pimobendan has been researched along with ud cg 212 cl in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endoh, M; Ishihata, A; Norota, I; Satoh, H; Shibasaki, T | 1 |
| Ovaska, M; Taskinen, J | 1 |
| Meyer, W; Scholz, H | 1 |
| Brand, HJ; Hagemeijer, F; Roth, W | 2 |
| Brunkhorst, D; Meyer, W; Nigbur, R; Schmidt-Schumacher, C; Scholz, H; v der Leyen, H | 1 |
| Belch, JJ; Forbes, CD; Lowe, GD; Saniabadi, AR | 1 |
| Duncker, DJ; Levinsky, L; Rutteman, AM; Saxena, PR; Verdouw, PD | 1 |
| Bernard, R; Dresse, A; Goethals, H; Liebens, I; Renard, M; Walter, M | 1 |
| Duncker, DJ; Hartog, JM; Levinsky, L; Verdouw, PD | 1 |
| Entzeroth, M; Haigh, RM; Redemann, N; van Meel, JC | 1 |
| Fujimoto, S | 1 |
| Brogden, RN; Fitton, A | 1 |
| Komukai, K; Kurihara, S | 1 |
| Fraker, LD; Solaro, RJ; Van Eyk, J | 1 |
| Chen, CH; Kubo, M; Minami, K; Nakaya, Y | 1 |
| Endoh, M; Takahashi, R | 1 |
| Endoh, M; Shimazaki, Y; Takahashi, R | 1 |
| Kasanuki, H; Matsuda, N; Naganuma, M; Shiga, T; Tatami, S; Wakaumi, M | 1 |
1 review(s) available for pimobendan and ud cg 212 cl
| Article | Year |
|---|---|
Pimobendan. A review of its pharmacology and therapeutic potential in congestive heart failure.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Clinical Trials as Topic; Drug Interactions; Electrophysiology; Heart Failure; Hemodynamics; Humans; Intestinal Absorption; Liver; Myocardium; Phosphodiesterase Inhibitors; Pyridazines | 1994 |
2 trial(s) available for pimobendan and ud cg 212 cl
| Article | Year |
|---|---|
Pimobendane (UD-CG 115 BS) in the treatment of severe congestive heart failure. An acute haemodynamic cross-over and double-blind study with two different doses.
Topics: Aged; Cardiac Output; Cardiotonic Agents; Clinical Trials as Topic; Double-Blind Method; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Pulmonary Circulation; Pyridazines; Random Allocation; Vascular Resistance | 1988 |
Plasma concentration profile of orally administered pimobendan and plasma brain natriuretic peptide level in patients with severe heart failure.
Topics: Administration, Oral; Cardiomyopathy, Dilated; Cardiotonic Agents; Heart Failure; Humans; Natriuretic Peptide, Brain; Pyridazines | 2003 |
16 other study(ies) available for pimobendan and ud cg 212 cl
| Article | Year |
|---|---|
Different mechanisms involved in the positive inotropic effects of benzimidazole derivative UD-CG 115 BS (pimobendan) and its demethylated metabolite UD-CG 212 Cl in canine ventricular myocardium.
Topics: Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Propanolamines; Pyridazines; Vasodilator Agents | 1991 |
A model for human cardiac troponin C and for modulation of its Ca2+ affinity by drugs.
Topics: Amino Acid Sequence; Asparagine; Bepridil; Binding Sites; Calcium; Calmodulin; Glycine; Humans; Models, Molecular; Molecular Sequence Data; Myocardium; Protein Conformation; Pyridazines; Trifluoperazine; Troponin; Troponin C; Vasodilator Agents | 1991 |
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Cardiovascular effects and plasma level profile of pimobendan (UD-CG 115 BS) and its metabolite UD-CG 212 in patients with congestive heart failure after single and repeated oral dosing.
Topics: Aged; Blood Chemical Analysis; Blood Pressure; Cardiac Output; Cardiotonic Agents; Exercise Test; Female; Glucose Tolerance Test; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Pyridazines; Time Factors | 1989 |
Correlations between the cardiovascular effects of pimobendan and plasma concentrations of the parent compound and of its major active metabolite, UD-CG 212 CL, in patients with congestive heart failure.
Topics: Administration, Oral; Aged; Cardiotonic Agents; Cardiovascular System; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Pyridazines; Time Factors | 1989 |
Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart.
Topics: Animals; Cardiotonic Agents; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoenzymes; Milrinone; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyridones | 1989 |
Platelet aggregation inhibitory effects of the new positive inotropic agents pimobendan and UD CG 212 in whole blood.
Topics: Adult; Blood Platelets; Cardiotonic Agents; Dipyridamole; Drug Synergism; Female; Humans; Male; Microscopy, Electron; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridazines | 1989 |
Cardiovascular effects of UD-CG 212 CL, a metabolite of pimobendan, in anaesthetized pigs.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Cardiotonic Agents; Coronary Circulation; Hemodynamics; Oxygen Consumption; Pyridazines; Regional Blood Flow; Swine | 1987 |
Systemic haemodynamic actions of pimobendan (UD-CG 115 BS) and its O-demethylmetabolite UD-CG 212 Cl in the conscious pig.
Topics: Animals; Cardiotonic Agents; Hemodynamics; Infusions, Intravenous; Propranolol; Pyridazines; Swine | 1987 |
Effects of pimobendan and its metabolite on myofibrillar calcium responsiveness and ATPase activity in the presence of inorganic phosphate.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cardiotonic Agents; Dogs; Heart Ventricles; In Vitro Techniques; Kinetics; Muscle Fibers, Skeletal; Myocardial Contraction; Myofibrils; Phosphates; Pyridazines | 1995 |
Effects of pimobendan, its active metabolite UD-CG 212, and milrinone on isolated blood vessels.
Topics: Animals; Cardiotonic Agents; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Milrinone; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Rats; Rats, Wistar; Vasodilator Agents | 1994 |
Mechanisms of the inotropic effects of UD-CG 212 Cl, an active metabolite of pimobendan, on ferret papillary muscles.
Topics: Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Ferrets; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines | 1996 |
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle.
Topics: Actin Cytoskeleton; Calcium; Cardiotonic Agents; Heart; Heart Ventricles; Humans; Myocardial Contraction; Phosphates; Pyridazines | 1997 |
Effects of pimobendan and its active metabolite, UD-CG 212 Cl, on Ca2+-activated K+ channels in vascular smooth-muscle cells.
Topics: Animals; Calcium; Cardiotonic Agents; Coronary Vessels; Drug Interactions; Enzyme Inhibitors; Heart; Isoquinolines; Muscle, Smooth, Vascular; Potassium Channels; Pyridazines; Sulfonamides; Swine; Vasodilation | 1997 |
Increase in myofibrillar Ca2+ sensitivity induced by UD-CG 212 Cl, an active metabolite of pimobendan, in canine ventricular myocardium.
Topics: Animals; Calcium; Carbachol; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Female; Male; Myocardial Contraction; Myofibrils; Pyridazines; Signal Transduction | 2001 |
Decrease in Ca(2+)-sensitizing effect of UD-CG 212 Cl, a metabolite of pimobendan, under acidotic condition in canine ventricular myocardium.
Topics: Acidosis; Actin Cytoskeleton; Aequorin; Animals; Calcium; Cardiotonic Agents; Dogs; Female; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Pyridazines | 2001 |