Page last updated: 2024-08-22

pimozide and cocaine

pimozide has been researched along with cocaine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199022 (57.89)18.7374
1990's6 (15.79)18.2507
2000's7 (18.42)29.6817
2010's3 (7.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Colpaert, FC; Janssen, PA; Niemegeers, CJ2
Hope, W; McCulloch, MW; Rand, MJ; Story, DF1
Englert, LF; Ho, BT; Mckenna, ML1
De Wit, H; Wise, RA1
Holbrook, JM; Wilson, MC1
Cuparencu, B; Sandor, V1
Niemegeers, CJ; Wauquier, A1
Julesz, J; Sarnyai, Z; Szabó, G; Telegdy, G; Vecsernyés, M1
Kamien, JB; Woolverton, WL1
Virus, RM; Woolverton, WL1
Gerber, GJ; Wise, RA1
Woolverton, WL1
Amit, Z; Hunt, T; Switzman, L1
Beninger, RJ; Morency, MA1
Cone, EJ; Risner, ME1
Snoddy, AM; Tessel, RE1
Beninger, RJ; Herz, RS1
Angrist, B; Gershon, S1
Jones, BE; Risner, ME1
Fibiger, HC; Phillips, AG; Spyraki, C1
Catravas, JD; Waters, IW1
Hikasa, N; Otsuki, S; Sato, M; Tomoda, T1
Bíró, E; Sarnyai, Z; Telegdy, G1
Chang, JY; Lee, RS; Sawyer, SF; Woodward, DJ1
Justice, JB; Parsons, LH; Schad, CA1
Glowa, JR; Wojnicki, FH1
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M1

Reviews

1 review(s) available for pimozide and cocaine

ArticleYear
Dopamine and psychotic states: preliminary remarks.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carbon Radioisotopes; Cats; Cocaine; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Methylphenidate; Pemoline; Phenmetrazine; Pimozide; Psychoses, Substance-Induced; Psychotic Disorders; Rats; Receptors, Cell Surface; Species Specificity; Stereotyped Behavior; Thioridazine; Tyrosine

1974

Other Studies

37 other study(ies) available for pimozide and cocaine

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Neuroleptic interference with the cocaine cue: internal stimulus control of behavior and psychosis.
    Psychopharmacology, 1978, Jul-19, Volume: 58, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior; Cocaine; Cues; Drug Interactions; Haloperidol; Humans; Male; Pimozide; Psychotic Disorders; Rats; Spiperone

1978
Effects of pimozide on noradrenergic transmission in rabbit isolated ear arteries.
    European journal of pharmacology, 1977, Nov-15, Volume: 46, Issue:2

    Topics: Animals; Anura; Arteries; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Heart Atria; Histamine; In Vitro Techniques; Norepinephrine; Pimozide; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Vasoconstrictor Agents

1977
Generalization of norcocaine to the discriminative stimulus properties of cocaine.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:2

    Topics: Animals; Cocaine; Dealkylation; Discrimination Learning; Discrimination, Psychological; Generalization, Psychological; Male; Pimozide; Rats; Reinforcement Schedule; Reserpine

1979
Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.
    Canadian journal of psychology, 1977, Volume: 31, Issue:4

    Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Male; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reinforcement, Psychology

1977
Intravenous cocaine lethality in the rat.
    Pharmacological research communications, 1978, Volume: 10, Issue:3

    Topics: Animals; Brain Chemistry; Catecholamines; Cocaine; Drug Interactions; Exploratory Behavior; Infusions, Parenteral; Male; Methyltyrosines; Pimozide; Rats; Seizures; Thiourea; Time Factors

1978
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol

1977
Restoration of self-stimulation inhibited by neuroleptics.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Cocaine; Dexetimide; Dopamine Antagonists; Isoquinolines; Male; Pimozide; Rats; Receptors, Dopamine; Self Stimulation; Tranquilizing Agents

1976
Cocaine cue in rats as it relates to subjective drug effects: a preliminary report.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Cocaine; Conditioning, Operant; Cues; Cyproheptadine; Dibenzylchlorethamine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Haloperidol; Methysergide; Pimozide; Propranolol; Rats

1976
Effects of cocaine and pimozide on plasma and brain alpha-melanocyte-stimulating hormone levels in rats.
    Neuroendocrinology, 1992, Volume: 55, Issue:1

    Topics: alpha-MSH; Animals; Brain; Cocaine; Male; Pimozide; Pituitary Gland; Rats; Rats, Inbred Strains

1992
A pharmacological analysis of the discriminative stimulus properties of d-amphetamine in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Animals; Apomorphine; Benzazepines; Cocaine; Dextroamphetamine; Discrimination Learning; Macaca mulatta; Male; Phentolamine; Pimozide; Prazosin; Receptors, Dopamine

1989
The effects of a D1 and a D2 dopamine antagonist on behavior maintained by cocaine or food.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:3

    Topics: Animals; Benzazepines; Cocaine; Dose-Response Relationship, Drug; Feeding Behavior; Female; Macaca mulatta; Male; Pimozide; Receptors, Dopamine; Reinforcement, Psychology; Self Administration

1989
Pharmacological regulation of intravenous cocaine and heroin self-administration in rats: a variable dose paradigm.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:2

    Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Injections, Intravenous; Male; Pimozide; Rats; Rats, Inbred Strains; Self Administration

1989
Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzazepines; Cocaine; Drug Interactions; Female; Macaca mulatta; Male; Pimozide; Piperazines; Piribedil; Receptors, Dopamine; Self Administration

1986
Involvement of dopamine in the aversive stimulus properties of cocaine in rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:6

    Topics: Animals; Chlorides; Cocaine; Conditioning, Operant; Dopamine; Drinking; Drug Interactions; Lithium; Lithium Chloride; Male; Pimozide; Rats; Rats, Inbred Strains; Reinforcement, Psychology

1985
Dopaminergic substrates of cocaine-induced place conditioning.
    Brain research, 1986, Dec-03, Volume: 399, Issue:1

    Topics: Animals; Brain; Cocaine; Conditioning, Classical; Cues; Dopamine; Environment; Injections, Intraventricular; Male; Pimozide; Rats; Rats, Inbred Strains; Synaptic Transmission

1986
Intravenous self-administration of fencamfamine and cocaine by beagle dogs under fixed-ratio and progressive-ratio schedules of reinforcement.
    Drug and alcohol dependence, 1986, Volume: 17, Issue:1

    Topics: Animals; Cocaine; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Male; Norbornanes; Pimozide; Reinforcement Schedule; Self Administration

1986
Prazosin: effect on psychomotor-stimulant cues and locomotor activity in mice.
    European journal of pharmacology, 1985, Oct-22, Volume: 116, Issue:3

    Topics: Amphetamine; Animals; Cocaine; Cues; Discrimination, Psychological; Fluoxetine; Male; Mice; Mice, Inbred ICR; Motor Activity; Pimozide; Prazosin; Propranolol; Stereotyped Behavior

1985
Pimozide blocks establishment but not expression of cocaine-produced environment-specific conditioning.
    Life sciences, 1986, Apr-14, Volume: 38, Issue:15

    Topics: Animals; Cocaine; Conditioning, Psychological; Male; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine

1986
Intravenous self-administration of cocaine and norcocaine by dogs.
    Psychopharmacology, 1980, Volume: 71, Issue:1

    Topics: Animals; Cocaine; Dextroamphetamine; Dogs; Infusions, Parenteral; Phenoxybenzamine; Pimozide; Self Administration; Time Factors

1980
Cocaine-induced place preference conditioning: lack of effects of neuroleptics and 6-hydroxydopamine lesions.
    Brain research, 1982, Dec-16, Volume: 253, Issue:1-2

    Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Orientation; Oxidopamine; Pimozide; Procaine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reinforcement Schedule

1982
Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2

    Topics: Animals; Blood; Body Temperature; Chlorpromazine; Cocaine; Cold Temperature; Diazepam; Dogs; Female; Hemodynamics; Hydrogen-Ion Concentration; Male; Pancuronium; Pimozide; Propranolol

1981
Inhibition of amygdaloid kindling by chronic pretreatment with cocaine or methamphetamine.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Amygdala; Animals; Apomorphine; Cats; Cocaine; Electric Stimulation; Evoked Potentials; Haloperidol; Methamphetamine; Pimozide; Receptors, Dopamine; Seizures

1980
Cocaine-induced elevation of plasma corticosterone is mediated by different neurotransmitter systems in rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: Animals; Atropine; Cocaine; Corticosterone; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Neurotransmitter Agents; Phenoxybenzamine; Pimozide; Propranolol; Rats; Rats, Wistar

1993
Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:3 Pt 1

    Topics: Action Potentials; Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine D2 Receptor Antagonists; Male; Movement; Neurons; Nucleus Accumbens; Pimozide; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement, Psychology; Self Administration

1994
Co-administration of the D2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine.
    Journal of neurochemistry, 1993, Volume: 60, Issue:1

    Topics: Analysis of Variance; Animals; Cocaine; Dialysis; Dopamine; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Male; Nucleus Accumbens; Pimozide; Rats; Rats, Wistar; Up-Regulation

1993
Effects of drugs on food- and cocaine-maintained responding, III: Dopaminergic antagonists.
    Psychopharmacology, 1996, Volume: 128, Issue:4

    Topics: Animals; Benzazepines; Chlorpromazine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Food; Macaca mulatta; Male; Narcotics; Pimozide; Self Administration

1996
Pharmacological profile of neuroleptics at human monoamine transporters.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium

1999