Compounds > pimagedine

pimagedine and omega-n-methylarginine

pimagedine has been researched along with omega-n-methylarginine in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's62 (65.26)18.2507
2000's29 (30.53)29.6817
2010's4 (4.21)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
Jeong, YS; Ryu, JH; Sohn, DH1
Caldwell, CG; Chabin, RM; Chen, P; Durette, PL; Esser, CK; Fletcher, D; Grant, SK; Green, BG; Guthikonda, R; Hagmann, WK; Humes, JL; Kelly, TM; Kopka, IE; Lanza, TJ; Luell, S; MacCoss, M; Meurer, R; Moore, V; Pacholok, SG; Pavia, T; Shah, SK; Williams, HR; Wong, KK1
Beaton, H; Hamley, P; Nicholls, DJ; Tinker, AC; Wallace, AV1
Chang, K; Corbett, JA; Hasan, KS; Ido, Y; Lancaster, JR; McDaniel, ML; Sweetland, MA; Tilton, RG; Wang, JL; Williamson, JR1
Allison, W; Chang, K; Corbett, JA; Hasan, K; Heesen, BJ; McDaniel, ML; Tilton, RG; Williamson, JR; Wolffenbuttel, BH1
Evans, TW; Griffiths, MJ; MacAllister, RJ; Messent, M1
Ayres, M; Chelly, F; Joly, GA; Kilbourn, RG1
Fries, KM; Geller, DA; Nussler, AK; Phipps, RP; Willis, RA1
Adashi, EY; Ben-Shlomo, I; Payne, DW1
Shukovski, L; Tsafriri, A1
Campbell, PA; Canono, BP; Drevets, DA; Leenen, PJ; Voerman, JS1
Bloom, BR; Carroll, D; Chan, J; Flynn, J; Tanaka, K1
Basha, F; Carter, GW; Esumi, H; Hokari, A; Klinghofer, V; Marsden, PA; Nakane, M; Ogura, T; Pollock, JS1
Agarwal, N; Chalasani, S; Lentz, KE; Lomis, TJ; Lowenstein, CJ; McMillan, A; Rhoads, JE; Siffring, CW; Stauffer, KE; Ziegler, DW1
Wu, G1
Carter, G; Tracey, WR; Tse, J1
Fedan, JS; Frazer, DG; Robinson, Va; Warner, TE; Yuan, LX1
Azad, AF; Green, SJ; Klotz, FW; Kumar, N; Marletta, MA; Scheller, LF; Seguin, MC1
Curzen, NP; Evans, TW; Griffiths, MJ; Liu, S; Messent, M1
Evans, SM; Laszlo, F; Whittle, BJ1
Gold, R; Hartung, HP; Jung, S; Liew, FY; Toyka, KV; Zielasek, J1
Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K; Settle, SL1
Balish, E; Jones-Carson, J; Vazquez-Torres, A; Warner, T1
Ahvazi, BC; Jacobs, P; Stevenson, MM1
Bauché, F; Guillemois, C; Jégou, B; Stéphan, JP1
Aubier, M; Bernard, C; Boczkowski, J; Desmonts, JM; Merval, R; Philip, I; Tedgui, A1
Chang, K; Corbett, JA; Currie, MG; Hasan, KS; McDaniel, ML; Misko, TP; Moore, WM; Petrash, JM; Smith, SR; Tilton, RG1
Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K1
Corbett, JA; Hickey, WF; McDaniel, ML; Misko, TP; Wang, JL; Zhao, W1
Hoffman, RA; Langrehr, JM; Mueller, AR; Neuhaus, P; Nussler, AK; Platz, KP; Schraut, WH1
Gregory, SH; Sagnimeni, AJ; Wing, EJ1
Thiemermann, C1
Adams, HR; Jones, JJ; Keller, RS; Kim, KF; Myers, PR; Parker, JL; Rubin, LJ1
Buffington, CW; Cook, DR; Kim, YM; Lancaster, JR; Müller, CM; Scierka, A; Stiller, RL; Watkins, WD1
Corbett, JA; McDaniel, ML1
Friedman, H; Klein, TW; Yamamoto, Y1
Grill, V; Möller, C; Tajiri, Y1
Coffey, JW; Evans, CH; Hoffman, RA; Meschter, C; Meyers, K; Stefanovic-Racic, M1
Davies, L; Denhardt, G; Donkin, J; Manfra, D; Smith, SR; Terminelli, C1
García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA1
Li, C; Lubeskie, A; Wolff, DJ1
Dave, S; Farrance, DP; Whitehead, SA1
Bjercke, RJ; Brock, TA; Chang, KC; Ido, Y; Kawamura, T; Stephan, CC; Tilton, RG; Williamson, JR1
Ishiguro, I; Nishida, K; Ohta, Y2
DeGeorge, GL; Heck, DE; Laskin, JD1
Pinto, A; Sautebin, L; Sorrentino, R1
Chang, K; Ferguson, TB; LeJeune, WS; Misko, TP; Sullivan, PM; Williamson, JR; Worrall, NK1
Geyer, O; Mittag, T; Podos, SM1
DeGeorge, GL; Gardner, CR; Heck, DE; Laskin, DL; Laskin, JD; Thomas, PE; Yang, CS; Zhang, XJ1
Gimeno, MA; Motta, AB1
Carpentier, PH; Desquand-Billiald, S; Finet, M; Gimeno, G; Hanf, R1
Damais, C; Dornand, J; Dugas, B; Dugas, N; Gross, A; Kolb, JP; Spiesser, S; Vouldoukis, I1
Gleichmann, M; Heneka, MT; Klockgether, T; Löschmann, PA; Schulz, JB; Weller, M; Wüllner, U1
Han, YN; Jeong, YS; Lee, HJ; Ryu, JH; Ryu, SY1
Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T1
Kameyama, T; Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Tanaka, T; Yamada, K1
Bories, PN; Gadano, AC; Heller, J; Lebrec, D; Moreau, R; Sogni, P1
Fukuyama, N; Hirabayashi, H; Nakazawa, H; Shinohara, Y; Takizawa, S1
Bhagat, K; Charles, IG; Hingorani, AD; Palacios, M; Vallance, P1
Aldasoro, M; Ballester, RM; Lluch, P; Lluch, S; Medina, P; Pelligrino, DA; Segarra, G; Vila, JM1
Chavez, AM; Fink, MP; Hodin, RA; Menconi, MJ1
Aizawa, H; Hara, N; Inoue, H; Kuwano, K; Matsumoto, K; Nadel, JA; Nakano, H1
Hori, M; Karaki, H; Kita, M; Ohota, S; Ozaki, H; Torihashi, S1
Cano, LE; de Gregori, W; Gonzalez, A; Restrepo, A; Velez, D1
Ram, JL; Speyer, CL; Steffes, CP; Tyburski, JG1
Bensard, DD; Fullerton, DA; Gamboni-Robertson, F; McIntyre, RC; Pulido, EJ; Selzman, CH; Shames, BD; Sheridan, BC1
Furusawa, S; Sakaguchi, S; Sasaki, K; Takayanagi, M; Takayanagi, Y; Yokota, K1
Holt, PG; Sly, PD; Tulić, MK; Wale, JL1
Ameshima, S; Demura, Y; Ishizaki, T; Matsukawa, S; Miyamori, I; Nakanishi, M; Okamura, S; Sasaki, F1
Farina, M; Franchi, AM; Gimeno, M; Ogando, D; Ribeiro, ML1
Russell, RJ1
El Mabrouk, M; Schiffrin, EL; Singh, A; Touyz, RM1
Bossone, C; Hosseini, JM; Piñeiro-Carrero, V; Shea-Donohue, T1
Chelly, JE; Doursout, MF; Hartley, CJ1
Jeong, TC; Joe, CO; Kim, YS; Lee, YH; Nam, KY; Park, JD; Park, KM; Shin, HJ1
Andric, SA; Kostic, TS; Stojilkovic, SS1
Hazama, K; Kawamata, M; Kawamata, T; Nakayaka, Y; Namiki, A; Omote, K; Toriyabe, M1
Hashimoto, M; Inoue, S; Ishibashi, Y; Katoh, H; Murakami, Y; Nakamura, K; Ohata, S; Ohta, Y; Sakane, T; Shimada, T; Shimizu, H; Sugamori, T; Takahashi, N1
Groeneveld, A; Saeij, JP; Van Muiswinkel, WB; Wiegertjes, GF1
Bucci, TJ; Hinson, JA; Irwin, LK; Mayeux, PR; Michael, SL1
Drakulic, D; Miljkovic, Dj; Samardzic, T; Stosic-Grujicic, S; Trajkovic, V1
Cox, R; Enkhbaatar, P; Hawkins, H; Herndon, D; Jodoin, J; Lee, S; McGuire, R; Mizutani, A; Murakami, K; Schmalstieg, F; Shimoda, K; Traber, D; Traber, L1
Ikegami, T; Kurane, I; Maeda, A; Morikawa, S; Niikura, M; Saijo, M1
Mitaka, C1
Gibson, DM; Kers, JA; Krasnoff, SB; Loria, R; Wach, MJ1
Groenendaal, F; Hagberg, HH; Heijnen, CJ; Kavelaars, A; Nijboer, CH; van Bel, F1
Borda, E; Furlan, C; Orman, B; Reina, S; Sterin-Borda, L1
Chelly, B; Chelly, JE; Doursout, MF; Fischer, UM; Hartley, CJ; Liang, Y; Oguchi, T1
Ishibashi, Y; Karino, K; Kodani, N; Kunizawa, Y; Murakami, Y; Oyake, N; Sakane, T; Sato, H; Shimada, T; Sugamori, T; Takahashi, N; Tokumaru, A; Yoshitomi, H1
Borda, E; Busch, L; Miozza, V; S-Borda, L1
Choe, J; Ha, KS; Jeoung, D; Kim, YM; Kwon, YG; Lee, DK; Lee, H; Lee, KS; Won, MH1
Han, YH; Jeon, SY; Kim, HS; Kwak, JY; Lee, NR; Rho, HW; Sohn, MH; Song, EK; Song, MY; Yang, SJ; Yhim, HY; Yim, CY; Yim, JM; Yim, JY; Yim, SK1
Coy, P; García-Vázquez, FA; Matás, C; Romero-Aguirregomezcorta, J; Santa, ÁP1

Reviews

2 review(s) available for pimagedine and omega-n-methylarginine

ArticleYear
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
    Progress in clinical and biological research, 1995, Volume: 392

    Topics: Animals; Arginine; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Shock, Septic; Thiourea

1995
[Septic shock and NO].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Animals; Biomarkers; Guanidines; Guanylate Cyclase; Hemodynamics; Humans; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Shock, Septic; Soluble Guanylyl Cyclase

2004

Trials

1 trial(s) available for pimagedine and omega-n-methylarginine

ArticleYear
Effects of some guanidino compounds on human cerebral arteries.
    Stroke, 1999, Volume: 30, Issue:10

    Topics: Adult; Aged; Arginine; Enzyme Inhibitors; Female; Guanidines; Humans; Male; Methylguanidine; Middle Aged; Middle Cerebral Artery; Nitric Oxide Synthase; omega-N-Methylarginine; Vasoconstrictor Agents; Vasodilator Agents

1999

Other Studies

92 other study(ies) available for pimagedine and omega-n-methylarginine

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
A new bisabolene epoxide from Tussilago farfara, and inhibition of nitric oxide synthesis in LPS-activated macrophages.
    Journal of natural products, 1999, Volume: 62, Issue:10

    Topics: Animals; Asteraceae; Cell Line; Lipopolysaccharides; Macrophage Activation; Macrophages; Medicine, Chinese Traditional; Mice; Nitric Oxide; Phytotherapy; Sesquiterpenes; Spectrum Analysis

1999
Substituted 2-aminopyridines as inhibitors of nitric oxide synthases.
    Bioorganic & medicinal chemistry letters, 2000, Sep-04, Volume: 10, Issue:17

    Topics: Aminopyridines; Enzyme Inhibitors; Humans; Nitric Oxide Synthase; Structure-Activity Relationship

2000
3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency.
    Bioorganic & medicinal chemistry letters, 2001, Apr-23, Volume: 11, Issue:8

    Topics: Animals; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoquinolines; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Protein Isoforms; Rats; Sensitivity and Specificity

2001
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction.
    Diabetes, 1992, Volume: 41, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Blood Vessels; Cells, Cultured; Diabetic Angiopathies; Enzyme Activation; Glucose; Guanidines; Insulin; Interleukin-1; Islets of Langerhans; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Regional Blood Flow

1992
Inhibition of nitric oxide formation by guanidines.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cell Line; Guanidines; In Vitro Techniques; Interleukin-1; Male; Mesenteric Arteries; Methylguanidine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasoconstriction

1993
Aminoguanidine selectively inhibits inducible nitric oxide synthase.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Cimetidine; Endothelium, Vascular; Endotoxins; Enzyme Induction; Guanidines; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Pyrilamine; Rats; Rats, Wistar

1993
Effects of NG-methyl-L-arginine, NG-nitro-L-arginine, and aminoguanidine on constitutive and inducible nitric oxide synthase in rat aorta.
    Biochemical and biophysical research communications, 1994, Feb-28, Volume: 199, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Enzyme Induction; Guanidines; Lipopolysaccharides; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Structure-Activity Relationship

1994
Induction of nitric oxide synthase in subsets of murine pulmonary fibroblasts: effect on fibroblast interleukin-6 production.
    Clinical immunology and immunopathology, 1994, Volume: 71, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Antigens, Surface; Arginine; Base Sequence; Cell Line; Cytokines; Enzyme Induction; Fibroblasts; Guanidines; Interleukin-6; Lung; Membrane Glycoproteins; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger; Thy-1 Antigens

1994
The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Dinoprostone; Female; Guanidines; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Ovary; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Transforming Growth Factor beta

1994
The involvement of nitric oxide in the ovulatory process in the rat.
    Endocrinology, 1994, Volume: 135, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Female; Guanidines; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ovulation; Rats; Rats, Wistar

1994
TNF-alpha and IFN-gamma stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Dec-01, Volume: 153, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Female; Guanidines; Interferon-gamma; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Necrosis Factor-alpha

1994
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.
    Infection and immunity, 1995, Volume: 63, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanidines; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tuberculosis

1995
Functional expression of three isoforms of human nitric oxide synthase in baculovirus-infected insect cells.
    Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Baculoviridae; Blotting, Western; Cell Line; Chromatography, Affinity; DNA, Complementary; Endothelium, Vascular; Enzyme Induction; Gene Expression; Guanidines; Humans; Isoenzymes; Kinetics; Mice; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Recombinant Proteins; Spodoptera; Transfection

1995
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
    The American surgeon, 1995, Volume: 61, Issue:1

    Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Guanidines; Humans; Hypotension; Immunohistochemistry; Male; Multiple Organ Failure; Nitric Oxide; omega-N-Methylarginine; Pancreatitis; Premedication; Rats; Rats, Sprague-Dawley; Resuscitation; Severity of Illness Index

1995
Nitric oxide synthesis and the effect of aminoguanidine and NG-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat.
    Diabetes, 1995, Volume: 44, Issue:3

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Type 1; Guanidines; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred BB; Species Specificity; Time Factors

1995
Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dexamethasone; Dose-Response Relationship, Drug; Guanidines; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors

1995
Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Airway Resistance; Amino Acid Oxidoreductases; Animals; Arginine; Epithelium; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Male; Methacholine Chloride; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Penicillamine; Respiration; S-Nitroso-N-Acetylpenicillamine; Trachea

1995
Co-localization of inducible-nitric oxide synthase and Plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Apr-01, Volume: 154, Issue:7

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Female; Fluorescent Antibody Technique; Guanidines; Liver; Malaria Vaccines; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plasmodium berghei; Primaquine; Rats; Rats, Inbred BN; Vaccines, Attenuated

1995
In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cyclic GMP; Dexamethasone; Endothelium, Vascular; Guanidines; Lipopolysaccharides; Male; Molecular Sequence Data; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Phosphatidylethanolamines; Potassium Chloride; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger

1995
Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo.
    European journal of pharmacology, 1995, Jan-16, Volume: 272, Issue:2-3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Capillary Permeability; Guanidines; Intestines; Male; Microcirculation; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar

1995
Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 1995, Volume: 58, Issue:1

    Topics: Acetates; Amino Acid Oxidoreductases; Animals; Arginine; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines; Mice; Mice, Inbred Strains; Myelin Basic Protein; Neuritis, Autoimmune, Experimental; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred Lew

1995
Nitric oxide and the cyclooxygenase pathway.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Dinoprostone; Enzyme Induction; Escherichia coli; Guanidines; Hydronephrosis; Indomethacin; Inflammation; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats

1995
Nitric oxide enhances resistance of SCID mice to mucosal candidiasis.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Candida albicans; Candidiasis; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Guanidines; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, SCID; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Recombinant Proteins

1995
Role of macrophage-derived nitric oxide in suppression of lymphocyte proliferation during blood-stage malaria.
    Journal of leukocyte biology, 1995, Volume: 58, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; DNA Primers; Female; Guanidines; Immune Tolerance; Lymphocyte Activation; Macrophages, Peritoneal; Malaria; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plasmodium chabaudi; Prostaglandins; Spleen

1995
Nitric oxide production by Sertoli cells in response to cytokines and lipopolysaccharide.
    Biochemical and biophysical research communications, 1995, Aug-04, Volume: 213, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Guanidines; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Sertoli Cells; Tumor Necrosis Factor-alpha

1995
Effects of inhibition of nitric oxide synthesis on TNF alpha serum levels in E. coli endotoxemic rats.
    Life sciences, 1995, Volume: 57, Issue:13

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli Infections; Guanidines; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Toxemia; Tumor Necrosis Factor-alpha

1995
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
    Diabetes, 1993, Volume: 42, Issue:2

    Topics: Aldehyde Reductase; Amino Acid Oxidoreductases; Animals; Arginine; Benzothiazoles; Blood Pressure; Body Weight; Capillary Permeability; Citrulline; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Imidazoles; Imidazolidines; Inositol; Iodine Radioisotopes; Male; Methylguanidine; Naphthalenes; Nitric Oxide Synthase; omega-N-Methylarginine; Phthalazines; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Serum Albumin, Bovine; Sorbitol; Thiazoles; Uvea

1993
Nitric oxide activates cyclooxygenase enzymes.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Aug-01, Volume: 90, Issue:15

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Dinoprostone; Enzyme Activation; Guanidines; Humans; Indomethacin; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins

1993
Nitric oxide mediates IL-1 beta-induced islet dysfunction and destruction: prevention by dexamethasone.
    Autoimmunity, 1993, Volume: 15, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dexamethasone; Guanidines; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley

1993
Function of nitric oxide during reperfusion of cold preserved small bowel grafts.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Analysis of Variance; Animals; Arginine; Cold Temperature; Glutaminase; Graft Survival; Guanidines; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Rats; Rats, Inbred Lew; Reperfusion

1994
Arginine analogues suppress antigen-specific and -nonspecific T lymphocyte proliferation.
    Cellular immunology, 1994, Volume: 153, Issue:2

    Topics: Animals; Antigens, Bacterial; Arginine; Canavanine; Female; Guanidines; Listeria monocytogenes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; T-Lymphocytes

1994
Endotoxin-induced myocardial dysfunction: is there a role for nitric oxide?
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:5

    Topics: Animals; Arginine; Enzyme Inhibitors; Guanidines; Guinea Pigs; Heart Atria; Immunoenzyme Techniques; Lipopolysaccharides; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic

1995
Nitric oxide mediates hepatic cytochrome P450 dysfunction induced by endotoxin.
    Anesthesiology, 1996, Volume: 84, Issue:6

    Topics: Animals; Arginine; Cytochrome P-450 Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Male; Microsomes, Liver; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley

1996
Selective inhibition of inducible nitric oxide synthase by aminoguanidine.
    Methods in enzymology, 1996, Volume: 268

    Topics: Animals; Arginine; Brain; Cell Line; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Guanidines; Iliac Artery; Insulinoma; Interleukin-1; Isoenzymes; Kinetics; Male; Molecular Structure; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley; Recombinant Proteins

1996
Immunoregulatory role of nitric oxide in Legionella pneumophila-infected macrophages.
    Cellular immunology, 1996, Aug-01, Volume: 171, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Female; Guanidines; Interferon-gamma; Interleukin-6; Legionella pneumophila; Macrophages, Peritoneal; Mice; Mice, Inbred A; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; RNA, Messenger

1996
Long-term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits B cell function.
    Endocrinology, 1997, Volume: 138, Issue:1

    Topics: Animals; Female; Glucose; Glycation End Products, Advanced; Guanidines; Insulin; Islets of Langerhans; omega-N-Methylarginine; Organ Culture Techniques; Rats; Rats, Wistar; RNA, Messenger

1997
Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis.
    The Journal of rheumatology, 1995, Volume: 22, Issue:10

    Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Cells, Cultured; Dose-Response Relationship, Drug; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Rats; Rats, Inbred Lew; Synovial Membrane

1995
Elevated levels of NO in both unchallenged and LPS-challenged C. parvum-primed mice are attributable to the activity of a cytokine-inducible isoform of iNOS.
    Journal of leukocyte biology, 1997, Volume: 61, Issue:1

    Topics: Animals; Guanidines; Interferon-gamma; Interleukin-10; Isoenzymes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Propionibacterium acnes; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha

1997
Bacterial infection induces nitric oxide synthase in human neutrophils.
    The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections

1997
Inactivation and recovery of nitric oxide synthetic capability in cytokine-induced RAW 264.7 cells treated with "irreversible" NO synthase inhibitors.
    Archives of biochemistry and biophysics, 1997, Feb-01, Volume: 338, Issue:1

    Topics: Animals; Biphenyl Compounds; Cell Line; Cytokines; Enzyme Inhibitors; Guanidines; Interferon-gamma; Kinetics; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Onium Compounds; Recombinant Proteins

1997
Evidence that nitric oxide inhibits steroidogenesis in cultured rat granulosa cells.
    Clinical science (London, England : 1979), 1997, Volume: 92, Issue:3

    Topics: Animals; Arginine; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Female; Granulosa Cells; Guanidines; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Progesterone; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1997
Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor.
    The Journal of clinical investigation, 1997, May-01, Volume: 99, Issue:9

    Topics: Animals; Calcimycin; Cell Membrane Permeability; Endothelial Growth Factors; Female; Glucose; Guanidines; Humans; Lymphokines; Male; Mice; Mice, Inbred BALB C; Nitroprusside; omega-N-Methylarginine; Rabbits; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Regional Blood Flow; Serum Albumin; Skin; Sorbitol; Superoxides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Role of gastric mucosal constitutive and inducible nitric oxide synthases in the development of stress-induced gastric mucosal lesions in rats.
    Biochemical and biophysical research communications, 1997, Jul-18, Volume: 236, Issue:2

    Topics: Animals; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Immersion; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

1997
Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors.
    Biochemical pharmacology, 1997, Jul-01, Volume: 54, Issue:1

    Topics: Animals; Arginine; Cell Line; Citrulline; Dose-Response Relationship, Drug; Guanidines; Interferon-gamma; Keratinocytes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured

1997
Effect of methylguanidine, guanidine and structurally related compounds on constitutive and inducible nitric oxide synthase activity.
    Life sciences, 1997, Volume: 61, Issue:13

    Topics: Animals; Cerebellum; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Guanidine; Guanidines; Isoenzymes; Lung; Male; Methylguanidine; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar

1997
TNF-alpha causes reversible in vivo systemic vascular barrier dysfunction via NO-dependent and -independent mechanisms.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Animals; Brain; Capillary Permeability; Endothelium, Vascular; Guanidines; Hemodynamics; Intestines; Liver; Lung; Male; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Recombinant Proteins; Regional Blood Flow; RNA, Messenger; Serum Albumin, Bovine; Skin; Transcription, Genetic; Tumor Necrosis Factor-alpha

1997
Nitric oxide synthase activity in tissues of the bovine eye.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1997, Volume: 235, Issue:12

    Topics: Animals; Antioxidants; Biopterins; Calmodulin; Canavanine; Cattle; Chelating Agents; Choroid; Ciliary Body; Edetic Acid; Enzyme Inhibitors; Female; Guanidines; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Retina; Trabecular Meshwork

1997
Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arginine; Cytochrome P-450 CYP2E1; Guanidines; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats

1998
Nitric oxide participates in the corpus luteum regression in ovaries isolated from pseudopregnant rats.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:12

    Topics: Analysis of Variance; Animals; Dinoprost; Enzyme Inhibitors; Female; Guanidines; Luteolysis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ovary; Progesterone; Pseudopregnancy; Rats; Rats, Wistar

1997
Histamine-induced biphasic macromolecular leakage in the microcirculation of the conscious hamster: evidence for a delayed nitric oxide-dependent leakage.
    British journal of pharmacology, 1998, Volume: 123, Issue:5

    Topics: Animals; Capillary Permeability; Cricetinae; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Histamine; Male; Mesocricetus; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Polysaccharides

1998
Nitric oxide production in human macrophagic cells phagocytizing opsonized zymosan: direct characterization by measurement of the luminol dependent chemiluminescence.
    Free radical research, 1998, Volume: 28, Issue:2

    Topics: Calcitriol; Cell Differentiation; Cell-Free System; Free Radical Scavengers; Guanidines; Humans; Immunoglobulin E; Immunoglobulin G; Leukemia, Monocytic, Acute; Luminescent Measurements; Luminol; Lymphoma, Large B-Cell, Diffuse; Macrophage Activation; Macrophages; Neoplastic Stem Cells; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Opsonin Proteins; Phagocytosis; Superoxide Dismutase; Superoxides; Tretinoin; Tumor Cells, Cultured; Xanthine; Xanthine Oxidase; Zymosan

1998
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: Animals; Apoptosis; Arginine; Biotin; Cell Differentiation; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Lipopolysaccharides; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; PC12 Cells; Rats; RNA, Messenger; Staining and Labeling; Thiazines; Transcription, Genetic; Tumor Necrosis Factor-alpha

1998
Relationship between constitutive nitric oxide synthase activity and mucus level in the gastric mucosa of rats with stress.
    Pharmacological research, 1998, Volume: 38, Issue:5

    Topics: Animals; Arginine; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Male; Mucus; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats; Rats, Wistar; Stress, Physiological

1998
Yomogin, an inhibitor of nitric oxide production in LPS-activated macrophages.
    Archives of pharmacal research, 1998, Volume: 21, Issue:4

    Topics: Animals; Artemisia; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Guanidines; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Plants, Medicinal; Sesquiterpenes; Sesquiterpenes, Eudesmane

1998
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
    Circulation, 1999, Feb-16, Volume: 99, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles

1999
Brain dysfunction associated with an induction of nitric oxide synthase following an intracerebral injection of lipopolysaccharide in rats.
    Neuroscience, 1999, Volume: 88, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Cycloheximide; Enzyme Induction; Guanidines; Hippocampus; Kinetics; Lipopolysaccharides; Male; Maze Learning; Memory; Microdialysis; Microinjections; Motor Activity; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Organ Specificity; Rats; Rats, Wistar; Time Factors

1999
Vascular nitric oxide production during the development of two experimental models of portal hypertension.
    Journal of hepatology, 1999, Volume: 30, Issue:5

    Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Guanidines; Hypertension, Portal; In Vitro Techniques; Liver Cirrhosis, Biliary; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Portal Vein; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombosis

1999
Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:6

    Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Guanidines; Half-Life; Hydrolysis; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tyrosine

1999
Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Adult; Arginine; Biopterins; Bradykinin; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Expression; Guanidines; Humans; Interleukin-1; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Shock, Septic; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

1999
Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide.
    Critical care medicine, 1999, Volume: 27, Issue:10

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Blotting, Northern; Caco-2 Cells; Cell Membrane Permeability; Culture Media; Enterocytes; Enzyme Inhibitors; Guanidines; Humans; Indicators and Reagents; Interferon-gamma; Interleukin-1; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha

1999
Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1

    Topics: Acetylcholine; Animals; Blotting, Northern; Bronchi; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Cells, Cultured; DNA Primers; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Guanidines; Guinea Pigs; Humans; In Situ Hybridization; Interleukin-8; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ozone; RNA, Messenger

2000
Resident macrophages activated by lipopolysaccharide suppress muscle tension and initiate inflammatory response in the gastrointestinal muscle layer.
    Histochemistry and cell biology, 2000, Volume: 113, Issue:2

    Topics: Animals; Carbachol; Cell Movement; Dextrans; Digestive System; Enzyme Inhibitors; Female; Fluorescein-5-isothiocyanate; Guanidines; Histocompatibility Antigens Class II; Immunohistochemistry; Intestinal Mucosa; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Microscopy, Confocal; Muscle Contraction; Muscle, Smooth; Myositis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Wistar; Time Factors

2000
Nitric oxide participation in the fungicidal mechanism of gamma interferon-activated murine macrophages against Paracoccidioides brasiliensis conidia.
    Infection and immunity, 2000, Volume: 68, Issue:5

    Topics: Animals; Arginase; Enzyme Inhibitors; Guanidines; Interferon-gamma; Intracellular Fluid; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paracoccidioides

2000
Lipopolysaccharide induces relaxation in lung pericytes by an iNOS-independent mechanism.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5

    Topics: Animals; Capillaries; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Nitroprusside; omega-N-Methylarginine; Penicillamine; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Spermine; Vasodilator Agents

2000
Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:5

    Topics: Animals; Aorta; Enzyme Inhibitors; Fluorescent Antibody Technique; Guanidines; Immunoblotting; Lipopolysaccharides; Male; Muscle Contraction; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Salmonella typhimurium; Tissue Distribution

2000
Effect of nitric oxide synthase inhibitors on lipid peroxide formation in liver caused by endotoxin challenge.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:4

    Topics: Animals; Antioxidants; Cell Count; Cell Line; Cell Survival; Endotoxins; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Lipid Peroxides; Lipopolysaccharides; Liver; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Sulfhydryl Compounds; Superoxides; Survival Rate

2000
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
    The European respiratory journal, 2000, Volume: 15, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea

2000
Leukotoxin, 9,10-epoxy-12-octadecenoate, causes pulmonary vasodilation by stimulation of vascular eNOS and iNOS.
    Lung, 2000, Volume: 178, Issue:3

    Topics: Animals; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Exotoxins; Guanidines; Humans; Linoleic Acids; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasodilation

2000
IL1alpha augments prostaglandin synthesis in pregnant rat uteri by a nitric oxide mediated mechanism.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 62, Issue:4

    Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Guanidines; Interleukin-1; Interleukin-2; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus

2000
Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 100

    Topics: Animals; Aorta, Thoracic; Arginine; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Phenylephrine; Rats; Rats, Wistar

1998
Antiproliferative effect of L-NAME on rat vascular smooth muscle cells.
    Life sciences, 2000, Aug-18, Volume: 67, Issue:13

    Topics: Animals; Arginine; Becaplermin; Cell Division; Culture Media; DNA; Drug Interactions; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Thymidine

2000
Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:5

    Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Guanidines; In Vitro Techniques; Inflammation; Inflammatory Bowel Diseases; Male; Muscle Contraction; Muscle, Smooth; NADPH Dehydrogenase; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors; Trinitrobenzenesulfonic Acid

2001
Comparison of cardiac and regional hemodynamic responses to N-methyl-L-arginine and aminoguanidine infusions in conscious pigs.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:4

    Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Guanidines; Heart; Heart Rate; Hemodynamics; Nitric Oxide Synthase; omega-N-Methylarginine; Regional Blood Flow; Swine; Vascular Resistance; Vasodilation

2001
Nitric oxide is involved in the immunomodulating activities of acidic polysaccharide from Panax ginseng.
    Planta medica, 2001, Volume: 67, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antibody-Producing Cells; Cells, Cultured; Concanavalin A; Enzyme Induction; Enzyme Inhibitors; Female; Guanidines; Interferon-gamma; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Panax; Plant Lectins; Plant Roots; Plants, Medicinal; Polysaccharides; Spleen

2001
Spontaneous and receptor-controlled soluble guanylyl cyclase activity in anterior pituitary cells.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gonadotropin-Releasing Hormone; Growth Hormone-Releasing Hormone; Guanidines; Guanylate Cyclase; Immunoblotting; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thyrotropin-Releasing Hormone

2001
Peripheral nitric oxide in carrageenan-induced inflammation.
    Brain research, 2001, Sep-07, Volume: 912, Issue:2

    Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflammation; Injections, Subcutaneous; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors

2001
An inhibitor of inducible nitric oxide synthase decreases forearm blood flow in patients with congestive heart failure.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: Acetylcholine; Adult; Aged; Analysis of Variance; Atrial Natriuretic Factor; Blood Flow Velocity; Case-Control Studies; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Endothelium, Vascular; Female; Forearm; Guanidines; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Severity of Illness Index; Time Factors; Vasodilation

2001
Immune modulation by fish kinetoplastid parasites: a role for nitric oxide.
    Parasitology, 2002, Volume: 124, Issue:Pt 1

    Topics: Animals; Carps; Cell Division; Enzyme Inhibitors; Fish Diseases; Guanidines; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Phagocytosis; S-Nitroso-N-Acetylpenicillamine; Trypanosoma

2002
Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.
    Nitric oxide : biology and chemistry, 2002, Volume: 6, Issue:2

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Drug Interactions; Enzyme Inhibitors; Guanidines; Liver; Lysine; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

2002
Immunosuppressants leflunomide and mycophenolic acid inhibit fibroblast IL-6 production by distinct mechanisms.
    Cytokine, 2002, Aug-21, Volume: 19, Issue:4

    Topics: Aniline Compounds; Animals; Cell Line; Cell Survival; Cells, Cultured; Coloring Agents; Crotonates; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Guanidines; Humans; Hydroxybutyrates; Immunosuppressive Agents; Interferon-gamma; Interleukin-6; Isoxazoles; Leflunomide; Macrophages; Mice; Mycophenolic Acid; Nitric Oxide Synthase; Nitriles; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Rolipram; Tetrazolium Salts; Thiazoles; Time Factors; Toluidines

2002
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:2

    Topics: Acute Disease; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Guanidines; Indazoles; Lung Diseases; Nitric Oxide Synthase; omega-N-Methylarginine; Pneumonia, Bacterial; Sheep, Domestic; Smoke

2003
Modification of endothelial cell functions by Hantaan virus infection: prolonged hyper-permeability induced by TNF-alpha of hantaan virus-infected endothelial cell monolayers.
    Archives of virology, 2004, Volume: 149, Issue:7

    Topics: Boron Compounds; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hantaan virus; Humans; Indomethacin; Interleukin-6; Methacrylates; Methylmethacrylates; Nitric Oxide; omega-N-Methylarginine; Permeability; Prostaglandins; Recombinant Proteins; Tumor Necrosis Factor-alpha; Umbilical Veins

2004
Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp.
    Nitric oxide : biology and chemistry, 2005, Volume: 12, Issue:1

    Topics: Arginine; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Indazoles; Indoles; Molecular Structure; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Piperazines; Streptomyces

2005
Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:2

    Topics: Animals; Animals, Newborn; Biotin; Blotting, Western; Caspases; Enzyme Inhibitors; Female; Guanidines; HSP70 Heat-Shock Proteins; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pregnancy; Rats; Rats, Wistar; Sex Characteristics; Signal Transduction; Tyrosine

2007
Differential signalling pathways involved in cholinoceptor-dependent stimulation of nitric oxide isoforms in dental pulp.
    International endodontic journal, 2007, Volume: 40, Issue:7

    Topics: Animals; Arginine; Calmodulin; Dental Pulp; Enzyme Inhibitors; Guanidines; Male; Muscarinic Agonists; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pilocarpine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases

2007
Distribution of NOS isoforms in a porcine endotoxin shock model.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:6

    Topics: Animals; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Hemodynamics; Hypotension; Isoenzymes; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Specificity; Shock, Septic; Swine; Vasoconstriction; Vasodilation; Vasodilator Agents

2008
Activation of inducible NOS in peripheral vessels and outcomes in heart failure patients.
    Journal of cardiac failure, 2008, Volume: 14, Issue:9

    Topics: Acetylcholine; Aged; Blood Flow Velocity; Cardiomyopathy, Dilated; Dose-Response Relationship, Drug; Enzyme Activation; Female; Follow-Up Studies; Forearm; Guanidines; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitroglycerin; omega-N-Methylarginine; Prospective Studies; Treatment Outcome; Vasoconstrictor Agents

2008
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
    Oral diseases, 2010, Volume: 16, Issue:8

    Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles

2010
Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.
    Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1

    Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Lysine; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Protein Multimerization; Substrate Specificity

2012
Lymphocyte-mediated macrophage apoptosis during IL-12 stimulation.
    Cytokine, 2013, Volume: 64, Issue:1

    Topics: Animals; Antibodies, Blocking; Apoptosis; Benzoates; Caspase 3; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Coculture Techniques; Guanidines; Imidazoles; Interferon-gamma; Interleukin-12; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; PTEN Phosphohydrolase; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2013
Nitric oxide synthase (NOS) inhibition during porcine in vitro maturation modifies oocyte protein S-nitrosylation and in vitro fertilization.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Animals; Enzyme Inhibitors; Female; Fertilization in Vitro; Guanidines; In Vitro Oocyte Maturation Techniques; Meiosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oocytes; Protein S; Swine

2014