anterior; Rats; Thyroxine

1978
The effect of dopamine and noradrenaline antagonists on amphetamine induced locomotor activity in mice and rats.
    Acta pharmacologica et toxicologica, 1973, Volume: 33, Issue:5

    Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Aza Compounds; Behavior, Animal; Depression, Chemical; Dopamine Antagonists; Dopamine beta-Hydroxylase; Ergotamine; Female; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Perphenazine; Phenoxybenzamine; Phenyl Ethers; Pimozide; Piperidines; Rats; Receptors, Drug; Spiro Compounds; Time Factors; Tranquilizing Agents; Trifluoperazine

1973
Restoration of prolactin synthesis and release by the administration of monoaminergic blocking agents to pituitary tumor-bearing rats.
    Cancer research, 1974, Volume: 34, Issue:2

    Topics: Animals; Dopamine; Dopamine Antagonists; Female; Haloperidol; In Vitro Techniques; Leucine; Male; Neoplasms, Experimental; Perphenazine; Pimozide; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Tritium

1974