pimagedine has been researched along with nitrites in 147 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 57 (38.78) | 18.2507 |
| 2000's | 73 (49.66) | 29.6817 |
| 2010's | 16 (10.88) | 24.3611 |
| 2020's | 1 (0.68) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, JD; DeMeester, SR; Ferguson, TB; Misko, TP; Patterson, GA; Ritter, JH; Shiraishi, T; Worrall, NK | 1 |
| Giles, TD; Greenberg, SS; Grisham, MB; Lancaster, J; Powers, DR; Spitzer, JJ; Wang, JF; Xie, J | 1 |
| Allison, W; Chang, K; Corbett, JA; Hasan, K; Heesen, BJ; McDaniel, ML; Tilton, RG; Williamson, JR; Wolffenbuttel, BH | 1 |
| Adcock, IM; Buttery, LD; Kwon, OJ; Moncada, S; Polak, J; Riveros-Moreno, V; Robbins, RA; Springall, DR; Warren, JB; Wilson, AJ | 1 |
| Cross, AH; Hickey, WF; Lin, RF; Misko, TP; Tilton, RG; Trotter, JL | 1 |
| Adashi, EY; Ben-Shlomo, I; Payne, DW | 1 |
| Carter, G; Tracey, WR; Tse, J | 1 |
| Connor, JR; Currie, MG; Jerome, GM; Manning, PT; Moore, WM; Settle, SL; Tjoeng, FS; Webber, RK | 1 |
| Bauché, F; Guillemois, C; Jégou, B; Stéphan, JP | 1 |
| Beckman, JS; Eloby-Childress, S; Kakkis, JL; Miller, MJ; Munshi, UK; Rossi, JL; Sadowska-Krowicka, H; Sandoval, M; Thompson, JH; Zhang, XJ | 1 |
| Corbett, JA; Currie, MG; Kasten, TP; McDaniel, ML; Misko, TP; Moore, WM; Nickols, GA; Tilton, RG; Williamson, JR | 1 |
| Kassell, NF; Lee, KS; Suzuki, S; Takenaka, K | 1 |
| Berry, LM; Hoffman, RA; Langrehr, JM; McCarthy, SA; Schattenfroh, NC; Simmons, RL; White, DA | 1 |
| Olsen, R; Seljelid, R; Seternes, OM; Sveinbjørnsson, B | 1 |
| Grogan, JB; Joshi, PC; Thomae, KR | 1 |
| Boyle, P; Courcoulas, A; Ford, HR; Friend, C; Garrett, M; Koltuksuz, U; Rowe, MI; Sorrells, DL; Watkins, S | 1 |
| Chou, TC; Ding, YA; Hong, HJ; Wu, CC; Yen, MH | 1 |
| Hata, I; Hata, K; Ishii, Y; Miura, M; Muramatsu, I; Sudo, M; Tsuchida, S; Tsukahara, H; Yamamoto, K | 1 |
| Campbell, IL | 1 |
| Davies, L; Denhardt, G; Donkin, J; Manfra, D; Smith, SR; Terminelli, C | 1 |
| Busch, C; Dirnagl, U; Freyer, D; Isaev, N; Megow, D; Schultze, J; Weih, M; Weikert, S | 1 |
| Dave, S; Farrance, DP; Whitehead, SA | 1 |
| Hong, HJ; Liu, YC; Sheu, JR; Wu, CC; Yen, MH | 1 |
| Boku, Y; Fujii, T; Hongo, H; Kondo, M; Nakahashi, Y; Takano, H; Yamaguchi, T; Yamamoto, H; Yanagisawa, R; Yoshida, N; Yoshikawa, T | 1 |
| Hock, CE; Wong, PY; Yin, K; Yue, G | 1 |
| Ahokas, RA; Friedman, SA; Lubarsky, SL; Sibai, BM | 1 |
| Ferro, TJ; Gertzberg, N; Johnson, A; Neumann, P; Selden, L | 1 |
| Allen, PC | 1 |
| LeDoux, SP; Patton, NJ; Wilson, GL | 1 |
| Kauser, K; Rubanyi, GM; Sonnenberg, D; Tse, J | 1 |
| Freeman, T; Giles, TD; Greenberg, SS; Hua, L; Kapusta, DR; Lancaster, JR; Powers, DR; Sarphie, TG; Xie, J; Zhao, X | 1 |
| Chavez, A; Fink, MP; Hodin, RA; Larkin, V; Menconi, MJ; Morin, MJ; Smith, M; Tytgat, SH; Unno, N; Wang, H | 1 |
| Bjerrum, OJ; Cooper, ME; Jerums, G; Panagiotopoulos, S; Sastra, S; Soulis, T; Thallas, V | 1 |
| Granger, DN; Grisham, MB; Komatsu, S; Russell, JM | 1 |
| Kato, I; Kimura, N; Nakazawa, T; Okamoto, H; Takamura, T; Takasawa, S; Yonekura, H | 1 |
| Chen, L; Harris, DC; Zhang, BH | 1 |
| Goldberg, MB; Way, SS | 1 |
| Cejas, H; Cervi, L; Masih, DT; Rossi, G | 1 |
| Barrera, LF; García, LF; Rojas, M | 1 |
| Ishiguro, I; Nishida, K; Ohta, Y | 3 |
| Elson, G; Legarda, D; Leibovich, SJ; Xiong, M | 1 |
| Huang, CC; Ko, YC; Yang, CW; Yu, CC | 1 |
| Chouaib, S; Dugas, B; Dugas, N; Kolb, JP; Salvucci, O | 1 |
| Muriel, P | 1 |
| Boulu, RG; Lecanu, L; Margaill, I; Plotkine, M; Verrecchia, C | 1 |
| Abacioglu, N; Altug, S; Tunçtan, B; Uludag, O | 1 |
| Hwang, CP; Shum, AY; Wang, JY | 1 |
| Eisenstein, TK; MacFarlane, AS; Schwacha, MG | 1 |
| Hua, TC; Moochhala, SM | 2 |
| Kameyama, T; Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Tanaka, T; Yamada, K | 1 |
| Kondo, M; Nagashima, Y; Sekihara, H; Tanaka, K; Tanaka, N | 1 |
| Horiuchi, S; Makino, H; Shikata, K; Sugimoto, H; Wada, J | 1 |
| Andric, SA; Kostic, TS; Kovacevic, R; Maric, D; Stojilkovic, SS | 1 |
| Blais, S; Bouchard, L; Desrosiers, C; Lacasse, P; Zhao, X | 1 |
| Kim, JC; Kim, MK; Ko, SM | 1 |
| Fariss, MW; Nicholls-Grzemski, FA; Schmittgen, TD; Tirmenstein, MA; Zakrajsek, BA | 1 |
| Ikeda, U; Kurosaki, K; Maeda, Y; Shimada, K | 1 |
| Anderson, F; Bekker, S; Collin-Osdoby, P; Osdoby, P; Rothe, L | 1 |
| Kawasaki, T; Masuda, Y; Matsuzaki, K; Okamoto, T; Shinohara, M | 1 |
| Hoffman, R; Langrehr, JM; Leder, K; Machens, C; Neuhaus, P; Nüssler, A; Zill, E | 1 |
| Grover, VS; Sharma, A; Singh, M | 1 |
| Benyó, Z; Görlach, C; Hortobágyi, T; Wahl, M | 1 |
| Billiau, A; Matthys, P; Thielemans, L; Vermeire, K | 1 |
| Bertsch, T; Fassbender, K; Fatar, M; Hennerici, M; Kuehl, S; Picard, M; Ragoschke, A | 1 |
| Baranda, P; Blasco, MR; Castejón, R; García-Merino, A; Martínez, I; Puerta, C; Vargas, JA | 1 |
| Cason, GW; Manning, RD; Meng, S; Tan, DY | 1 |
| Ismailoglu, UB; Sahin-Erdemli, I; Sayek, I; Yorganci, K | 1 |
| Kagota, S; Kunitomo, M; Nakamura, K; Yamaguchi, Y | 1 |
| Briot, T; Laubriet, A; Lecour, S; Maupoil, V; Rochette, L; Zeller, M | 1 |
| Carey, DJ; Elmore, JR; Franklin, DP; Han, DC; Johanning, JM | 1 |
| Bredt, DS; Kobzik, L; Reid, MB; Stamler, JS | 1 |
| Bekker, LG; Freeman, S; Kaplan, G; Murray, PJ; Ryffel, B | 1 |
| Diez-Orejas, R; Gil, C; Molero, G; Moro, MA; Nombela, C; Sánchez-Pérez, M | 1 |
| Barbera, A; Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fonti, MT; Mazzon, E | 1 |
| Hori, R; Ito, Y; Nabekura, T; Nakao, M; Takeda, M; Terao, M; Tomohiro, M | 1 |
| Grill, V; Tajiri, Y | 1 |
| Fu, Y; Lei, XG; McCormick, CC; Roneker, C | 1 |
| Hazama, K; Kawamata, M; Kawamata, T; Nakayaka, Y; Namiki, A; Omote, K; Toriyabe, M | 1 |
| Hataishi, R; Hayashi, I; Imasaki, T; Kobayashi, H; Majima, M; Tomita, T | 1 |
| Dikshit, M; Sethi, S; Sharma, P | 1 |
| Folkerts, G; Muijsers, RB; Nijkamp, FP; Postma, DS; ten Hacken, NH; Van Ark, I | 1 |
| Dikshit, M; Raghavan, SA | 1 |
| Baatz, H; Pleyer, U | 1 |
| Groeneveld, A; Saeij, JP; Van Muiswinkel, WB; Wiegertjes, GF | 1 |
| Barja-Fidalgo, C; Cristina de Assis, M; Cristina Plotkowski, M; de Freitas, MS; Fierro, IM | 1 |
| Cella, M; Franchi, AM; Ogando, DG; Paz, D | 1 |
| Colasanti, M; Cuzzocrea, S; Dugo, L; Musci, G; Persichini, T | 1 |
| Hirata, K; Isobe, M; Katsuramaki, T; Kimura, H; Kukita, K; Meguro, M; Nagayama, M; Nui, A | 1 |
| Ni, Z; Vaziri, ND | 1 |
| Md, S; Moochhala, SM; Siew-Yang, KL | 1 |
| Aktan, F; Ammit, AJ; Henness, S; Roufogalis, BD | 1 |
| Aydin, S; Büyükafşar, K; Caglikülekçi, M; Cinel, I; Cinel, L; Dirlik, M; Oral, U; Tamer, L | 1 |
| Ibáñez de Cáceres, I; López-Calderón, A; Martín, AI; Priego, T; Villanúa, MA | 1 |
| Canová, N; Farghali, H; Kucera, T; Martínek, J; Masek, K | 1 |
| Bezerra, MM; Brain, SD; da Rocha, FA; de Melo, LB; Greenacre, S; Jerônimo, SM; Keeble, J | 1 |
| Atan, MS; Low, K; Lu, J; Moochhala, SM; Ng, KC; Teo, AL | 1 |
| Bryson, JS; Cohen, DA; Hongo, D; Kaplan, AM | 1 |
| Darville, MI; De Ridder, M; Eizirik, DL; Monsaert, C; Storme, GA; Van Den Berge, DL; Verovski, VN | 1 |
| Mitaka, C | 1 |
| Lu, J; Mok, P; Moochhala, SM; Ng, KC; Shirhan, M; Siew Yang, KL; Sng, J | 1 |
| Chen, JJ; Cheng, PY; Yen, MH | 1 |
| Lin, HC; Tung, CS; Wan, FJ; Wu, CC; Wu, TH | 1 |
| Anuar, F; Lu, J; Md, S; Mok, P; Moochhala, SM; Ng, KC; Siew Yang, KL | 1 |
| Ding, HL; Dong, JW; Yang, HT; Yang, WW; Zhou, ZN; Zhu, HF; Zhu, WZ | 1 |
| Bonartsev, AP; D'iakonov, KB; Medvedeva, NA; Postnikov, AB; Slavutskaia, AV | 1 |
| Chao, KF; Lin, WW; Lin-Shiau, SY; Liu, SH; Sheu, ML; Sung, YJ | 1 |
| Chen, SY; Cheng, PY; Hong, SF; Lam, KK; Lee, YM; Sheu, JR; Yen, MH | 1 |
| Gilani, RA; Masood, A; Masood, N; Nadeem, A; Shah, ZA | 1 |
| Akalin, S; Burçak, G; Cetinel, S; Civelek, S; Deyneli, O; Haklar, G; Kaya, H; San, T; Tuğtepe, H; Uyar, S; Yavuz, D | 1 |
| Hazlett, LD; Lighvani, S; McClellan, SA | 1 |
| Gupta, YK; Kumar, A; Patel, S; Singh, MP | 1 |
| Borges, AH; Camargos, ER; Cunha, FQ; Machado, CR; Neves, SR; Pinto, AM | 1 |
| Abdel-Hady, RH; Abdel-Rahman, S; Abdel-Zaher, AO; Aly, SA; Hamdy, MM | 1 |
| Castillero, E; Granado, M; López-Calderón, A; Martín, AI; Priego, T; Villanúa, MA | 1 |
| Bopp, Ch; Gries, A; Gust, R; Klein, A; Martin, E; Taut, F | 1 |
| Karayilanoglu, T; Korkmaz, A; Kurt, B; Mollaoglu, H; Oter, S; Topal, T; Yaren, H | 1 |
| Atmaca, M; Bilgin, HM; Diken, H; Kelle, M; Obay, BD; Tümer, C | 1 |
| Casais, M; Delgado, SM; Rastrilla, AM; Sosa, Z; Vallcaneras, S | 1 |
| Goto, E; Kang, KS; Tanaka, T; Yamabe, N; Yokozawa, T | 1 |
| Joharchi, K; Jorjani, M | 1 |
| Bonaventura, D; Celotto, AC; Cherri, J; Evora, PR; Joviliano, EE; Moryia, T; Piccinato, CE; Viaro, F | 1 |
| Dudhgaonkar, SP; Kataria, M; Kumar, D; Raviprakash, V; Tandan, SK | 1 |
| Agar, A; Akpinar, D; Aslan, M; Derin, N; Yargicoglu, P | 1 |
| Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S | 1 |
| Kim, JA; Xu, X; Zuo, Z | 1 |
| Huang, EY; Lin, IH; Wang, FS; Yang, KD | 1 |
| Dhingra, D; Gilhotra, N | 3 |
| Irwin, MG; Liu, HM; Luo, T; Vanhoutte, PM; Wang, F; Xia, Z; Xia, ZY | 1 |
| Gupta, SP; Patel, S; Singh, AK; Singh, MP; Singh, S; Yadav, S | 1 |
| Dhingra, D; Gilhotra, N; Jain, H | 1 |
| Giannoulaki, V; Papathanassiou, M; Tiligada, E; Zampeli, E | 1 |
| Chhillar, R; Dhingra, D | 1 |
| Anuradha, CV; Radika, MK; Viswanathan, P | 1 |
| Errea, A; Hozbor, D; Moreno, G; Ormazabal, M; Rumbo, M; Zurita, E | 1 |
| Almeida, R; Duarte, ID; Fontes, MA; Galdino, GS; Menezes, G; Perez, AC; Silva, G; Xavier, CH | 1 |
| Abbasi, A; Dehpour, AR; Fakhfouri, G; Fakhraei, N; Ghia, JE; Heydarpour, P; Khoshkish, S; Rahimian, R; Salehi-Sadaghiani, M; Wang, H | 1 |
| Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A | 1 |
| Fatemikia, H; Karimi, Z; Ketabchi, F; Moosavi, SM | 1 |
| Chamanara, M; Dehpour, AR; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Shakiba, S; Zolfaghari, S | 1 |
| Biojone, C; Casarotto, PC; Fernandes, GG; Guimarães, FS; Joca, SRL; Pinheiro, LC; Ribeiro, DE; Spiacci, AJ; Tanus-Santos, JE; Zangrossi, HJ | 1 |
| Augello, FR; Cifone, MG; Cinque, B; Giuliani, M; Lombardi, F; Mattei, A; Palumbo, P | 1 |
| Aguiar, DC; de Oliveira, ACP; Ferreira, AVM; Gomes, GF; Gomes, JAS; Marçal, AP; Oliveira, MC; Silva, GC; Silva, JF; Soares, VL | 1 |
1 review(s) available for pimagedine and nitrites
| Article | Year |
|---|---|
[Septic shock and NO].
Topics: Animals; Biomarkers; Guanidines; Guanylate Cyclase; Hemodynamics; Humans; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Shock, Septic; Soluble Guanylyl Cyclase | 2004 |
146 other study(ies) available for pimagedine and nitrites
| Article | Year |
|---|---|
Inhibition of inducible nitric oxide synthase ameliorates rat lung allograft rejection.
Topics: Animals; Graft Rejection; Guanidines; Lung; Lung Transplantation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Radiography; Random Allocation; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous | 1995 |
Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.
Topics: Animals; Arginine; Enzyme Inhibitors; Evaluation Studies as Topic; Guanidines; Luminescent Measurements; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ornithine; Rats; Rats, Sprague-Dawley; Triazines | 1995 |
Inhibition of nitric oxide formation by guanidines.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cell Line; Guanidines; In Vitro Techniques; Interleukin-1; Male; Mesenteric Arteries; Methylguanidine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1993 |
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Guanidines; Interferon-gamma; Interleukin-1; Kinetics; Lung; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
Topics: Amino Acid Oxidoreductases; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Spinal Cord | 1994 |
The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Dinoprostone; Female; Guanidines; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Ovary; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Transforming Growth Factor beta | 1994 |
Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dexamethasone; Dose-Response Relationship, Drug; Guanidines; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arthritis, Experimental; Blood Pressure; Enzyme Induction; Guanidines; Immunohistochemistry; Joints; Lysine; Male; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred Lew; Synovial Fluid | 1995 |
Nitric oxide production by Sertoli cells in response to cytokines and lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Guanidines; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Sertoli Cells; Tumor Necrosis Factor-alpha | 1995 |
Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Disease Models, Animal; Enzyme Induction; Female; Gene Expression; Guanidines; Guinea Pigs; Ileitis; Immunohistochemistry; Male; Molecular Sequence Data; Nitric Oxide Synthase; Nitrites; Tyrosine | 1995 |
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Hemoglobin augmentation of interleukin-1 beta-induced production of nitric oxide in smooth-muscle cells.
Topics: Animals; Aorta, Thoracic; Arginine; Cell Hypoxia; Cells, Cultured; Cycloheximide; Guanidines; Hemoglobins; Humans; Hydrocortisone; Interleukin-1; Iron; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroarginine; Rats | 1994 |
Bystander injury of host lymphoid tissue during murine graft-verus-host disease is mediated by nitric oxide.
Topics: Animals; Body Weight; Cell Transplantation; Cytotoxicity, Immunologic; Enzyme Inhibitors; Female; Graft vs Host Disease; Granulocyte-Macrophage Colony-Stimulating Factor; Guanidines; Lymphocyte Subsets; Lymphocytes; Lymphoid Tissue; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrates; Nitric Oxide; Nitrites; Spleen | 1996 |
Macrophage cytotoxicity against murine meth A sarcoma involves nitric oxide-mediated apoptosis.
Topics: Animals; Apoptosis; beta-Glucans; Cells, Cultured; Coculture Techniques; Female; Glucans; Guanidines; Interferon Inducers; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Electron; Microscopy, Electron, Scanning; Nitric Oxide; Nitrites; Nitroprusside; Recombinant Proteins; Sarcoma, Experimental; Tumor Cells, Cultured | 1996 |
Effect of aminoguanidine on in vivo expression of cytokines and inducible nitric oxide synthase in the lungs of endotoxemic rats.
Topics: Animals; Base Sequence; Cytokines; Endotoxins; Enzyme Inhibitors; Guanidines; Interleukin-1; Lipopolysaccharides; Lung; Male; Molecular Sequence Data; Nitric Oxide Synthase; Nitrites; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 1996 |
Inhibition of nitric oxide with aminoguanidine reduces bacterial translocation after endotoxin challenge in vivo.
Topics: Animals; Bacterial Translocation; Cecum; Cell Membrane Permeability; Endotoxins; Enzyme Inhibitors; Epithelium; Escherichia coli; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Guanidines; Intestinal Mucosa; Lipopolysaccharides; Liver; Lymph Nodes; Male; Membrane Potentials; Mesentery; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Spleen; Up-Regulation | 1996 |
Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Cyclic GMP; Enzyme Induction; Guanidines; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 1996 |
Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats.
Topics: Absorptiometry, Photon; Aging; Animals; Blood Pressure; Body Weight; Bone and Bones; Bone Density; Endotoxins; Guanidines; Lumbosacral Region; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spine | 1996 |
Exacerbation of lymphocytic choriomeningitis in mice treated with the inducible nitric oxide synthase inhibitor aminoguanidine.
Topics: Animals; Brain; Cytokines; Guanidines; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide Synthase; Nitrites | 1996 |
Elevated levels of NO in both unchallenged and LPS-challenged C. parvum-primed mice are attributable to the activity of a cytokine-inducible isoform of iNOS.
Topics: Animals; Guanidines; Interferon-gamma; Interleukin-10; Isoenzymes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Propionibacterium acnes; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Rapid Ca2+-dependent NO-production from central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence.
Topics: Animals; Brain; Calcimycin; Calcium; Cells, Cultured; Enzyme Inhibitors; Glutamic Acid; Guanidines; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ozone; Potassium Chloride; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tissue Distribution | 1997 |
Evidence that nitric oxide inhibits steroidogenesis in cultured rat granulosa cells.
Topics: Animals; Arginine; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Female; Granulosa Cells; Guanidines; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Progesterone; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Role of nitric oxide in lipopolysaccharide-induced mortality from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Guanidines; Hypertension; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Survival Rate | 1997 |
Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats.
Topics: Animals; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Activating Factor; Rats; Systemic Inflammatory Response Syndrome | 1997 |
Effects of inhibition of nitric oxide synthase by aminoguanidine in acute endotoxemia.
Topics: Acute Disease; Animals; Endotoxemia; Enzyme Inhibitors; Guanidines; Hemodynamics; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxides | 1997 |
The effect of chronic nitric oxide synthesis inhibition on blood pressure and angiotensin II responsiveness in the pregnant rat.
Topics: Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Female; Guanidines; Heart Rate; Hematocrit; Kinetics; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Pregnancy; Proteinuria; Rats; Rats, Inbred WKY | 1997 |
Endothelial barrier dysfunction and p42 oxidation induced by TNF-alpha are mediated by nitric oxide.
Topics: Actins; Animals; Antibodies; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hydrazones; Molecular Weight; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Serum Albumin; Spermine; Tumor Necrosis Factor-alpha; Tyrosine | 1997 |
Nitric oxide production during Eimeria tenella infections in chickens.
Topics: Animals; Body Weight; Cecum; Chickens; Coccidiosis; Eimeria tenella; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hemorrhage; Injections, Intraperitoneal; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Poultry Diseases; Vasodilation | 1997 |
Mitochondrial DNA in beta-cells is a sensitive target for damage by nitric oxide.
Topics: Animals; Animals, Newborn; Autoradiography; Blotting, Southern; Cells, Cultured; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Inhibitors; Guanidines; Interleukin-1; Islets of Langerhans; Mutagens; Nitrites; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spermine | 1997 |
17 beta-Estradiol attenuates endotoxin-induced excessive nitric oxide production in ovariectomized rats in vivo.
Topics: Analysis of Variance; Animals; Dexamethasone; Estradiol; Female; Guanidines; Lipopolysaccharides; Nitric Oxide; Nitrites; Ovariectomy; Rats; Rats, Wistar; Time Factors | 1997 |
Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
Topics: Abnormalities, Drug-Induced; Amiloride; Analysis of Variance; Animals; Arginine; Female; Fetal Death; Fetal Growth Retardation; Gestational Age; Guanidines; Limb Deformities, Congenital; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Inhibition of inducible nitric oxide synthase ameliorates endotoxin-induced gut mucosal barrier dysfunction in rats.
Topics: Animals; Bacteria; Blood Pressure; Endotoxins; Enzyme Inhibitors; Guanidines; Intestinal Mucosa; Lipopolysaccharides; Liver; Lymph Nodes; Male; Mitochondria; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen Consumption; Permeability; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spleen; Transcription, Genetic | 1997 |
Relative contributions of advanced glycation and nitric oxide synthase inhibition to aminoguanidine-mediated renoprotection in diabetic rats.
Topics: Administration, Oral; Albuminuria; Animals; Cohort Studies; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Immunohistochemistry; Kidney Glomerulus; Male; Methylguanidine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Enhanced mucosal permeability and nitric oxide synthase activity in jejunum of mast cell deficient mice.
Topics: Animals; Anti-Inflammatory Agents; Chromium Radioisotopes; Dexamethasone; Edetic Acid; Enzyme Inhibitors; Guanidines; Intestinal Mucosa; Jejunum; Male; Mast Cells; Mice; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxamic Acid; Permeability; Peroxidase | 1997 |
Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA Damage; Guanidines; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Culture Techniques | 1998 |
Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Guanidines; Iron; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Rats; Rats, Wistar | 1998 |
Clearance of Shigella flexneri infection occurs through a nitric oxide-independent mechanism.
Topics: Animals; Guanidines; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Respiratory Tract Infections; Shigella flexneri | 1998 |
Fasciola hepatica-induced immune suppression of spleen mononuclear cell proliferation: role of nitric oxide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Concanavalin A; Enzyme Inhibitors; Fascioliasis; Female; Guanidines; Immune Tolerance; Indomethacin; Liver; Lymphocyte Activation; Macrophages, Peritoneal; Male; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Spleen | 1998 |
Induction of apoptosis in murine macrophages by Mycobacterium tuberculosis is reactive oxygen intermediates-independent.
Topics: Animals; Apoptosis; Cell Line; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Macrophages; Mice; Mycobacterium tuberculosis; Nitric Oxide Synthase; Nitrites; Reactive Oxygen Species; Superoxides; Tuberculosis | 1998 |
Changes in nitric oxide production with lesion development in the gastric mucosa of rats with water immersion restraint stress.
Topics: Animals; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Immersion; Injections, Subcutaneous; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peptic Ulcer; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological | 1998 |
Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway.
Topics: Animals; Cell Hypoxia; Cells, Cultured; Cornea; Culture Media, Conditioned; Endothelial Growth Factors; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanidines; Interferon-gamma; Lactic Acid; Lipopolysaccharides; Lymphokines; Macrophages; Male; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Aminoguanidine reduces glomerular inducible nitric oxide synthase (iNOS) and transforming growth factor-beta 1 (TGF-beta1) mRNA expression and diminishes glomerulosclerosis in NZB/W F1 mice.
Topics: Animals; Body Weight; Cell Count; Creatine; Crosses, Genetic; Enzyme Inhibitors; Female; Guanidines; Hypertrophy; Kidney Glomerulus; Lupus Nephritis; Male; Mice; Mice, Inbred NZB; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Proteinuria; RNA, Messenger; Transforming Growth Factor beta | 1998 |
The induction of nitric oxide by interleukin-12 and tumor necrosis factor-alpha in human natural killer cells: relationship with the regulation of lytic activity.
Topics: Adjuvants, Immunologic; Antibodies; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Induction; Granzymes; Guanidines; Humans; Interferon-gamma; Interleukin-12; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Serine Endopeptidases; Tumor Necrosis Factor-alpha | 1998 |
Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride.
Topics: Animals; Arginine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Drug Interactions; Enzyme Inhibitors; Guanidines; Lipid Peroxidation; Liver; Liver Diseases; Liver Glycogen; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1998 |
iNOS contribution to the NMDA-induced excitotoxic lesion in the rat striatum.
Topics: Animals; Brain Injuries; Corpus Striatum; Dexamethasone; Dizocilpine Maleate; Guanidines; Male; N-Methylaspartate; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley | 1998 |
Effects of nitric oxide synthase inhibition in lipopolysaccharide-induced sepsis in mice.
Topics: Animals; Econazole; Enzyme Inhibitors; Female; Guanidines; Lipopolysaccharides; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Sepsis | 1998 |
Ethanol modulates induction of nitric oxide synthase in glial cells by endotoxin.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Enzyme Induction; Ethanol; Female; Guanidines; L-Lactate Dehydrogenase; Lipopolysaccharides; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1998 |
Relation of inducible nitric oxide synthase activity to lipid peroxidation and nonprotein sulfhydryl oxidation in the development of stress-induced gastric mucosal lesions in rats.
Topics: Animals; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Immersion; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Rats; Rats, Wistar; Stomach Diseases; Stress, Physiological; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 1998 |
In vivo blockage of nitric oxide with aminoguanidine inhibits immunosuppression induced by an attenuated strain of Salmonella typhimurium, potentiates Salmonella infection, and inhibits macrophage and polymorphonuclear leukocyte influx into the spleen.
Topics: Animals; Enzyme Inhibitors; Female; Guanidines; Immune Tolerance; Macrophages; Mice; Mice, Inbred C3H; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Salmonella Infections, Animal; Salmonella typhimurium; Spleen; Splenomegaly; Vaccination | 1999 |
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 1999 |
Brain dysfunction associated with an induction of nitric oxide synthase following an intracerebral injection of lipopolysaccharide in rats.
Topics: Analysis of Variance; Animals; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Cycloheximide; Enzyme Induction; Guanidines; Hippocampus; Kinetics; Lipopolysaccharides; Male; Maze Learning; Memory; Microdialysis; Microinjections; Motor Activity; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Organ Specificity; Rats; Rats, Wistar; Time Factors | 1999 |
Modulation of stress-induced gastric mucosal lesions by exogenous L-arginine.
Topics: Animals; Arginine; Gastric Mucosa; Guanidines; Lipid Peroxides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Stress, Physiological; Thiobarbituric Acid Reactive Substances; Time Factors | 1999 |
Nitric oxide increases hepatic arterial blood flow in rats with carbon tetrachloride-induced acute hepatic injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Guanidines; Hepatic Artery; Liver; Liver Circulation; Liver Diseases; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; RNA, Messenger | 1999 |
Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructosamine; Glycation End Products, Advanced; Guanidines; Immunohistochemistry; In Situ Hybridization; Kidney; Kidney Glomerulus; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staining and Labeling; Streptozocin; Tumor Necrosis Factor-alpha | 1999 |
Involvement of inducible nitric oxide synthase in stress-impaired testicular steroidogenesis.
Topics: Animals; Dihydrotestosterone; Enzyme Inhibitors; Guanidines; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Progesterone; Rats; Rats, Wistar; Restraint, Physical; Signal Transduction; Statistics, Nonparametric; Stress, Psychological; Testis; Testosterone; Time Factors | 1999 |
Nitric oxide production during endotoxin-induced mastitis in the cow.
Topics: Animals; Cattle; Cells, Cultured; Endotoxins; Enzyme Inhibitors; Escherichia coli; Female; Guanidines; Kinetics; Mastitis, Bovine; Milk; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites | 1999 |
The role of nitric oxide in experimental allergic conjunctivitis.
Topics: Adult; Albumins; Animals; Capillary Permeability; Codeine; Conjunctivitis, Allergic; Enzyme Inhibitors; Guanidines; Humans; Lipopolysaccharides; Mast Cells; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rabbits; Tears | 2000 |
Characterization of nitric oxide production following isolation of rat hepatocytes.
Topics: Animals; Antioxidants; Cell Separation; Enzyme Inhibitors; Gadolinium; Guanidines; In Vitro Techniques; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction | 2000 |
Carvedilol stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atenolol; Carbazoles; Carvedilol; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Guanidines; Heart; Interleukin-1; Isoproterenol; Muscle Proteins; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nucleic Acid Synthesis Inhibitors; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2000 |
Decreased nitric oxide levels stimulate osteoclastogenesis and bone resorption both in vitro and in vivo on the chick chorioallantoic membrane in association with neoangiogenesis.
Topics: Acid Phosphatase; Allantois; Animals; Biomarkers; Bone and Bones; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cells, Cultured; Chick Embryo; Chorion; Coculture Techniques; Enzyme Inhibitors; Guanidines; Isoenzymes; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Osteoclasts; Phenotype; Tartrate-Resistant Acid Phosphatase | 2000 |
Aminoguanidine prevents concanavalin A-induced hepatitis in mice.
Topics: Alanine Transaminase; Animals; Concanavalin A; Female; Guanidines; Hepatitis, Animal; Interferon-gamma; Liver; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; Tumor Necrosis Factor-alpha | 2000 |
Bacterial translocation during graft-versus-host disease after small bowel transplantation is reduced following inhibition of inducible nitric oxide synthesis.
Topics: Animals; Bacterial Translocation; Cytokines; Endotoxins; Enzyme Inhibitors; Graft Survival; Graft vs Host Disease; Guanidines; Intestine, Small; Lymphatic System; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Transplantation, Homologous | 2000 |
Role of nitric oxide in diabetes-induced attenuation of antinociceptive effect of morphine in mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Female; Guanidines; Male; Mice; Morphine; Nitric Oxide; Nitrites; Pain | 2000 |
Aminoguanidine reduces brain lesion volume after cold injury in the rat.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cold Temperature; Enzyme Inhibitors; Guanidines; Male; Nitrates; Nitrites; Osmolar Concentration; Rats; Rats, Inbred WKY | 2000 |
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma.
Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Guanidines; Interferon gamma Receptor; Interferon-gamma; Lysine; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Receptors, Interferon; Weight Loss | 2000 |
Subacute but not acute generation of nitric oxide in focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Corpus Striatum; Enzyme Inhibitors; Guanidines; Microdialysis; Nerve Degeneration; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Time Factors | 2000 |
Aminoguanidine reduces apoptosis of circulating V Beta 8.2 T lymphocytes in Lewis rats with actively induced experimental autoimmune encephalomyelitis. Association with persistent inflammation of the central nervous system and lack of recovery.
Topics: Animals; Apoptosis; Cell Division; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Gene Expression; Guanidines; Guinea Pigs; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-10; Myelin Basic Protein; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Recovery of Function; Spinal Cord; T-Lymphocytes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2000 |
Role of nitric oxide in hemorrhagic shock-induced bacterial translocation.
Topics: Animals; Bacterial Translocation; Blood Pressure; Enzyme Inhibitors; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Analysis; Time Factors | 2000 |
Mechanisms of salt-sensitive hypertension: role of inducible nitric oxide synthase.
Topics: Animals; Blood Pressure; Diuresis; Glomerular Filtration Rate; Guanidines; Hemodynamics; Hypertension; Kidney; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred Dahl; Reference Values; Renal Circulation; Sodium, Dietary | 2000 |
Detrimental effects of nitric oxide on mesenteric circulation during endotoxaemia and its reversal by aminoguanidine.
Topics: Acetylcholine; Algorithms; Analysis of Variance; Animals; Data Interpretation, Statistical; Endotoxemia; Enzyme Inhibitors; Female; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Mesentery; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phenylephrine; Random Allocation; Rats; Rats, Wistar; Splanchnic Circulation; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Altered endothelium-dependent responsiveness in the aortas and renal arteries of Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of non-insulin-dependent diabetes mellitus.
Topics: Acetylcholine; Animals; Aorta; Biological Factors; Blood Glucose; Body Weight; Cardiovascular Agents; Charybdotoxin; Diabetes Mellitus, Type 2; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indomethacin; Lipids; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Inbred OLETF; Renal Artery; Vasodilation | 2000 |
Levels of nitric oxide in the heart after experimental myocardial ischemia.
Topics: Animals; Chelating Agents; Coronary Vessels; Electron Spin Resonance Spectroscopy; Guanidines; Hemoglobins; Ligation; Male; Myocardial Ischemia; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Sorbitol; Spin Labels; Thiocarbamates | 2001 |
Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Enzyme Induction; Guanidines; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pancreatic Elastase; Rats; Rats, Wistar | 2001 |
Nitric oxide modulates excitation-contraction coupling in the diaphragm.
Topics: Animals; Diaphragm; Enzyme Inhibitors; Guanidines; Hindlimb; Indazoles; Male; Muscle Contraction; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley | 1998 |
TNF-alpha controls intracellular mycobacterial growth by both inducible nitric oxide synthase-dependent and inducible nitric oxide synthase-independent pathways.
Topics: Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Guanidines; Interferon-gamma; Intracellular Fluid; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium bovis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Signal Transduction; Tumor Necrosis Factor-alpha | 2001 |
Two different NO-dependent mechanisms account for the low virulence of a non-mycelial morphological mutant of Candida albicans.
Topics: Animals; Candida albicans; Candidiasis; Guanidines; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molsidomine; Mutagenesis; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Virulence | 2001 |
Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan.
Topics: Animals; Enzyme Inhibitors; Exudates and Transudates; Guanidines; Lipid Peroxidation; Liver; Lung; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Multiple Organ Failure; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peritonitis; Peroxidase; Poly(ADP-ribose) Polymerases; Rhodamines; Shock; Tyrosine; Zymosan | 2001 |
Nitric oxide participates in cataract development in selenite-treated rats.
Topics: Animals; Blotting, Western; Calcium; Cataract; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Fluorometry; Glutathione; Guanidines; Lens, Crystalline; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Sodium Selenite; Spectrophotometry, Atomic | 2001 |
Aminoguanidine exerts a beta-cell function-preserving effect in high glucose-cultured beta-cells (INS-1).
Topics: Animals; Cell Line; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Guanidines; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Nitrites; Pancreatic Neoplasms; Potassium Chloride; Proinsulin; Protein Precursors; RNA, Messenger; Spectrometry, Fluorescence; Time Factors; Transcription, Genetic | 2000 |
Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Chelating Agents; Ditiocarb; DNA Fragmentation; Enzyme Inhibitors; Free Radicals; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Guanidines; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitrites; RNA, Messenger; Superoxide Dismutase | 2001 |
Peripheral nitric oxide in carrageenan-induced inflammation.
Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflammation; Injections, Subcutaneous; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors | 2001 |
Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea pig airway.
Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Piperidines; Receptors, Neurokinin-2; Trachea | 2001 |
Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte.
Topics: Animals; Antioxidants; Arachidonic Acid; Arginine; Biological Transport; Catalase; Enzyme Inhibitors; Flow Cytometry; Free Radicals; Guanidines; Indazoles; Lipopolysaccharides; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.
Topics: Animals; Arginase; Arginine; Cattle; Cell Line; Fetal Blood; Guanidines; Humans; Hydrogen Peroxide; In Vitro Techniques; Macrophages; Macrophages, Alveolar; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2001 |
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2001 |
Modulation of leukocyte-endothelium interaction by nitric oxide synthase inhibitors: effects on leukocyte adhesion in endotoxin-induced uveitis.
Topics: Animals; Aqueous Humor; Blood Pressure; Cell Adhesion; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanidines; Leukocytes; Lipopolysaccharides; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred Lew; Uveitis | 2001 |
Immune modulation by fish kinetoplastid parasites: a role for nitric oxide.
Topics: Animals; Carps; Cell Division; Enzyme Inhibitors; Fish Diseases; Guanidines; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Phagocytosis; S-Nitroso-N-Acetylpenicillamine; Trypanosoma | 2002 |
Expression of inducible nitric oxide synthase in human umbilical vein endothelial cells during primary culture.
Topics: Blotting, Western; Cell Division; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Guanidines; Humans; Microscopy, Fluorescence; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Platelet Endothelial Cell Adhesion Molecule-1; Polymyxin B; Time Factors; Umbilical Veins | 2002 |
The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice.
Topics: Animals; Bacterial Infections; Blotting, Western; Decidua; Embryo Loss; Enzyme Activation; Enzyme Inhibitors; Female; Fibrinolysis; Guanidines; Immunohistochemistry; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pregnancy; Pregnancy Complications, Infectious; Uterus | 2003 |
Copper induces type II nitric oxide synthase in vivo.
Topics: Animals; Aorta; Blood Pressure; Copper; Guanidines; Immunoenzyme Techniques; Lipopolysaccharides; Liver; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2003 |
Role of inducible nitric oxide synthase in pig liver transplantation.
Topics: Animals; Aspartate Aminotransferases; Cold Temperature; Enzyme Inhibitors; Fluorescent Antibody Technique; Guanidines; Immunohistochemistry; Kupffer Cells; Liver; Liver Transplantation; Microscopy, Confocal; Necrosis; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Reperfusion; Swine; Tissue Preservation | 2003 |
Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria.
Topics: Animals; Chlorides; Creatinine; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Hypoalbuminemia; Isoenzymes; Kidney; Male; Nephrotic Syndrome; Nitrates; Nitric Oxide Synthase; Nitrites; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Serum Albumin; Sodium | 2003 |
The role of inducible nitric oxide synthase inhibitor on the arteriolar hyporesponsiveness in hemorrhagic-shocked rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression.
Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Gynostemma; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Plant Extracts | 2003 |
Effect of ornithine on the ileal histology, nitric oxide production and lipid peroxidation in LPS-induced endotoxemia.
Topics: Animals; Dose-Response Relationship, Drug; Endotoxemia; Enzyme Inhibitors; Female; Guanidines; Ileum; Lipid Peroxidation; Lipopolysaccharides; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Ornithine; Rats; Rats, Wistar | 2003 |
NO plays a role in LPS-induced decreases in circulating IGF-I and IGFBP-3 and their gene expression in the liver.
Topics: Analysis of Variance; Animals; Gene Expression; Growth Hormone; Guanidines; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Receptors, Somatotropin; RNA, Messenger | 2004 |
Nitric oxide synthase inhibitors modulate lipopolysaccharide-induced hepatocyte injury: dissociation between in vivo and in vitro effects.
Topics: Alanine Transaminase; Animals; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Hepatocytes; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Penicillamine; Rats; Rats, Wistar; RNA, Messenger; Tacrolimus; Tumor Necrosis Factor-alpha | 2003 |
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Guanidines; Injections, Intra-Articular; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Synovial Membrane; Synovitis; Tyrosine; Uric Acid; Zymosan | 2004 |
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 2004 |
Endogenous nitric oxide protects against T cell-dependent lethality during graft-versus-host disease and idiopathic pneumonia syndrome.
Topics: Animals; Bone Marrow Transplantation; CD4-Positive T-Lymphocytes; Female; Graft vs Host Disease; Guanidines; Lymphocyte Depletion; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Pneumonia; Radiation Chimera; Spleen; Superoxides; Syndrome; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tumor Necrosis Factor-alpha | 2004 |
Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Culture Media, Conditioned; Enzyme Activation; Enzyme Inhibitors; Female; Guanidines; Interferon-gamma; Interleukins; Lipid A; Macrophage Activation; Macrophages; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Radiation Tolerance; Tumor Necrosis Factor-alpha | 2004 |
Preservation of neurological functions by nitric oxide synthase inhibitors in conscious rats following delayed hemorrhagic shock.
Topics: Animals; Blood Pressure; Brain Chemistry; Cerebral Cortex; Enzyme Inhibitors; Guanidines; Male; Nervous System; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Analysis; Tetrazolium Salts | 2004 |
The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Heme Oxygenase-1; Hydralazine; Hypertension; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Protoporphyrins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2004 |
Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hyperbaric Oxygenation; In Vitro Techniques; Injections, Intravenous; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Random Allocation; Rats; Rats, Inbred WKY; Shock, Septic; Superoxides; Survival Rate; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2005 |
The role of selective nitric oxide synthase inhibitor on nitric oxide and PGE2 levels in refractory hemorrhagic-shocked rats.
Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Brain; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Guanidines; Immunoblotting; Kidney; Liver; Lung; Male; Nissl Bodies; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Sulfonamides; Survival Rate | 2005 |
Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Guanidines; Hypoxia; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2005 |
[Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].
Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hypertension, Pulmonary; Lung; Monocrotaline; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pulmonary Circulation; Rats; Rats, Wistar; Vasodilation | 2005 |
Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chromones; Cyclooxygenase 2; Dose-Response Relationship, Drug; Genes, Dominant; Genetic Vectors; Glomerular Mesangium; Guanidines; I-kappa B Kinase; Immunoblotting; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Morpholines; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Sulfonamides; Time Factors; Transfection; Up-Regulation | 2005 |
Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats.
Topics: Animals; Aorta, Thoracic; Body Weight; Cyclic N-Oxides; Enzyme Induction; Estradiol; Female; Glutathione Disulfide; Guanidines; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Ovariectomy; Ovary; Oxidative Stress; Oxygenases; Protoporphyrins; Rats; Spin Labels; Time Factors; Uterus | 2005 |
Immobilization stress causes extra-cellular oxidant-antioxidant imbalance in rats: restoration by L-NAME and vitamin E.
Topics: Analysis of Variance; Animals; Antioxidants; Behavior, Animal; Enzyme Inhibitors; Guanidines; Leukocytes; Lipid Peroxides; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Superoxides; Time Factors; Vitamin E | 2006 |
Collagen ultrastructure and TGF-beta1 expression preserved with aminoguanidine during wound healing in diabetic rats.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Epithelium; Extracellular Matrix Proteins; Fibroblasts; Gene Expression; Glycation End Products, Advanced; Guanidines; Immunohistochemistry; Lipid Peroxidation; Male; Microscopy, Electron; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Skin; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing; Wounds and Injuries | 2005 |
IFN-gamma: regulation of nitric oxide in the P. aeruginosa-infected cornea.
Topics: Animals; Colony Count, Microbial; Cornea; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Eye Infections, Bacterial; Female; Guanidines; Interferon-gamma; Keratitis; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pseudomonas aeruginosa; Pseudomonas Infections | 2006 |
Involvement of endogenous nitric oxide in myeloperoxidase mediated benzo(a)pyrene induced polymorphonuclear leukocytes injury.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Catalase; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Guanidines; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2006 |
Macrophage populations and cardiac sympathetic denervation during L-NAME-induced hypertension in rats.
Topics: Animals; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Heart; Hemodynamics; Hypertension; Macrophages; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympathetic Nervous System | 2006 |
Attenuation of morphine tolerance and dependence by aminoguanidine in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Dizocilpine Maleate; Drug Tolerance; Enzyme Inhibitors; Glutamates; Guanidines; Male; Mice; Morphine; Morphine Dependence; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Pain; Pain Measurement; Time Factors | 2006 |
Nitric oxide production by hepatocytes contributes to the inhibitory effect of endotoxin on insulin-like growth factor I gene expression.
Topics: Animals; Blotting, Northern; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Endotoxins; Gene Expression; Guanidines; Hepatocytes; Insulin-Like Growth Factor I; Kupffer Cells; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitrites; Penicillamine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Responsiveness to inhaled NO in isolated-perfused lungs from endotoxin-challenged rats is dependent on endogenous nitrite/nitrate synthesis.
Topics: Administration, Inhalation; Animals; Blood Pressure; Dose-Response Relationship, Drug; Guanidines; Isothiuronium; Lipopolysaccharides; Lung; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Perfusion; Rats; Rats, Sprague-Dawley | 2007 |
Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.
Topics: Alkylating Agents; Animals; Antioxidants; Azoles; Guanidines; Isoindoles; Lung Diseases; Male; Mechlorethamine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar | 2007 |
Effect of nitric oxide on phagocytic activity of lipopolysaccharide-induced macrophages: possible role of exogenous L-arginine.
Topics: Animals; Arginine; Guanidines; Lipopolysaccharides; Macrophages, Peritoneal; Male; Nitric Oxide; Nitrites; Phagocytosis; Rats; Rats, Wistar | 2007 |
Nitric oxide in prepubertal rat ovary contribution of the ganglionic nitric oxide synthase system via superior ovarian nerve.
Topics: Acetylcholine; Animals; Cholinergic Agents; Enzyme Inhibitors; Female; Ganglia, Sympathetic; Guanidines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ovary; Peripheral Nerves; Rats; Rats, Inbred Strains; Sexual Maturation | 2007 |
Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Blotting, Western; Cornus; Creatinine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Kidney; Kidney Cortex; Mitochondria; NF-kappa B; Nitrates; Nitrites; Proteinuria; Rats; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1; Weight Loss | 2007 |
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines; Hot Temperature; Male; Morphine; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Pain; Rats; Rats, Sprague-Dawley | 2007 |
In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion.
Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Guanidines; Hindlimb; Indomethacin; Ischemia; Male; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Random Allocation; Reperfusion; Reperfusion Injury; Vasodilator Agents | 2007 |
Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats.
Topics: Animals; Catalase; Colitis; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Intestine, Large; Lactones; Lipid Peroxidation; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Inbred Strains; Sulfones; Superoxide Dismutase; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2007 |
Effect of aminoguanidine on visual evoked potentials (VEPs), antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress.
Topics: Animals; Antioxidants; Brain; Catalase; Evoked Potentials, Visual; Glutathione Peroxidase; Guanidines; Lipid Peroxidation; Male; Neuroprotective Agents; Nitrates; Nitrites; Oxidative Stress; Random Allocation; Rats; Restraint, Physical; Retina; Stress, Psychological; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Visual Pathways | 2007 |
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Heme Oxygenase-1; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis | 2008 |
Isoflurane preconditioning reduces mouse microglial activation and injury induced by lipopolysaccharide and interferon-gamma.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Blotting, Western; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glutamic Acid; Guanidines; Interferon-gamma; Isoflurane; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase C; Tetrazolium Salts; Thiazoles | 2008 |
Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Deoxyguanosine; Diarrhea; Dose-Response Relationship, Drug; Guanidines; HeLa Cells; Humans; Intestinal Mucosa; Intestine, Small; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Tyrosine | 2009 |
Involvement of NO-cGMP pathway in anti-anxiety effect of aminoguanidine in stressed mice.
Topics: Adaptation, Ocular; Analysis of Variance; Animals; Anti-Asthmatic Agents; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Female; Guanidines; Interpersonal Relations; Male; Maze Learning; Mice; Nitric Oxide; Nitrites; Piperazines; Purines; Restraint, Physical; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sulfones | 2009 |
L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol.
Topics: Apoptosis; Arginine; Cell Line; Cell Survival; Endothelial Cells; Enzyme Inhibitors; Glutathione Peroxidase; Guanidines; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroarginine; Oxidative Stress; Propofol; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Involvement of nitric oxide in maneb- and paraquat-induced Parkinson's disease phenotype in mouse: is there any link with lipid peroxidation?
Topics: Animals; Corpus Striatum; Guanidines; Lipid Peroxidation; Male; Maneb; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Paraquat; Parkinson Disease, Secondary; Pesticides; Phenotype; RNA, Messenger; Second Messenger Systems; Tyrosine 3-Monooxygenase | 2010 |
GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice.
Topics: Animals; Anti-Anxiety Agents; Brain; Curcumin; Diazepam; gamma-Aminobutyric Acid; Guanidines; Maze Learning; Mice; Nitric Oxide Synthase; Nitrites; Restraint, Physical; Social Behavior | 2010 |
Differential effects of nitric oxide synthase inhibitors on anxiety in unstressed and stressed mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Darkness; Enzyme Inhibitors; Guanidines; Indazoles; Light; Maze Learning; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Pyrrolidines; Restraint, Physical; Stress, Psychological; Thiocarbamates | 2010 |
Effect of aminoguanidine on the conjunctival histamine and nitrite levels in experimental conjunctivitis.
Topics: Amine Oxidase (Copper-Containing); Animals; Conjunctiva; Conjunctivitis; Cromolyn Sodium; Guanidines; Histamine; Male; Mast Cells; Nitric Oxide Synthase; Nitrites; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar | 2011 |
Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.
Topics: Animals; Antidepressive Agents; Ellagic Acid; Emotions; Fenclonine; Fluoxetine; Guanidines; Hindlimb Suspension; Immobilization; Indazoles; Male; Mice; Motor Activity; Nitrites; Prazosin; Restraint, Physical; Stress, Psychological; Sulpiride; Swimming | 2012 |
Nitric oxide mediates the insulin sensitizing effects of β-sitosterol in high fat diet-fed rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Guanidines; Hepatocytes; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Sitosterols | 2013 |
The stimulated innate resistance event in Bordetella pertussis infection is dependent on reactive oxygen species production.
Topics: Acetylcysteine; Animals; Bacterial Load; Bordetella Infections; Bordetella pertussis; Guanidines; Immunity, Innate; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitric Oxide Synthase; Nitrites; Reactive Oxygen Species; Time Factors; Toll-Like Receptor 4 | 2013 |
Possible involvement of GABAergic and nitriergic systems for antianxiety-like activity of piperine in unstressed and stressed mice.
Topics: Alkaloids; Animals; Anti-Anxiety Agents; Anxiety; Benzodioxoles; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Guanidines; Indazoles; Male; Maze Learning; Mice; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Piperidines; Polyunsaturated Alkamides; Stress, Psychological | 2014 |
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction | 2015 |
Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.
Topics: Animals; Antidepressive Agents; Colitis; Colon; Crohn Disease; Depression; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hippocampus; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Signal Transduction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2016 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors | 2016 |
Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS.
Topics: Acute Kidney Injury; alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Kidney; Lung; Male; Malondialdehyde; Nephrectomy; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Reabsorption; Reperfusion Injury; Respiration; Urination Disorders | 2016 |
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Drug Synergism; Fluoxetine; Guanidines; Hippocampus; Immobility Response, Tonic; Indazoles; Male; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prefrontal Cortex; Selegiline; Signal Transduction; Sildenafil Citrate; Swimming | 2018 |
Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine.
Topics: Animals; Anti-Anxiety Agents; Blotting, Western; Brain-Derived Neurotrophic Factor; Escape Reaction; Guanidines; Male; Maze Learning; Motor Activity; Nitric Oxide Synthase; Nitrites; Panic; Periaqueductal Gray; Phosphorylation; Rats; Rats, Wistar; Receptor, trkB; Signal Transduction | 2019 |
Soluble Fraction from Lysates of Selected Probiotic Strains Differently Influences Re-Epithelialization of HaCaT Scratched Monolayer through a Mechanism Involving Nitric Oxide Synthase 2.
Topics: Bacteria; Enzyme Inhibitors; Guanidines; Humans; Keratinocytes; Nitric Oxide Synthase Type II; Nitrites; Probiotics; Re-Epithelialization; Solubility | 2019 |
High-refined carbohydrate diet consumption induces neuroinflammation and anxiety-like behavior in mice.
Topics: Adipose Tissue; Animals; Anxiety; Behavior, Animal; Dietary Carbohydrates; Disease Models, Animal; Guanidines; Hippocampus; Inflammation; Leptin; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Nitrites; Prefrontal Cortex | 2020 |