Page last updated: 2024-08-22

pimozide and fluoxetine

pimozide has been researched along with fluoxetine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's8 (25.81)18.2507
2000's9 (29.03)29.6817
2010's11 (35.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Jia, L; Sun, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Sen, S; Sinha, N1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hollander, E; Stein, DJ1
Maickel, RP; Spratto, GR; Tocco, DR1
Snoddy, AM; Tessel, RE1
Delashaw, JB; Dement, WC; Foutz, AS; Guilleminault, C1
Friedman, EH1
Guthrie, S; Hansen-Grant, S; Silk, KR1
McElroy, SL; Phillips, KA1
Hollander, E; Josephson, SC; Stein, DJ1
Ahmed, I; Dagincourt, PG; Miller, LG; Shader, RI1
Arya, DK; Taylor, WS1
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M1
Kessler, AR1
Phillips, KA1
Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS1
Kenchaiah, BK; Kumar, S; Tharyan, P1
Calì, PV; Di Pino, A; Gulisano, M; Rizzo, R1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1

Reviews

2 review(s) available for pimozide and fluoxetine

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for pimozide and fluoxetine

ArticleYear
Low-dose pimozide augmentation of serotonin reuptake blockers in the treatment of trichotillomania.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:4

    Topics: Adult; Clomipramine; Comorbidity; Dopamine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Pimozide; Serotonin; Trichotillomania

1992
Placebo-controlled study of pimozide augmentation of fluoxetine in body dysmorphic disorder.
    The American journal of psychiatry, 2005, Volume: 162, Issue:2

    Topics: Adult; Antipsychotic Agents; Delusions; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Pimozide; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Somatoform Disorders; Treatment Outcome

2005

Other Studies

27 other study(ies) available for pimozide and fluoxetine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Differential analgetic actions of amphetamine enantiomers in the mouse: a drug-drug interaction study.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Dextroamphetamine; Dopamine; Drug Interactions; Fenclonine; Fluoxetine; Male; Metergoline; Mice; Morphine; Naloxone; Norepinephrine; Pimozide; Serotonin; Stereoisomerism

1985
Prazosin: effect on psychomotor-stimulant cues and locomotor activity in mice.
    European journal of pharmacology, 1985, Oct-22, Volume: 116, Issue:3

    Topics: Amphetamine; Animals; Cocaine; Cues; Discrimination, Psychological; Fluoxetine; Male; Mice; Mice, Inbred ICR; Motor Activity; Pimozide; Prazosin; Propranolol; Stereotyped Behavior

1985
Monoaminergic mechanisms and experimental cataplexy.
    Annals of neurology, 1981, Volume: 10, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Cataplexy; Dogs; Female; Fluoxetine; Haloperidol; Humans; Male; Methylphenidate; Monoamine Oxidase Inhibitors; Physostigmine; Pimozide; Propranolol; Sleep, REM; Sodium Oxybate

1981
Re: Bradycardia and somnolence after adding fluoxetine to pimozide regimen.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:10

    Topics: Aged; Bradycardia; Brain Stem; Cerebral Cortex; Dementia; Dominance, Cerebral; Drug Synergism; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Paranoid Disorders; Pimozide; Wakefulness

1994
Fluoxetine-pimozide interaction.
    The American journal of psychiatry, 1993, Volume: 150, Issue:11

    Topics: Adult; Delusions; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Pimozide; Receptors, Dopamine

1993
Insight, overvalued ideation, and delusional thinking in body dysmorphic disorder: theoretical and treatment implications.
    The Journal of nervous and mental disease, 1993, Volume: 181, Issue:11

    Topics: Adult; Awareness; Body Image; Clomipramine; Delusions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Models, Psychological; Pimozide; Selective Serotonin Reuptake Inhibitors

1993
Serotonin reuptake blockers for the treatment of obsessional jealousy.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:1

    Topics: 1-Naphthylamine; Adult; Clomipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Jealousy; Male; Obsessive-Compulsive Disorder; Pimozide; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline

1994
Possible interaction between fluoxetine and pimozide causing sinus bradycardia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:1

    Topics: Aged; Arrhythmia, Sinus; Bradycardia; Delusions; Dementia; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Paranoid Disorders; Pimozide

1993
Lactation associated with fluoxetine treatment.
    The Australian and New Zealand journal of psychiatry, 1995, Volume: 29, Issue:4

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Galactorrhea; Humans; Hyperprolactinemia; Pimozide; Psychotic Disorders

1995
Pharmacological profile of neuroleptics at human monoamine transporters.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium

1999
Effects of medications on regulation of body temperature of patients with Tourette syndrome.
    Journal of child neurology, 2004, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Body Temperature Regulation; Child; Child, Preschool; Circadian Rhythm; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Haloperidol; Humans; Hypothalamic Diseases; Male; Middle Aged; Neurologic Examination; Pimozide; Tourette Syndrome; Treatment Outcome

2004
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
    Neuroscience letters, 2006, Nov-13, Volume: 408, Issue:2

    Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Pimozide; Rats; Seizures; Status Epilepticus

2006
Atypical anti-psychotics in delusional parasitosis: a retrospective case series of 20 patients.
    International journal of dermatology, 2010, Volume: 49, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Ectoparasitic Infestations; Female; Fluoxetine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Olanzapine; Pimozide; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Sertraline

2010
Mandatory electrocardiographic monitoring in young patients treated with psychoactive drugs.
    European child & adolescent psychiatry, 2013, Volume: 22, Issue:9

    Topics: Antipsychotic Agents; Child; Electrocardiography; Fluoxetine; Humans; Long QT Syndrome; Male; Pimozide; Selective Serotonin Reuptake Inhibitors; Tourette Syndrome

2013
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016