pimagedine has been researched along with pyruvaldehyde in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (14.89) | 18.2507 |
| 2000's | 18 (38.30) | 29.6817 |
| 2010's | 16 (34.04) | 24.3611 |
| 2020's | 6 (12.77) | 2.80 |
| Authors | Studies |
|---|---|
| Lo, TW; Selwood, T; Thornalley, PJ | 1 |
| Selwood, T; Thornalley, PJ | 1 |
| Asahi, M; Che, W; Higashiyama, S; Kaneto, H; Okado, A; Takahashi, M; Taniguchi, N | 1 |
| Glomb, MA; Nagaraj, RH; Shipanova, IN | 1 |
| Al-Abed, Y; Bucala, R; Ferguson, GP; VanPatten, S | 1 |
| Abordo, EA; Minhas, HS; Thornalley, PJ | 1 |
| Lagarde, M; Lecomte, M; Moinet, G; Patereau, G; Ruggiero-Lopez, D; Wiernsperger, N | 1 |
| Kikuchi, S; Moriwaka, F; Ogata, A; Sasaki, H; Shinpo, K; Tashiro, K | 1 |
| Argirov, OK; Thornalley, PJ; Yurek-George, A | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Kinoshita, T; Nohara, Y; Usui, T; Watanabe, M | 1 |
| Cervantes-Laurean, D; Jacobson, EL; Jacobson, MK; Kim, M; Qasem, JG; Roberts, MJ; Wondrak, GT | 1 |
| Bellmunt, MJ; Nègre-Salvayre, A; Pamplona, R; Portero-Otín, M; Prat, J; Ruiz, MC; Salvayre, R | 1 |
| Inagi, R; Kurokawa, K; Miyata, T; Nangaku, M; Ueda, Y; van Ypersele de Strihou, C; Yoshino, A | 1 |
| Gugliucci, A; Menini, T | 1 |
| Alpar, A; Arendt, T; Berbaum, K; de Arriba, SG; Gärtner, U; Loske, C; Münch, G; Urban, C; Webster, J | 1 |
| Brownlee, M; Kern, TS; Kinter, MT; Monnier, VM; Mustata, TG; Ozdemir, AM; Rosca, MG; Szweda, LI; Weiss, MF | 1 |
| Hirano, K; Kato, M; Kiho, T; Usui, S | 1 |
| Gerrard, JA; Miller, AG | 1 |
| Burnell, J; de Arriba, SG; Loske, C; Münch, G; Stuchbury, G; Yarin, J | 1 |
| Auge, N; Ayala, V; Cantero, AV; Elbaz, M; Nègre-Salvayre, A; Pamplona, R; Portero-Otín, M; Salvayre, R; Sanson, M; Thiers, JC | 1 |
| Chang, T; Desai, K; Jiang, B; Wang, X; Wu, L | 1 |
| Hamada, Y; Hazaka, Y; Ichijo, H; Kani, S; Minami, Y; Nakayama, E; Onishi, N; Sougawa, N; Takeda, K; Umeda, T; Yoda, A | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Chen, B; Chen, F; Cheng, KW; Ma, J; Peng, X; Wang, M | 1 |
| Desai, KM; Dhar, A; Dhar, I; Wu, L | 1 |
| Arnold, F; Bouzoud, D; Gasser, P; Lati, E; Luu, MT; Mercier, M; Peno-Mazzarino, L | 1 |
| Cheng, XS; Du, LL; Jiang, X; Li, XH; Lv, BL; Wang, JZ; Xie, JZ; Zhang, JY; Zhou, XW | 1 |
| Sparrow, JR; Ueda, K; Yamamoto, K; Yoon, KD; Zhou, J | 1 |
| Hara, Y; Mukohda, M; Okada, M; Yamawaki, H | 1 |
| Bernauer, R; Bierhaus, A; Brownlee, M; Fleming, TH; Herzig, S; Karimi, J; Kroll, J; Masania, J; Nawroth, PP; Nawrotzki, R; Rabbani, N; Theilen, TM; Thornalley, PJ; Tyedmers, J; Vittas, S; Wunderle, M | 1 |
| Chen, Z; Dai, H; He, P; Hu, Q; Li, W; Ren, X; Xu, H | 1 |
| Hernández-Laguna, A; Muñoz, F; Ortega-Castro, J; Solís-Calero, C | 1 |
| Abbasi, S; Bano, B; Choudhary, MI; Hussain, S; Khan, JA; Khan, KM; Perveen, S; Rasheed, S | 1 |
| Bocsik, A; Couraud, PO; Deli, MA; Dohgu, S; Kataoka, Y; Nagy, L; Puskás, LG; Sántha, P; Takata, F; Tóth, AE; Veszelka, S; Walter, FR | 1 |
| Kikuchi, H; Komuro, I; Morita, T; Nakajima, T; Nakamura, F; Oguri, G; Takano, N; Tanaka, T; Yamamoto, Y; Yamasoba, T | 1 |
| Deng, Y; Lin, F; Peng, L; Qing, H; Ullah, K; Wu, H; Xie, B | 1 |
| Deli, MA; Dohgu, S; Heimesaat, MM; Kataoka, Y; Kiss, L; Ózsvári, B; Puskás, LG; Rákhely, G; Tóth, A; Tóth, AE; Veszelka, S; Walter, FR | 1 |
| Dobes, P; Havlikova, M; Ulrichova, J; Vacek, J; Zatloukalova, M | 1 |
| Aldini, G; Carini, M; Casali, G; Colzani, M; De Maddis, D; Vistoli, G | 1 |
| Dain, JA; Frost, L; Kirschenbaum, LJ; Liu, W; Ma, H; Seeram, NP | 1 |
| Kim, SY; Lee, JH; Subedi, L | 1 |
| Do, MH; Kang, MC; Kim, SY; Lee, JH; Parveen, A; Yumnam, S | 1 |
| Collins, KD; Nallar, S; Prantner, D; Richard, K; Spiegel, D; Vogel, SN | 1 |
| Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U | 1 |
| Inoue, Y; Iwai, M; Kadoyama, K; Matsumoto, K; Nitta, Y; Takano-Ohmuro, H; Takasugi, R; Takenokuchi, M; Taniguchi, T; Yoshida, K | 1 |
| Raghu, KG; Sruthi, CR | 1 |
47 other study(ies) available for pimagedine and pyruvaldehyde
| Article | Year |
|---|---|
The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins.
Topics: Blood Proteins; Guanidines; Humans; Kinetics; Protein Binding; Pyruvaldehyde | 1994 |
Binding of methylglyoxal to albumin and formation of fluorescent adducts. Inhibition by arginine, N-alpha-acetylarginine and aminoguanidine.
Topics: Animals; Arginine; Cattle; Fluorescence; Guanidines; Humans; Protein Binding; Pyruvaldehyde; Rats; Serum Albumin, Bovine | 1993 |
Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arteriosclerosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyglucose; Diabetic Angiopathies; Epidermal Growth Factor; Gene Expression; Guanidines; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Peroxides; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic | 1997 |
Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct.
Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Glyceraldehyde; Guanidines; Kinetics; Maillard Reaction; Molecular Structure; Monosaccharides; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Spectrometry, Fluorescence; Spectrophotometry | 1997 |
Detoxification of methylglyoxal by the nucleophilic bidentate, phenylacylthiazolium bromide.
Topics: Antiporters; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Glutathione; Guanidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Potassium Channels; Potassium-Hydrogen Antiporters; Pyruvaldehyde; Thiazoles | 1999 |
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidines; Hydrogen Peroxide; Macrophages; Mice; Necrosis; Nitroarginine; Oxidative Stress; Pyruvaldehyde | 1999 |
Reaction of metformin with dicarbonyl compounds. Possible implication in the inhibition of advanced glycation end product formation.
Topics: Animals; Azepines; Cattle; Enzyme Inhibitors; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Hypoglycemic Agents; Metformin; Pyruvaldehyde; Serum Albumin | 1999 |
Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Glutathione; Glycation End Products, Advanced; Guanidines; Motor Neurons; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Spinal Cord | 2000 |
Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.
Topics: Deoxyglucose; Enzyme Inhibitors; Glyoxal; Guanidines; Kinetics; Pyruvaldehyde; Spectrophotometry; Triazines | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Generation of superoxide anions during the reaction of guanidino compounds with methylglyoxal.
Topics: Guanidine; Guanidines; Humans; Kidney Failure, Chronic; Oxidative Stress; Pyruvaldehyde; Superoxides | 2002 |
Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress.
Topics: Cells, Cultured; Chelating Agents; Enzyme Inhibitors; Free Radical Scavengers; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Kinetics; Penicillamine; Pyruvaldehyde | 2002 |
Advanced glycation end product precursors impair epidermal growth factor receptor signaling.
Topics: Cell Line, Transformed; Enzyme Inhibitors; ErbB Receptors; Fibroblasts; Glycation End Products, Advanced; Glyoxal; Guanidines; Humans; Hyperglycemia; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyruvaldehyde; Signal Transduction; Tyrosine | 2002 |
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Guanidines; Humans; In Vitro Techniques; Kidney Failure, Chronic; Lactoylglutathione Lyase; Membranes, Artificial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde; Yeasts | 2002 |
The botanical extracts of Achyrocline satureoides and Ilex paraguariensis prevent methylglyoxal-induced inhibition of plasminogen and antithrombin III.
Topics: Achyrocline; Antioxidants; Antithrombin III; Ascorbic Acid; Carnosine; Dose-Response Relationship, Drug; Guanidines; Ilex paraguariensis; Kinetics; Models, Biological; Plant Extracts; Plasminogen; Pyruvaldehyde | 2002 |
The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; Guanidines; Humans; Neuroprotective Agents; Piperazines; Pyruvaldehyde; Thiophenes | 2005 |
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation.
Topics: 2,4-Dinitrophenol; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electrophoresis, Gel, Two-Dimensional; Energy Metabolism; Fatty Acids; Glucose; Guanidines; Male; Mitochondria; Mitochondrial Proteins; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidants; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Pyruvaldehyde; Rats; Rats, Inbred Lew; Superoxides; Uncoupling Agents | 2005 |
Effect of buformin and metformin on formation of advanced glycation end products by methylglyoxal.
Topics: Animals; Buformin; Cattle; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Guanidines; Metformin; Pyruvaldehyde; Ribonucleases; Serum Albumin, Bovine; Time Factors | 2005 |
Assessment of protein function following cross-linking by alpha-dicarbonyls.
Topics: Amidines; Animals; Cattle; Cross-Linking Reagents; Dimyristoylphosphatidylcholine; Enzyme Inhibitors; Guanidines; Kinetics; Maillard Reaction; Proteins; Pyruvaldehyde; Ribonuclease, Pancreatic | 2005 |
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
Topics: Adenosine Triphosphate; Analysis of Variance; Cell Line, Tumor; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Flow Cytometry; Glucose; Guanidines; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Neurons; Piperazines; Pyruvaldehyde; Reactive Oxygen Species; Thiophenes | 2007 |
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Becaplermin; Cell Movement; Cell Proliferation; Cells, Cultured; Diabetes Complications; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glyoxal; Guanidines; Humans; Mesoderm; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyruvaldehyde; Rabbits; Receptor, Platelet-Derived Growth Factor beta | 2007 |
Attenuation of hypertension development by aminoguanidine in spontaneously hypertensive rats: role of methylglyoxal.
Topics: Animals; Aorta; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Free Radicals; Glutathione; Glycation End Products, Advanced; Guanidines; Hypertension; Male; Mesenteric Arteries; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2007 |
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line; Checkpoint Kinase 1; Checkpoint Kinase 2; Deoxyguanosine; Diabetes Mellitus; Enzyme Activation; G2 Phase; Guanidines; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase Kinase 5; Mesangial Cells; Mitosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvaldehyde; RNA, Small Interfering; Signal Transduction | 2007 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
High-performance liquid chromatographic determination of creatine kinase activity influenced by methylglyoxal.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Creatine Kinase; Data Interpretation, Statistical; Guanidines; Muscles; Pyruvaldehyde; Rabbits | 2009 |
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose.
Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Cells, Cultured; Cyclic GMP; Endothelial Cells; Glucose; Guanidines; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Diseases; Vasodilation | 2010 |
Glycation induction and antiglycation activity of skin care ingredients on living human skin explants.
Topics: Adult; Cosmetics; Female; Glucose; Guanidines; Humans; In Vitro Techniques; Pyruvaldehyde; Skin | 2011 |
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Enzyme Activation; Glycation End Products, Advanced; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanidines; Mice; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; tau Proteins; Up-Regulation | 2012 |
A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration.
Topics: Cells, Cultured; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glyoxal; Guanidines; Humans; Lipofuscin; Macular Degeneration; Phenylhydrazines; Pyridinium Compounds; Pyruvaldehyde; Retina; Retinal Drusen; Retinaldehyde; Retinoids; Spectrometry, Mass, Electrospray Ionization | 2012 |
Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Endothelium, Vascular; Glycation End Products, Advanced; Guanidines; Hypertension; In Vitro Techniques; Mesenteric Arteries; Nitroprusside; Pyruvaldehyde; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vasoconstriction; Vasodilation | 2012 |
Aging-dependent reduction in glyoxalase 1 delays wound healing.
Topics: Aging; Animals; Cells, Cultured; Down-Regulation; Fibroblasts; Guanidines; Lactoylglutathione Lyase; Male; Mice; Mice, Inbred C57BL; Pyruvaldehyde; Wound Healing | 2013 |
[Aminoguanidine suppresses methylglyoxal-mediated oxygen-glucose deprivation injury in human brain microvascular endothelial cells].
Topics: Apoptosis; Cell Hypoxia; Cell Survival; Cells, Cultured; Drug Antagonism; Endothelial Cells; Endothelium, Vascular; Glycation End Products, Advanced; Guanidines; Humans; Pyruvaldehyde | 2013 |
DFT study of the mechanism of the reaction of aminoguanidine with methylglyoxal.
Topics: Guanidines; Hydrogen Bonding; Models, Chemical; Models, Molecular; Pyruvaldehyde; Thermodynamics | 2014 |
Antiglycation activity of quinoline derivatives- a new therapeutic class for the management of type 2 diabetes complications.
Topics: Animals; Antioxidants; Biphenyl Compounds; Cattle; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glycosylation; Guanidines; Hypoglycemic Agents; Mice; NIH 3T3 Cells; Picrates; Pyruvaldehyde; Quinolines; Reactive Oxygen Species; Rutin; Schiff Bases; Serum Albumin, Bovine; Structure-Activity Relationship | 2014 |
Edaravone protects against methylglyoxal-induced barrier damage in human brain endothelial cells.
Topics: Antipyrine; beta Catenin; Blood-Brain Barrier; Cell Line; Cell Survival; Claudin-5; Edaravone; Electric Impedance; Endothelial Cells; Endothelium, Vascular; Free Radical Scavengers; Guanidines; Humans; Oxidative Stress; Permeability; Protective Agents; Pyruvaldehyde; Reactive Oxygen Species; Tight Junctions | 2014 |
Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.
Topics: Acetanilides; Allyl Compounds; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Cycle; Cell Line; Fibroblasts; Guanidines; Heart Ventricles; Humans; Isocyanates; Nerve Tissue Proteins; Purines; Pyruvaldehyde; RNA, Messenger; Ruthenium Red; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2014 |
Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells.
Topics: Cell Line; Diabetes Mellitus, Type 2; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Gene Expression; Guanidines; Humans; Isoquinolines; Membrane Potential, Mitochondrial; Models, Neurological; Neurotoxins; Oxidative Stress; Parkinson Disease; Pyruvaldehyde; RNA, Messenger; Tyrosine 3-Monooxygenase | 2014 |
Compounds blocking methylglyoxal-induced protein modification and brain endothelial injury.
Topics: Alzheimer Disease; Antioxidants; beta Catenin; Blood-Brain Barrier; Butadienes; Cell Line; Cell Survival; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Guanidines; Humans; MAP Kinase Signaling System; Nitriles; Pyruvaldehyde; Reactive Oxygen Species; Signal Transduction; Tight Junction Proteins; Tretinoin | 2014 |
Electrocatalytic assay for monitoring methylglyoxal-mediated protein glycation.
Topics: Amino Acid Sequence; Animals; Biological Assay; Catalysis; Cattle; Electrochemistry; Electrodes; Enzyme Inhibitors; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Models, Molecular; Molecular Sequence Data; Muramidase; Protein Conformation; Pyruvaldehyde; Serum Albumin; Serum Albumin, Bovine | 2015 |
Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study.
Topics: Aldehydes; Carnosine; Dose-Response Relationship, Drug; Glyoxal; Guanidines; Humans; Hydralazine; Malondialdehyde; Molecular Structure; Pyridoxamine; Pyruvaldehyde; Sequestering Agents; Structure-Activity Relationship | 2016 |
Glucitol-core containing gallotannins inhibit the formation of advanced glycation end-products mediated by their antioxidant potential.
Topics: Acer; Antioxidants; Circular Dichroism; Deoxyglucose; Digoxin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Fructose; Gallic Acid; Glucosidases; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Glycosylation; Guanidines; Hydrolyzable Tannins; Hypoglycemic Agents; Inhibitory Concentration 50; Iron; Iron Chelating Agents; Plant Extracts; Polyphenols; Protein Structure, Secondary; Pyruvaldehyde; Serum Albumin, Bovine; Sorbitol | 2016 |
Effect of Cysteine on Methylglyoxal-Induced Renal Damage in Mesangial Cells.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Cysteine; Guanidines; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lactoylglutathione Lyase; MAP Kinase Signaling System; Mesangial Cells; Mice; Pyruvaldehyde; Reactive Oxygen Species; Sirtuin 1 | 2020 |
Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells.
Topics: Aorta; Apoptosis; Autophagosomes; Autophagy; bcl-2-Associated X Protein; Caspase 3; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Endothelial Cells; Guanidines; Humans; MAP Kinase Signaling System; Microtubule-Associated Proteins; Models, Biological; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyruvaldehyde; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Vacuoles | 2020 |
Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response.
Topics: Aerobiosis; Animals; Cell Death; Cell Polarity; Cells, Cultured; Female; Glycolysis; Guanidines; Inflammation; Interferon-gamma; Lactoylglutathione Lyase; Lung; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Phenotype; Pyruvaldehyde; Receptor for Advanced Glycation End Products; RNA, Messenger; Serum Albumin, Bovine; Toll-Like Receptor 4; Up-Regulation | 2021 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |
In Vitro and In Vivo Antiglycation Effects of Connarus ruber Extract.
Topics: Animals; Arginine; Collagen; Connaraceae; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guanidines; Lipids; Lysine; Pyruvaldehyde; Rats; Streptozocin | 2022 |
Methylglyoxal induces ambience for cancer promotion in HepG2 cells via Warburg effect and promotes glycation.
Topics: Glucose; Glycation End Products, Advanced; Hep G2 Cells; Humans; Magnesium Oxide; Neoplasms; Pyruvaldehyde; Reactive Oxygen Species | 2022 |