Page last updated: 2024-08-22

pimozide and morphine

pimozide has been researched along with morphine in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199035 (71.43)18.7374
1990's6 (12.24)18.2507
2000's5 (10.20)29.6817
2010's3 (6.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A1
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
McGilliard, KL; Takemori, AE1
Chan, SH1
Paalzow, G1
Korf, J; Westerink, BH1
Chan, SH; Lee, CM; Wong, PC1
Gianutsos, G; Lal, H; Puri, SK1
Amit, Z; Sklar, LS1
French, ED; George, R; Vasquez, SA1
Overstreet, DH; Smee, ML1
Cuparencu, B; Sandor, V1
Ary, M; Cox, B; Lomax, P2
Estler, CJ; Fulle, P1
Overstreet, DH; Smee, ML; Woolston, ME1
Ary, M; Lomax, P1
Sparber, SB; Takemori, AE; Tulunay, FC1
Pert, CB; Snyder, SH1
Carol, M; Jacquet, YF; Russell, IS1
Henry, DJ; Rompré, PP; White, FJ; Wise, RA1
Franklin, KB; Morgan, MJ1
Agmo, A; Berenfeld, R1
Stewart, J; Vezina, P2
Rompré, PP; Wise, RA2
Bardo, MT; Neisewander, JL1
Baby, N; Jhamandas, K; Obonsawin, MC; Shin, SH; Van Vugt, DA1
Maickel, RP; Spratto, GR; Tocco, DR1
Gala, RR; Haisenleder, DJ1
Holmes, LJ; Wise, RA1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A1
Jacobs, BL1
Ratner, A; Torres, K; Woo, W; Yelvington, D1
Kameyama, T; Nagasaka, M1
Farris, TS; Richards, GE1
Jaju, BP; Srivastava, YP1
Bozarth, MA; Holmes, LJ; Wise, RA1
Brady, RC; Brownstein, BL; Connor, CG1
Leeb, K; Parker, L1
Huston-Lyons, D; Kornetsky, C; Sarkar, M1
Azizi, N; Rezayat, M; Zarrindast, MR1
Abbott, FV; Saddi, GM1

Reviews

1 review(s) available for pimozide and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

48 other study(ies) available for pimozide and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The effect of dopaminergic modifiers on morphine-induced analgesia and respiratory depression.
    European journal of pharmacology, 1979, Feb-15, Volume: 54, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Dopamine; Drug Interactions; Haloperidol; Levodopa; Male; Mice; Morphine; Pimozide; Reaction Time; Respiration

1979
Central neurotransmitter systems in the morphine suppression of jaw-opening reflex in rabbits: the dopaminergic system.
    Experimental neurology, 1979, Volume: 65, Issue:3

    Topics: Animals; Apomorphine; Dopamine; Dopamine Antagonists; Haloperidol; Jaw; Morphine; Neurotransmitter Agents; Pain; Physostigmine; Pimozide; Rabbits; Reflex

1979
Naloxone antagonizes theophylline-induced potentiation of morphine inhibition of a nociceptive reaction in rats.
    Psychopharmacology, 1979, Apr-25, Volume: 62, Issue:3

    Topics: Analgesics; Animals; Drug Interactions; Electric Stimulation; Male; Morphine; Naloxone; Pimozide; Rats; Theophylline; Time Factors; Vocalization, Animal

1979
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl

1975
The involvement of dopaminergic neurotransmission in the inhibitory effect of morphine on caudate neurone activities.
    Neuropharmacology, 1977, Volume: 16, Issue:9

    Topics: Animals; Caudate Nucleus; Dopamine; Electric Stimulation; Haloperidol; Male; Microelectrodes; Morphine; Naloxone; Neurons; Pimozide; Rats; Substantia Nigra; Synaptic Transmission; Time Factors

1977
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting

1975
Manipulations of catecholamine systems block the conditioned taste aversion induced by self-administered drugs.
    Neuropharmacology, 1977, Volume: 16, Issue:10

    Topics: Animals; Avoidance Learning; Cannabinoids; Catecholamines; Chlorides; Conditioning, Operant; Ethanol; Lithium; Male; Methyltyrosines; Morphine; Pimozide; Rats; Reinforcement, Psychology; Taste

1977
Potentiation of morphine hyperthermia in cats by pimozide and fluoxetine hydrochloride.
    European journal of pharmacology, 1978, Apr-15, Volume: 48, Issue:4

    Topics: Animals; Body Temperature; Cats; Drug Synergism; Fever; Male; Morphine; Phenyl Ethers; Pimozide; Propylamines; Receptors, Dopamine; Serotonin Antagonists

1978
Alterations in the effects of dopamine agonists and antagonists on general activity in rats following chronic morphine treatment.
    Psychopharmacology, 1976, Sep-17, Volume: 49, Issue:2

    Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Haloperidol; Male; Morphine; Motor Activity; Pimozide; Rats; Time Factors

1976
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol

1977
Dopaminergic involvement in withdrawal hypothermia and thermoregulatory behavior in morphine dependent rats.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Dopamine; Drug Implants; Humans; Male; Morphine; Morphine Dependence; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Time Factors

1976
Effects of antagonists of adrenaline recepotrs and dopamine receptors and dopamine receptors on morphine-stimulated glycogen breakdown in mouse brain.
    Journal of neurochemistry, 1976, Volume: 27, Issue:2

    Topics: Animals; Brain; Glycogen; Male; Mice; Morphine; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Adrenergic

1976
Dose-response shifts in the behavioural effects of dopamine agonists and antagonists following chronic morphine treatment.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Dopamine; Dopamine Antagonists; Drug Tolerance; Haloperidol; Humans; Male; Morphine; Motor Activity; Pimozide; Rats; Stereotyped Behavior; Time Factors

1976
Dopaminergic sites involved in morphine withdrawal hypothermia.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Implants; Humans; Hypothalamus; Injections; Male; Morphine; Naloxone; Pimozide; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome

1976
Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Animals; Apomorphine; Dopamine; Humans; Hypothermia; Male; Morphine; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
The effect of dopaminergic stimulation and blockade on the nociceptive and antinociceptive responses of mice.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Analgesics; Animals; Apomorphine; Depression, Chemical; Dopamine; Haloperidol; Levodopa; Male; Mice; Morphine; Naloxone; Pain; Pimozide; Reaction Time; Receptors, Drug; Stimulation, Chemical

1975
Identification of opiate receptor binding in intact animals.
    Life sciences, 1975, May-15, Volume: 16, Issue:10

    Topics: Animals; Binding Sites; Brain; Cerebellum; Cold Temperature; Corpus Striatum; Ether; Haloperidol; Male; Morphine; Nalorphine; Naloxone; Pentobarbital; Pimozide; Rats; Receptors, Drug; Sodium Chloride

1975
Morphine-induced rotation in naive, nonlesioned rats.
    Science (New York, N.Y.), 1976, Apr-16, Volume: 192, Issue:4236

    Topics: Analgesia; Animals; Atropine; Behavior, Animal; Dopamine; Locomotion; Male; Morphine; Motor Activity; Norepinephrine; Phentolamine; Pimozide; Propranolol; Rats; Reticular Formation

1976
Acute depolarization block of A10 dopamine neurons: interactions of morphine with dopamine antagonists.
    Brain research, 1992, Nov-20, Volume: 596, Issue:1-2

    Topics: Analysis of Variance; Animals; Benzazepines; Dopamine; Dopamine Antagonists; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Injections, Intravenous; Iontophoresis; Male; Morphine; Neurons; Pimozide; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali

1992
Dopamine receptor subtypes and formalin test analgesia.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Benzazepines; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Flupenthixol; Formaldehyde; Male; Morphine; Pain; Pimozide; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2

1991
Reinforcing properties of ejaculation in the male rat: role of opioids and dopamine.
    Behavioral neuroscience, 1990, Volume: 104, Issue:1

    Topics: Animals; Arousal; Brain; Dopamine; Ejaculation; Endorphins; Male; Morphine; Motivation; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Receptors, Opioid; Sexual Behavior, Animal; Social Environment

1990
The effect of dopamine receptor blockade on the development of sensitization to the locomotor activating effects of amphetamine and morphine.
    Brain research, 1989, Oct-09, Volume: 499, Issue:1

    Topics: Amphetamine; Animals; Benzazepines; Dopamine Antagonists; Isoquinolines; Male; Morphine; Motor Activity; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride

1989
Opioid-neuroleptic interaction in brainstem self-stimulation.
    Brain research, 1989, Jan-16, Volume: 477, Issue:1-2

    Topics: Animals; Brain Stem; Drug Interactions; Morphine; Naloxone; Organ Specificity; Pimozide; Rats; Reference Values; Self Stimulation

1989
Behavioral evidence for midbrain dopamine depolarization inactivation.
    Brain research, 1989, Jan-16, Volume: 477, Issue:1-2

    Topics: Animals; Dopamine; Drug Interactions; Electric Stimulation; Mesencephalon; Morphine; Muscimol; Pimozide; Rats; Reward; Self Stimulation

1989
Expression of morphine-conditioned hyperactivity is attenuated by naloxone and pimozide.
    Psychopharmacology, 1987, Volume: 93, Issue:3

    Topics: Animals; Conditioning, Classical; Hyperkinesis; Male; Morphine; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid

1987
Morphine can stimulate prolactin release independent of a dopaminergic mechanism.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:11

    Topics: Animals; Male; Morphine; Naloxone; Pimozide; Prolactin; Prolactin Release-Inhibiting Factors; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thyrotropin-Releasing Hormone

1988
Differential analgetic actions of amphetamine enantiomers in the mouse: a drug-drug interaction study.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Dextroamphetamine; Dopamine; Drug Interactions; Fenclonine; Fluoxetine; Male; Metergoline; Mice; Morphine; Naloxone; Norepinephrine; Pimozide; Serotonin; Stereoisomerism

1985
Hyperthermia induced by morphine administration to the VTA of the rat brain: an effect dissociable from morphine-induced reward and hyperactivity.
    Life sciences, 1985, Mar-18, Volume: 36, Issue:11

    Topics: Animals; Body Temperature Regulation; Fever; Male; Metergoline; Morphine; Motor Activity; Naloxone; Phenoxybenzamine; Pimozide; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Serotonin; Scopolamine; Stereotaxic Techniques; Tegmentum Mesencephali

1985
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone.
    Neuroendocrinology, 1986, Volume: 43, Issue:2

    Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics

1986
Contralateral circling induced by tegmental morphine: anatomical localization, pharmacological specificity, and phenomenology.
    Brain research, 1985, Feb-04, Volume: 326, Issue:1

    Topics: Animals; Locomotion; Male; Morphine; Motor Activity; Muscimol; Naltrexone; Pimozide; Rats; Rotation; Substantia Nigra; Tegmentum Mesencephali

1985
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus

1974
Effect of two dopamine receptor blockers on a serotonin-mediated behavioral syndrome in rats.
    European journal of pharmacology, 1974, Volume: 27, Issue:3

    Topics: Animals; Behavior, Animal; Benzoates; Dopamine; Dose-Response Relationship, Drug; Humans; Injections, Intraperitoneal; Locomotion; Male; Morphine; Motor Activity; Pargyline; Pimozide; Rats; Receptors, Drug; Serotonin; Spiro Compounds; Stereotyped Behavior; Tryptophan

1974
Effect of lergotrile mesylate and methysergide on morphine induced increase in prolactin release.
    Proceedings of the Western Pharmacology Society, 1981, Volume: 24

    Topics: Animals; Dopamine; Drug Interactions; Ergolines; Female; Methysergide; Morphine; Pimozide; Prolactin; Rats; Receptors, Dopamine

1981
A mode of action of morphine on a quickly learned conditioned suppression in mice.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:3

    Topics: alpha-Methyltyrosine; Animals; Atropine; Biogenic Amines; Conditioning, Operant; Drug Interactions; Electric Stimulation; Fenclonine; Haloperidol; Male; Methyltyrosines; Mice; Morphine; Phenoxybenzamine; Pimozide; Propranolol; Reserpine

1984
Morphine acts through alpha adrenergic and serotoninergic neurons to stimulate growth hormone secretion in the dog.
    Life sciences, 1980, Oct-06, Volume: 27, Issue:14

    Topics: Animals; Dogs; Growth Hormone; Haloperidol; Male; Metergoline; Morphine; Phentolamine; Pimozide; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin

1980
A study of dopaminergic mechanism in morphine induced Straub tail response.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:8

    Topics: Amphetamine; Animals; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Female; Haloperidol; Male; Mice; Morphine; Muscle Spasticity; Pimozide; Tail

1984
Circling from intracranial morphine applied to the ventral tegmental area in rats.
    Brain research bulletin, 1983, Volume: 11, Issue:3

    Topics: Animals; Brain Mapping; Dopamine; Drug Interactions; Male; Morphine; Motor Activity; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Tegmentum Mesencephali

1983
Trifluoperazine inhibits spreading and migration of cells in culture.
    Journal of cellular physiology, 1981, Volume: 108, Issue:3

    Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cell Adhesion; Cell Movement; Cells, Cultured; Chlorpromazine; Fibronectins; Membrane Fluidity; Morphine; Pimozide; Rats; Trifluoperazine

1981
Amphetamine-induced modification of quinine palatability: analysis by the taste reactivity test.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Dextroamphetamine; Drinking Behavior; Male; Morphine; Motor Activity; Naltrexone; Pimozide; Quinine; Rats; Rats, Sprague-Dawley; Sucrose; Taste

1994
Nicotine and brain-stimulation reward: interactions with morphine, amphetamine and pimozide.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2

    Topics: Amphetamine; Animals; Brain; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Medial Forebrain Bundle; Morphine; Nicotine; Pimozide; Rats; Rats, Inbred F344; Reward; Self Stimulation

1993
On the mechanism(s) of cholecystokinin (CCK): receptor stimulation attenuates morphine dependence in mice.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:3

    Topics: Adrenergic Antagonists; Animals; Atropine; Benzazepines; Ceruletide; Dopamine Antagonists; Male; Methysergide; Mice; Morphine; Morphine Dependence; Movement Disorders; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Cholecystokinin; Serotonin Antagonists; Sincalide; Substance Withdrawal Syndrome; Sulpiride

1997
The formalin test in the mouse: a parametric analysis of scoring properties.
    Pain, 2000, Dec-15, Volume: 89, Issue:1

    Topics: Acepromazine; Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Dipyrone; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Indomethacin; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Pain Measurement; Pentobarbital; Pimozide; Sensitivity and Specificity; Xylazine

2000