Page last updated: 2024-08-22

pimozide and fluspirilene

pimozide has been researched along with fluspirilene in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199010 (32.26)18.7374
1990's5 (16.13)18.2507
2000's8 (25.81)29.6817
2010's7 (22.58)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Butler, DE; Coughenour, LL; DeWald, HA; Lewis, EP; Lobbestael, SJ; Nordin, IC; Pattison, IC; Poschel, BP; Wise, LD1
Andrews, PR; Craik, DJ; Martin, JL1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellman, K; Knegtel, RM; Settimo, L1
Mowrey, DD; Sun, T; Tang, P; Tillman, TS; Wells, MM; Xu, Y1
Bomberger, JM; Deschamps, JD; Flitter, BA; Freedman, CJ; Holman, TR; Jadhav, A; Jameson, JB; Maloney, DJ; Melvin, JA; Nguyen, JV; Ogunsola, AF; Simeonov, A; Yasgar, A1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Cuparencu, F; Feszt, G; Kun, I; Orbán, I1
Carroll, BJ; Katz, RJ1
Reilly, TM1
Pluym, A1
König, L; Lange, E1
Biagi, BA; Day, RN; Enyeart, JJ; Maurer, RA; Sheu, SS1
Caliari, S; Casamenti, F; Moneti, G; Moroni, F; Pepeu, G; Pisani, G1
Pedata, F; Pepeu, G; Sorbi, S1
Lackington, I; Orrego, F1
de Lima, MC; Oliveira, CR; Sarmento, AB1
Inoue, K; Ito, K; Koizumi, S; Nakazawa, K; Ohno, Y1
Crumb, WJ; Murawsky, MK; Rampe, D; Wible, B1
Brown, C; Klein-Stevens, CL; Liang, L; White, J; Zhu, N1
Degtiar, VIe; Naid'onov, VG; Osypenko, VM; Shuba, IaM1
Degtiar, VE; Naidenov, VG; Osipenko, VN; Shuba, YM; Woosley, RL1
Habricot, Y; Jeannette, E; Maldiney, R; Miginiac, E; Paradis, S; Rona, JP; Zalejski, C1
Enyeart, JA; Enyeart, JJ1
Abou Farraj, R; Al Batran, R; Chahade, JJ; Chan, JSF; Crawford, PA; Eaton, F; Glover, JNM; Gopal, K; Greenwell, AA; Lee, C; Saed, CT; Tabatabaei Dakhili, SA; Ussher, JR; Velázquez-Martínez, CA; Yang, K1

Other Studies

31 other study(ies) available for pimozide and fluspirilene

ArticleYear
1-[3-(Diarylamino)propyl]piperidines and related compounds, potential antipsychotic agents with low cataleptogenic profiles.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Catalepsy; Corpus Striatum; Haloperidol; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Receptors, Dopamine; Self Stimulation; Structure-Activity Relationship

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain.
    Journal of medicinal chemistry, 2015, Apr-09, Volume: 58, Issue:7

    Topics: Analgesics, Non-Narcotic; Animals; Binding Sites; Cannabinoids; Drug Evaluation, Preclinical; Female; Lipids; Molecular Dynamics Simulation; Molecular Targeted Therapy; Nuclear Magnetic Resonance, Biomolecular; Oocytes; Pain; Protein Conformation; Protein Structure, Tertiary; Receptors, Glycine; Reproducibility of Results; Xenopus laevis

2015
Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.
    Biochemistry, 2016, 06-14, Volume: 55, Issue:23

    Topics: Amino Acid Sequence; Animals; Antibody Formation; Arachidonate 15-Lipoxygenase; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Lipoxygenase Inhibitors; Pseudomonas aeruginosa; Rabbits; Substrate Specificity

2016
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
The different influence of predominantly antiadrenergic and antidopaminergic neuroleptics on the estrous cycle in rats.
    Pharmacology, 1977, Volume: 15, Issue:2

    Topics: Animals; Chlorpromazine; Diestrus; Dose-Response Relationship, Drug; Estrus; Female; Fluspirilene; Methotrimeprazine; Phenothiazines; Pimozide; Pregnancy; Pseudopregnancy; Rats; Receptors, Adrenergic; Thioridazine; Tranquilizing Agents

1977
Enkephalin-dopamine interactions in behavioral arousal.
    Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4

    Topics: Animals; Behavior, Animal; Catecholamines; Dopamine Agents; Dopamine Antagonists; Enkephalins; Fluspirilene; Imidazolines; Male; Mice; Pimozide; Receptors, Dopamine

1979
Central dopamine blockade in anorexia nervosa.
    British medical journal, 1978, Feb-11, Volume: 1, Issue:6109

    Topics: Anorexia; Feeding and Eating Disorders; Fluspirilene; Humans; Pimozide; Receptors, Dopamine; Spiro Compounds; Synaptic Transmission

1978
TLC differentiation of butyrophenone and diphenylbutylpiperidine compounds from phenothiazine derivatives.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:8

    Topics: Butyrophenones; Chromatography, Thin Layer; Fluspirilene; Indicators and Reagents; Penfluridol; Phenothiazines; Pimozide; Piperidines

1979
[Significance and advantages of Orap in the ambulatory care of schizophrenic psychoses].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Cyclothymic Disorder; Depression; Depressive Disorder, Major; Female; Fluphenazine; Fluspirilene; Haloperidol; Humans; Male; Middle Aged; Penfluridol; Pimozide; Remission, Spontaneous; Schizophrenia; Therapeutic Equivalency

1976
Blockade of low and high threshold Ca2+ channels by diphenylbutylpiperidine antipsychotics linked to inhibition of prolactin gene expression.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cell Line; Fluspirilene; Gene Expression; Kinetics; Luciferases; Membrane Potentials; Penfluridol; Pimozide; Piperidines; Pituitary Neoplasms; Prolactin; Recombinant Fusion Proteins; Spiro Compounds; Thyrotropin-Releasing Hormone

1990
Acetylcholine and amino acid neurotransmitters in epidural cups of freely moving rats: effect of acute and chronic treatment with antischizophrenic drugs.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Acetylcholine; Amino Acids; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Fluspirilene; gamma-Aminobutyric Acid; Glutamates; Haloperidol; Male; Neurotransmitter Agents; Pimozide; Rats; Time Factors

1980
Choline high-affinity uptake and metabolism and choline acetyltransferase activity in the striatum of rats chronically treated with neuroleptics.
    Journal of neurochemistry, 1980, Volume: 35, Issue:3

    Topics: Animals; Antipsychotic Agents; Choline; Choline O-Acetyltransferase; Corpus Striatum; Fluspirilene; Haloperidol; In Vitro Techniques; Male; Pimozide; Rats; Synaptosomes; Time Factors

1980
Inhibition of calcium-activated potassium conductance of human erythrocytes by calmodulin inhibitory drugs.
    FEBS letters, 1981, Oct-12, Volume: 133, Issue:1

    Topics: Adenosine Triphosphatases; Ca(2+) Mg(2+)-ATPase; Calcimycin; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calmodulin; Erythrocyte Membrane; Erythrocytes; Fluspirilene; Humans; Kinetics; Penfluridol; Phenothiazines; Pimozide; Potassium

1981
Partition of dopamine antagonists into synthetic lipid bilayers: the effect of membrane structure and composition.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:7

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Dimyristoylphosphatidylcholine; Domperidone; Dopamine Antagonists; Fluspirilene; Haloperidol; Lipid Bilayers; Phosphatidylcholines; Pimozide

1993
Characterization of inhibition by haloperidol and chlorpromazine of a voltage-activated K+ current in rat phaeochromocytoma cells.
    British journal of pharmacology, 1995, Volume: 116, Issue:6

    Topics: Animals; Antipsychotic Agents; Barium; Calcium Channels; Calmodulin; Chlorpromazine; Dopamine D2 Receptor Antagonists; Fluspirilene; GTP-Binding Proteins; Haloperidol; Ion Channel Gating; Membrane Potentials; PC12 Cells; Pimozide; Potassium; Potassium Channels; Rats

1995
Stable expression and characterization of the human brain potassium channel Kv2.1: blockade by antipsychotic agents.
    Brain research, 1997, Jun-27, Volume: 761, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain Chemistry; Cloning, Molecular; Female; Fluspirilene; Gene Expression; Glioblastoma; Humans; Ion Channel Gating; Molecular Sequence Data; Myocardium; Oocytes; Patch-Clamp Techniques; Pimozide; Polymerase Chain Reaction; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Trifluoperazine; Trifluperidol; Tumor Cells, Cultured; Xenopus

1997
A crystallographic and molecular modeling study of butyrophenones.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:12

    Topics: Butyrophenones; Crystallography; Fluspirilene; Models, Molecular; Molecular Structure; Pimozide; Spiperone

1998
[Blockade of HERG K+ channels expressed in Xenopus oocytes by antipsychotic agents].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2001, Volume: 47, Issue:1

    Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Female; Fluspirilene; Haloperidol; In Vitro Techniques; Oocytes; Pimozide; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Xenopus laevis

2001
Testosterone-mediated modulation of HERG blockade by proarrhythmic agents.
    Biochemical pharmacology, 2001, Jul-01, Volume: 62, Issue:1

    Topics: Androgens; Animals; Antipsychotic Agents; Cation Transport Proteins; DNA-Binding Proteins; Drug Interactions; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluspirilene; Haloperidol; Humans; Oocytes; Pimozide; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Testosterone; Trans-Activators; Transcriptional Regulator ERG; Transfection; Xenopus laevis

2001
Induction of abscisic acid-regulated gene expression by diacylglycerol pyrophosphate involves Ca2+ and anion currents in Arabidopsis suspension cells.
    Plant physiology, 2006, Volume: 141, Issue:4

    Topics: Abscisic Acid; Anions; Arabidopsis; Arabidopsis Proteins; Calcium; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Chelating Agents; Diphosphates; Egtazic Acid; Fluspirilene; Gene Expression Regulation, Plant; Glycerol; Membrane Potentials; Pimozide; Signal Transduction

2006
Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion.
    American journal of physiology. Cell physiology, 2015, Jun-01, Volume: 308, Issue:11

    Topics: Action Potentials; Adrenocorticotropic Hormone; Angiotensin II; Animals; Benzamides; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cattle; Cyclic AMP; Dihydropyridines; Fluspirilene; Gene Expression; Hydrocortisone; Microelectrodes; Nifedipine; Patch-Clamp Techniques; Penfluridol; Pimozide; Piperidines; Protein Isoforms; Single-Cell Analysis; Zona Fasciculata

2015
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
    Diabetes, 2023, 01-01, Volume: 72, Issue:1

    Topics: Animals; Antipsychotic Agents; Coenzyme A-Transferases; Diabetes Mellitus, Type 2; Dopamine; Fluspirilene; Hyperglycemia; Mice; Mice, Obese; Penfluridol; Pimozide; Receptors, Dopamine

2023