Page last updated: 2024-08-22

pimozide and flunarizine

pimozide has been researched along with flunarizine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hays, S; Roufos, I; Schwarz, RD1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Back, SK; Choo, HY; Kam, YL; Na, HS; Rhee, HK; Rhim, H1
Baek, du J; Cho, YS; Choi, YH; Lee, JK; Min, SJ; Pae, AN; Seo, SH1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Bomberger, JM; Deschamps, JD; Flitter, BA; Freedman, CJ; Holman, TR; Jadhav, A; Jameson, JB; Maloney, DJ; Melvin, JA; Nguyen, JV; Ogunsola, AF; Simeonov, A; Yasgar, A1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Johnston, LR; Wigham, T1
Jouannet, P; Patrat, C; Serres, C1
Cayabyab, FS; Hamming, KS; McRory, JE; Mezeyova, J; Parker, D; Santi, CM; Snutch, TP; Stea, A; Sutton, KG1
Haynes, J; Li, M; Obiako, BO; Stevens, T; Stubbs, JR; Taylor, JT; Wu, S1

Reviews

1 review(s) available for pimozide and flunarizine

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016

Other Studies

12 other study(ies) available for pimozide and flunarizine

ArticleYear
A structure-activity relationship study of novel phenylacetamides which are sodium channel blockers.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Acetamides; Animals; Benzeneacetamides; CHO Cells; Cricetinae; Magnetic Resonance Spectroscopy; Molecular Structure; Piperidines; Sodium; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Veratridine

1996
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Analgesics; Animals; Calcium Channels, T-Type; Humans; Neuralgia; Pain Measurement; Piperazines; Rats

2010
Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Benzhydryl Compounds; Calcium Channel Blockers; Calcium Channels, T-Type; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; High-Throughput Screening Assays; Humans; Piperazines; Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.
    Biochemistry, 2016, 06-14, Volume: 55, Issue:23

    Topics: Amino Acid Sequence; Animals; Antibody Formation; Arachidonate 15-Lipoxygenase; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Lipoxygenase Inhibitors; Pseudomonas aeruginosa; Rabbits; Substrate Specificity

2016
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
The intracellular regulation of prolactin cell function in the rainbow trout, Salmo gairdneri.
    General and comparative endocrinology, 1988, Volume: 71, Issue:2

    Topics: Animals; Apomorphine; Bucladesine; Calcimycin; Calcium; Colforsin; Dopamine; Female; Flunarizine; Guanosine Triphosphate; In Vitro Techniques; Pimozide; Pituitary Gland; Prolactin; Salmonidae; Trout

1988
Induction of a sodium ion influx by progesterone in human spermatozoa.
    Biology of reproduction, 2000, Volume: 62, Issue:5

    Topics: Acrosome Reaction; Calcium; Calcium Channel Blockers; Extracellular Matrix; Flunarizine; Humans; Male; Pimozide; Progesterone; Sodium; Sodium Channel Blockers; Sperm Capacitation; Spermatozoa

2000
Differential inhibition of T-type calcium channels by neuroleptics.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jan-15, Volume: 22, Issue:2

    Topics: Antipsychotic Agents; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Line; Dose-Response Relationship, Drug; Flunarizine; Haloperidol; Humans; Ion Channel Gating; Kidney; Patch-Clamp Techniques; Penfluridol; Pimozide; Piperidines; Transfection

2002
Cav3.1 (alpha1G) T-type Ca2+ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation.
    Circulation research, 2003, Aug-22, Volume: 93, Issue:4

    Topics: Amino Acid Sequence; Anemia, Sickle Cell; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Erythrocytes, Abnormal; Flunarizine; Lung; Membrane Potentials; Mibefradil; Microcirculation; Molecular Sequence Data; Neurotoxins; Nickel; Pimozide; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Scorpion Venoms; Sequence Homology, Amino Acid

2003